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CEFIXIME

Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.

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Jesrel Delota
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552 views

CEFIXIME

Cefixime is a cephalosporin antibiotic used to treat infections. It works by inhibiting bacterial cell wall synthesis. It is 40-50% absorbed orally and distributed to bile, urine, and crosses the placenta. It is 20% excreted unchanged in urine and 60% eliminated nonrenally, some in feces. Nursing responsibilities include reviewing dosing and therapy length, instructing on administration and advising to complete the course and report side effects or worsening symptoms.

Uploaded by

Jesrel Delota
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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GENERIC NAME

CEFIXIME

BRAND NAME
CLASSIFICATION
MODE OF ACTION

Fixivin

DATE ORDERED
DOSAGE
INDICATION

CONTRAINDICATIONS
ADVERSE EFFECTS

cephalosporin antibiotic

Cefixime binds to one or more of the penicillin-binding


proteins (PBPs) which inhibits the final transpeptidation
step of peptidoglycan synthesis in bacterial cell wall,
thus inhibiting biosynthesis and arresting cell wall
assembly resulting in bacterial cell death.
Absorption: Only 40-50% is absorbed from the GI tract
(oral); rate may be decreased if taken with food.
Greater absorption from oral suspension than tablets.
Distribution: Bile, urine (high concentrations); crosses
the placenta. Protein-binding: 65%.
Excretion: 20% of an oral dose excreted via urine
unchanged; 60% nonrenal elimination; some is
excreted via the feces from the bile. Substantially
removed by dialysis.
07/26/13 (Post-operative)
100mg / 5ml; syrup, 1.5 ml BID
To reduce the development of drug resistant bacteria
and maintain the effectiveness of Suprax (cefixime) and
other antibacterial drugs, Suprax should be used only
to treat infections that are proven or strongly suspected
to be caused by susceptible bacteria.
Hypersensitivity to cephalosporin.
Diarrhoea, nausea, vomiting, abdominal pain;
headache, dizziness, thrombocytopenia, eosinophilia.

NURSING
RESPONSIBILITIES

Review dosing schedule and prescribed length


of therapy with patient.

Instruct patient or caregiver to shake well before


measuring dose, and to measure and administer
prescribed dose using dosing spoon, dosing
syringe, or medicine cup.

Advise patient to take without regard to meals

but to take with food if GI upset occurs.

Instruct patient to complete entire course of


therapy even if symptoms of infection have
disappeared.

Advise patient to discontinue therapy and


contact health care provider immediately if skin
rash, hives, itching, or shortness of breath occur.

Advise patient to report the following signs of


superinfection to health care provider: black furry
tongue, foul-smelling stools, vaginal itching or
discharge, white patches in mouth.

Instruct patient to notify health care provider if


infection does not appear to improve or worsens.

Instruct patient to immediately report severe


diarrhea, diarrhea containing blood or pus, or
severe abdominal cramping.

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