npj Aging

Pairwise analysis of RNA sequencing data

Transcriptome analysis of cynomolgus macaques throughout their lifespan reveals age-related immune patterns

Hyeon-Mu Cho
Se-Hee Choe
Jae-Won Huh

Article 20 June 2024

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Rejuvenation of leukocyte trafficking in aged mice through PEPITEM intervention

Sophie J. Hopkin
Poppy Nathan
Myriam Chimen
Brief CommunicationOpen Access18 Jul 2024
Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice

Sanne J. M. Stefens
Nicole van Vliet
Ingrid van der Pluijm
ArticleOpen Access20 Jun 2024
Nodal degree centrality in the default mode-like network of the TgF344-AD Alzheimer’s disease rat model as a measure of early network alterations

Saba Amiri
Monica van den Berg
Georgios A. Keliris
ArticleOpen Access20 Jun 2024
Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study

Christopher E. Zwilling
Jisheng Wu
Aron K. Barbey
ArticleOpen Access21 May 2024

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Call for papers on Cancer and aging

This cross-journal Collection invites original research that explicitly explores the role of aging in cancer and vice versa, from the bench to the bedside.
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Call for papers on Generative AI for aging research and drug discovery. This Collection invites multidisciplinary groups to submit their research in Generative Artificial Intelligence for aging research and drug discovery.
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Atg5 in microglia regulates sex-specific effects on postnatal neurogenesis in Alzheimer’s disease

Ellen Walter
Gabrielle Angst
Chenran Wang
ArticleOpen Access16 Mar 2025
The role of inhibitory and excitatory neurometabolites in age-related differences in action selection

Geraldine Rodríguez-Nieto
Amirhossein Rasooli
Stephan P. Swinnen
ArticleOpen Access13 Mar 2025
Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance

Gesa Poetzsch
Luca Jelacic
Thomas Hankeln
ArticleOpen Access06 Mar 2025
Biomarkers of aging: functional aspects still trump molecular parameters

Biomarkers of aging are indispensable for testing interventions. While promising, the recent focus on molecular aspects should not detract from the functional parameters for which excellent correlation with mortality, and ample clinical human data exist.

Regula Furrer
Christoph Handschin
CommentOpen Access03 Mar 2025
Relationship between hearing thresholds and cognitive function in hearing aid non-users and long-term users post-midlife

Takanori Nishiyama
Tomomi Kimizuka
Naoki Oishi
ArticleOpen Access24 Feb 2025
Early vascular aging ambulatory score in acute ischemic stroke

Nikolaos Kakaletsis
Vasilios Kotsis
Christos Savopoulos
ArticleOpen Access21 Feb 2025
Characterization of senescence and nuclear reorganization in aging gingival cells

Christian Fernández
Diego Ormeno
Mónica Caceres
ArticleOpen Access21 Feb 2025
Calcium (Ca²⁺) fluxes at mitochondria-ER contact sites (MERCS) are a new target of senolysis in therapy-induced senescence (TIS)

Andrea Puebla-Huerta
Hernán Huerta
J. César Cárdenas
Brief CommunicationOpen Access21 Feb 2025
PTP-3 regulated by VB12 is important for ageing health in C. elegans

Man Zhu
Tao Lv
Yuhong Li
ArticleOpen Access21 Feb 2025

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Faculty Positions, Aging and Neurodegeneration, Westlake Laboratory of Life Sciences and Biomedicine

Applicants with expertise in aging and neurodegeneration and related areas are particularly encouraged to apply.

Hangzhou, Zhejiang, China

Westlake Laboratory of Life Sciences and Biomedicine (WLLSB)
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Shenzhen, Guangdong (CN)

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Principal Investigator Positions at the Chinese Institutes for Medical Research, Beijing

Cancer Biology, Molecular and Cellular Therapeutics, Regenerative Medicine, Immunology and Infectious Diseases, Genetics and etc...

Beijing, China

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In the compelling and unstoppable research in favor of cellular rejuvenation, Sentcell LTD is looking for Master/PhD student or Junior Postdoc (the...

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Transcriptome analysis of cynomolgus macaques throughout their lifespan reveals age-related immune patterns

Featured

Rejuvenation of leukocyte trafficking in aged mice through PEPITEM intervention

Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice

Nodal degree centrality in the default mode-like network of the TgF344-AD Alzheimer’s disease rat model as a measure of early network alterations

Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study

Announcements

Call for papers on Cancer and aging

CfP - Generative AI for aging research & drug discovery

Call for Papers - Reproductive Aging

Browse articles

Atg5 in microglia regulates sex-specific effects on postnatal neurogenesis in Alzheimer’s disease

The role of inhibitory and excitatory neurometabolites in age-related differences in action selection

Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance

Biomarkers of aging: functional aspects still trump molecular parameters

Relationship between hearing thresholds and cognitive function in hearing aid non-users and long-term users post-midlife

Early vascular aging ambulatory score in acute ischemic stroke

Characterization of senescence and nuclear reorganization in aging gingival cells

Calcium (Ca²⁺) fluxes at mitochondria-ER contact sites (MERCS) are a new target of senolysis in therapy-induced senescence (TIS)

PTP-3 regulated by VB12 is important for ageing health in C. elegans

Trending - Altmetric

Science jobs

Faculty Positions, Aging and Neurodegeneration, Westlake Laboratory of Life Sciences and Biomedicine

Open PI Positions at SMART

Talent Recruitment of Postdoctoral Fellow, SMART

Principal Investigator Positions at the Chinese Institutes for Medical Research, Beijing

PhD or Junior Postdoc to investigate molecular mechanisms in the field immune-rejuvenation

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Healthcare on the brink: navigating the challenges of an aging society in the United States

Rejuvenation of leukocyte trafficking in aged mice through PEPITEM intervention

Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop

Deficiency of angiotensin-converting enzyme 2 causes deterioration of cognitive function

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