I can take a look. Can you tell me what version of RenPy you're using and send me a piece of your script where you're applying it, and the definitions of the displayable/layers you're applying them to?
Viewing post in Make Visual Novels! RenPy Shader Pack comments
Try slapping this either in a block under that, or in the Regicide transform definition.
mesh Trueso it would look like this:
show eileen happy with Regicide: mesh True
If that fixes it, I'll push out an update to make it part of the default Regicide setup. I thought I had already done that, but I might've missed it.