These data were calculated to estimate seismic hazard, risk, and design across South America using the latest data, models, and methods. The input data to the model, as well as the output data are available here. The input data includes a seismicity catalog, seismicity rate models, evaluation of earthquake sizes, fault geometry and rate parameters, and ground-motion models. Output data include hazard curves, and associated products, for peak ground acceleration and spectral accelerations at 0.2 and 1 s periods.