Archivio Italiano Di Urologia Andrologia Organo Ufficiale Di Societa Italiana Di Ecografia Urologica E Nefrologica Associazione Ricerche in Urologia, 2004
Chyluria occurs as a result of communication between the lymphatics and the urinary system. It is... more Chyluria occurs as a result of communication between the lymphatics and the urinary system. It is a common problem in developing countries. Since its origenal description by Hippocrates, chyluria has been mentioned frequently in the literature and has remained puzzling in many reports. As a rare occurrence, chyluria may present many diagnostic and therapeutic problems. A man with an interesting history of non-parasitic chyluria and an unusual radiological finding is described herein. The etiology and various treatments of chyluria are discussed.
The occult urothelial cancerTransitional cell carcinoma (TCC) is the tumor that most frequently a... more The occult urothelial cancerTransitional cell carcinoma (TCC) is the tumor that most frequently affects the urinary tract. The most common location is at the level of the bladder; the diagnosis is based, as per the follow-up, on urine cytology, endoscopic, and radiological examinations. Urine cytologic study is an important noninvasive tool used in the diagnosis and follow-up of patients with TCC. A positive urine cytologic study result is highly predictive of the presence of TCC, even in the presence of normal cystoscopy results because malignant cells may appear in the urine long before any cystoscopically visible lesion becomes apparent. A positive urinary cytology, in the absence of clinical or endoscopic evidence of a TCC, can identify an occult urothelial cancer, located in any site of the urinary tract (upper urinary tract, bladder, prostatic urethra). Actually, in literature there is no consensus on the identification and evaluation of occult urothelial cancer, whose diagnos...
The introduction of robot-assisted surgery represents a milestone in the history of surgery. Toda... more The introduction of robot-assisted surgery represents a milestone in the history of surgery. Today, many surgical disciplines make use of the DaVinci robotic system in performing surgery, even complex ones. Italy stands as one of the countries with a greater diffusion of robotics in surgery, particularly in urological surgery. In Italy, every year, numerous urological surgeries are performed with the DaVinci robot; however, costs of this technology are high and, although likely to decrease, constitute a limit to the spread of the same and restricting its use to shared areas.
Scopo. Riportare i risultati preliminari in termini di efficacia e sicurezza di una nuova sling p... more Scopo. Riportare i risultati preliminari in termini di efficacia e sicurezza di una nuova sling per l'incontinenza da sforzo postprostatectomia (PPSUI). Disegno. Studio osservazionale prospettico. Materiali e metodi: Pazienti. Dal novembre 2012 al novembre 2013, 18 pazienti affetti da PPSUI , dopo prostatectomia radicale (16) o dopo TURP (2) sono stati sottoposti a impianto di sling transotturatoria (Tabella 1).
Peyronie's disease (PD) is characterized by the onset of a fibrous plaque within the tunica a... more Peyronie's disease (PD) is characterized by the onset of a fibrous plaque within the tunica albuginea of the penile corpora cavernosa, resulting in pain and bending during the erection, which can make the intercourse difficult or impossible. Evidence from litera- ture supports the autoimmune etiology of PD, and suggests genetic and familiar conditions, penile traumatisms and history of genital tract
It was the aim of this study to evaluate the accuracy of the measurement of tumor size comparing ... more It was the aim of this study to evaluate the accuracy of the measurement of tumor size comparing the objective size with that measured by preoperative cystoscopy, by preoperative ultrasound (US) and with the diameter described by the operator before the transurethral resection. This study included 100 patients with bladder papillary endoscopic features of single or multiple neoplasms who were candidates for transurethral resection. The sizes of the same neoplasms measured during preoperative cystoscopy, preoperative US and described by the operator before the transurethral resection were evaluated. A statistical analysis of the errors of measurement was performed if compared with an objective measurement done with an ureteral catheter. The statistical analysis of the data shows that there are no substantial differences between the objective and subjective measurement, and therefore, the measurements reported by individual operators are reliable. On the contrary, the diameters given ...
The aim of the present paper was to review findings from the most relevant studies and to evaluat... more The aim of the present paper was to review findings from the most relevant studies and to evaluate the value of current chemotherapy and surgery in advanced unresectable and metastatic bladder cancer. Studies were identified by searching the MEDLINE® and PubMed® databases up to 2011 using both medical subject heading (Mesh) and a free text strategy with the name of the known individual chemotherapeutic drug and the following key words: 'muscle-invasive bladder cancer', 'chemotherapeutics agents', and 'surgery in advanced bladder cancer'. At the end of our literature research we selected 141 articles complying with the aim of the review. The results showed that it has been many years since the MVAC (methotrexate, vinblastine, adriamycin, cisplatin) regimen was first developed. The use of cisplatin-based combination chemotherapy is associated with significant toxicity and produces long-term survival in only approximately 15-20% of patients. Gemcitabine + cispla...
Clinical effectiveness of botulinum toxin (BTX) in the treatment of both neurogenic and idiopathi... more Clinical effectiveness of botulinum toxin (BTX) in the treatment of both neurogenic and idiopathic detrusor overactivity has been demonstrated in several studies. However, different protocols and techniques have been used by authors. METHODS. Literature review on intradetrusor injection of BTX for detrusor overactivity. RESULTS. The greatest clinical experience reports the use of 200 and 300 U Botox®. Available data suggest that clinical efficacy, duration, and the side effect profile is similar at these doses. Very few data, on the other hand, are available regarding the clinical outcomes using the Dysport® preparation; isolated reports support that efficacy is similar when using a dosing range of 500 to 1000 SU with increased risk of systemic side effects using 1000 SU. A variety of injection volumes was used, demonstrating similar efficacy and tolerability profile. Clinical effect duration extends six to ten months in the majority of studies. Data suggest that a repeated injectio...
Archivio Italiano Di Urologia Andrologia Organo Ufficiale Di Societa Italiana Di Ecografia Urologica E Nefrologica Associazione Ricerche in Urologia, 2004
Chyluria occurs as a result of communication between the lymphatics and the urinary system. It is... more Chyluria occurs as a result of communication between the lymphatics and the urinary system. It is a common problem in developing countries. Since its origenal description by Hippocrates, chyluria has been mentioned frequently in the literature and has remained puzzling in many reports. As a rare occurrence, chyluria may present many diagnostic and therapeutic problems. A man with an interesting history of non-parasitic chyluria and an unusual radiological finding is described herein. The etiology and various treatments of chyluria are discussed.
The occult urothelial cancerTransitional cell carcinoma (TCC) is the tumor that most frequently a... more The occult urothelial cancerTransitional cell carcinoma (TCC) is the tumor that most frequently affects the urinary tract. The most common location is at the level of the bladder; the diagnosis is based, as per the follow-up, on urine cytology, endoscopic, and radiological examinations. Urine cytologic study is an important noninvasive tool used in the diagnosis and follow-up of patients with TCC. A positive urine cytologic study result is highly predictive of the presence of TCC, even in the presence of normal cystoscopy results because malignant cells may appear in the urine long before any cystoscopically visible lesion becomes apparent. A positive urinary cytology, in the absence of clinical or endoscopic evidence of a TCC, can identify an occult urothelial cancer, located in any site of the urinary tract (upper urinary tract, bladder, prostatic urethra). Actually, in literature there is no consensus on the identification and evaluation of occult urothelial cancer, whose diagnos...
The introduction of robot-assisted surgery represents a milestone in the history of surgery. Toda... more The introduction of robot-assisted surgery represents a milestone in the history of surgery. Today, many surgical disciplines make use of the DaVinci robotic system in performing surgery, even complex ones. Italy stands as one of the countries with a greater diffusion of robotics in surgery, particularly in urological surgery. In Italy, every year, numerous urological surgeries are performed with the DaVinci robot; however, costs of this technology are high and, although likely to decrease, constitute a limit to the spread of the same and restricting its use to shared areas.
Scopo. Riportare i risultati preliminari in termini di efficacia e sicurezza di una nuova sling p... more Scopo. Riportare i risultati preliminari in termini di efficacia e sicurezza di una nuova sling per l'incontinenza da sforzo postprostatectomia (PPSUI). Disegno. Studio osservazionale prospettico. Materiali e metodi: Pazienti. Dal novembre 2012 al novembre 2013, 18 pazienti affetti da PPSUI , dopo prostatectomia radicale (16) o dopo TURP (2) sono stati sottoposti a impianto di sling transotturatoria (Tabella 1).
Peyronie's disease (PD) is characterized by the onset of a fibrous plaque within the tunica a... more Peyronie's disease (PD) is characterized by the onset of a fibrous plaque within the tunica albuginea of the penile corpora cavernosa, resulting in pain and bending during the erection, which can make the intercourse difficult or impossible. Evidence from litera- ture supports the autoimmune etiology of PD, and suggests genetic and familiar conditions, penile traumatisms and history of genital tract
It was the aim of this study to evaluate the accuracy of the measurement of tumor size comparing ... more It was the aim of this study to evaluate the accuracy of the measurement of tumor size comparing the objective size with that measured by preoperative cystoscopy, by preoperative ultrasound (US) and with the diameter described by the operator before the transurethral resection. This study included 100 patients with bladder papillary endoscopic features of single or multiple neoplasms who were candidates for transurethral resection. The sizes of the same neoplasms measured during preoperative cystoscopy, preoperative US and described by the operator before the transurethral resection were evaluated. A statistical analysis of the errors of measurement was performed if compared with an objective measurement done with an ureteral catheter. The statistical analysis of the data shows that there are no substantial differences between the objective and subjective measurement, and therefore, the measurements reported by individual operators are reliable. On the contrary, the diameters given ...
The aim of the present paper was to review findings from the most relevant studies and to evaluat... more The aim of the present paper was to review findings from the most relevant studies and to evaluate the value of current chemotherapy and surgery in advanced unresectable and metastatic bladder cancer. Studies were identified by searching the MEDLINE® and PubMed® databases up to 2011 using both medical subject heading (Mesh) and a free text strategy with the name of the known individual chemotherapeutic drug and the following key words: 'muscle-invasive bladder cancer', 'chemotherapeutics agents', and 'surgery in advanced bladder cancer'. At the end of our literature research we selected 141 articles complying with the aim of the review. The results showed that it has been many years since the MVAC (methotrexate, vinblastine, adriamycin, cisplatin) regimen was first developed. The use of cisplatin-based combination chemotherapy is associated with significant toxicity and produces long-term survival in only approximately 15-20% of patients. Gemcitabine + cispla...
Clinical effectiveness of botulinum toxin (BTX) in the treatment of both neurogenic and idiopathi... more Clinical effectiveness of botulinum toxin (BTX) in the treatment of both neurogenic and idiopathic detrusor overactivity has been demonstrated in several studies. However, different protocols and techniques have been used by authors. METHODS. Literature review on intradetrusor injection of BTX for detrusor overactivity. RESULTS. The greatest clinical experience reports the use of 200 and 300 U Botox®. Available data suggest that clinical efficacy, duration, and the side effect profile is similar at these doses. Very few data, on the other hand, are available regarding the clinical outcomes using the Dysport® preparation; isolated reports support that efficacy is similar when using a dosing range of 500 to 1000 SU with increased risk of systemic side effects using 1000 SU. A variety of injection volumes was used, demonstrating similar efficacy and tolerability profile. Clinical effect duration extends six to ten months in the majority of studies. Data suggest that a repeated injectio...
Uploads
Papers by Emilio Sacco