Drug Study Methergine

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DRUG STUDY

NAME: DATE: 2/19/2022 BLOCK: UP-FC2-BSN2-12 HOSPITAL/AREA: NA


CLINICAL INSTRUCTOR:
NAME OF THE MECHANISM CONTRAINDICATIONS SIDE EFFECTS ADVERSE EFFECTS NURSING RATIONALE
DRUG OF ACTION RESPONSIBILITIES

Generic name Acts directly on the 1ST stage and 2nd stage of Nausea Common: Assess calcium level Hypocalcemia must be
smooth muscle of labor before crowning of Vomiting  Abdominal pain w/ before administering corrected to increase drug
the uterus and head, primary and Stomach pain large doses therapy. effectiveness
increases the tone, secondary uterine inertia. Diarrhea  Hypertension
Methylergonovine rate, and amplitude Patient with severe Leg cramps  Headache
maleate of rhythmic hypertension, pre- Increased sweating  Skin eruption
contractions. It eclampsia, eclampsia, Headache Uncommon:
Brand name includes rapid, severe or persistent sepsis, Dizziness Monitor vital signs. In administering
 Dizziness Methylergonovine maleate
Methergine sustained tetanic vascular disease, impaired Ringing in your ears  Nausea
uterotonic effects hepatic and renal function. Skin rush it is important to note for
 Vomiting the changes that may
that shortens the Hypersensitivity of ergot Stuffy nose
 Convulsion indicate hemorrhage. And
third stage of labor alkaloids. unpleasant taste in
and reduce blood your mouth  Sweating immediately report any
loss.  Chest pain recognized abnormality.
Classification  Hypotension
Ergot alkaloids Rare: Assessment of fundal tone,
 Bradycardia assess and document contractions, and
 Tachycardia fundal tone, non-phasic cramping help to identify
 Palpitations contractions and check and abnormality occur
 Arterial spasm contractions. during 3rd stage of labor.
Very rare:
Indication Nausea, vomiting,
Active management of  Anaphylactic
Assess for ergotism weakness, muscular pain,
third stage of labor, reaction
(overdose). insensitivity to cold and
interior hemorrhage  Hallucinations paresthesia to determine
following separation of  Myocardial dose adjustment or drug
placenta and uterine infractions withdrawal.
atony, subinvolution of  Arteriospasm
puerperal uterus, coronary Administration of this
iochiometra, caesarian  Thrombophlebitis drug therapy may alter
section, menorrhagia,  Nasal congestion Monitor prolactin levels breast milk production.
and assess for decreased
metrorrhagia, post-  Diarrhea breast milk production.
partum and post-abortal  Muscle cramp Educating the patient is
uterine bleeding. Assess patient’s and important to have a good
family’s knowledge of communication for
drug therapy. administering drug therapy
and lessen the anxiety.
Dosage & frequency

Tablet
Promotion of uterine
involution: 1 tablet
3x/day for 3-5 days.

Puerperal bleeding
subinvolution,
iochiometra, functional
uterine bleeding: 1-2
tablet3x/day.

Ampule
Active management of
3rd stage of labor: 100-
200 mcg slow IV.

Uterine
atony/hemorrhage: 200
mcg IM or 100-200
mcg slow IV. Maybe
repeated every 2-4 hrs,
if necessary up to 5
doses w/in 24 hours.

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