Stephen Marley covered the song on his album Mind Control.
Van Morrison covered this song on his 1993 album Too Long in Exile, and later included it in the double live album A Night in San Francisco as the first song in a medley that lasted just under 15 minutes. Biographer John Collis says: "The 15-minute sequence billed as 'Lonely Avenue/4 O'Clock in the Morning (Try for Sleep)', does indeed begin with the Pomus song and includes the Morrison blues in the title, but also wheels on Jimmy Witherspoon for his own medley and also throws in passing quotes from 'Be Bop a Lula', Sly Stone's 'Family Affair' (with Jonn Savannah contributing a falsetto) and Roy Orbison's 'Down the Line' among other references."[5]
Merl Saunders and Friends covered this song on the 1972 album Fire Up Plus.
James Booker covered the song on his album Classified.
On April 18, 2011, musician Ben Waters released the album Boogie 4 Stu, a tribute to the late Rolling Stones pianist Ian Stewart, including a version of "Lonely Avenue".
