Papers by Gastone Celesia
Archives of Neurology, 1972
Page 1. Electroencephalographic Activation With Sleep and Methohexital Comparative Usefulness in ... more Page 1. Electroencephalographic Activation With Sleep and Methohexital Comparative Usefulness in the Diagnosis of Epilepsy Gastone G. Celesia, MD, and Richard E. Paulsen, MD, Madison, Wis Two types of electroencephalographic ...
Archives of Neurology, 1965
Oryx, 2014
The objective of this study is to estimate possible impacts of global climate change on the geogr... more The objective of this study is to estimate possible impacts of global climate change on the geographical distribution of the African lion Panthera leo in the coming decades. Current lion population occurrence data across Africa and distributions of lions in historical times (6,000-100 years before present) were obtained from the literature and integrated with data on present-day climates to generate ecological niche models. Models based on distributions of African lions were tested for predictive ability based on various subsetting approaches and were projected across Asia, Africa and Europe, to retrodict the distribution of the species for the past 6,000 years. These models were highly accurate, giving confidence in future projections. Future potential distributions were predicted by projecting ecological niche models onto three climate scenarios of future greenhouse gas emissions based on eight climate models for the years 2040-2070. The prediction was of relative range stability into the future: few new areas were identified as becoming suitable for the species but large areas of southern Africa and West Africa are expected to become less suitable. Predictions of effects of climate change on potential distributions of lions may assist conservation efforts by clarifying options for mitigation and response.
JAMA The Journal of the American Medical Association
Progressive left hemiparesis followed by face and trunk cutaneous vasodilation and hyperphagia de... more Progressive left hemiparesis followed by face and trunk cutaneous vasodilation and hyperphagia developed in a 28-year-old man. He began eating five to six meals a day and gained 16 kg in 60 days. Computed tomography disclosed a neoplastic lesion involving the midline via the hypothalamus and reaching the contralateral lenticular nucleus. Findings from endocrine studies, including thyroid-stimulating hormone, growth hormone, prolactin, and cortisol serum levels, were normal. Hyperphagia and consequent obesity were associated with bilateral destruction of the ventromedial hypothalamic area; cutaneous vasodilation was related to involvement of the preoptic area.
JAMA: The Journal of the American Medical Association, 1976
JAMA: The Journal of the American Medical Association, 1976
Among 60 cases of status epilepticus, there were 45 cases of convulsive status and 15 cases of no... more Among 60 cases of status epilepticus, there were 45 cases of convulsive status and 15 cases of nonconvulsive or confusional status. In 37 cases, status was due to an identifiable cause. The most frequent etiologic factors were vascular (nine cases), traumatic (seven cases), and metabolic (five cases). Four patients with metabolic encephalopathy had focal status. While the possibility of expanding lesions should be investigated in every case of convulsive status, a complete metabolic screening is also necessary. Non-convulsive status was represented by two cases of psychomotor status and 13 cases of absence status. Clinically, these cases were characterized by various impairments of intellectual functioning and confusion. Diagnosis was determined by characteristic changes in the electroencephalogram. Aggressive treatment is indicated by one or more of the major anticonvulsants, supplemented by adequate oxygenation and maintenance of biochemical homeostasis.
JAMA: The Journal of the American Medical Association, 1976
A 63-year-old man had severe thrombocytopenia after long-term levodopa therapy. Serologic studies... more A 63-year-old man had severe thrombocytopenia after long-term levodopa therapy. Serologic studies and clinical features indicate that the thrombocytopenia was due to an autoimmune process, presumably similar to that induced by the chemically similar drug methyldopa. Direct allergy to levodopa was ruled out by controlled challenge of the patient receiving levodopa. Combined levodopa-prednisone therapy was then instituted, with good clinical response and no recurrence of thrombocytopenia.
JAMA: The Journal of the American Medical Association, 1977
ABSTRACT
Supplements to Clinical Neurophysiology, 2000
Electroencephalography and Clinical Neurophysiology, 1985
Electroencephalography and Clinical Neurophysiology, 1989
This chapter discusses the role of clinical neurophysiology in the diagnosis and management of vi... more This chapter discusses the role of clinical neurophysiology in the diagnosis and management of visual disorders. The role of electroretinograms (ERG) is critical for evaluating widespread outer retinal disorders, can be used in predicting the onset of retinopathies in certain conditions such as diabetes and can be utilized to screen drugs with potential retinal toxicity. Electrophysiological methods are viable and the utilization of specific tests allows the precise localization of disorders affecting the photoreceptors, the macula, the outer retina, and the optic nerve. Neuroimaging is pivotal for the localization of the lesions within the visual pathways and often useful in the diagnosis of specific neurological diseases. It has an increasing role in the elucidation of human anatomy and physiopathology. The chapter shows that each method has specific indications as well as limitations and no method can assess vision. A battery of selected tests can only measure the complexities of visual perception.
Supplements to Clinical neurophysiology
Supplements to Clinical neurophysiology, 2006
Supplements to Clinical neurophysiology, 2006
The Journal of speech and hearing disorders, 1975
This report presents some of the underlying neuromuscular mechanisms of dysarthric speech product... more This report presents some of the underlying neuromuscular mechanisms of dysarthric speech production as they are manifested in selected individuals with parkinsonism. Earlier explanations of parkinsonian dysarthria emphasized that the balanced hypertonus of rigidity formed the basis of reduced range of movements in speech. The present data reveal two problems in the neuromuscular control signals that can result in a reduced range of speech movements in the absence of rigidity. These neuromuscular problems are described as acceleration and weakness. The implication of these findings for the evaluation and treatment of parkinsonian dysarthria is discussed.
Journal of Speech and Hearing Disorders, 1984
In this case study, a geriatric patient who had an 18-year history of hemifacial spasm was given ... more In this case study, a geriatric patient who had an 18-year history of hemifacial spasm was given EMG-biofeedback-assisted relaxation training. No formal speech therapy was provided. Our results confirmed two hypotheses: (a) The patient would learn to reduce frontalis EMG and facial spasm with and then without biofeedback, and (b) as a result, speech would be markedly improved. At both the 1-month and 15-month follow-up the patient retained the ability to relax his facial muscles with similar carry-over to speech. Possible neurophysiologic mechanisms of action mediating the feedback training are discussed.
Journal of the History of the Neurosciences, 2012
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Papers by Gastone Celesia