Arylalkylamine
Substituted arylalkylamines, also alternatively known in many cases as substituted arylethylamines,[1] are a group of chemical compounds.[2][3][4] These compounds are divided into two main categories: indolylalkylamines and phenylalkylamines.[2]
- Indolylalkylamines include substances like tryptamines, which are found in some natural compounds and can affect mood and perception.[2]
- Phenylalkylamines include substances like phenethylamines and amphetamines, which are found in both natural and synthetic forms.[2]
These compounds are related to monoamine neurotransmitters, which are chemicals in the brain that transmit signals between nerve cells. Because of this, substituted arylalkylamines can have a wide range of effects on the body and mind. They are used in many medications, including:
- Psychostimulants, which increase alertness and energy.
- Anorectics, which suppress appetite.
- Wakefulness-promoting agents, which help people stay awake.
- Bronchodilators, which make breathing easier.
- Decongestants, which relieve nasal congestion.
- Antidepressants, which are used to treat depression.
- Entactogens, which enhance feelings of emotional closeness.
- Psychedelics, which alter perception and consciousness.
See also
[edit]References
[edit]- ^ Freeman S, Alder JF (July 2002). "Arylethylamine psychotropic recreational drugs: a chemical perspective". Eur J Med Chem. 37 (7): 527–539. doi:10.1016/s0223-5234(02)01382-x. PMID 12126772.
- ^ a b c d Glennon RA (October 1999). "Arylalkylamine drugs of abuse: an overview of drug discrimination studies". Pharmacol. Biochem. Behav. 64 (2): 251–256. doi:10.1016/S0091-3057(99)00045-3. PMID 10515299. S2CID 10221368.
- ^ Richard K. Ries; Shannon C. Miller; David A. Fiellin (2009). Principles of Addiction Medicine. Lippincott Williams & Wilkins. pp. 245–. ISBN 978-0-7817-7477-2.
- ^ Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 639–. ISBN 978-1-60913-345-0.
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