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Cryo-forum

A Framework for Orientation Recovery with Uncertainty Measurement in Cryo-EM Image Analysis

Cryo-forum is a framework designed to facilitate experimentation with various strategies for orientation recovery in cryo-electron microscopy (cryo-EM).

Manuscript

  • Cryo-forum: A Framework for Orientation Recovery with Uncertainty Measurement in Cryo-EM Image Analysis

How to Use the Library

Installation

Prerequisite: If you do not have the Anaconda Python distribution, install it here.

Create a Conda Environment for Cryo-forum:

  • More information on managing conda environments can be found here.
conda create --name cryoforum python=3.10
conda activate cryoforum

Install Dependencies:

pip install mrcfile wandb ipyvolume seaborn tensorflow_probability==0.20.0 tensorflow==2.12 tensorflow-graphics tensorflow_similarity scikit-image ipython_genutils notebook quaternion

Setup

Clone the Repository and Change Directory:

git clone https://github.com/phonchi/Cryo-forum.git
cd Cryo-forum

Tutorials and Guides

  • Explore the Example Notebook for detailed documentation and analysis on both synthetic and real datasets.

Data and Pretrained Model

License

Cryo-forum is released as open source software under the GNU General Public License, Version 3.

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A Framework for Orientation Recovery with Uncertainty Measurement in Cryo-EM Image Analysis

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