• 14 December 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of the human detection of influenza A(H5N1) virus, one case, in Louisiana, United States, Louisiana in an individual aged ≥18 years which presented severe symptoms. The patient was hospitalized in an intensive care unit. This is the first case reported in Louisiana: CDC.
• 6 December 2024: FAO alert on avian influenza - Risk of upsurge and regional spread through wild birds in Latin America and the Caribbean: https://openknowledge.fao.org.
• 3 December 2024: Eleventh PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Avian influenza A(H5N1) in the Americas Region: https://www.paho.org/en/documents/epidemiological-alert-human-cases-avian-influenza-ah5n1-americas-region-3-december-2024.
• 29 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional confirmed cases of influenza A(H5) in California, both developed symptoms while working at a commercial dairy cattle farm where cows were presumed to be infected with Influenza A(H5N1) virus.
• 24 November 2024: California Department of Public Health, Office of Communications publishes: California Acts to Protect Public Health: CDPH Warns Against Drinking Single Lot of Raw Milk Following Bird Flu Detection; Secures Voluntary Recall, no illnesses have been reported; Pasteurized milk is safe to drink. Source: cdph.ca.
• 23 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional confirmed cases of influenza A(H5) in California, including the first case identified in a child in the United States, with unknown exposure, the other case is ≥18 years of age who developed symptoms while working at a commercial dairy cattle farm where cows are presumed to be infected with Influenza A(H5N1).
• 18 November 2024: Tenth PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Alert - Avian influenza A(H5N1) in the Americas Region: PAHO.
• 16 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of one additional confirmed case in California of influenza A(H5), a patient who developed symptoms while working at a commercial dairy cattle farm where cows were presumed to be infected with influenza A(H5N1). This represents the 27th case in California.
• 15 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of six additional confirmed cases of influenza A(H5), five in California and one in Oregon. The five cases reported in California had developed symptoms while working at commercial dairy cattle farms, where cows are presumed to be infected with Influenza A(H5N1); these represent the 22nd, 23rd, 24th, 25th and 26th cases in California. The case in Oregon developed illness performing decontamination operations at a facility where HPAI A(H5N1) in poultry was detected. This case represents the first case reported in Oregon.
• 14 November 2024: The Canada IHR National Focal Point (NFP) reported to PAHO/WHO a confirmed human case of avian influenza A(H5N1) detected in the province of British Columbia (B.C), representing the first case detected in Canada.
• 7 November 2024: PAHO published the Public health risk assessment associated with the potential occurrence of zoonotic avian influenza A(H5N1) clade 2.3.4.4b in Latin-American and the Caribbean. The overall risk in the Americas Region, especially in Latin-American and the Caribbean was classified as "Moderate" with a "Moderate" level of confidence with the available information: PAHO.
• 6 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional cases of  influenza A(H5), one in the state of Washington who developed symptoms while performing depopulation operations at a facility where HPAI A(H5N1) has been detected in poultry and the other in California who developed symptoms  while working at a commercial dairy farm where cows were presumed infected with influenza A(H5N1).
• 2 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of three additional Influenza A(H5) cases in California, United States; they developed symptoms while working at commercial dairy cattle farms where avian influenza A(H5N1) virus was detected in cows.
• 1 November 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of one additional influenza A(H5) virus human case in California, United States. This patient developed illness while working at a commercial dairy cattle farm where avian influenza A(H5N1) virus had been detected in cows. This is the seventeenth confirmed case in California.
• 31 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of four additional Influenza A(H5N1) human cases in Washington, United States. All of them exposed to highly pathogenic avian influenza (HPAI) A(H5N1) while performing disposal and depopulation operations at a poultry facility in Washington.
• 26 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional confirmed cases of influenza A(H5), one in the state of Washington and the other in the state of California. The case in Washington developed illness while performing disposal and depopulation operations at a facility where HPAI A(H5N1) virus was detected in poultry and the case in California developed illness while working at a cattle farm where influenza A(H5N1) had been detected in cows. These represent the 6th confirmed case in Washington and the 16th in California.
• 25 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of three additional confirmed cases of influenza A(H5) in the state of Washington, United States, all developed illness while performing disposal and depopulation operations at a facility where HPAI A(H5N1) virus clade 2.3.4.4b, was detected in poultry. These are the 3rd, 4th, 5th confirmed human cases in Washington state.
• 24 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two confirmed cases of influenza A(H5) in the state of Washington, United States, both developed illness while performing disposal and depopulation operations at a facility where HPAI A(H5N1) virus clade 2.3.4.4b, genotype D1.1, was detected in poultry. These were the first two cases in Washington, all occurring after exposure to infected poultry.
• 24 October 2024: First detection of influenza A(H5N1) among bovines in the state of Utah, United States. Source: WAHIS.
• 23 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional confirmed cases of influenza A(H5) in the state of California, both developed symptoms while working at different commercial farms where influenza A(H5N1) virus had been detected in cows. These are the 14th and 15th cases in California, all occurring after exposure to infected dairy cattle.
• 19 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional confirmed cases of influenza A(H5) in California, United States, both developed illness while working at different commercial dairy cattle farms where influenza A(H5N1) virus has been detected in cows. These represent the 12th and 13th cases detected in California.
• 17 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of one additional case of influenza A(H5) in California, United States, in a person who developed illness while working at a commercial dairy cattle farm where influenza A(H5N1) virus had been detected in cows. This represents the 11th case in California.
• 16 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of four additional confirmed cases of influenza A(H5) in California, all of which developed symptoms while working on different commercial dairy cattle farms where A(H5N1) was detected.
• 11 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of two additional human cases of influenza A(H5) virus in California, who developed symptoms after working on commercial dairy cattle farms where A(H5N1) virus had been detected in cows.
• 10 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of an additional human case of influenza A(H5) virus in California, in a person who worked at a commercial dairy cattle farm where influenza A(H5N1) virus had been detected in cows. This represents the fourth confirmed case in California.
• 9 October 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of an additional human case of influenza A(H5) virus in California, in a person who developed symptoms while working at a commercial dairy cattle farm where influenza A(H5N1) virus had been detected in cows.
• 8 October 2024: Ninth PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Alert -Human infections caused by avian influenza A(H5N1) in the Americas Region: PAHO.
• 4 October 2024: United States IHR National Focal Point (NFP) notification of human detection of influenza A(H5) virus (2 cases) in California, United States, both worked in a dairy farm where influenza A(H5N1) had been detected in cattle; no known link between the cases. 

• 22 July 2024: United States IHR National Focal Point (NFP) notification of two additional confirmed influenza A(H5) human cases in Colorado, United States, who had performed disposal and culling operations prior to symptom onset at a facility where four previous human infections of HPA) A(H5N1) had been identified, and where HPAI A(H5N1) virus clade 2.3.4.4b, genotype B3.13 was detected in poultry.
• 15 July 2024: United States IHR National Focal Point (NFP) notification of human detection of influenza A(H5) virus (4 cases) in Colorado, United States, linked to poultry farm where HPAI A(H5N1) virus clade 2.2.4.4b, genotype B3.13 had been detected in poultry.
• 13 July 2024: PAHO published the Public Health Risk Assessment associated with the spread of zoonotic avian influenza A(H5N1) clade 2.3.4.4b in the Region of the Americas - 12 July 2024: PAHO.
• 3 July 2024: The United States IHR National Focal Point (NFP) notified PAHO/WHO of human detection of influenza A (H5N1) virus in Colorado, United States, in a worker at a commercial dairy cattle farm where influenza A(H5N1) virus had been detected in cows. 

• 30 May 2024: The United States IHR National Focal Point notified PAHO/WHO of the human detection of influenza A(H5N1) virus in Michigan, United States, in another worker at commercial dairy cattle farm where A(H5N1) virus had been detected in cows. Representing the third human case in the U.S. in 2024 (TX n=1, MI n=2) and fourth overall. Michigan Health & Human Services, Additional influenza A (H5) case detected in Michigan. Source: Michigan.gov/mdhhs. CDC Confirms Second Human Influenza A(H5) avian Flu Case in Michigan; Third Case Tied to Dairy Outbreak: CDC.
• 25 May 2024: First detection of influenza A(H5N1) among bovines in the states of Minnesota and Wyoming, United States. Source: WAHIS.
• 23 May 2024: The United States IHR National Focal Point notified PAHO/WHO of the human detection of influenza A(H5N1) virus in Michigan, United States, in a worker at commercial dairy cattle farm where A(H5N1) virus had been detected in cows. Representing the second human case in the U.S. in 2024.
• 26 April 2024: Publication of the: Joint FAO/WHO/WOAH preliminary assessment of recent influenza A(H5N1) viruses, as of 23 April 2024: WHO.
• 21 April 2024: First detection of influenza A(H5N1) among bovines in the state of Colorado, United States. Source: WAHIS.
• 19 April 2024: First detection of influenza A(H5N1) among bovines in the state of Oklahoma, United States. Source: WAHIS.
• 9 April 2024: Information on the first case of avian influenza A(H5) in the United States in 2024, second case since 2022, was published by WHO via Disease Outbreak News (DON): WHO.
• 4 April 2024: First detection of influenza A(H5N1) among bovines in the state of North Carolina, United States. Source: WAHIS.
• 1 April 2024: The United States IHR National Focal Point (NFP) notified the detection of influenza A(H5N1) virus in a human case in Texas, in a worker of a commercial dairy cattle farm where influenza A(H5N1) virus had been recently detected in dairy cattle. Representing the first human case in the United States in 2024, and second overall case.

• 22 March 2024: Seventh PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Update - Outbreaks of avian influenza caused by influenza A(H5N1) in the Region of the Americas: PAHO.
• 20 March 2024: First detection of influenza A(H5N1) among bovines in the states of Kansas and Michigan, United States. Source: WAHIS.
• 16 March 2024: First detection of influenza A(H5N1) among bovines in the state of New Mexico, United States. Source: WAHIS.
• 13 March 2024: First detection of influenza A(H5N1) among bovines in the states of Idaho, United States. Source: WAHIS.
• 10 March 2024: First detection of influenza A(H5N1) among bovines in the state of Texas, United States. Source: WAHIS.
• 14 January 2024: Detection of influenza A(H5N1) among bovines in the state of California, United States, representing first detection in 2024 among bovines and the fourth detection in California, United States since 2020. Source: Source: WAHIS.

• 18 May 2023: Fifth PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Update - Outbreaks of avian influenza caused by influenza A(H5N1) in the Region of the Americas: https://www.paho.org/en/documents/epidemiological-update-outbreaks-avian-influenza-caused-influenza-ah5n1-region-americas.
• 31 March 2023: PAHO/WHO published the Briefing Note: Human infection caused by avian influenza A(H5) virus in Chile: https://www.paho.org/en/documents/briefing-note-human-infection-caused-avian-influenza-ah5-virus-chile-31-march-2023.
• 29 March 2023: First detection of influenza A(H5N1) among bovines in the states of Texas, United States. Source: WAHIS.
• 20 March 2023: First detection of influenza A(H5N1) among domestic mammals in Canada. Source: WAHIS.
• 13 March 2023: Fourth PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Alert - Outbreaks of avian influenza caused by influenza A(H5N1) in the Region of the Americas: https://www.paho.org/en/documents/epidemiological-alert-outbreaks-avian-influenza-caused-influenza-ah5n1-region-americas.
• 18 January 2023: Information on the first case of avian influenza A(H5) in Ecuador was published by WHO via Disease Outbreak News (DON). https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON434.
• 11 January 2023: Third PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Update - Outbreaks of avian influenza and public health implications in the Region of the Americas: https://www.paho.org/en/documents/epidemiological-update-outbreaks-avian-influenza-and-public-health-implications-region-0 .
• 9 January 2023: The Ecuador International Health Regulations (IHR) National Focal Point (NFP) notified the first human case of avian influenza A(H5) to PAHO/WHO, representing the first case in Ecuador and second in the Americas Region.

• 19 November 2022: First PAHO/WHO Epidemiological Alert on Avian Influenza A(H5N1): Epidemiological Alert - Outbreaks of avian influenza and public health implications in the Region of the Americas: https://www.paho.org/en/documents/epidemiological-alert-outbreaks-avian-influenza-and-public-health-implications-region.
• 12 November 2022: First detection of influenza A(H5N1) among domestic mammals in the United States. Source: WAHIS.
• 6 May 2022: Information on the first case of avian influenza A(H5) in the United States published by WHO via Disease Outbreak News (DON). https://www.who.int/emergencies/disease-outbreak-news/item/2022-E000111.
• 29 April 2022: The United States International Health Regulations (IHR) National Focal Point (NFP) notified the first human case of avian influenza A(H5) to PAHO/WHO in Colorado, in a poultry farm worker where influenza A(H5N1) virus was confirmed in poultry.
• 3 April 2022: First detection of influenza A(H5N1) among wild mammals in Canada. Source: WAHIS.
• 30 March 2022: First detection of influenza A(H5N1) among wild mammals in the United States. Source: WAHIS.
• 9 February 2022: United States Department of Agriculture APHIS confirmed the first outbreak of HPAI A(H5N1) virus in a commercial turkey flock in Indiana. Source: USDA Confirms HPAI in a Commercial Turkey Flock in Dubois County, Indiana (webinar, 2/09/2022).
• 7 February 2022: First detection of influenza A(H5N1) among domestic birds in the United States. Source: WAHIS.

    2021

• 30 December 2021: First detection of influenza A(H5N1) among wild birds in the United States. Source: WAHIS.
• 9 December 2021: First detection of influenza A(H5N1) among domestic birds in Canada. Source: WAHIS.
• 26 November 2021: First detection of influenza A(H5N1) among wild birds in Canada. Source: WAHIS.

    2020

• 10 November 2020: Influenza A(H5N1) was detected in bovines in the state of California, United States. Source: WAHIS.
• 28 October 2020: Influenza A(H5N1) was first detected in bovines in the state of California, United States of America. Source: WAHIS