E. Kale Edmiston

University of Pittsburgh Medical Center, Psychiatry, Post-Doc

Vanderbilt University, Neuroscience, Graduate Student

Vanderbilt University Medical Center, Program for LGBTI Health, Co-Director

China Medical University, Shenyang,China, Department of Radiological Sciences, Post-Doc

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For the most recent version of my CV, please see: http://tinyurl.com/EKaleEdmistonCV

Current/Ongoing Projects:
I am currently a T32 post doctoral scholar in Dr. Mary Phillips' lab at The University of Pittsburgh. I am working on projects related to risk for anxiety and emotional stimulus perception as a part of my ongoing research.

I have additional research interests in primary care access and outcomes for transgender people, as well as epistemological and bioethical approaches to transgender healthcare. As a graduate student, I served as Co-Director of The Program for LGBTI Health at Vanderbilt University Medical Center, and was also the Co-Founder and Director of The Trans Buddy Program, the first peer advocacy program for transgender people seeking healthcare.
Supervisors: Mary Phillips, Fei Wang, Blythe Corbett, and Hilary Blumberg

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Selçuk İşsever

Ankara University

James A. Coan

University of Virginia

Sarah-Jayne Blakemore

University College London

Krishna Prasad Miyapuram

Indian Institute of Technology Gandhinagar

Omar W. Nasim

University of Regensburg

Vittorio Gallese

Università degli Studi di Parma (Italy)

Keith Laws

University of Hertfordshire

Manuel Tironi

Pontificia Universidad Catolica de Chile

l.taggart@ulster.ac.uk Taggart

University of Ulster

Stephen Whittle

Manchester Metropolitan University

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Papers by E. Kale Edmiston

Neural activity changes in unaffected children of patients with schizophrenia: A resting-state fMRI study

Schizophrenia research, Jan 29, 2015

Previous neuroimaging studies have suggested that individuals at risk for schizophrenia exhibit s... more Previous neuroimaging studies have suggested that individuals at risk for schizophrenia exhibit structural and functional brain abnormalities. However, few studies focus on resting state baseline activity in individuals with genetic high-risk for schizophrenia (HR). We examined cerebral spontaneous neural activity in HR by measuring the amplitude of low frequency fluctuations (ALFF) in the blood oxygen level-dependent (BOLD) functional magnetic resonance signal during resting state. Using a 3T MRI scanner, 28 non-psychotic young adult participants with at least one parent with schizophrenia and 44 matched unrelated healthy comparison subjects (HC) were scanned during the resting-state. The ALFF of the BOLD signal for each participant was calculated, and these values were then compared between-groups using voxel-based analysis of the ALFF maps. The HR group showed significantly increased ALFF compared to the HC group in the striatum, including the left caudate nucleus extending to th...

Abnormal Morphological Correlations within a Cortico-Limbic Neural System in Adolescents with Bipolar Disorder

A comparative diffusion tensor imaging study of corpus callosum subregion integrity in bipolar disorder and schizophrenia

Psychiatry Research: Neuroimaging, 2014

Structural magnetic resonance imaging (MRI) studies have provided evidence for corpus callosum (C... more Structural magnetic resonance imaging (MRI) studies have provided evidence for corpus callosum (CC) white matter abnormalities in bipolar disorder (BD) and schizophrenia (SZ). These findings include alterations in shape, volume, white matter intensity and structural integrity compared to healthy control populations. Although CC alterations are implicated in both SZ and BD, no study of which we are aware has investigated callosal subregion differences between these two patient populations. We used diffusion tensor imaging (DTI) to assess CC integrity in patients with BD (n ¼16), SZ (n ¼ 19) and healthy controls (HC) (n ¼ 24). Fractional anisotropy (FA) of CC subregions was measured using region of interest (ROI) analysis and compared in the three groups. Significant group differences of FA values were revealed in five CC subregions, including the anterior genu, middle genu, posterior genu, posterior body and anterior splenium. FA values of the same subregions were significantly reduced in patients with SZ compared with HC. FA values were also significantly reduced in patients with BD compared to the HC group in the same subregions, excepting the middle genu. No significant difference was found between patient groups in any region. Most of the alterations in CC subregions were present in both the BD and SZ groups. These results imply an overlap in potential pathology, possibly relating to risk factors common to both disorders. The one region that differed between patient groups, the middle genu area, may serve as an illness marker and is perhaps involved in the different cognitive impairments observed in BD and SZ.

E. Kale Edmiston

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