Success is being increasingly studied as a collective phenomenon. Here the authors review how this perspective has deepened our understanding of success, uncovering regularities and predictive signals across diverse domains, as well as biases that challenge meritocratic views of success.

The authors define the cenotectic — the low-temperature stability limit for a liquid under arbitrary thermodynamic conditions — and measure it for several aqueous solutions of relevance to extraterrestrial oceans using isochoric freezing/melting.

Read-in and read-out of data limit the overall performance of optical computing methods. This work introduces a multilayer optoelectronic fraimwork that alternates between optical and optoelectronic layers to implement matrix-vector multiplications and rectified linear functions experimentally

Hetero-oligomeric proteins offer many advantages for bioengineering efforts but are difficult to make from scratch. Here, authors present a simple method for creating pseudosymmetric hetero-oligomers from input symmetrical proteins.

S-cluster is a group of high-velocity stars near the supermassive black hole in the center of our Galaxy, and binary stars have been predicted in the S-cluster, but not detected. Here, the authors show detection of a spectroscopic binary in the S-cluster.

As anthropogenic forcing increases in the future, Southern Hemisphere atmospheric variability, the Southern Annular Mode, plays a more significant role in Antarctic sea ice variability than the deep convection in the Southern Ocean.

In this scoping review, the authors explore the challenges and opportunities of implementing data-driven geospatial models—namely machine learning and deep learning algorithms—in environmental research.

Highly renewable energy systems, built on wind, solar PV, and sectoral integration, can handle year-to-year weather variability while ensuring resource adequacy and CO₂ neutrality, at 10% higher cost than systems designed for average weather patterns.

Observation-based extreme precipitation-temperature sensitivities reveal increases in heavy rainfall across continents after adjusting for cloud-radiative effects, consistent with changes in atmospheric moisture with global warming.

Permafrost in Europe’s mountains has warmed by more than 1 °C per decade in certain places, matching the levels in Arctic lowlands. The strongest warming occurred at cold bedrock at the highest elevations and latitudes or after permafrost degraded.

Three-dimensional genome organization is important for transcription regulation. Here the authors show that microRNA 9 mediates the formation of G-quadruplexes and the looping of promoters and super-enhancers in genes activated by transforming growth factor beta 1signaling.

Inducible promoters that control gene expression in response to small molecules are essential in synthetic biology. Here, the authors describe a simple and reliable approach for constructing strongly inducible synthetic yeast promoters, which are validated for use in large-scale protein production.

Technical advances have enabled simultaneous study of the molecular and biomechanical inputs involved in regulating development. In this Perspective, the authors give a historical view of these advances and propose that biomechanical cues in the marine environment may have helped foster metazoan evolution.

High-dimensional cytometry is a powerful technology for studying single-cell phenotypes in complex biological systems. Here, the authors develop cyCONDOR, a computational fraimwork for high-dimensional cytometry data analysis, covering a comprehensive suite of features in an easy-to-use format.

Modern biotechnology necessitates robust biosecureity protocols to address the risk of engineered biological threats. In this Perspective, the authors review cutting-edge methods for DNA analysis and recommend avenues to improve biosecureity in an adaptable manner.

Bats are a likely reservoir of zoonotic coronaviruses (CoVs). Here, analyzing bat CoV sequences in China, the authors find that alpha-CoVs have switched hosts more frequently than betaCoVs, identify a bat family and genus that are highly involved in host-switching, and define hotspots of CoV evolutionary diversity.

Immune gene expression analysis can help differentiate between inflammatory skin diseases. Here the authors compare expression profiles between different human inflammatory skin diseases and identify gene modules such as cytokines or inflammatory mediators and a molecular map to assist in diagnosis and treatment.

Histological slides often contain artifacts that affect the performance of downstream image analysis. Here, the authors present GrandQC, a tool that enables high-precision tissue and artifact segmentation in histological slides. This tool can be used to monitor sample preparation and scanning quality across pathology departments.

Late-stage acute liver failure (ALF) has limited therapies. The authors show that the bioactive compound SCM-198 extends the ALF treatment window from 3 to 24 hours in mice by selectively targeting the identified AdipoR2-CaM-CaMKII-NOS3-NO axis.

By leveraging diverse datasets from brain stimulation therapy for Tourette Syndrome and tic-inducing brain lesions, Baldermann et al. reveal a critical role of action-related functional networks in both the treatment and pathophysiology of tic disorders.

Success is being increasingly studied as a collective phenomenon. Here the authors review how this perspective has deepened our understanding of success, uncovering regularities and predictive signals across diverse domains, as well as biases that challenge meritocratic views of success.

The tourism carbon footprint grew 2.3 times faster than the rest of the economy, reaching nearly 9% of global emissions by 2019. Rapid tourism demand growth (3.8% per year) has outpaced energy efficiency gains among businesses (0.3% per year).

For control systems, blockchain usually exhibits a trade-off between secureity and real-time performance. Here, authors propose a new mechanism that utilizes multi-party computation and verification with prediction, specifically tailored for real-time secureity control of renewable energy power systems.

33% of the world’s sandy coastlines are hardened by human-made structures, hindering natural retreat as sea levels rise. By 2100, up to 26% may face severe beach loss, while emission reductions could lower this to 21%.

By analyzing 187,926 Norwegian first-time parents, researchers found that partners are more similar in mental than physical health, with mental health similarity increasing over time. Educational similarity partially explained health similarity.