Music Therapy and Autism
Music Therapy and Autism
Music Therapy and Autism
This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library
2010, Issue 1
http://www.thecochranelibrary.com
TABLE OF CONTENTS
HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
PLAIN LANGUAGE SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
BACKGROUND . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
AUTHORS CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ACKNOWLEDGEMENTS
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
CHARACTERISTICS OF STUDIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DATA AND ANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Analysis 1.1. Comparison 1 Music therapy vs. placebo therapy, Outcome 1 Communicative skills: gestural. . . .
Analysis 1.2. Comparison 1 Music therapy vs. placebo therapy, Outcome 2 Communicative skills: verbal. . . . .
Analysis 1.3. Comparison 1 Music therapy vs. placebo therapy, Outcome 3 Behavioural problems (end of therapy).
Analysis 1.4. Comparison 1 Music therapy vs. placebo therapy, Outcome 4 Behavioural problems (using all measurements
from 2nd day on). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
WHATS NEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
CONTRIBUTIONS OF AUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DECLARATIONS OF INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
SOURCES OF SUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
INDEX TERMS
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[Intervention Review]
Contact address: Christian Gold, Grieg Academy Music Therapy Research Centre (GAMUT), Unifob Health, Lars Hilles gate 3,
Bergen, 5015, Norway. christian.gold@grieg.uib.no.
Editorial group: Cochrane Developmental, Psychosocial and Learning Problems Group.
Publication status and date: Edited (no change to conclusions), published in Issue 1, 2010.
Review content assessed as up-to-date: 28 January 2006.
Citation: Gold C, Wigram T, Elefant C. Music therapy for autistic spectrum disorder. Cochrane Database of Systematic Reviews 2006,
Issue 2. Art. No.: CD004381. DOI: 10.1002/14651858.CD004381.pub2.
Copyright 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
ABSTRACT
Background
The central impairments of people with autistic spectrum disorder (ASD) include social interaction and communication. Music therapy
uses music and its elements to enable communication and expression, thus attempting to address some of the core problems of people
with ASD.
Objectives
To review the effects of music therapy for individuals with autistic spectrum disorders.
Search strategy
The following databases were searched: CENTRAL, 2005, (Issue 3); Medline, (1966 to July 2004); Embase, (1980 to July 2004);
LILACS, (1982 to July 2004); PsycINFO, (1872 to July 2004); CINAHL, (1982 to July 2004); ERIC, (1966 to July 2004); ASSIA,
(1987 to July 2004); Sociofile, (1963 to July 2004); Dissertation Abstracts International, (late 1960s to July 2004). These searches
were supplemented by searching specific sources for music therapy literature and manual searches of reference lists. Personal contacts
to some investigators were made.
Selection criteria
All randomised controlled trials or controlled clinical trials comparing music therapy or music therapy added to standard care to
placebo therapy, no treatment or standard care.
Data collection and analysis
Studies were independently selected, quality assessed and data extracted by two authors. Continuous outcomes were synthesised using
a standardised mean difference (SMD) in order to enable a meta-analysis combining different scales, and to facilitate the interpretation
of effect sizes. Heterogeneity was assessed using the I statistic.
Main results
Three small studies were included (total n = 24). These examined the short-term effect of brief music therapy interventions (daily
sessions over one week) for autistic children. Music therapy was superior to placebo therapy with respect to verbal and gestural
communicative skills (verbal: 2 RCTs, n = 20, SMD 0.36 CI 0.15 to 0.57; gestural: 2 RCTs, n = 20, SMD 0.50 CI 0.22 to 0.79).
Effects on behavioural problems were not significant.
Music therapy for autistic spectrum disorder (Review)
Copyright 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Authors conclusions
The included studies were of limited applicability to clinical practice. However, the findings indicate that music therapy may help
children with autistic spectrum disorder to improve their communicative skills. More research is needed to examine whether the effects
of music therapy are enduring, and to investigate the effects of music therapy in typical clinical practice.
BACKGROUND
an attempt to compensate through alternative modes of communication such as gesture or mime); in individuals with adequate
speech, marked impairment in the ability to initiate or sustain a
conversation with others; stereotyped and repetitive use of language or idiosyncratic language; or a lack of varied, spontaneous
make-believe play or social imitative play appropriate to developmental level. Finally there must be restricted repetitive and stereotyped patterns of behavior, interests, and activities, as manifested
by at least one of the following: encompassing preoccupation with
one or more stereotyped and restricted patterns of interest that
is abnormal either in intensity or focus; apparently inflexible adherence to specific, nonfunctional routines or rituals; stereotyped
and repetitive motor mannerisms (e.g. hand or finger flapping or
twisting, or complex whole-body movements); or persistent preoccupation with parts of objects.
The age of onset is also a factor, and delays or abnormal functioning
in at least one of the following areas, with onset prior to age 3 years
is necessary: (1) social interaction, (2) language as used in social
communication, or (3) symbolic or imaginative play. DSM-IVTR also require that the disturbance is not better accounted for
by Retts Disorder or Childhood Disintegrative Disorder.
Individuals with autistic spectrum disorders have difficulties in
OBJECTIVES
records.
Data from rating scales were included only if the instrument was
either a self-report or completed by an independent rater or relative
(not the therapist).
METHODS
Types of studies
All relevant randomised controlled trials (RCTs) and controlled
clinical trials (CCTs).
Types of participants
Individuals of any age who are diagnosed with a pervasive developmental disorder, as defined in ICD-10 or DSM-IV, whether
identified by a psychological assessment or a psychiatric diagnosis. This includes childhood autism (F84.0 in ICD-10), atypical
autism (F84.1), Aspergers syndrome (F84.5), and pervasive developmental disorder not otherwise specified (F84.9). Individuals
with Retts disorder (F84.2) or childhood disintegrative disorder
(F84.3) are not included as they do not conventionally fall within
the autistic spectrum disorders, given their significantly different
clinical course.
Types of interventions
Music therapy (regular sessions of music therapy as defined above),
delivered by a professional, compared with either placebo (the
concept of attention placebo in psychotherapy research is discussed
in Kendall 2004), no-treatment or standard care control; or music
therapy added to standard care compared with standard care (with
or without placebo).
Types of outcome measures
Measures of the following including:
-Communicative and social skills, social interaction
-Quality of social interaction
-Behavioural problems (e.g. stereotypic behaviour)
-Attention and concentration
-Cognitive ability
-Hyperacusis (hypersensitivity to sound)
-Activity level
-Quality of life in both school and home environments
-Stress in the family
-Adverse events
Data sources could include non-standardised or standardised instruments (for a review of relevant standardised instruments see (
Ozonoff 2005), parent or teacher report, or school
RESULTS
Description of studies
See: Characteristics of included studies; Characteristics of excluded
studies; Characteristics of ongoing studies.
1. Excluded studies
The search yielded a total of 312 references. 52 of these were
deemed possibly relevant and selected for closer inspection. Of
these, 13 were excluded from the review because they concerned
an assessment rather than an intervention (e.g. assessing traits of
people with ASD using music therapy techniques). 24 studies were
excluded because they did not have an appropriate design (5 studies
with ABAB or similar designs, i.e. studies comparing different
treatments that all participants received in the same order; 10 case
series; 9 case studies). 7 studies employed an intervention involving
aims. For example, songs were based on a social story addressing a central problem behaviour of the particular individual in
treatment (Brownell 2002); they contained signs and words to be
learned (Buday 1995); or they were used to build a relationship
and to provide a safe and understandable structure for the participants in the study (Farmer 2003).
Active music-making by the participants, which is often typical for
music therapy in clinical practice (Wigram 2006), was reported
in only one study (Farmer 2003). Participants were allowed to
play guitar and drums. Playing instruments was partly used to
reinforce adjusted behaviour. The report did not specify whether
and in what ways the therapist improvised or otherwise played
music together with the client.
4.5.2 Placebo therapy
All studies compared music therapy to some kind of placebo
activity to control for the non-specific effects of therapeutic attention. Since in all studies music was considered as the specific ingredient of music therapy, the placebo conditions were constructed
to closely match the music therapy condition, only that music was
not used. For example, a social story was read instead of sung to the
participants (Brownell 2002); rhythmic speech was used instead
of singing (Buday 1995); or the same play activities were offered
without using songs or music instruments (Farmer 2003). Therefore, the placebo conditions included many elements similar to
the music therapy conditions, including some potentially active
ingredients (but none that are specific to music therapy). The concept of a placebo therapy designed to control for the therapists
attention has been widely used in psychotherapy research (Kendall
2004), but has also been criticised (Lambert 2004; see the discussion section of this review).
4.5.3 Other conditions
One study (Brownell 2002) also reported the outcomes during a
baseline and a washout period with no intervention. These data
were not used in this review.
4.6 Outcome measures
4.6.1 Communicative skills: gestural
Non-verbal (gestural) communicative skills were examined in two
studies (Buday 1995, Farmer 2003). Both studies addressed the
participants behaviour within therapy sessions. Independent observers counted the number of communicative gestures (e.g. imitating a sign or motion) in the session. In one study (Buday 1995),
the outcome consisted simply of the frequency count of appropriate gestures within a session. In the other study (Farmer 2003) a
completed gesture was given a score of 2 and an attempt a score
of 1, and the outcome consisted of the sum of these scores for all
attempted and completed gestures within a session. The exact criteria for what was seen as a communicative gesture were different
between the two studies. The measures used for this outcome were
not published.
4.6.2 Communicative skills: verbal
Communicative skills in verbal communication were addressed in
Effects of interventions
COMPARISON 1: MUSIC THERAPY versus PLACEBO
THERAPY
1. Communicative skills: gestural
Skills in non-verbal, gestural communication were measured on
continuous scales addressing observed behaviour. The results
showed a significant effect in favour of music therapy, suggesting that improvement in gestural communicative skills was more
likely to occur with music therapy than with a similar therapy not
including music (2 RCTs, n = 20, SMD 0.50 CI 0.22 to 0.79).
Results were consistent between the two studies (I = 0%; see figure 1.1).
2. Communicative skills: verbal
Observed skills in verbal communication were measured on continuous scales. The results showed a significant effect favouring
music therapy over the placebo intervention, suggesting that improvement in verbal communicative skills was more likely to occur
with music therapy (2 RCTs, n = 20, SMD 0.36 CI 0.15 to 0.57).
The results were consistent between studies (I = 0%; see figure
1.2).
3. Behavioural problems
The frequency of observed problem behaviour was measured on
a continuous scale. Data were only available from one trial with
four participants, and results were not significant when examining
only the last day in therapy (figure 1.3). However, when averaging
participants behaviour over all days in therapy except the first one
(figure 1.4), there was a significant effect suggesting that music
therapy may be slightly more beneficial than a similar verbal therapy in reducing behaviour problems (1 RCT, n = 4, SMD -0.24
CI -0.45 to -0.03).
DISCUSSION
Findings
Music therapy was compared to a placebo therapy which attempted to control for all non-specific elements of music therapy,
such as the attention of a therapist. Outcomes assessed included
communicative skills and behavioural problems, and results were
significant for communicative skills and reached borderline significance for behavioural problems, suggesting a beneficial effect of
music therapy.
The effect sizes found in the results of this review can be interpreted in accordance with common guidelines for interventions
in the behavioural sciences (Cohen 1988). The effect on non-verbal (gestural) communicative skills reached a medium effect size
(SMD 0.50), which is seen as a clinically relevant magnitude when
comparing an active therapy condition to a placebo therapy.
The effects on verbal communicative skills were slightly smaller
(SMD 0.36) and ranged between a small and a medium effect
Control conditions
AUTHORS CONCLUSIONS
Implications for practice
The findings of this review indicate that music therapy may have
positive effects on the communicative skills of children with autistic spectrum disorder. Music therapy has been shown to be superior to similar forms of therapy where music was not used, and
this may be indicative of a specificity of the effect of music within
music therapy. As only short-term effects have been examined, it
remains unknown how enduring the effects of music therapy on
verbal and non-verbal communicative skills are.
When applying the results of this review to practice, it is important
to note that the application of music therapy requires an academic
and clinical training in music therapy. Trained music therapists
are available in many countries. Training courses in music therapy
teach not only the clinical music therapy techniques as described
in the background of this review, but also aim at developing the
therapists personality and clinical sensitivity, which is necessary
to apply music therapy responsibly. Academic training courses in
music therapy exist in many countries, and information is usually
available through the professional associations.
this dilemma. An informed discussion is needed about what designs are considered appropriate in research on music therapy for
ASD.
ACKNOWLEDGEMENTS
We would like to thank Jane Dennis and Jo Abbott of the
Cochrane Developmental, Psychosocial and Learning Problems
Group for their help throughout the process, and Lisa Tjosvold of
the Cochrane Child Health Field for her help in retrieving additional unpublished studies.
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CHARACTERISTICS OF STUDIES
Participants
Diagnosis: autism.
N=4.
Age: range 6-9.
Sex: 4 M, 0 F.
Setting: elementary school.
Interventions
1. structured receptive MT (songs with social stories). 5 individual daily sessions. N=4.
2. structured receptive story therapy (reading of social stories). 5 individual daily sessions. N=4.
3. no intervention. 2 x 5 days. N=4.
Outcomes
Repetitive behaviours outside therapy sessions (in classroom). Inter-rater reliability 0.86 to 0.94
Notes
Risk of bias
Item
Authors judgement
Description
Allocation concealment?
Unclear
B - Unclear
Buday 1995
Methods
Allocation: randomised.
Blindness: assessor blinded to the nature of the hypothesis and to treatment condition.
Duration: 2 weeks.
Design: crossover.
Participants
Diagnosis: autism
N=10.
Age: range 4-9.
Sex: 8 M, 2 F.
Setting: public school.
Interventions
14
Buday 1995
(Continued)
Outcomes
Imitating behaviour in sessions (rating of a video recording with sound turned off to ensure blinding of
raters; inter-rater agreement 98%).
a) sign imitation
b) speech imitation
Notes
Risk of bias
Item
Authors judgement
Description
Allocation concealment?
Unclear
B - Unclear
Farmer 2003
Methods
Allocation: randomised.
Blindness: not known.
Duration: 5 days.
Design: parallel group.
Participants
Diagnosis: autism.
N=10.
Age: range 2-5.
Sex: 9 M, 1 F.
Setting: homes and therapy centres.
Interventions
Outcomes
Notes
Risk of bias
Item
Authors judgement
Description
Allocation concealment?
Unclear
B - Unclear
15
Applebaum 1979
Bettison 1996
Blackstock 1978
Bonnel 2003
Brown 1994
Brown 2003
Bruscia 1982
Carroll 1983
Chilcote-Doner 1982
Clauss 1994
Dawson 1998
Diez 1989
Edelson 1999
Edgerton 1994
Frissell 2001
Goldstein 1964
Gore 2002
Griggs 1997
Hadsell 1988
Hairston 1990
Heaton 1999
Heaton 2003
16
(Continued)
Kolko 1980
Krauss 1982
Lee 2004
Litchman 1976
Ma 2001
Mahlberg 1973
Miller 1979
Mottron 2000
Mudford 2000
OConnell 1974
OLoughlin 2000
not RCT/CCT - includes 3 case series where all received the same treatment (no. 1, 3, 4) and 1 case series
with an ABA design (no. 2).
Pasiali 2004
Rao 2001
Saperston 1973
Schmidt 1976
Starr 1998
Staum 1984
Stevens 1969
Thaut 1987
Thaut 1988
Toolan 1994
Watson 1979
Wimpory 1995
17
Joint attention and attunement in improvisational music therapy with the autistic child
Methods
Participants
Interventions
Outcomes
Starting date
2003
Contact information
Notes
18
No. of
studies
No. of
participants
Statistical method
Effect size
2
2
1
Analysis 1.1. Comparison 1 Music therapy vs. placebo therapy, Outcome 1 Communicative skills: gestural.
Review:
Study or subgroup
SMD (SE)
SMD
Weight
IV,Fixed,95% CI
SMD
IV,Fixed,95% CI
Buday 1995
0.4756 (0.1504)
95.8 %
Farmer 2003
1.1676 (0.7159)
4.2 %
100.0 %
-4
-2
Favours placebo
Favours MT
19
Analysis 1.2. Comparison 1 Music therapy vs. placebo therapy, Outcome 2 Communicative skills: verbal.
Review:
Study or subgroup
SMD (SE)
SMD
Weight
IV,Fixed,95% CI
SMD
IV,Fixed,95% CI
Buday 1995
0.3471 (0.1097)
97.4 %
Farmer 2003
0.8066 (0.6736)
2.6 %
100.0 %
-4
-2
Favours placebo
Favours MT
Analysis 1.3. Comparison 1 Music therapy vs. placebo therapy, Outcome 3 Behavioural problems (end of
therapy).
Review:
Study or subgroup
SMD (SE)
SMD
Weight
IV,Fixed,95% CI
Brownell 2002
SMD
IV,Fixed,95% CI
-0.141 (0.141)
100.0 %
100.0 %
-1
-0.5
Favours MT
0.5
Favours placebo
20
Analysis 1.4. Comparison 1 Music therapy vs. placebo therapy, Outcome 4 Behavioural problems (using
all measurements from 2nd day on).
Review:
Study or subgroup
SMD (SE)
SMD
Weight
SMD
IV,Fixed,95% CI
Brownell 2002
IV,Fixed,95% CI
-0.2405 (0.1091)
100.0 %
100.0 %
-1
-0.5
Favours MT
0.5
Favours placebo
WHATS NEW
Last assessed as up-to-date: 28 January 2006.
5 November 2009
Amended
HISTORY
Protocol first published: Issue 3, 2003
Review first published: Issue 2, 2006
10 November 2008
Amended
21 February 2006
Amended
Minor update
29 January 2006
Substantive amendment
21
CONTRIBUTIONS OF AUTHORS
CG - designed the protocol, co-ordinated the reviewing, searched for studies, extracted and analysed data, and wrote the report.
TW - extracted and analysed data, helped with writing the protocol and the report.
CE - helped with data extraction and analysis and with writing the report.
DECLARATIONS OF INTEREST
The authors of this review are clinically trained music therapists.
SOURCES OF SUPPORT
Internal sources
Sogn og Fjordane University College, Norway.
Aalborg University, Denmark.
External sources
The Research Council of Norway, Norway.
INDEX TERMS
Medical Subject Headings (MeSH)
Autistic Disorder [ rehabilitation]; Child Development Disorders, Pervasive [ rehabilitation]; Communication; Music Therapy
[ methods]; Randomized Controlled Trials as Topic
22