Conjunctivitis

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DISEASES OF THE CONJUNCTIVA

ODONGO SHADRACK(MBChB)
Review: Anatomy of the Eyeball
Eye Ball
Conjunctivitis
• Inflammation of the conjunctiva
• Most common disease of conjunctiva & eye
• Common in hot climates because of
– Warm humid environment
– Dust and solar radiations cause irritation
– Insect vectors transmit dx
– Poverty: overcrowding, poor ventilation, poor
hygiene are risks factors
Aetiology
1. Infections
a. Bacterial ; Viral; Trachoma;
b. Granulomatous: TB, Syphilis, Myiasis, parasites
• Bacterial most common
– Primary: invade healthy conjunctiva- virulent org
• Staph. Haemo. GC, strept
– Secondary
• When conj defences against infection are weakened
• Eg. eyelid abn, lacrimal dx, KCS, conjunct abn: VAD
Aetiology
• Viral:
a. Most common is adenovirus
Others measles, molluscum contagiosum, Herpes simplex,
herpers zooster, Ebola, corona viruses
b. Viruses live in the epithelium hence invade
cornea
2. Allergy / vernal conjunctivitis
• Vernal conjunctivitis
• Drugs and cosmetics
Aetiology
3. Physical and chemical irritants
• Acids, alkali, other chemicals
• Foreign body, trauma
4. Nutritional:
– VAD
5. Endogenous:
– Dry eye / KCS;
6. Secondary: dacryocystitis; TT; exposure, CVII palsy
Aetiology
7. Psychological
• Tension
• Anxiety
• Depression
Clinical Features
• Discomfort
– Few nerve supply hence pain not a prominent
– Irritation
– Itching
– Significant pain indicates associated diseases like
corneal involvement especially in viral infection
• Visual symptoms
– Usually no visual impairment
– Reduced vision is due to secretions, corneal spread
• Itching: allergy
Clinical Features /Signs
1. Red eye
– Vasodilatation; spread out / diffused.
2. Increased secretions cause by
• irritation and reflex tear production
• Protein exudation and vascular leakage
– Purulent / mucopurulent: bacterial infections
– Watery/ serous: viral
– Thick sticky mucous: chronic allergic
conjunctivitis
– Slightly mucpurulent
Clinical Features /Signs
3. Oedema / chemosis
4. Follicles
– Due presence of lymphoid tissues under the epithelium
– Lymphoid tissues enlarge esp in viral infections
5. Papillae
– Raised areas on the surface of the epithelium
– Caused by vessels and inflammatory cells grpowing in the
subconjunctival space
– Found in the tarsal conjunctiva and (near limbus)
Clinical Features /Other signs
• Keratinization
– Conjunctival epithelium produces keratin which and
so becomes hard and unwettable
• Membrane formation
– Formed from inflammatory cell and fibrin
– Forms a plague which covers and sticks to conjunc
– Indicates severe adenoviral infection
• Scaring fibrosis: end result of any inflammatn
• Increased pigmentation: severe allergy & VAD
Read
• Clinical features of each

– Bacterial conjunctivitis
– Viral conjunctivitis
– Allergic conjunctivitis
• Vernal catarrh
• Reactive conjuntivitis
– Note : papillae and follicles
Treatment
• Bacterial • Allergic
– Antibiotics drops &
– Topical steroids
ointments
• Gentamycin,
– Mast cells stabilizers
chloramphenicol, Sodium Cromoglycate drops
erythromycin, – Topical cyclosporine
crprofloxacin, ofloxacin,
Moxifloxacin, neomycin
– Anti histamine
etc • Oloptadine eye drops
– Hygiene • Loratadine and its
derivatives tablets
– Avoid padding
– Oral steroids (in severe
cases)
– Artificial tear drops, Zinc
eye drops
TREATMENT

• Viral
– Usually self limiting
– Few antiviral ointment
• Acyclovir
• gancyclovir
– Prophylactic antibiotics
– Molluscum : excision
– DO NOT GIVE A STEROID
DROP IN VIRAL
INFECTIONS
Read /Clerk/clinic
• Conjunctival Tumours
– Squamous cell Ca
– Pterygium
– Pingecula
– Nivea
– Other conjunctival growths
References
• Eye diseases in hot climates 3rd, 4th and 5th
Editions (Sanford Smith)

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