Papers by Feride Söylemez
Journal of Experimental and Clinical Medicine
Postpartum urinary retention (PUR) is defined as inability to void after six hours from delivery ... more Postpartum urinary retention (PUR) is defined as inability to void after six hours from delivery or having abnormal post-void residual volume after delivery (PVRV). Overt PUR is easily detectable condition but covert PUR usually remains undiagnosed. We aim to investigate the incidence of covert PUR and identify the risk factors. A retrospective analysis of the postpartum women was undertaken between January-July 2016. PVRV of the patients either delivered vaginally or cesarean section were assessed with ultrasound after first micturition. All the ultrasound scans were made by experienced gynecologist. PVRV of more than 150 mL was defined as covert PUR. Maternal age, parity, BMI, type of delivery, episiotomy, first urination time, fetal head circumference, labor augmentation and fetal birth weight were investigated as possible risk factors for covert PUR. The characteristics of the patients with or without covert PUR were compared. Of the 450 women included, 67 (17.49%) were diagnose...
Hypertension in Pregnancy, 2017
ABSTRACT The aim of this study is to compare ADAMTS (A Disintegrin and Metalloprotease Domains wi... more ABSTRACT The aim of this study is to compare ADAMTS (A Disintegrin and Metalloprotease Domains with Thrombospondins motifs) 1, 4, 12, and 13 levels in maternal and cord blood and placental tissue between preeclampsia and uncomplicated pregnancies. The enzyme-linked immunosorbent assay (ELISA) results showed that ADAMTS 1, 4, 12, and 13 levels in the maternal and cord blood were lower in the preeclampsia group than in the control group. Based on the immunohistochemistry (IHC) results, ADAMTS 1, 4, and 12 levels in placental tissues were higher in the preeclampsia group. According to the polymerase chain reaction (PCR) results, ADAMTS 1, 4, and 12 were higher, whereas ADAMTS 13 was lower in the preeclampsia group than in the control group.
Medical Network Klinik Bilimler ve Doktor, 2005
Journal of Obstetrics and Gynaecology Research, Nov 18, 2010
Squamous cell carcinoma arising from a mature cystic teratoma of the ovary is a rare event repres... more Squamous cell carcinoma arising from a mature cystic teratoma of the ovary is a rare event representing only 1-2% of all mature cystic teratomas. Furthermore, the synchronous occurrence of a second malignancy in this setting is extremely rare. A 63-year-old woman presented with a pelvic mass which was diagnosed as a left ovarian mature cystic teratoma preoperatively by ultrasonography. The frozen section of the mass revealed a left ovarian mature cystic teratoma with a focus of squamous cell carcinoma. Subsequently surgical staging procedure for ovarian cancer was performed. The final pathologic diagnosis was squamous cell carcinoma in mature cystic teratoma of the ovary, and synchronous endometrial adenocarcinoma with a mixture of endometrioid and mucinous subtypes as an incidental finding. The combination of these two synchronous cancers is unique and to the best of our knowledge, this has not been previously reported in the English language literature.
Turkiye Klinikleri Journal of Gynecology and Obstetrics, 1992
Cervical carcinoma was invesitgated for immunoreactivity of p-hCG. 25 patients with cervical canc... more Cervical carcinoma was invesitgated for immunoreactivity of p-hCG. 25 patients with cervical cancer in various stages were examined from this point of view. In this preliminary report the overall immunoreactivity of p-hCG was found to be 40 per cent. The values found were between 2 and 50 mill/ml and there was no significant correlation between age and the p-hCG values (r-0.3113, p>0.05). Additionally, results from the patients undergoing various treatment modalities were not differ from each other significantly (X 2 ~1.3972, 0.3>0.3>p>0.2).
Ultrasound in Obstetrics & Gynecology, Sep 30, 2019
done initially to assess fetal head position by palpating fetal spine and cephalic prominence, fo... more done initially to assess fetal head position by palpating fetal spine and cephalic prominence, followed by transvaginal digital examination after rupture of membranes fetal head position is determined after a uterine contraction, based on sagittal suture and posterior fontanelle. Then transabdominal ultrasound examination (also not during contraction) done using M Turbo Ultrasound System Fusifilm Sonosite to determine fetal head position. Ultrasonographic depiction of fetal head position was performed utilising midline intracranial structures (cavum septi pellucid, falx cerebri, thalami and cerebellar hemispheres), and anterior or posterior cranial structures (orbits, nasal bridge and cervical spine). fetal head position was classified as LOA, LOT, LOP, ROA, ROT, ROP. Person doing transvaginal digital examination was blinded from one doing transabdominal ultrasound. Results: The most frequently noted position was LOA (41%). In 78% (162/206) of fetal head positions determined by vaginal examination at <7 cms and 81% (63/77) at > 7 cms was consistent with those obtained by suprapubic transabdominal ultrasound (P = 0.02). Cohen's Kappa test of concordance indicated a good and excellent concordance of 0.70 (at <7 cms) and 0.86 (at > 7 cms). The rate of agreement between the two assessment methods for consultants versus residents was 80% versus 74% which was statistically significant (P = 0.01). Conclusions: The accuracy of transvaginal digital examination with transabdominal ultrasound was 78%, it was better by consultants than residents and also after 7 cms cervical dilatation. EP23.07 Ultrasound in labour to predict a need for emergency Caesarean section (ECS): a prospective, blinded cohort study
Journal of Maternal-fetal & Neonatal Medicine, Nov 13, 2019
Objective: To assess whether assessment with ultrasound could improve the detection of emergency ... more Objective: To assess whether assessment with ultrasound could improve the detection of emergency cesarean section (ECS) in laboring women. Methods: Women who presented with symptoms of active labor or women in need of labor induction were invited to participate in the study. Women included in the study were evaluated with ultrasonography for fetal biometry and vaginal examinations for Bishop score assessment. The main aim in this study was determining factors associated with ECS due to fetal distress and obstructed labor. Results: No fetal biometry variable was associated with ECS due to any indication (fetal distress and obstructed labor combined) in the univariate analysis. In multivariate analyses, biometry variables were adjusted for Bishop score at admission and only abdominal circumference percentile showed a significant association with the odds of ECS due to any indication (OR:1.02, 95% CI: 1.01-1.03). Biparietal diameter and abdominal circumference variables were associated with the odds of ECS due to obstructed labor in both univariate and multivariate analyses (p < .05 for all). However, the predictive accuracy of biparietal diameter percentile (area under the curve (AUC): 0.55, 95% CI: 0.46-0.63) and abdominal circumference percentile (AUC: 0.56, 95% CI: 0.48-0.64) without adjunct variables were poor. Moreover, the addition of fetal biometry parameters to Bishop score did not improve the predictive accuracy of Bishop score. Conclusion: Ultrasound assessment at admission, in addition to Bishop score assessment, did not significantly improve the prediction of ECS. Also, the fetal biometry alone had poor predictive capability for ECS. Routine ultrasound assessment at labor admission appears to be ineffective for predicting ECS. Precis Fetal biparietal diameter and abdominal circumference showed an association with emergency cesarean due to obstructed labor but the predictive accuracy of fetal biometry was low. Routine ultrasound examination at admission, in addition to Bishop score assessment, may not useful for assessing the risk of emergency section in unselected populations.
Frontiers in Pediatrics
Background:The umbilical cord blood contains a high concentration of stem cells. There is not any... more Background:The umbilical cord blood contains a high concentration of stem cells. There is not any published study evaluating the amount of stem cells that have the potential to be transferred to the infant through placental transfusion methods as delayed cord clamping (DCC) and umbilical cord milking (UCM). The aim of this study is to measure the concentrations of endothelial progenitor cell (EPC) and CD34+ hematopoietic stem cell (HSC) in the placental residual blood volume (PRBV), and evaluate the delivery room adaptation and cerebral oxygenation of these infants.MethodsInfants with ≥36 gestational weeks were randomized to receive DCC (120 s), UCM, or immediate cord clamping (ICC). EPC and CD34+ HSC were measured by flow cytometry from the cord blood. PRBV was collected in the setup. The cord blood gas analysis and complete blood count were performed. The heart rate (HR), oxygen saturation (SpO2), and cerebral regional oxygen saturation (crSO2) were recorded.ResultsA total of 103 ...
The Journal of Maternal-Fetal & Neonatal Medicine, 2020
Introduction: Preterm labor is the leading cause of premature mortality and morbidity. Therefore,... more Introduction: Preterm labor is the leading cause of premature mortality and morbidity. Therefore, to rule-in and rule-out preterm delivery is a very important issue in our clinical practice. Objective: The aim of this study was to investigate the value of placental alpha microglobulin-1 (PAMG-1) molecule positivity in cervicovaginal secretions of women who have a CL <25 mm and presenting with preterm labor symptoms to predict spontaneous preterm birth within seven days. Materials and methods: This was a prospective cohort study conducted in Ankara University Department of Obstetrics and Gynecology between August 2017 and February 2019 on the patients who had Preterm labor symptoms, <25 mm transvaginal cervical length (CL), clinically intact membranes. The primary outcome of the study was the power of CL and PAMG-1 positivity on the prediction of preterm birth in seven days. Results: Sensitivity and specificity values of PAMG-1 in our study population to predict spontaneous preterm birth in seven days were calculated 52.94% and 98.84%, respectively, negative predictive value (NPV) and positive predictive value (PPV) were calculated 91.4% and 90%, respectively. When we investigated our data according to different CL cutoffs, sensitivity and NPV for 20 mm cutoff were 88.24% and 96.3% that was better than PAMG-1, but specificity and PPV were 60.47% and 30.61%, respectively, that was more ineffective than PAMG-1. If we calculate the values according to 15 mm and 10 mm CL cutoffs sensitivity values were 58.8% and 23.53%, specificity values were 81.4% and 91.86%, NPV were 90.9% and 85.87%, PPV were 38.46% and 36.36%, respectively. Finally, accuracy value of PAMG-1 to predict spontaneous preterm birth in seven days was 91.26% that was better than other CL cutoffs (20 mm, 15 mm, and 10 mm). Conclusion: PAMG-1 molecule with high NPV and PPV (91.4% and 90%) combination will contribute our clinical decision on the population who had preterm labor symptoms and a CL shorter than 25 mm.
Journal of Trace Elements in Medicine and Biology, 2021
Journal of the Turkish-German Gynecological Association, Jun 9, 2016
The purpose of this case series is to provide preliminary evidence on the efficacy of pessary app... more The purpose of this case series is to provide preliminary evidence on the efficacy of pessary application in women with short cervix and at risk for preterm labor. Between May 2015 and July 2015, four pregnant women were followed-up with Arabin pessaries. The gestational age at the time of diagnosis was between the 23 th and 29 th weeks. Pessary application was associated with a prolongation of pregnancy lasting between 28 and 98 days. The gestational age at the time of delivery was between the 33rd and 39th weeks. Pessary use is non-invasive for the prolongation of pregnancy in pregnant women with shortened cervix. The major advantage of pessary use is its easy application without requiring anesthesia.
European Journal of Therapeutics
Mid pelvic forceps application, which may be used as alternative method to Cesarian sectio if the... more Mid pelvic forceps application, which may be used as alternative method to Cesarian sectio if there is no absolute cephalo-pelvic disproportion (CPD), are associated with second stage of labour abnormalities. Barton's forceps is American is orijin and appmied mora easily than otherb at midpelvic occiput transverse positions. İn our clinic, this forceps was used on 28 of 64 monitored, term pregnant women, who had fetal distress and prolonged labour. Other 36 patients with inadequate forceps conditions, underwent Cesarian sectio at the same period. Maternal and fetal outcomes were compared in the article.
International journal of hematology, 2014
The objective of this study was to investigate the determining effects of diagnosis time on pregn... more The objective of this study was to investigate the determining effects of diagnosis time on pregnancy outcomes in a population of pregnant women with idiopathic thrombocytopenic purpura (ITP). Records of all the pregnant women with thrombocytopenia were evaluated. Those with a confirmed diagnosis of ITP were included in the study. Main outcome measures were antenatal thrombocyte count, postpartum haemorrhage rate, and route of delivery. Foetal outcomes such as foetal thrombocyte count, haemorrhage, and birth weight were also reported as secondary outcome measures. Time of diagnosis either antenatal or preconception did not significantly alter the investigated parameters. Delivery route had no impact on complication rates. Time of diagnosis also did not affect treatment modality. ITP is rare disorder accounting for less than 5 % of all pregnant thrombocytopenias. Time of diagnosis does not affect maternal-foetal outcomes or treatment modality unless diagnosis is made during labour. C...
Turkiye Klinikleri Journal of Medical Sciences, 1991
Turkiye Klinikleri Journal of Gynecology and Obstetrics Special Topics, 2010
Turkiye Klinikleri Journal of Gynecology and Obstetrics Special Topics, 2008
The Journal of Trace Elements in Experimental Medicine, 1997
A case of coffee beans pica is reported that was associated with zinc deficiency and iron deficie... more A case of coffee beans pica is reported that was associated with zinc deficiency and iron deficiency anemia. Both deficiencies showed a good response to iron and zinc therapy.
The Journal of Maternal-Fetal & Neonatal Medicine, 2014
Abstract Objective: To investigate the association of perinatal risk factors including delivery m... more Abstract Objective: To investigate the association of perinatal risk factors including delivery mode with mortality in very low birthweight (VLBW) in a tertiary hospital setting. Methods: Medical records of 241 live-born VLBW infants (≤1500 g) were retrospectively reviewed. Details of maternal, obstetrical, perinatal risk factors and their associations with infant mortality were evaluated. Results: The overall infant mortality rate was 23.2%. Mortality was significantly higher for infants born at ≤27 gestational weeks and with a birthweight of ≤750 g (p = 0.000 and p = 0.000, respectively), showing a steep decrease thereafter. On ROC analysis, a cut off of 26.5 weeks was determined for mortality with a sensitivity of 57.1% and a specificity of 90.3% (area under the curve = 0.792, 95% CI: 0.719-0.866). On multivariate regression analysis, gestational week at birth, birthweight, antenatal steroid treatment and pathologic Doppler ultrasound findings were found as independent risk factors for mortality. Conclusions: Gestational week at birth, birthweight and antenatal steroid treatment remain the most important perinatal risk factors for infant mortality in VLBW infants. Mode of delivery does not seem to be associated with mortality when adjusted for other perinatal risk factors.
Journal of Obstetrics and Gynaecology, 2011
We evaluated the effect of closure or non-closure of parietal and visceral peritoneum during caes... more We evaluated the effect of closure or non-closure of parietal and visceral peritoneum during caesarean section (CS) on post-caesarean pain and analgesic requirement. A total of 94 primigravidas planned for elective CS were prospectively enrolled into closure (n = 46) and non-closure (n = 48) groups. Analgesia was provided by a patient-controlled analgesia pump (PCA) postoperatively. Pain was evaluated using a visual analogue scale (VAS) and verbal rating scale (VRS). Total dose of analgesics administered through PCA and times of analgesia demand and additional analgesics were also assessed. VAS and VRS scores were similar between the groups. The total dose of analgesics administered were similar (p = 0.095) between groups, however the mean number of analgesic demand (p = 0.020) and the additional analgesics (p &lt; 0.001) were higher in the closure group. As a conclusion, the closure or non-closure of the peritoneum does not have any impact on postoperative pain intensity, however the analgesia demand and additional analgesia requirement decreases with non-closure.
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Papers by Feride Söylemez