Carnitine

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L-Carnitine

Outline
What is Carnitine? Types of carnitine What does carnitine do? Claims/Myths Facts about carnitine Side affects of supplementation Signs of deficiency Conclusion

By Shauna Blackwell

What is L-Carnitine?
Discovered in 1905 Nutrient found naturally in the human body Synthesized from lysine & methionine in kidney (Vit B6, Vit C, iron) Found in red meats, poultry, dairy
Caesin, egg whites, soy

Types of Carnitine
L-carnitine (levocarnitine)
Synthesized in body

D-carnitine & DL-carnitine


Over-the-counter Adverse effects

L-acetyl-carnitine
Alternative form

What does Carnitine do?


Shuttle long-chain fatty acids to the mitochondria within the cell Essential for the production of energy from fat

Claims/Myths
Promote weight loss/Increases energy levels Slows aging (immune system & cell deterioration) Prevents heart disease Enhances liver function Increases mental energy (relieves depression) Increases sperm motility

Claims for athletic benefits


Enhances aerobic performance Decrease muscle damage & soreness Increases blood flow and O2 to muscles Lowers ketone levels Helps burn branched chain amino acids

Facts of L-Carnitine Supplementation


No effect on athletic performance Proven helpful for the heart
angina, arrhythmias, heart failure Decreases heart rate Decreases blood pressure Decreases blood lipid levels

Who needs Supplementation?


Premature/Low weight babies Vegetarians Cardiac patients Diabetics Kidney disease Cancer patients Aids patients Depression Burn victims

SIDE EFFECTS OF SUPPLEMENTATION


Nausea Vomiting Stomach ache No known toxicity level Diarrhea Body odor

Overdose: severe muscle weakness

Supplementation
Generally Recognized As Safe (GRAS) Liquid or capsule of pure L-carnitine
250 1,000Mg doses

Deficiency
No RDI established Impaired lipid metabolism Lipid accumulation in skeletal muscles, heart, and liver Progressive muscle weakness Hypoglycemia Heart disturbances

With weight loss products


Hydroxycut Thermolean Coenzyme Q10

Conclusion
Unless a person is deficient in carnitine, there is no need for supplementation. Research has not proven any claim on carnitine in athletic improvement, weight loss, increased energy, or improved mental ability. You Are What You Eat

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