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Musca domestica Implicated in the Ecology of the Extended-spectrum Beta-lactamase-producing Escherichia coli (ESBL-EC)

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Abstract

Purpose of Review

Livestock remains one of the main protein sources, but at the same time, it is one of the sources of antimicrobial-resistant bacteria. The same bacteria have found an ecological niche in the livestock establishment.

Recent Findings

Musca domestica (fly) inhabits the same niche and will interact with livestock, exposing themselves to these bacteria. Escherichia coli, producing extended-spectrum beta-lactamases, is an organism resistant to oximino-cephalosporins and monobactams, which can compromise the lives of humans. Musca domestica is a vector that contributes to the transport and dispersion of resistant bacteria.

Summary

All these components justify an epidemiological intervention, where M. domestica could reveal the phenotypic and genotypic profile of antimicrobial resistance of E. coli and other microorganisms of clinical importance for humans and farm animals. This article highlights the conditions and factors that drive the ecology of resistance antimicrobials, E. coli and M. domestica, within the One Health approach.

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Data Availability

No datasets were generated or analysed during the current study.

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Acknowledgements

Special thanks to Yaoyao Zhou, RN, for interpreting and translating this manuscript.

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Authors and Affiliations

  1. Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA

    Rojelio Mejia

  2. Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine and Zootechnics, Universidad Nacional Hermilio Valdizan, Huánuco, Peru

    Carlos Alberto Pineda Castillo

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  1. Rojelio Mejia
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RM and CP wrote, edited, and prepared figures and tables. All authors reviewed the manuscript.

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Correspondence to Carlos Alberto Pineda Castillo.

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Rojelio Mejia is the current Co-Editor-in-Chief of Current Tropical Medicine Reports.

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Mejia, R., Castillo, C.A.P. Musca domestica Implicated in the Ecology of the Extended-spectrum Beta-lactamase-producing Escherichia coli (ESBL-EC). Curr Trop Med Rep 11, 179–186 (2024). https://doi.org/10.1007/s40475-024-00328-w

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