MALÁRI

A🦟
Pontos chaves para
abordagem do paciente
pediátrico na urgência
 Principais abreviaturas
●ACT: derivados de artemisina
●AL: Artemeter+Lumefantrina
●DNSP: direção nacional de saúde pública
●LRA: lesão renal aguda
●PfHRP2: plasmódium falciparum histidine-rich-
protein 2
●PfEMP1: Proteína 1 da membrana eritrocitária do
plasmódium falciparum
●TDR: teste de diagnóstico rápido
 Malária
Picada do mosquito anopheles Cinco Protozoários:

1. Falciparum incubação( 10-12 dias)

2. Vivax Incubação ( 14 Dias)

3. Malariae incubação ( 30 dias)

4. Ovale Incubaçao (14 Dias)

5. Knowlesi Incubaçao ( 12 Dias)

 Classificação
OMS
● Malária simples ou não complicada : presença de sinais e
sintomas sem sinais clínicos ou laboratoriais que indiquem
gravidade ou disfunção vital dos órgãos

● Malária grave ou complicada : dois ou mais dos seguintes:

Alteração da consciência, prostração, convulsões, acidose,
hipoglicemia, anemia grave, insuficiência renal, icterícia, edema
pulmonar, sangramento significativo, choque, hiperparasitemia
 Diagnóstico
● EXAME PADRÃO OURO: GOTA DE SANGUE ESPESSA E
EXTENSÕES FINAS

● RECOMENDA-SE A REALIZAÇÃO DO TDR A TODOS OS PACIENTES

DE CLÍNICA SUGESTIVA, SEGUIDO DE TESTE DE MICROSCÓPIA
PARA CONFIRMAÇÃO E QUANTIFICAÇÃO DA PARASITEMIA.

● Os TDR para detectar PFHRP2 PODEM SER ÚTEIS PARA

PACIENTES QUE RECEBEM TRATAMENTO ANTIMALARICO
INCOMPLETO, NOS QUAIS OS ESFREGAÇO DE SANGUE PODEM
SER NEGATIVOS. ISSO PODE ACONTECER SE O PACIENTE TIVER
RECEBIDO UMA DOSE DE ACT
 TABLE OF CONTENTS

01the
About 02 03
RECOMMENDAT
Disease DIAGNOSIS IONS
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topic of the section here topic of the section here topic of the section here

05 04 06
PATHOLOGY TREATMENT CONCLUSIONS
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topic of the section here topic of the section here topic of the section here
Tto. (A-L- 20/120mg)
Artesunato – Amodiaquina (AS-AQ)
Dihidroartemisinina + piperaquina (DHA- PPQ) (40/320 MG)
 Tto malária grave

Doses.
• Para menores de 20kg -3mg/kg
• Para maiores de 20 kg – 2,4mg/kg
 Manejo das complicações

Anemia severa (definida como Hct: menor ou igual a 15% Ou Hb menor de

5g/dL
Malária cerebral
HIPOGLICEMIA
Insuficiência renal aguda
0 About
the
Disease
1
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here if you need it
A PICTURE
IS WORTH
A
THOUSAND
WORDS
 ABOUT THE DISEASE

Mars Jupiter Saturn

Despite being red, It’s a gas giant and Yes, this is the
Mars is actually a the biggest planet ringed one. It’s a
cold place in the Solar System gas giant
 ABOUT THE DISEASE

Mercury is the closest Despite being red, Mars is

planet to the Sun actually a cold place

Venus has a beautiful Jupiter is the biggest

name, but it’s hot planet in the Solar System
 REFERENCES

● AUTHOR (YEAR). Title of the publication. Publisher

● AUTHOR (YEAR). Title of the publication. Publisher
● AUTHOR (YEAR). Title of the publication. Publisher
● AUTHOR (YEAR). Title of the publication. Publisher
● AUTHOR (YEAR). Title of the publication. Publisher
● AUTHOR (YEAR). Title of the publication. Publisher
228.000.00
0
Cases of malaria in the world
 ABOUT THE DISEASE

10% 30% 25% 50%

Mercury is the Venus has a Mars is actually Neptune is the

smallest planet beautiful name a cold place farthest planet
 SYMPTOMS OF THE DISEASE

SATURN JUPITER
Saturn is the Jupiter is the
ringed one biggest planet

MARS NEPTUNE
Despite being Neptune is the
red, it’s cold farthest planet
 CONCEPTS AND TYPOLOGIES

type 1 type 2 type 3

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concepts concepts concepts

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concepts concepts concepts

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concepts concepts concepts
TREATMENT

VENUS
Venus has a beautiful
Name, but it’s hot

MERCURY
Mercury is the closest
planet to the Sun
 TREATMENT
Jupiter is the
DAY biggest one DAY Neptune is the
farthest one
1 3

DAY
Despite being Venus has a DAY
2
red, Mars is beautiful name 4
cold
PATHOLOGY

Venus JUPITER Mercury

Despite its beautiful Jupiter is a gas giant and Mercury was named
name, its atmosphere is the biggest planet in the after the Roman
poisonous Solar System messenger god
 RISK FACTORS
Venus Mars

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change the data and paste
the resulting graph here,
replacing this one
 KEY NUMBERS

2018 2017
228 231
millions
Mercury is the closest
planet to the Sun
millions
Venus is the second
planet from the Sun
MOCKUP

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the screen with your own work.
Just delete this one, add yours
and center it properly
 “This is a quote,
Words full of
wisdom that
someone important
said and can make
—Someone Famous
the reader get
inspired.”
0 DIAGNO
SIS
2
You could enter a subtitle
here if you need it
 DIAGNOSIS

MERCURY VENUS MARS

Mercury is the closest Venus is the second Despite being red, Mars
planet to the Sun planet from the Sun is actually a cold place

JUPITER SATURN NEPTUNE

It’s the biggest planet Saturn is composed of Neptune is the farthest
in the Solar System hydrogen and helium planet from the Sun
 PREVENTION

MARS JUPITER
Despite being red, Mars Jupiter is a gas giant
is actually a cold place and the biggest planet

VENUS NEPTUNE
Venus is the second Neptune is the farthest
planet from the Sun planet from the Sun
 RECOMMENDATIONs

WHAT to What to
avoid do
● You can describe what the ● You can describe what the
patient shouldn’t do here patient should do here
● You can describe what the ● You can describe what the
patient shouldn’t do here patient should do here
● You can describe what the ● You can describe what the
patient shouldn’t do here patient should do here
PREVALENCE

SATURN
Saturn is the
ringed planet

JUPITER
Jupiter is the
biggest planet
CONCLUSIONS

Research conclusions
Mercury is the closest planet to the Sun
and the smallest one in the Solar System
—it’s larger than the Moon
 OUR TEAM

DR. JENNA DR. JOHN DR. RICHARD

You canDOE
replace the JAMES
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replace the
image on the screen image on the screen image on the screen
 KEY NUMBERS

50, Venus has a beautiful

000
name, but it’s hot

20,0 Saturn is a gas giant

00
and has several rings

5,500 Neptune is far away

from Earth
 THAN
KS!
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