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Trimetozine

From Wikipedia, the free encyclopedia
Trimetozine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • Morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.010.215 Edit this at Wikidata
Chemical and physical data
FormulaC14H19NO5
Molar mass281.308 g·mol−1
3D model (JSmol)
  • COC1=CC(=CC(=C1OC)OC)C(=O)N2CCOCC2

Trimetozine (Opalene, Trimolide, Trioxazine) is a sedative that has been marketed in Europe since 1959.[1][2] It also has mild tranquilizing effects and has been used in the treatment of anxiety.[3][4] Its mechanism of action is unclear.[citation needed]

Conversion of the amide in trimetozine to the thioamide gives Tritiozine.

References

[edit]
  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 1932. ISBN 3-88763-075-0.
  2. ^ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9.
  3. ^ Taverna P, Ferrari G (June 1970). "[Clinical trial of a new tranquilizing agent: trioxazine]". Minerva Medica (in Italian). 61 (46): 2574–90. PMID 5425739.
  4. ^ Shpak VM, Shcheglova AI (August 1968). "[Trioxazine in the treatment of night anxiety in children]". Pediatriia (in Russian). 47 (8): 76–7. PMID 5730033.
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