Isoaminile

Isoaminile
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R05DB04 (WHO) ;
Identifiers
	IUPAC name 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile;
CAS Number	77-51-0 ;
PubChem CID	6481;
DrugBank	DB08944 ;
ChemSpider	6236 ;
UNII	R4823W2PQL;
KEGG	D08088 ;
CompTox Dashboard (EPA)	DTXSID5057830 ;
ECHA InfoCard	100.000.940
Chemical and physical data
Formula	C16H24N2
Molar mass	244.382 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C;
	InChI InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3 ; Key:WFLSCFISQHLEED-UHFFFAOYSA-N ;
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Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.^[1]

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period.^[1] In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.^[1]

References

^ ^a ^b ^c Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. PMID 14146305. Retrieved 2013-09-12.

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[R1-1] Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. PMID 14146305. Retrieved 2013-09-12.

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References

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