Highlights

  • Evolutionary interplay

    The evolutionary history of a family of beetles called Belidae has been influenced by the breakup of the supercontinent Gondwana and the rise of angiosperms.

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    Research Article
  • Targeting a methyltransferase

    The SARS-CoV-2 main protease targets an enzyme called TRMT1 that modifies transfer RNA.

    Angel D'Oliviera, Xuhang Dai ... Jeffrey S Mugridge
    Research Article
  • eLife’s new Editor-in-Chief

    Timothy Behrens has been appointed Editor-in-Chief to lead our efforts to improve research communication for all.

    Press Pack

Latest research

    1. Neuroscience

    Transdiagnostic compulsivity is associated with reduced reminder setting, only partially attributable to overconfidence

    Annika Boldt, Celine A Fox ... Sam Gilbert
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    Annihilation of action potentials induces electrical coupling between neurons

    Moritz Schlötter, Georg Maret, Christoph J Kleineidam
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Decoding the physics of observed actions in the human brain

    Moritz F Wurm, Doruk Yiğit Erigüç
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI

    Joonas A Autio, Ikko Kimura ... Takuya Hayashi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Cortico-striatal action control inherent of opponent cognitive-motivational styles

    Cassandra Avila, Martin Sarter
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

    Franziska Auer, Katherine Nardone ... David Schoppik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Physics of Living Systems

    Probing the force-from-lipid mechanism with synthetic polymers

    Miranda L Jacobs, Jan Steinkühler ... Neha P Kamat
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Neuroscience

    Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks

    Bhanu Priya Somashekar, Upinder Singh Bhalla
    In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.
    1. Neuroscience

    A split-GAL4 driver line resource for Drosophila neuron types

    Geoffrey W Meissner, Allison Vannan ... FlyLight Project Team
    Thousands of cell-type-specific split-GAL4 driver lines and a massive, searchable image collection enable Drosophila neuroscientists to target neurons of interest with increased precision.