SAFETY DATA SHEET

Creation Date 08-Jul-2010 Revision Date 08-Mar-2018 Revision Number 4

1. Identification
Product Name Gentamycin Sulfate

Cat No. : BP918-1

CAS-No 1405-41-0
Synonyms Garamycin; Gentamycin sulfate

Recommended Use Laboratory chemicals.

Uses advised against Not for food, drug, pesticide or biocidal product use

Details of the supplier of the safety data sheet

Company
Fisher Scientific
One Reagent Lane
Fair Lawn, NJ 07410
Tel: (201) 796-7100

Emergency Telephone Number

CHEMTRECÒ, Inside the USA: 800-424-9300
CHEMTRECÒ, Outside the USA: 001-703-527-3887

2. Hazard(s) identification
Classification
This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Respiratory Sensitization Category 1

Skin Sensitization Category 1

Label Elements

Signal Word
Danger

Hazard Statements
May cause an allergic skin reaction
May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

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Prevention
Avoid breathing dust/fume/gas/mist/vapors/spray
In case of inadequate ventilation wear respiratory protection
Contaminated work clothing should not be allowed out of the workplace
Wear protective gloves
Inhalation
IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing
If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician
Skin
IF ON SKIN: Wash with plenty of soap and water
If skin irritation or rash occurs: Get medical advice/attention
Wash contaminated clothing before reuse
Disposal
Dispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC)
None identified

3. Composition/Information on Ingredients
Component CAS-No Weight %
Gentamicin, sulfate (salt) 1405-41-0 >95

4. First-aid measures
General Advice If symptoms persist, call a physician.

Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get
medical attention.

Skin Contact Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists,
call a physician.

Inhalation Move to fresh air. If not breathing, give artificial respiration. Get medical attention if
symptoms occur.

Ingestion Clean mouth with water and drink afterwards plenty of water. Get medical attention if
symptoms occur.

Most important symptoms and None reasonably foreseeable. May cause allergy or asthma symptoms or breathing
effects difficulties if inhaled. May cause allergic skin reaction. Symptoms of allergic reaction may
include rash, itching, swelling, trouble breathing, tingling of the hands and feet, dizziness,
lightheadedness, chest pain, muscle pain or flushing
Notes to Physician Treat symptomatically

5. Fire-fighting measures
Suitable Extinguishing Media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Unsuitable Extinguishing Media No information available

Flash Point Not applicable

Method - No information available

Autoignition Temperature
Explosion Limits
Upper No data available
Lower No data available
Sensitivity to Mechanical Impact No information available

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Sensitivity to Static Discharge No information available

Specific Hazards Arising from the Chemical

Keep product and empty container away from heat and sources of ignition.

Hazardous Combustion Products

Carbon monoxide (CO) Carbon dioxide (CO2) Nitrogen oxides (NOx)
Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full
protective gear.

NFPA
Health Flammability Instability Physical hazards
2 1 0 N/A

6. Accidental release measures

Personal Precautions Ensure adequate ventilation. Use personal protective equipment. Avoid dust formation.
Environmental Precautions Should not be released into the environment.

Methods for Containment and Clean Sweep up or vacuum up spillage and collect in suitable container for disposal. Keep in
Up suitable, closed containers for disposal.

7. Handling and storage

Handling Wear personal protective equipment. Avoid dust formation. Do not get in eyes, on skin, or
on clothing. Avoid ingestion and inhalation. Ensure adequate ventilation.

Storage Keep containers tightly closed in a dry, cool and well-ventilated place. To maintain product
quality: Keep refrigerated.

8. Exposure controls / personal protection

Exposure Guidelines This product does not contain any hazardous materials with occupational exposure
limitsestablished by the region specific regulatory bodies.

Engineering Measures Use only under a chemical fume hood. Ensure that eyewash stations and safety showers
are close to the workstation location.

Personal Protective Equipment

Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.

Skin and body protection Long sleeved clothing.

Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or other symptoms are experienced.

Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.

9. Physical and chemical properties

Physical State Solid
Appearance White
Odor Odorless
Odor Threshold No information available

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pH 3.5 - 5.5 (4 %)
Melting Point/Range 218 - 237 °C / 424.4 - 458.6 °F
Boiling Point/Range No information available
Flash Point Not applicable
Evaporation Rate Not applicable
Flammability (solid,gas) No information available
Flammability or explosive limits
Upper No data available
Lower No data available
Vapor Pressure No information available
Vapor Density Not applicable
Specific Gravity No information available
Solubility Soluble in water
Partition coefficient; n-octanol/water No data available
Autoignition Temperature
Decomposition Temperature No information available
Viscosity Not applicable

10. Stability and reactivity

Reactive Hazard None known, based on information available

Stability Stable under normal conditions.

Conditions to Avoid Incompatible products. Excess heat. Avoid dust formation.

Incompatible Materials Strong oxidizing agents

Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2), Nitrogen oxides (NOx)

Hazardous Polymerization Hazardous polymerization does not occur.

Hazardous Reactions None under normal processing.

11. Toxicological information

Acute Toxicity

Product Information
Component Information
Component LD50 Oral LD50 Dermal LC50 Inhalation
Gentamicin, sulfate (salt) >5 g/kg ( Rat ) Not listed Not listed
Toxicologically Synergistic No information available
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure

Irritation May cause eye, skin, and respiratory tract irritation

Sensitization May cause sensitization by inhalation and skin contact

Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.

Component CAS-No IARC NTP ACGIH OSHA Mexico

Gentamicin, sulfate 1405-41-0 Not listed Not listed Not listed Not listed Not listed
(salt)
Mutagenic Effects No information available

Reproductive Effects May impair fertility.

Developmental Effects No information available.

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Teratogenicity No information available.

STOT - single exposure None known

STOT - repeated exposure None known

Aspiration hazard No information available

Symptoms / effects,both acute and Symptoms of allergic reaction may include rash, itching, swelling, trouble breathing, tingling
delayed of the hands and feet, dizziness, lightheadedness, chest pain, muscle pain or flushing

Endocrine Disruptor Information No information available

Other Adverse Effects The toxicological properties have not been fully investigated.

12. Ecological information

Ecotoxicity
Do not empty into drains.

Persistence and Degradability Soluble in water Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation No information available.

Mobility Will likely be mobile in the environment due to its water solubility.

13. Disposal considerations

Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.

14. Transport information

DOT Not regulated
TDG Not regulated
IATA Not regulated
IMDG/IMO Not regulated
15. Regulatory information
All of the components in the product are on the following Inventory lists: X = listed

International Inventories

Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL
Gentamicin, sulfate (salt) - - - 215-778-9 - X X X X X
Legend:
X - Listed
E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.
P - Indicates a commenced PMN substance
R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.
S - Indicates a substance that is identified in a proposed or final Significant New Use Rule
T - Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).
Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants
that comprises one of the eligibility criteria for the exemption rule.

U.S. Federal Regulations

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TSCA 12(b) Not applicable

SARA 313 Not applicable

SARA 311/312 Hazard Categories See section 2 for more information

CWA (Clean Water Act) Not applicable

Clean Air Act Not applicable

OSHA Occupational Safety and Health Administration

Not applicable

CERCLA Not applicable

California Proposition 65

Component CAS-No California Prop. 65 Prop 65 NSRL Category

Gentamicin, sulfate (salt) 1405-41-0 Gentamicin Sulfate -
U.S. State Right-to-Know Not applicable
Regulations

U.S. Department of Transportation

Reportable Quantity (RQ): N

DOT Marine Pollutant N
DOT Severe Marine Pollutant N

U.S. Department of Homeland Security

This product does not contain any DHS chemicals.

Other International Regulations

Mexico - Grade No information available

16. Other information

Prepared By Regulatory Affairs
Thermo Fisher Scientific
Email: EMSDS.RA@thermofisher.com

Creation Date 08-Jul-2010

Revision Date 08-Mar-2018
Print Date 08-Mar-2018
Revision Summary This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).

Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text

End of SDS

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