Scribd Logo
Upload

Welcome to Scribd!

  • 729 views

    mcq ثاني

    Uploaded by

    محمدأميندماج
    The document contains questions about antibiotics, including penicillins and cephalosporins. It addresses their generations, spectra of activity, mechanisms of action, dosing considerations like with renal impairment, which are beta-lactamase resistant or require inhibitors, and appropriate uses for conditions like neutropenia or pneumonia.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    mcq ثاني

    Uploaded by

    محمدأميندماج
    729 views4 pages
    The document contains questions about antibiotics, including penicillins and cephalosporins. It addresses their generations, spectra of activity, mechanisms of action, dosing considerations like with renal impairment, which are beta-lactamase resistant or require inhibitors, and appropriate uses for conditions like neutropenia or pneumonia.

    Original Description:

    choose

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    The document contains questions about antibiotics, including penicillins and cephalosporins. It addresses their generations, spectra of activity, mechanisms of action, dosing considerations like with renal impairment, which are beta-lactamase resistant or require inhibitors, and appropriate uses for conditions like neutropenia or pneumonia.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    729 views4 pages

    mcq ثاني

    Uploaded by

    محمدأميندماج
    The document contains questions about antibiotics, including penicillins and cephalosporins. It addresses their generations, spectra of activity, mechanisms of action, dosing considerations like with renal impairment, which are beta-lactamase resistant or require inhibitors, and appropriate uses for conditions like neutropenia or pneumonia.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    You are on page 1of 4
    At a glance
    Powered by AI
    The passages discuss different generations of cephalosporins and penicillins, their characteristics, mechanisms of action, and factors affecting dosing such as renal function.

    First generation cephalosporins are cefazolin and cephalexin. Second generation include cefaclor and cefuroxime. Third generation are ceftriaxone, cefotaxime and others. Fourth generation is cefepime. Later generations have broader spectra but greater resistance. Each generation has differences in spectrum, dosing, and side effects.

    Penicillin G is administered via injection and has the narrowest spectrum. It is acid labile. Other penicillins include amoxicillin, ampicillin and others which are administered orally and some are acid stable/resistant. Duration of action also varies between different penicillins.

    32. Which of the following statement about Penicillin G is true?

    a. It is commonly administered orally


    b. It has a broad spectrum of antibacterial activity
    c. It can be used for the treatment rate bite fever
    d. Concomitant probenecid decreases its duration of action

    23. A bactericidal drug would be preferred over a bacteriostatic


    drug in a patient with:

    a. Neutropenia
    b. Cirrhosis
    c. Pneumonia
    d. Heart disease

    10. All of the following antibacterial agents act by inhibiting cell


    wall synthesis EXCEPT: (AI

    a. Carbapenams
    b. Monobactams
    c. Cephalosporins
    d. Nitrofurantoin

    Which one of the following drugs is an antipseudomonal


    penicillin?

    a. Cephalexin
    b. Cloxacillin
    c. Piperacillin
    d. Dicloxacillin

    34. Which of the following beta-lactam antibiotics can be safely


    used in a patient with a history of allergy to penicillins?

    a. Aztreonam
    b. Cefipime
    c. Loracarbef
    d. Ceftriaxone

    36. All are true about cephalosporins, except :

    a. Ceftazidime is a 3rd generation cephalosporin.


    b. Cefoperazone has got antipseudomonal effect.
    c. Cefoxitin has got no activity against anaerobes.
    d. Cephalosporins act by inhibiting cell wall synthesis.

    37. Cephalosporin that does not require dose reduction in patient


    with any degree of renal impairment is:

    a. Cefuroxime
    b. Cefoperazone
    c. Ceftazidime
    d. Cefotaxime
    39. All of the following statements about penicillin G are true
    EXCEPT:

    a. It is actively secreted in tubules


    b. It is never administered orally
    c. It is effective against gram positive as well as some gram negative
    bacteria
    d. It acts by inhibiting cell wall synthesis

    42. One of the following is not penicillinase susceptible?

    a. Amoxicillin
    b. Penicillin G
    c. Piperacillin
    d. Cloxacillin

    44. Which of the following is a fourth generation cephalosporin?

    a. Ceftriaxone
    b. Cefaclor
    c. Cefipime
    d. Cefuroxime

    46. Which of the following statements are true regarding


    Cefipime:

    a. It is a fourth generation cephalosporin


    b. Once a day dose is sufficient
    c. It possess antipseudomonal action
    d. Its dose should not be reduced in renal pathology
    e. It is a prodrug

    51. The penicillin G preparation with the longest duration of


    action is:

    a. Benzathine penicillin
    b. Sodium penicillin
    c. Potassium penicillin
    d. Procaine penicillin

    59. Cilastatin is given along with:

    a. Imipenem
    b. Amoxicillin
    c. Erythromycin
    d. Ampicillin

    61. Which of the following is not true about penicillins?

    a. Penicillin V is absorbed orally


    b. Benzathine penicillin is short acting penicillin
    c. Cloxacillin is b-lactamase and acid resistant
    d. Ampicillin is not resistant to b-lactamases
    66. Amoxycillin is better than ampicillin due to:

    a. Better bioavailability if taken with food


    b. Lesser bioavailability if taken with food
    c. Incidence of diarrhea is higher
    d. More active against Shigella and H. influenza

    74. Third generation cephalosporin that can be given orally is:

    a. Cefipime
    b. Cefpirome
    c. Cefaclor
    d. Cefadroxil

    69. Ceftriaxone is:

    a. 2nd generation short acting cephalosporin


    b. Has activity against beta lactamase producing bacteria
    c. 4th generation long acting cephalosporin
    d. 3rd generation long acting cephalosporin

    70. Acid susceptible penicillin is:

    a. Methicillin
    b. Ampicillin
    c. Amoxicillin
    d. Cloxacillin

    71. All are first generation cephalosporins except:

    a. Cefadroxil
    b. Cefazolin
    c. Cephalexin
    d. Cefaclor

    72. Which is not a beta lactam antibiotic?

    a. Penicillin
    b. Carbapenam
    c. Monobactam
    d. Azithromycin

    73. Second generation cephalosporin that can be used orally is:


    (MH 2003)

    a. Cefepime
    b. Cefalothin
    c. Cefaclor
    d. Cefadroxil

    76. Which among the following is not a beta lactamase inhibitor?

    a. Sulbactam
    b. Clavulanic acid
    c. Piperacillin
    d. None

    77. Oral cephalosporin among these is:

    a. Cefotaxime
    b. Ceftriaxone
    c. Cefaclor
    d. Ceftazidime

    78. Beta lactam antibiotics act by inhibiting

    a. Cell wall synthesis


    b. Protein synthesis
    c. RNA synthesis
    d. DNA synthesis

    79. Which one of the following is a fourth generation


    cephalosporin?

    a. Cefuroxime
    b. Ceftazidime
    c. Cefepime
    d. Cefamandole

    80. Neutropenia is associated with:

    a. Nafcillin
    b. Methicillin
    c. Carbenicillin
    d. Ampicillin

    81. Third-generation cephalosporins include all of the following


    EXCEPT:

    a. Ceftizoxime
    b. Cefoperazone
    c. Cefoxitin
    d. Cefixime

    82. Which one of the following statement about imipenem is most


    accurate?

    a. The drug has a narrow spectrum of anti-bacterial action


    b. It is used in fixed combination with Sulbactam
    c. Imipenem is highly susceptible to beta lactamase produced by
    enterobacteriaciae
    d. In renal dysfunction, dosage reduction are necessary to avoid
    seizures

    You might also like

    pFad - Phonifier reborn

    Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

    Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


    Alternative Proxies:

    Alternative Proxy

    pFad Proxy

    pFad v3 Proxy

    pFad v4 Proxy