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    Clinical Trial Ofaloe Vera Linn. Fortfeatment of Minor Burns

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    M Nurshaffriaal Rusdi
    This clinical trial compared the efficacy of fresh Aloe vera mucilage to silver sulfadiazine for treating minor burns. 60 patients with first or second degree burns covering less than 30% of their body surface area were randomly assigned to treatment with either Aloe vera mucilage or silver sulfadiazine applied twice daily. Results found that 40-44% of patients in both groups showed improvement by the time they left the hospital. About one-third of patients were satisfied with the topical treatment. The study concluded that Aloe vera mucilage is an effective and safe option for treating minor burns.

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    © All Rights Reserved
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    Clinical Trial Ofaloe Vera Linn. Fortfeatment of Minor Burns

    Uploaded by

    M Nurshaffriaal Rusdi
    88 views4 pages
    This clinical trial compared the efficacy of fresh Aloe vera mucilage to silver sulfadiazine for treating minor burns. 60 patients with first or second degree burns covering less than 30% of their body surface area were randomly assigned to treatment with either Aloe vera mucilage or silver sulfadiazine applied twice daily. Results found that 40-44% of patients in both groups showed improvement by the time they left the hospital. About one-third of patients were satisfied with the topical treatment. The study concluded that Aloe vera mucilage is an effective and safe option for treating minor burns.

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    This clinical trial compared the efficacy of fresh Aloe vera mucilage to silver sulfadiazine for treating minor burns. 60 patients with first or second degree burns covering less than 30% of their body surface area were randomly assigned to treatment with either Aloe vera mucilage or silver sulfadiazine applied twice daily. Results found that 40-44% of patients in both groups showed improvement by the time they left the hospital. About one-third of patients were satisfied with the topical treatment. The study concluded that Aloe vera mucilage is an effective and safe option for treating minor burns.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    88 views4 pages

    Clinical Trial Ofaloe Vera Linn. Fortfeatment of Minor Burns

    Uploaded by

    M Nurshaffriaal Rusdi
    This clinical trial compared the efficacy of fresh Aloe vera mucilage to silver sulfadiazine for treating minor burns. 60 patients with first or second degree burns covering less than 30% of their body surface area were randomly assigned to treatment with either Aloe vera mucilage or silver sulfadiazine applied twice daily. Results found that 40-44% of patients in both groups showed improvement by the time they left the hospital. About one-third of patients were satisfied with the topical treatment. The study concluded that Aloe vera mucilage is an effective and safe option for treating minor burns.

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    Clinical Trial ofAloe veraLinn.

    forTfeatment of Minor Burns


    visanDTharnlikitkllM.D..
    Nuntavln Bunyrpr.phrtsaro Ph.D."
    WacharaRievpaiboon M.D.*1*
    Saho.hdiTheerapong M D '**'
    chamschlntmknt M.D.****
    TasnecThrndvensus.n B.Sc.(Pharm).*"
    sund Ninitnon****
    SuriyaWongkonkatrpe M,D,'
    ArlhornRiewDatboon M.S..(l!hu.n)**
    E.nsID. Tenambergen M.D."

    i:iin;{alodrNi8 il!.#ilnsarfl nn'ideazn.


    ilnt "!in.'ta nr.', ftni! rtfl'J:dir J.o.-, inr idmtad (!.*., fl!'ir in# a.!.
    {q, ii. 0'!,tw0a fl.!.**, iin,j,6*qm$ ,.u.*-, qnd nnmfi n. inmn,j-*,
    q6uean iur nr.'. on lislir ,.r,-, ftd lrsdcam M.L '
    'irei'drqdimi nwoM0finf,iii'nmlr lioamlsrdti lir3noaiutiii *'Ir
    l0r!, i',tui?. rwrhli **lnn!,! jd!, r. xi:nlrrlrr 'i'u0rxriri. i.lo!tr'ili
    "Iimfia'I60N nn. Jirn*nnlfdNnrilmfli4
    rhdtrr ba.ai d.:."--."b.
    ldii!nl::iniiii0i0rJld;o'doa!ornwxw'r'dr iriihLHiLllnr'tiiolmi'fitun0!t1
    "'N- -r6&-'ft l!{t|I .a t0. dn 0riiurn'!d0!iiinrh'ni;ii6 uA:nmon0tnM0rim1[.

    rFuqttt 't Mtti.rE si, inj Hospnal, Mohidat u'iv.'it! ttdrtlak taTaai $ra.tt t al PhatDq!, Mahibl
    Ar@ &tu Linn. for Minor Bumg
    'so'lh*d v, * d:

    A/r. rd,? Linn. is a nedicin plmtcrsily PATIENTSAND METHODS


    grownthoughoutThailand.lrs lcavcscotrtaiD A Dulricenrersud! of therwopreprralions
    glycoprctcinsidentifiedasalstinA orkctinP for tedtins buds wdr codductedin TungSong
    2 shich pose$ he.lin! and dti-inflammdory andPhonHospiFhin 1933.Patie$of ary age
    popcnies.: OD€nclinicd tiah obsenedrhrt *ere includedin rhesudy inheJ hadihemal fiBr
    lFsh mucil4e, cfads or Eeh preparedfom or sccond-dcgrcc burnsov$ atrarcaol lcasthan
    Aloer.raLinn. leaves*efteffecliveinrcdint 30pcrcenrof rhcbodysurfacc.m (BsA) wirhin
    ddiationbums,:I chroniculcen.a5vimi Dd lung8l 24houBot Mmi:sionandhadnotyerHeived
    skininfectiont md rhemrl buns.arAcurerox- myan.ibioricsortopical rrcdmctrt.Prricnbwirh
    icity sudy ot,,1/ocrd,? Lin.. muciiageon mbbit diftets nrellirus or rhos in r moribund nale
    skin showedno reacrionforlD 10?6houN follDw- wciccxcludcd.EliSiblcpariens wce designated
    nrucilage or silver
    rhe objective or fi€ $udy w$ to le$ the sulfddiMine lor ropic rftrlmentof ften bunr
    em.c, afftcsh mucilageolA/.d '?,? Linn for by sbdilled mndoniatrn skdion brkd on
    the ropicd redncnr of bums cmpared widr .wo progio$ic facton.namelyt'e del)thandrhe
    sizeof thelesions. Thcropicdlnedicrl ionswere

    'rhdn4t b,...4t1.,8otr "p,!4p.d'di . L et|itio,t P .4.0s.h. t.t.-.,24.,.3


    ii d-. N"nild, nqMrf,! sdad

    RESULTS
    +pliedtwiceddilyutrriltheburnshealed dr thc
    parienthadto leavetnehosprial.Eeb pa.ientsas Thi yaighr parient sere includedin rhe
    a$e$eddaily for hcaline,sideellecb dd raris- iudy,20of$emrceivingn/,e'.,?Linn. Du'
    frction with the tEtumot. A/re r.ra muciloge cilasedd 13silv$ sulfadiuine, The brselin€
    ws 6esh! pftpr€d in ! scriesor deps. Atter chmade sticsol rhepatienrswerenor sicnifi-
    wahinS rheleavessirh clem {arcr, rhcywere canrly differenl lor ei.hcr CDry, es showni.
    immssdinal%-lysolor39o savlonsolionfo TobleL Mo$ ofthe p.rien6in bo.hConpswere
    l0 nindff wnhfte oten surfacerEins upwards curcdorimpovedonrhedayrheybnhospirolas
    ab.vc dre level of 6e atisepric solurio!. The shownin Table2. Noneofnre patienarequned
    leavesweF w.shcdagair with cleanwaterand skin gruitine. Thesideeffecrof locd idolion
    thcour$ pansof ihe lerverwerepoclcdolt The wasfoundin4G44tercer.of lheparienh.About
    mucihge w$ rhen squead ihmugh $elile one.hnd of the pnrienb were sarisfied
    wirh rhe
    ropicalhhenr theyreceivcd.
    The d a wcre collded and s'bd rs'l
    monrhlyb $e pincip invc$igltorat sirirqj Drsc!ssIoN
    Hospihl. The$aristicalherhodsuscdfo' dara The imemionof rhh studymr ro isr the
    D,1y$s*crcdcsdp.ivesbiisrics,Chisqunreor efiicacymd feasi6ili(tof usingA/.. vdrdLinn.
    Fisherexei red andStudemcBr, wherelppo mucilrycfor rhetopicallearmenrof minorbuhs
    whichpeoplecouldmdna8s d homcby then

    rorri,l .pithdiotiat i, n t'i't1 ltu! 4ntuN tin*

    tih I ht ht1 t hm ir
    tior it tt. haa a hnll
    sclvcs. Ir hquiledilticullo keepruchpalenrs whichrenoieffecriveagrinsrs zo&IorGram,
    inrhehospirdfordrilyobsedionbedNesonc ncedrivcods,which arc,rhcmoscommoncdos
    do nor sanr !o b6adnnrcd o. sonrel,orpnak of burn i ecrions. Althousblocal sideeftics
    ftlnse to prdicipare bectusBrhde de no bcds wcrccommonlyobscncd,itwouldbsdifiicun b
    available rorsuchpatienhwhomthey*ould rEd dilrerenhareb€twenrhebuninssensalio. pr
    in clinical pricri.e d oulprricn6. Thqcforc, lhc ricnhcxpcicnccd ahs lnc bpicalrgcntswcrc
    numberof p ient in eNhSroup*.s sm.l1and applicdas bcing. rcsulrof thc ropicrli8cnt
    thn could be a lactor ofuccountins for thc lrck of causinsirilation or rhenechrnicalacrionof
    significanr diffcrcncc bctscer rhe rwo groups. cnrne lnenriorion,
    applicrtion
    From 40 to 4-,1per cenr of the Dalionb showcd
    imprcvemenrun ro rhe dry they leri rhe hospitd CONCLUSION
    anditi: sp*uldsd rhatne yaUofrhenwould ft h suggcscd rlErmu.ilagcotA/a,rz
    bc rordly curcd cve..!ally, Linn.,il appropiaklyprepred.i\ ennciiveand
    .csdrcofrhcrmrmcnr qasjudgedrobe 33-95 sl6 ior $e ropic'rrrer.men.
    ofminorbunr.
    per cenr. Moi of rhe pdient *ho wsE not
    impored sere tho\e *ho had the bums terted ACXNOWLEDGEMENT
    foi only lcw days. Theaurhon*ouldl,kerorhrkMs.sukan),!
    b€Neen the anribiolic rreatmentMd rhe nte of ClraDboof
    chauylorprcp.rin8rhcmmusdipl
    md
    hcalingoriffec.io.of lheburnr. Nedlylll tl,e rheGemdnAlency lor TechnicdCoopemti.n
    Dtibioricsusedwert ponicillinV or.npicillin (CTZ)fo' ruMine.lrc$udy.

    L nxtno{inr r:iw'drnrdii lnriiu !!nid.


    i'rlJnu{4!l1, n$ni{ mrli rrlli brLd,"l

    li!|'u 1|a!,]tni!6:i0:. m$i.oiiirnd!


    nxsaibmriiDr uiltlln n:!*i,irir n1l]:!-
    xMnio!rii!irdnniffi nallll5nmrmr5i-
    3 turr n::Tli'ui:i!:. nwri::'i: n:fourriri! flrrilN1i!fiildasiiirdnin{a!. ini'r
    trr:DrmiMniini. adndNnl'i!ndrqdi.
    ln rd!rlxr-r :drn!{!{d!r!li!ar!na irnto4x r:ininrino4! bdoo:drd.
    nidrid'iot6'li ;rnin!i!:n"!inni'to{i 6
    Lt8flu d,nNrrli"iJr:nr6r:flnx narr$r

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