Freeze Drying
Freeze Drying
Freeze Drying
Sanjana Bhattacharyya
Chemical Engineering
B. Tech. 3rd Year
Roll: 115537
INTRODUCTION
Technique to dry materials better than
conventional methods
Removes up to 99% of moisture
Used extensively in food, pharmaceutical
and chemical industries
Technique developed during WWII to
transport serum
BASIC PRINCIPLE
Sub-cooling
Ice nucleation
Crystallization
3.
Primary drying
o
o
o
MECHANISM OF FREEZE
DRYING-III
Secondary drying
4.
WORKING OF A FREEZE
DRYER
APPLICATIONS: PHARMACEUTICALSI
Shelf life of life saving medicines increased
Heat sensitive drugs and biologics can be
destroyed on drying at high temperature
Freeze dried products can be restored quickly
and easily in emergencies
Used in vaccines, antibodies, penicillin,
enzymes, hormones etc.
Freeze dried blood has great potential
OTHER APPLICATIONS
Used in restoring paper based documents
damaged by water
Water logged artifacts can be recovered for
museums
Used in taxidermy for pets and hunting
trophies
Used to preserve flowers and petals for
decorations
POSSIBLE IMPROVEMENTS
Can be made more time and energy
efficient
Can be economized for commercial uses
Development of better anti-freeze materials
will reduce mechanical injury to cell
Better stability can be provided in final
product, especially biologics
CONCLUSION
THANK
YOU!