The Neuroscience Research Priority Area and UK Center for Clinical and Translational Science (CCTS) are now accepting applications for Neuroscience related Pilot Projects. The purpose of this funding mechanism is to provide a new opportunity and resources to support innovative, collaborative research relevant to the health challenges and disparities faced by the nation and the citizens of Kentucky. There are 2 awards included in this RFA: The CCTS/NRPA Collaborative Pilot Award providing up to $50,000 in funding for clinical and translational projects and the NRPA Pilot Award supporting awards of $25,000.

Dates & Deadlines

• LOI due date:

  Thu, 08/25/2022 - 5pm

Downloads

• 2022 Neuroscience and N-RPA/CCTS Collaborative RFA

Alliance for Reduction of Diabetes Associated Microvascular Dysfunction (ADAM)  Pilot Grant Program

Request for Applications

The Alliance for Reduction of Diabetes Associated Microvascular Dysfunction (ADAM) seeks to assist clinicians and basic science scientists at the University of Kentucky to facilitate planning and implementation of focused collaborations in neurovascular/cardiovascular metabolism-related research, training, career development, education, and/or outreach. The pilot grants will provide support for neurovascular metabolism research projects for limited durations of time to perform feasibility studies and obtain preliminary data that will lead to the submission of specific competitive grant applications for support by the NINDS and/or other sources of funding. The pilots are targeted to junior clinical faculty and successful grantees will be paired with a faculty mentor from ADAM.

Proposed projects should involve clinicians and basic science scientists and centered on the following research themes:

• correlation of metabolic and inflammatory mediators of microvascular dysfunction in peripheral tissues with cerebral small vessel ischemic;
• correlation of metabolic and inflammatory mediators of microvascular dysfunction with ischemic heart failure;
• metabolic and inflammatory mediators of clot formation.

Application Format

Applications should include the following documents. Completed applications should be submitted to NeuroscienceRPA@uky.edu

1.Completed Application Form including:

      a. Study Background (1 page)

      b. Study Design (2-pages)

      c. Budget and Budget Justification

      d. Plan for extramural funding (1 page)

      e. Signature Page

2. NIH-type Biographical Sketch (https://grants.nih.gov/grants/forms/biosketch.htm)

3. Documentation of IACUC or IRB submission or approval as applicable (applicants do not need IRB or IACUC approvals to submit a pilot grant application; successful applicants will need to submitany necessary IRB or IACUC protocols within two weeks of award notification and provide theNRPA with documentation of the submission).

4. Letters of support as applicable

Budget

The pilot grant program will support 2 grants of approximately $25,000 in direct costs each for a 1-year project period. Projects requiring higher levels of funding are still encouraged to submit an application; the ADAM’s goal is to support the most promising research and may award increased levels of funding to projects as appropriate and with justification, depending on availability of funds.

The following costs are not covered: administrative or office costs, meals or hospitality, travel that is not directly related to the conduct of research, other items typically supported by indirect costs, and monetary clinic incentives.

Review Process

Grant applications will be reviewed by investigators with appropriate neuroscience background and expertise and will use NIH-type evaluations (https://grants.nih.gov/grants/peer/guidelines_general/scoring_system_and_procedure.pdf) . Applications will also be evaluated based on the potential for the proposal to eventually be competitive for extramural support. Following initial peer review, applications recommended for funding will be reviewed by the Alliance and final funding decisions made by joint agreement.

Review Criteria

Application review will based on the following considerations:

1. Innovation

2. Significance

3. Approach

4. Environment

5. Investigators

6. Probability that this project will lead to extramural funding

7. Additional review considerations:

a. Budgetary considerations

b. Regulatory approvals

c. Letters of support/commitment (if applicable)

Due Dates:

• Call For Applications: December 8, 2021
• Application Deadline: February 1, 2021, 5:00pm EDT
• Funding Decision: February 22, 2021 (tentative)
• Funding cycle: March 1, 2021- February 28, 2022*
• Subject to change in response to the impact of coronavirus

Notifications

Reviews and award notifications will be provided within 3-weeks of the grant application deadline.

Term

Funding is for 1 year beginning March 1, 2021 and ending February 28, 2022. *Subject to change in response to the impact of coronavirus

Awardee Responsibilities:

• Awardees are expected to submit collaborative extramural grants
• Awardees are expected to publish their findings in scholarly peer-reviewed journals and present their research at professional meetings
• All publications, grants, and presentations resulting from research funded by the ADAM should cite the ADAM as a contributing source of support

A 1-page report summarizing the outcome of the project, extramural funding applications and awards, and the use of the awarded funds is due 1 month after the end of the funding period. Unspent funds are to be returned to the program. Extensions are not allowed.

Fall 2020 Request for Applications

The Fall 2020 NRPA Pilot Grant application is now open. For this round of funding, applications should be submitted via the VPR's funding portal:

Pilot Grant Portal 

Any questions may be directed to Susannah Stitzer: susannahmstitzer@uky.edu 

Description of Program

The Neuroscience Research Priority Area (NRPA) seeks to provide broad-based support of neuroscience research across the University of Kentucky. As part of this initiative, the NRPA has implemented a pilot grant program to support the development of innovative, cutting-edge research across basic, translational, and clinical neurosciences and to facilitate the development of collaborative teams of basic scientists, translational scientists, clinical investigators, and clinicians across colleges, departments, and disciplines. The pilot grants will support teams in developing preliminary data necessary for applications for extramural funding. Proposed projects should be multidisciplinary or transdisciplinary and involve colleague(s) from more than one UK College/Department. Faculty, resident, post-docs, and fellows are all invited to apply.

Application Format

Applications should include the following documents. Applications are to be submitted through the Pilot Grant Portal.

1. Completed Application Form including:

   1. Study Background (1 page)

   2. Study Design (2-pages)

   3. Budget and Budget Justification

   4. Plan for extramural funding (1 page)

   5. Signature Page

2. NIH-type Biographical Sketch (https://grants.nih.gov/grants/forms/biosketch.htm)

3. Documentation of IACUC or IRB submission or approval as applicable (applicants do not need IRB or IACUC approvals to submit a pilot grant application; successful applicants will need to submit any necessary IRB or IACUC protocols within two weeks of award notification and provide the NRPA with documentation of the submission).

4. Letters of support as applicable

Budget

The pilot grant program will support 2 grants of approximately $25,000 in direct costs each for a 1-year project period.  Projects requiring higher levels of funding are still encouraged to submit an application; the NRPA’s goal is to support the most promising research and may award increased levels of funding to projects as appropriate and with justification, depending on availability of funds.

The following costs are not covered –administrative or office costs, meals or hospitality, travel that is not directly related to the conduct of research, other items typically supported by indirect costs, and monetary clinic incentives.

Support for Protocol Design

For researchers seeking assistance in study design, please contact Dr. Christopher McLouth via the NRPA website (research.uky.edu/neuroscience) or CCTS’ BERD services via the CCTS website.

Review Process

Grant applications will be reviewed by investigators with appropriate neuroscience background and expertise and will use NIH-type evaluations (https://grants.nih.gov/grants/peer/guidelines_general/scoring_system_and_procedure.pdf) . Applications will also be evaluated based on the potential for the proposal to eventually be competitive for extramural support. Following initial peer review, applications recommended for funding will be reviewed by the NRPA Internal Advisory Council and final funding decisions made by joint agreement.

Review Criteria

Application review will based on the following considerations:

1. Innovation

2. Significance

3. Approach

4. Environment

5. Investigators

6. Probability that this project will lead to extramural funding

7. Additional review considerations:

   1. Alignment with NRPA strategic goals

   2. Budgetary considerations

   3. Regulatory approvals

   4. Letters of support/commitment (if applicable)

Unfunded Grants

Unfunded grants can be considered for funding in subsequent cycles.

Due Dates

• Call For Applications: October 16, 2020

• Application Deadline: December 11, 2020, 5:00pm EDT

• Funding Decision: January 8, 2020 (tentative)

  • Funding cycle: February 1, 2021 - January 31, 2022 (subject to impacts from the coronavirus)

Notifications

Reviews and award notifications will be provided within 8-weeks of the grant application deadline.

Term

Funding is for 1 year beginning February 1, 2020 and ending January 31, 2021 (subject to impacts from the coronavirus).

Awardee Responsibilities

• Awardees are expected to submit collaborative extramural grants

• Awardees are expected to publish their findings in scholarly peer-reviewed journals and present their research at professional meetings

• All publications, grants, and presentations resulting from research funded by the NRPA should cite the NRPA as a contributing source of support

A 1-page report summarizing the outcome of the project, extramural funding applications and awards, and the use of the awarded funds is due 1 month after the end of the funding period. Unspent funds are to be returned to the program. Extensions are not allowed.