Cancer of Larynx
Cancer of Larynx
Cancer of Larynx
Definition
Also known as laryngeal carcinoma
Inner walls of larynx are linned with squamous cells all laryngeal cancer
begins in these cells.
It occurs in all parts of larynx (Glottis, Supraglottis, Subglottis)
Also metastasize to adjacent structures as lymph nodes, head neck trachea
and more distantly through blood stream.
Risk Factors
Age mostly above 55years
Gender more prone mens
Race Africans or american
Smoking
History of head and neck cancer
Occupation exposure to asbestos, sulfuric acid
Clinical Manifestation
Voice changes (hoarseness)
Pain
Hemoptysis
Dsyphagia
Odophagia (Painful Swallowing)
Hot Potato voice
Ear pain
Stridor
Dysphonia
Diagnostic Evaluation
Indirect laryngoscopy with small mirror check for abnormal areas, vocal cords.
Direct laryngoscopy with lighted tube laryngoscope.
Endoscopy with endoscope also tissue samples and lymphnodes may be taken
biopsy.
CT Scan and MRI for tumors in larynx and others areas in neck
Biopsy tissue sample is removed to check it under microscope for cancer cells.
Barium swallow
Management
The treatment depends on size, location, type and stage of the tumor.
Cancer may be treated with radiation therapy, chemotherapy, surgery alone or in
combination
Radiation therapy
It uses the high energy X-rays or other radiation rays to kill cancer cells.
The rays are aimed at the tumor site and tissue around.
It is given 5 days a week for 5-8 weeks
It can be given in combination with surgery or chemotherapy.
It can be alone used for small tumors
It can be used with surgery the tumor will be shrinked and then the
reminants will be removed.
Surgery
Supraglottic laryngectomy
Hemilaryngectomy
Partial laryngectomy
Total laryngectomy
Coredectomy
Thyroidectomy
Supraglottic laryngectomy
It is done in early supraglottic and stage II.
The hyoid bone, glottis, and false cords are removed.
Hemilaryngectomy
It is performed when tumor extends beyond vocal cords but its size is less than
1cm.
It saves voice.
Partial laryngectomy
It performed in early stage in glottic area when only one vocal cord is
involved
It helps the patient to talk
Total laryngectomy
The laryngeal structures are removed including the hyoid bone, epiglottis,
cricoid cartilage, and two or three rings of the trachea.
There will be permanent loss of the voice and change in airway.
Tracheostomy tube may be placed.
Cordectomy removal of vocal cords only.
Thyroidectomy the removal of all parts of the thyroid gland.
Also laser beam can be used as knife to cut or remove the tumor.
Chemotherapy it is a cancer treatment that uses drugs to stop growth of cancer
cells either by killing or by stopping them from dividing.
Drugs can be injected to bloodstream.