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    DDS - MPH102T Syllabus

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    Kanisha Ranpariya

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    DDS - MPH102T Syllabus

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    Kanisha Ranpariya
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    4 views2 pages

    DDS - MPH102T Syllabus

    Uploaded by

    Kanisha Ranpariya

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    © All Rights Reserved
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    GUJARAT TECHNOLOGICAL UNIVERSITY

    M.Pharm
    PHARMACEUTICS
    SEMESTER: I

    Subject Name: DRUG DELIVERY SYSTEMS


    Subject Code: MPH102T

    SCOPE: This course is designed to impart knowledge on the area of advances in novel drug delivery
    systems

    OBJECTIVES: Upon completion of the course, student shall be able to understand


    1. The various approaches for development of novel drug delivery systems.
    2. The criteria for selection of drugs and polymers for the development of delivering system
    3. The formulation and evaluation of Novel drug delivery systems.

    Sr.No Course content Total Hrs


    1. Sustained Release(SR) and Controlled Release (CR) formulations: 10
    Introduction & basic concepts, advantages/ disadvantages, factors
    influencing, Physicochemical & biological approaches for SR/CR
    formulation, Mechanism of Drug Delivery from SR/CR formulation.
    Polymers: introduction, definition, classification, properties and application
    Dosage Forms for Personalized Medicine: Introduction, Definition,
    Pharmacogenetics, Categories of Patients for Personalized Medicines:
    Customized drug delivery systems, Bioelectronic Medicines, 3D printing of
    pharmaceuticals, Telepharmacy.
    2. Rate Controlled Drug Delivery Systems: Principles & Fundamentals, Types, 10
    Activation; Modulated Drug Delivery Systems;Mechanically activated, pH
    activated, Enzyme activated, and Osmotic activated Drug Delivery Systems
    Feedback regulated Drug Delivery Systems; Principles & Fundamentals
    3. Gastro-Retentive Drug Delivery Systems: Principle, concepts advantages 10
    and disadvantages, Modulation of GI transit time approaches to extend GI
    transit. Buccal Drug Delivery Systems: Principle of muco adhesion,
    advantages and disadvantages, Mechanism of drug permeation, Methods of
    formulation and its evaluations.
    4. Occular Drug Delivery Systems: Barriers of drug permeation, Methods to 6
    overcome barriers.
    5. Transdermal Drug Delivery Systems: Structure of skin and barriers, 10
    Penetration enhancers, Transdermal Drug Delivery Systems, Formulation
    and evaluation
    6 Protein and Peptide Delivery: Barriers for protein delivery. Formulation and 8
    Evaluation of delivery systems of proteins and other macromolecules.
    7 Vaccine delivery systems: Vaccines, uptake of antigens, single shot 6
    vaccines, mucosal and transdermal delivery of vaccines.

    REFERENCES:
    1. Y W. Chien, Novel Drug Delivery Systems, 2nd edition, revised and expanded, Marcel Dekker,
    Inc., New York, 1992.
    2. Robinson, J. R., Lee V. H. L, Controlled Drug Delivery Systems, Marcel Dekker,Inc., New York,
    1992.
    3. Encyclopedia of controlled delivery, Editor- Edith Mathiowitz, Published by WileyInterscience
    Publication, John Wiley and Sons, Inc, New York! Chichester/Weinheim
    4. N.K. Jain, Controlled and Novel Drug Delivery, CBS Publishers & Distributors, New Delhi, First
    edition 1997 (reprint in 2001).
    5. S.P.Vyas and R.K.Khar, Controlled Drug Delivery - concepts and advances, Vallabh Prakashan,
    New Delhi, First edition 2002

    JOURNALS:
    1. Indian Journal of Pharmaceutical Sciences (IPA)
    2. Indian drugs (IDMA)
    3. Journal of controlled release (Elsevier Sciences) desirable
    4. Drug Development and Industrial Pharmacy (Marcel & Decker) desirable

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