American character actor born in Cincinnati and raised in Louisville, Mitchell Ryan was a well known supporting actor in films and television. Joined the Navy in 1951 at age 17 and was later assigned to the Special Services Entertainment and became hooked on acting. After his term in the Navy, he appeared in dozens of plays until he received notice as playing a regular in TV's Dark Shadows (1966).

Beginning in the 1970s, he received work in motion pictures including Monte Walsh (1970), Magnum Force (1973) and in Clint Eastwood's High Plains Drifter (1973). He had a small part in Universal's Midway (1976) and returned to act in numerous soaps and television series, among them included a recurring guest role in Having Babies (1978), Executive Suite (1976), The Chisholms (1979) and All My Children (1970) and a growing list of television films and TV guest appearances.

He may have been best-known for portraying the villain that Mel Gibson and Danny Glover are after in Lethal Weapon (1987), but his career included several supporting roles in the past ten years including Judge Dredd (1995), Michael Myers' nemesis in Halloween: The Curse of Michael Myers (1995), Liar Liar (1997) (with Jim Carrey), and as Harrison Ford's chief out to get Brad Pitt in the film The Devil's Own (1997).