THE BREAST 1
THE BREAST 1
THE BREAST 1
Clifford Owobu
• Relevant Anatomy
• Clinical Presentation of breast lesions
• Inflammatory breast diseases
• Benign breast lesions
• Breast cancer
• Breast cancer screening
MICROANATOMY
• 6 – 10 major ducts
• Lining:
Keratinizing Strat
sq. epithelium
Double-layered
epithelium
Stages of breast
development
MICROANAT
OMY
• Lobes
• Lobules
• Glands/Acini
• Cells
• Stromal
MICROANATOMY
Two major structures:
Ducts
Lobules
Nutritional support
and survival of infants
FUNCTION OF
THE FEMALE
BREAST
Sociocultural
importance
=> Femininity
FUNCTION OF THE
FEMALE BREAST
Symbol of beauty
FUNCTION OF THE
FEMALE BREAST
Erogenous organ
CLINICAL PRESENTATION OF BREAST
DISSEASE
SYMPTOMS OF PATIENTS PRESENTATIONS OF BREAST CANCERS
CLINICAL PRESENTATION OF BREAST
DISSEASE
NIPPLE DISCHARGE • Bloody
• Normal o Large duct papillomas, cysts (+/-
serous discharge)
• Milky o Pregnancy
o Endocrine causes e.g., pit o Cancers
adenoma, hypothyroidism
NB: Discharge in older women that
o Drugs: OCP, tricyclic is spontaneous, unilateral, and
antidepressant, methydopa bloody is likely to have a malignant
o Repeated nipple stimulation origin
CLINICAL PRESENTATION OF BREAST
DISSEASE
PALPABLE MASSES INFLAMMATORY CHANGES
• Benign/malignant lesions LUMPINESS
• Xtics
• Relationship to age and
quadrants NB: Symptoms/signs =>
• Usefulness in screening Anxiety; Existential crisis
PAIN
• Cyclical/non-cyclical
DISEASES OF THE
BREAST
Developmental disorder
Inflammatory
Benign epithelial
Carcinoma
Stromal tumours
DISEASES OF THE
BREAST
Summary