Gujarat Technological University: W.E.F. AY 2017-18
Gujarat Technological University: W.E.F. AY 2017-18
Bachelor of Pharmacy
Subject Code: BP704TT
SEMESTER: VII
Subject Name: NOVEL DRUG DELIVERY SYSTEMS
Scope: This subject is designed to impart basic knowledge on the area of novel drug delivery systems.
Sr No Topics %
weightage
1. Controlled drug delivery systems: Introduction, terminology/definitions and 10
rationale, advantages, disadvantages, selection of drug candidates.Approaches
to design controlled release formulations based on diffusion, dissolution and ion
exchange principles. Physicochemical and biological properties of drugs
relevant to controlled release formulations
Polymers: Introduction, classification, properties, advantages and application
of polymers in formulation of controlled release drug delivery systems.
2. Microencapsulation: Definition, advantages and disadvantages, microspheres 10
/microcapsules, microparticles, methods of microencapsulation, applications
Mucosal Drug Delivery system: Introduction, Principles of bioadhesion /
mucoadhesion, concepts, advantages and disadvantages, transmucosal
permeability and formulation considerations of buccal delivery systems
Implantable Drug Delivery Systems:Introduction, advantages and
disadvantages, concept of implantsand osmotic pump
3. Transdermal Drug Delivery Systems: Introduction, Permeation through skin, 10
factors affecting permeation, permeation enhancers, basic components of
TDDS, formulation approaches
Gastroretentive drug delivery systems: Introduction, advantages,
disadvantages, approaches for GRDDS – Floating, high density systems,
inflatable and gastroadhesive systems and their applications
Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary
routes of drug delivery, Formulation of Inhalers (dry powder and metered dose),
nasal sprays, nebulizers
Targeted drug Delivery: Concepts and approaches advantages and 8
4. disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal
antibodies and their applications
5. Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods 7
to overcome –Preliminary study, ocular formulations and ocuserts
Intrauterine Drug Delivery Systems: Introduction, advantages and
disadvantages, development of intra uterine devices (IUDs) and applications
Page 1 of 2
w.e.f. AY 2017-18
GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP704TT
Recommended Books (Latest Editions)
1. Y W. Chien, Novel Drug Delivery Systems, 2nd edition, revised and expanded, Marcel Dekker, Inc.,
New York, 1992.
2. Robinson, J. R., Lee V. H. L, Controlled Drug Delivery Systems, Marcel Dekker, Inc., New York,
1992.
3. Encyclopedia of Controlled Delivery. Edith Mathiowitz, Published by Wiley Interscience Publication,
John Wiley and Sons, Inc, New York. Chichester/Weinheim
4. N.K. Jain, Controlled and Novel Drug Delivery, CBS Publishers & Distributors, New Delhi, First
edition 1997 (reprint in 2001).
5. S.P. Vyas and R.K. Khar, Controlled Drug Delivery -concepts and advances, Vallabh Prakashan, New
Delhi, First edition 2002.
Journals
1. Indian Journal of Pharmaceutical Sciences (IPA)
2. Indian Drugs (IDMA)
3. Journal of Controlled Release (Elsevier Sciences)
4. Drug Development and Industrial Pharmacy (Marcel & Decker)
5. International Journal of Pharmaceutics (Elsevier Sciences)
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w.e.f. AY 2017-18