GPR39
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| G protein-spregnuti receptor 39 | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | GPR39; MGC149541 | ||||||||||
| Vanjski ID | OMIM: 602886 MGI: 1918361 HomoloGene: 20380 IUPHAR: GPR39 GeneCards: GPR39 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 2863 | 71111 | |||||||||
| Ensembl | ENSG00000183840 | ENSMUSG00000026343 | |||||||||
| UniProt | O43194 | Q9D442 | |||||||||
| RefSeq (mRNA) | NM_001508 | XM_913690 | |||||||||
| RefSeq (protein) | NP_001499 | XP_918783 | |||||||||
| Lokacija (UCSC) | Chr 2: 132.89 - 133.12 Mb | Chr 1: 127.5 - 127.7 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR39, G protein-spregnuti receptor 39, je protein koji je kod čoveka kodiran GPR39 genom.[1][2]
- ↑ McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH (Mar 1998). „Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors”. Genomics 46 (3): 426–34. DOI:10.1006/geno.1997.5069. PMID 9441746.
- ↑ „Entrez Gene: GPR39 G protein-coupled receptor 39”.
- Popovics P, Stewart AJ (2011). „GPR39: A Zn2+-activated G protein-coupled receptor that regulates pancreatic, gastrointestinal and neuronal functions.”. Cell. Mol. Life Sci. 68 (1): 85–95. DOI:10.1007/s00018-010-0517-1. PMID 20812023.
- Bonaldo MF, Lennon G, Soares MB (1997). „Normalization and subtraction: two approaches to facilitate gene discovery.”. Genome Res. 6 (9): 791–806. DOI:10.1101/gr.6.9.791. PMID 8889548.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Holst B, Holliday ND, Bach A, et al. (2005). „Common structural basis for constitutive activity of the ghrelin receptor family.”. J. Biol. Chem. 279 (51): 53806–17. DOI:10.1074/jbc.M407676200. PMID 15383539.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Hillier LW, Graves TA, Fulton RS, et al. (2005). „Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”. Nature 434 (7034): 724–31. DOI:10.1038/nature03466. PMID 15815621.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). „Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.”. Genome Res. 16 (1): 55–65. DOI:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Holst B, Egerod KL, Schild E, et al. (2007). „GPR39 signaling is stimulated by zinc ions but not by obestatin.”. Endocrinology 148 (1): 13–20. DOI:10.1210/en.2006-0933. PMID 16959833.
- Lauwers E, Landuyt B, Arckens L, et al. (2006). „Obestatin does not activate orphan G protein-coupled receptor GPR39.”. Biochem. Biophys. Res. Commun. 351 (1): 21–5. DOI:10.1016/j.bbrc.2006.09.141. PMID 17054911.
- Egerod KL, Holst B, Petersen PS, et al. (2007). „GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.”. Mol. Endocrinol. 21 (7): 1685–98. DOI:10.1210/me.2007-0055. PMID 17488974.
- Yasuda S, Miyazaki T, Munechika K, et al. (2007). „Isolation of Zn2+ as an endogenous agonist of GPR39 from fetal bovine serum.”. J. Recept. Signal Transduct. Res. 27 (4): 235–46. DOI:10.1080/10799890701506147. PMID 17885920.