TUBG2

Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.

TUBG2
Identifiers
Aliases	TUBG2, tubulin gamma 2
External IDs	OMIM: 605785; MGI: 2144208; HomoloGene: 69216; GeneCards: TUBG2; OMA:TUBG2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.2 Start 42,659,284 bp End 42,667,006 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 D Start 101,046,733 bp End 101,052,613 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right frontal lobe right hemisphere of cerebellum anterior cingulate cortex prefrontal cortex body of pancreas Amygdala Brodmann area 9 C1 segment nucleus accumbens caudate nucleus Top expressed in zygote secondary oocyte primary oocyte incisor superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex dorsomedial hypothalamic nucleus superior colliculus neural layer of retina More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding structural molecule activity GTPase activity structural constituent of cytoskeleton Cellular component cytoplasm microtubule cytoskeleton microtubule organizing center cytoplasmic microtubule cytosol centrosome spindle microtubule gamma-tubulin complex pericentriolar material cytoskeleton microtubule nucleus spindle Biological process cytoplasmic microtubule organization microtubule nucleation microtubule-based process mitotic sister chromatid segregation meiotic spindle organization microtubule cytoskeleton organization mitotic cell cycle mitotic spindle organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27175 103768 Ensembl ENSG00000037042 ENSMUSG00000045007 UniProt Q9NRH3 Q8VCK3 RefSeq (mRNA) NM_016437 NM_001320509 NM_134028 RefSeq (protein) NP_001307438 NP_057521 NP_598789 Location (UCSC) Chr 17: 42.66 – 42.67 Mb Chr 11: 101.05 – 101.05 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Tassin AM, Celati C, Moudjou M, Bornens M (1998). "Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin". J. Cell Biol. 141 (3): 689–701. doi:10.1083/jcb.141.3.689. PMC 2132749. PMID 9566969.
• Herreros L, Rodríguez-Fernandez JL, Brown MC, et al. (2000). "Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton". J. Biol. Chem. 275 (34): 26436–40. doi:10.1074/jbc.M003970200. hdl:10261/135387. PMID 10840040.
• Wise DO, Krahe R, Oakley BR (2000). "The gamma-tubulin gene family in humans". Genomics. 67 (2): 164–70. doi:10.1006/geno.2000.6247. PMID 10903841.
• Niwa J, Ishigaki S, Doyu M, et al. (2001). "A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity". Biochem. Biophys. Res. Commun. 281 (3): 706–13. doi:10.1006/bbrc.2001.4414. PMID 11237715.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Chang F, Re F, Sebastian S, et al. (2004). "HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes". Mol. Biol. Cell. 15 (4): 1793–801. doi:10.1091/mbc.E03-09-0691. PMC 379276. PMID 14767062.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.