Scribd Logo
Upload

Welcome to Scribd!

  • 284 views

    Pka Bases

    Uploaded by

    Carlos Arzaluz
    This document provides pKa values for common bases. It notes that the pKa values listed refer to the conjugate acids of the bases. Some examples include hydroxide with a pKa of 15.7, methoxide with a pKa of 15-16, ethoxide with a pKa of 16, and isopropoxide and tert-butoxide with pKa values of 16.5 and 17 respectively. Amines generally have pKa values between 9-10 while acetates have a pKa of 4.76. Various lithium bases like methyllithium and n-butyllithium have pKa values around 50.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Pka Bases

    Uploaded by

    Carlos Arzaluz
    284 views1 page
    This document provides pKa values for common bases. It notes that the pKa values listed refer to the conjugate acids of the bases. Some examples include hydroxide with a pKa of 15.7, methoxide with a pKa of 15-16, ethoxide with a pKa of 16, and isopropoxide and tert-butoxide with pKa values of 16.5 and 17 respectively. Amines generally have pKa values between 9-10 while acetates have a pKa of 4.76. Various lithium bases like methyllithium and n-butyllithium have pKa values around 50.

    Original Description:

    Pka de bases orgánicas.

    Original Title

    pka_bases

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document provides pKa values for common bases. It notes that the pKa values listed refer to the conjugate acids of the bases. Some examples include hydroxide with a pKa of 15.7, methoxide with a pKa of 15-16, ethoxide with a pKa of 16, and isopropoxide and tert-butoxide with pKa values of 16.5 and 17 respectively. Amines generally have pKa values between 9-10 while acetates have a pKa of 4.76. Various lithium bases like methyllithium and n-butyllithium have pKa values around 50.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    284 views1 page

    Pka Bases

    Uploaded by

    Carlos Arzaluz
    This document provides pKa values for common bases. It notes that the pKa values listed refer to the conjugate acids of the bases. Some examples include hydroxide with a pKa of 15.7, methoxide with a pKa of 15-16, ethoxide with a pKa of 16, and isopropoxide and tert-butoxide with pKa values of 16.5 and 17 respectively. Amines generally have pKa values between 9-10 while acetates have a pKa of 4.76. Various lithium bases like methyllithium and n-butyllithium have pKa values around 50.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    pKa Values of Common Bases

    Values in H2O as much as possible, so common comparisons (i.e., H2O pKa = 15.7) can still be used

    Note; The pKa values associated with bases is normally meant to refer to the true pKa's of their conjugate
    acids; i.e., pKa associated with HO- is 15.7, which is the pKa of H2O. This is often sloppily used by
    organic chemists, and can lead to confusion, especially with amines.

    CH3 H3C CH3


    O H3C OH
    H H H3C OH
    H3C OH H3C OH
    CH3 H3C CH3
    base is H O- H3C O-
    H3C O-
    H3C O- H3C O-
    pKa 15.7 pKa 15-16 pKa 16 pKa 16.5 pKa 17
    hydroxide methoxide ethoxide isopropoxide tert-butoxide

    O O
    R R
    - N+
    O OH R H H3C OH
    O the very weak bases
    O
    base is - - :NR3
    O O
    H3C O-

    pKa 10 pKa 9-10 pKa 4.76


    carbonate amine acetate
    (carboxylate)

    H2 (H-H)
    NH3 N
    H N
    H
    base is -
    NH2
    Na-H
    N-Li+ or
    N- K-H
    Li+
    pKa 35 pKa 35.7 pKa 37.1 pKa 35
    amide lithium diisopropyl amide lithium tetramethyl- hydride bases
    LDA piperidide (LiTMP)

    H H H H H H H CH3
    CH3
    H H H3C H H3C H3C CH3

    Li Li CH3
    H3C Li CH3 H3C CH3
    base is CH3-Li H3C

    pKa 48 pKa 50 pKa 51 pKa (53)?


    methyllithium n-butyllithium sec-butyllithium tert-butyllithium
    MeLi n-BuLi s-BuLi t-BuLi

    You might also like

    pFad - Phonifier reborn

    Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

    Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


    Alternative Proxies:

    Alternative Proxy

    pFad Proxy

    pFad v3 Proxy

    pFad v4 Proxy