TAGUM DOCTORS COLLEGE INC.

Mahogany St., Rabe Subdivision Tagum City

Bachelor of Science in Nursing

DRUG STUDY
Name of Student : Sian, Liza P. – BSN3, Group 1
Name of Client : Paradiang, Clinton Age: 9 y.o. Sex: Male Rating:
Date of assessment: Sept. 13, 2018 Physician: Dr. Lagmay Status:
Chief complaint : Fever Admitting diagnosis: SVI r/o Dengue fever

Date Image of Drug Name of Drug Classification Dosage/ Mechanism of Action

Time/Route
Sep. 11, Brand name: antiinfective; 750mg, Q8, Ampicillin inhibits bacterial cell wall synthesis by
2018 Ampicillin antibiotic; IVTT binding to 1 or more of the penicillin-binding proteins
Sodium aminopenicillin (PBPs) which in turn inhibit the final transpeptidation
step of peptidoglycan synthesis in bacterial cell walls.
Generic name: Bacteria eventually lyse due to ongoing activity of
Ampicillin cell wall autolytic enzymes (autolysins and murein
Omnipen hydrolases) while cell wall assembly is arrested.
Pharmacology:
Pharmacokinetics
Absorption: Moderately well absorbed from the GI
tract (50%). Food may reduce rate and extent of
absorption. Time to peak plasma concentration:
Approx 1-2 hr.
Distribution
Widely distributed. Crosses the placenta and enters
breast milk (small amounts). Plasma protein binding:
Approx 20%.
Metabolism
Metabolised to some extent to penicilloic acid.
Excretion
Via urine as unchanged drug (oral: approx 20-40%;
parenteral: approx 60-80%) w/in 6 hr and faeces
(small amounts). Plasma half-life: Approx 1-1.5 hr.
 Indication Contraindications Adverse Reaction Nursing Responsibilities
Supplement in systemic Contraindicated to CNS: 1. Assess for allergies to penicillin cephaloporins, or other
therapy for treatment of patients with Lethargy hallucinations, allergens and renal disorder.
susceptible infections, allergies to seizures 2. Culture infected area before treatment; reculture area if
Meningitis, Intrapartum penicillin's, CV: respose is not as expected.
prophylaxis against group B cephalosporin's, or CHF 3. Check IV site carefully for signs of thrombosis or drug
Streptoccocal infection in other allergens GI: reaction.
neonates Glossitis, stomatitis, 4. Inform patient that ampicillin contain inactive
gastritis, sore mouth, ingredients, which can cause allergic reactions or other
furry tongue, black "hairy" problems.
tongue, nausea, vomiting, 5. Teach patient to report pain or discomfort at sites,
diarrhea, abdominal pain unusual bleeding or bruising, mouth sores, rash, hives,
GU: fever, itching, sever diarrhea, difficulty of breathing.
Nephritis 6. Ampicillin may cause live bacterial vaccines (such as
Hematologic: typhoid vaccine) to not work as well. Do not have any
Anemia, immunizations/vaccinations while using this medication.
thrombocytopenia, 7. Store between 20-25°C (discard after 14 days).
leukaemia, neutropenia 8. Precaution to patient w/ history of β-lactam allergy.
Local: Renal impairment. Pregnancy and lactation.
Pain, phlebitis, 9. Monitor renal, hepatic, and haematologic function
thrombosis at injection periodically; observe signs and symptoms of
site anaphylaxis during 1st dose.
Other:
Superinfections- oral and
rectal moniliasis
Reference: www.rnpedia.com