1. Pharmacology mnemonics provide concise summaries of drug mechanisms, indications, side effects and interactions through the use of memorable acronyms and phrases.
2. The document lists over 30 mnemonics summarizing information on drug classes like antihypertensives, antidepressants, antibiotics, cancer drugs and more.
3. The mnemonics concisely summarize essential information on drug mechanisms, members of each class, clinical uses and adverse effects through creative wordplay and acronyms to aid in memorization and recall of pharmacology concepts.
1. Pharmacology mnemonics provide concise summaries of drug mechanisms, indications, side effects and interactions through the use of memorable acronyms and phrases.
2. The document lists over 30 mnemonics summarizing information on drug classes like antihypertensives, antidepressants, antibiotics, cancer drugs and more.
3. The mnemonics concisely summarize essential information on drug mechanisms, members of each class, clinical uses and adverse effects through creative wordplay and acronyms to aid in memorization and recall of pharmacology concepts.
1. Pharmacology mnemonics provide concise summaries of drug mechanisms, indications, side effects and interactions through the use of memorable acronyms and phrases.
2. The document lists over 30 mnemonics summarizing information on drug classes like antihypertensives, antidepressants, antibiotics, cancer drugs and more.
3. The mnemonics concisely summarize essential information on drug mechanisms, members of each class, clinical uses and adverse effects through creative wordplay and acronyms to aid in memorization and recall of pharmacology concepts.
1. Pharmacology mnemonics provide concise summaries of drug mechanisms, indications, side effects and interactions through the use of memorable acronyms and phrases.
2. The document lists over 30 mnemonics summarizing information on drug classes like antihypertensives, antidepressants, antibiotics, cancer drugs and more.
3. The mnemonics concisely summarize essential information on drug mechanisms, members of each class, clinical uses and adverse effects through creative wordplay and acronyms to aid in memorization and recall of pharmacology concepts.
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The document provides various mnemonics to help remember characteristics of different drug classes, their mechanisms, side effects, and other important information.
Mnemonics are provided for pharmacology topics like drug classes (sulfonamides, diuretics, tuberculosis treatment), mechanisms (guanethidine), administration procedures (insulin mixing), and more.
Major side effects discussed include those for corticosteroids (CUSHING BAD MD), lithium (LITH), sodium valproate (VALPROATE), nitrofurantoin, methyldopa, and more.
Pharmacology Mnemonics Mechanism of resistance are Modifying
1. Sulfonamides: common characteristics enzymes
SULFA: Inhibit protein synthesis by binding to 30S S-Steven-Johnson syndrome/ Skin rash / subunit Solubility low Nephrotoxic U-Urine precipitation/ Useful for UTI Ototoxic L-Large spectrum (gram positives and 5. Cocaine: cardiovascular effect COcaine negatives) causes blood F-Folic acids synthesis blocker (as well as vessels to COnstrict (unlike other local synthesis of nucleic acids) anesthetics which cause vasodilation). A-Analog of PABA
6. Thalidomide: effect on cancer cells
2. Diuretics: groups “Leak Over The CAN“: “Thalidomide L-Loop diuretics makes the blood vessels hide“: O-Osmotics Use thalidomide to stop cancer cells from T-Thiazides growing new blood vessels. C-Carbonic anhydrase inhibitors A-Aldosterone inhibitors 7. Carbamazepine (CBZ): use CBZ: N-Na (sodium) channel blockers C-Cranial Nerve V (trigeminal) neuralgia B-Bipolar disorder 3. Tuberculosis: treatment If you forget Z-Zeisures your TB drugs, you’ll die and might need a PRIEST“: 8. Warfarin: interactions ACADEMIC P-Pyrazinamide QACS: R-Rifampin A-Amiodarone I-Isoniazid (INH) C-Cimetidine E-Ethambutol A-Aspirin St-Streptomycin D-Dapsone E-Erythromycin 4. Aminoglycosides: common M-Metronidazole characteristics AMINO: I-Indomethacin Active Against Aerobic gram negative C-Clofibrates G-Gain weight Q-Quinidine S-Striae A-Azapropazone B-Bone loss (osteoporosis) C-Ciprofloxacin A-Acne S-Statins D-Diabetes M-Myopathy, moon faces 9. Morphine: side-effects MORPHINE: D-Depression and emotional changes M-Myosis O-Out of it (sedation) 12. Microtubules: drugs that act on R-Respiratory depression microtubules. “The P-Pneumonia (aspiration) MicroTubule Growth Voiding Chemicals”: H-Hypotension T-Thiabendazole I-Infrequency (constipation, urinary M-Mebendazole retention) T-Taxol N-Nausea G-Griseofulvin E-Emesis V-Vincristine/ Vinblastine C-Colchicine 10. Tricyclic antidepressants (TCA): side BromoCRYPTine is a DOPamine agonist. effects TCA’S: T-Thrombocytopenia 13. Beta blockers: members “The NEPAL C-Cardiac (arrhythmia, MI, stroke) Prime A-Anticholinergic (tachycardia, urinary M-Minister”: retention, etc) T-Timolol S-Seizures N-Nadolol 11. Corticosteroids: adverse side effects E-Esmolol CUSHINGS BAD MD: P-Pindolol C-Cataracts A-Atenolol U-Up all night (sleep disturbances) L-Labetalol S-Suppression of HPA axis P-Propranolol H-Hypertension/ buffalo Hump M-Metoprolol I-Infections N-Necrosis (avascular) 14. Guanethidine: mechanism M-Miosis GuaNEthidine prevents NE (norepinephrine) D-Dependency release. C-Constipation A-Analgesics 15. Insulin: mixing regular insulin and R-Respiratory depression NPH “Not Ready, E-Euphoria Ready Now”: S-Sedation Air into NPH Air into Regular 19. Adrenoceptors: vasomotor function of Draw up Regular alpha vs. beta ABCD: Draw up NPH Alpha = Constrict. Beta = Dilate. 16. Parasympathetic vs. sympathetic neurotransmitters “No sympathy for a Pair 20. Atropine use: tachycardia or of Aces”: bradycardia “A goes with B“: Norepinephren is secreted in by the Atropine used clinically to treat Sympathetic nervous system Bradycardia. while Acetylcholine is secreted in the 21. Beta 1 selective blockers “BEAM ONE Parasympathetic nervous up, Scotty”: system. Beta 1 blockers: E-Esmolol 17. Benzodiazepines: 3 members that A-Atenolol undergo extrahepatic metabolism M-Metropolol “Outside The Liver”: O-Oxazepam 22. Cancer drugs: time of action between T-Temazepam DNA->mRNA ABCDEF: L-Lorazepam A-Alkylating agents These undergo extrahepatic metabolism and B-Bleomycin do not form active metabolites. C-Cisplastin D-Dactinomycin/ Doxorubicin 18. Opiods: mu receptor effects “MD E-Etoposide CARES“: F-Flutamide and other steroids or their 27. Propranolol and related ‘-olol’ drugs: antagonists (eg tamoxifen, leuprolide) usage “olol” is just two backwards lower case b’s. 23. Busulfan: features ABCDEF: Backward b’s stand for “beta blocker”. Beta A-Alkylating agent blockers include acebutolol, betaxolol, B-Bone marrow suppression s/e bisoprolol, oxprenolol, propranolol C-CML indication D-Dark skin (hyperpigmentation) s/e 28. Beta blockers: B1 selective vs. B1-B2 E-Endrocrine insufficiency (adrenal) s/e non-selective A F-Fibrosis (pulmonary) s/e through N: B1 selective: Acebutalol, Atenolol, Esmolol, Metoprolol. 24. Tricyclic antidepressants: members O through Z: B1, B2 non-selective:Pindolol, worth knowing “I have to Propanalol, Timolol. hide, the CIA is after me”: C-Clomipramine 29. Antirheumatic agents (disease I-Imipramine modifying): members CHAMP: A-Amitrptyline C-Cyclophosphamide H-Hydroxycloroquine and choloroquinine 25. Torsades de Pointes: drugs causing A-Auranofin and other gold compounds APACHE: M-Methotrexate A-Amiodarone P-Penicillamine P-Procainamide A-Arsenium 30. HMG-CoA reductase inhibitors C-Cisapride (statins): side effects, H-Haloperidol contraindications, interactions HMG–CoA: E-Eritromycin · Side effects: H-Hepatotoxicity 26. Asthma drugs: leukotriene inhibitor M-Myositis [aka rhabdomyolysis] action zAfirlukast: · Contraindications: Antagonist of lipoxygenase zIlueton: G-Girl during pregnancy/ Growing children Inhibitor of LT receptor · Interactions: C-Coumarin/ Cyclosporine 31. Serotonin syndrome: components 36. Ribavirin: indications RIBAvirin: Causes HARM: R-RSV H-Hyperthermia I-Influenza B A-Autonomic instability (delirium) A-Arenaviruses (Lassa, Bolivian, etc.) R-Rigidity 37. SIADH-inducing drugs ABCD: M-Myoclonus A-Analgesics: opioids, NSAIDs 32. Therapeutic index: formula TILE: B-Barbiturates TI = LD50 / ED50 C-Cyclophosphamide/ Chlorpromazine/ Carbamazepine 33. Antiarrhythmics: class III members D-Diuretic (thiazide) BIAS: B-Bretylium 38. Diuretics: thiazides: indications “CHIC I-Ibutilide to use A-Amiodarone thiazides”: S-Sotalol C-CHF H-Hypertension 34. MAOIs: indications MAOI‘S: I-Insipidous M-Melancholic [classic name for atypical C-Calcium calculi depression] A-Anxiety 39. Parkinsonism: drugs SALAD: O-Obesity disorders [anorexia, bulemia] S-Selegiline I-Imagined illnesses [hypochondria] A-Anticholinenergics (trihexyphenidyl, S-Social phobias benzhexol, ophenadrine) L-L-Dopa + peripheral decarboxylase 35. K+ increasing agents K-BANK: inhibitor (carbidopa, benserazide) K-K-sparing diuretic A-Amantadine B-Beta blocker D-Dopamine postsynaptic receptor agonists A-ACEI (bromocriptine, lisuride, pergolide) N-NSAID K-Ksupplement 40. Thrombolytic agents USA: U-Urokinase S-Streptokinase M-Membrane stabilizers (class I) A-Alteplase (tPA) B-Beta blockers A-Action potential widening agents 41. Morphine: effects at mu receptor C-Calcium channel blockers PEAR: P-Physical dependence 45. Teratogenic drugs “W/ E-Euphoria TERATOgenic”: A-Analgesia W-Warfarin R-Respiratory depression T-Thalidomide E-Epileptic drugs: phenytoin, valproate, 42. Morphine: effects MORPHINES: carbamazepine M-Miosis R-Retinoid O-Orthostatic hypotension A-ACE inhibitor R-Respiratory depression T-Third element: lithium P-Pain supression O-OCP and other hormones (eg danazol) H-Histamine release/ Hormonal alterations I-Increased ICT 46. Epilepsy types, drugs of choice N-Nausea “Military General Attacked Weary E-Euphoria Fighters Pronouncing ‘Veni Vedi Veci’ S-Sedation After Crushing Enemies”: ·Epilepsy types: 43. Anticholinergic side effects “Know the M-Myoclonic ABCD’S of anticholinergic side effects”: G-Grand mal A-Anorexia A-Atonic B-Blurry vision W-West syndrome D-Constipation/ Confusion F-Focal D-Dry Mouth P-Petit mal (absence) D-Sedation/ Stasis of urine · Respective drugsy: V-Valproate 44. Antiarrhythmics: classification I to IV V-Valproate MBA College VValproate · In order of class I to IV: A-ACTH C-Carbamazepine 51. Vigabatrin: mechanism Vi-GABA– E-Ethosuximide Tr–In: 47. Pulmonary infiltrations inducing Via GABA Transferase Inhibition drugs “Go BAN Me!”: 52. Propythiouracil (PTU): mechanism It Go-Gold inhibits PTU: B-Bleomycin/ Busulphan/ BCNU P-Peroxidase/ Peripheral deiodination A-Amiodarone/ Acyclovir/ Azathioprine T-Tyrosine iodination N-Nitrofurantoin U-Union (coupling) M-Melphalan/ Methotrexate/ Methysergide
53. Beta-blockers: nonselective beta-
48. Respiratory depression inducing blockers “Tim Pinches His Nasal drugs “STOP Problem” (because he has a runny breathing”: nose…): S-Sedatives and hypnotics Tim-Timolol T-Trimethoprim Pin-Pindolol O-Opiates His-Hismolol P-Polymyxins Na-Naldolol 49. Benzodiazapines: ones not Pro-Propranolol metabolized by the liver (safe to use in 54. Enoxaparin (prototype low molecular liver failure) LOT: weight heparin): action, monitoring L-Lorazepam EnoXaprin only acts on factor Xa. O-Oxazepam Monitor Xaconcentration, rather than APTT. T-Temazepam
S-Salivation/ Secretions/ Sweating DISCOS: L-Lacrimation D-Digoxin U-Urination I-Isoniazid G-Gastrointestinal upset S-Spironolactone B-Bradycardia/ Bronchoconstriction/ Bowel C-Cimetidine movement O-Oestrogens A-Abdominal cramps/ Anorexia S-Stilboestrol M-Miosis 60. Amiodarone: action, side effects 6 P’s: 57. Hypertension: treatment ABCD: P-Prolongs action potential duration ACE inhibitors/ AngII antagonists P-Photosensitivity (sometimes Alpha agonists P-Pigmentation of skin also) P-Peripheral neuropathy B-Beta blockers PPulmonary alveolitis and fibrosis C-Calcium antagonists P-Peripheral conversion of T4 to T3 is D-Diuretics (sometimes vasoDilators also) inhibited -> hypothyroidis
58. Phenytoin: adverse effects 61. Beta blockers with intrinsic
PHENYTOIN: sympathomimetic activity P-P-450 interactions Picture diabetic and asthmatic kids riding H-Hirsutism away on a cart that rolls on pinwheels. EEnlarged gums Pindolol and Carteolol have high and N-Nystagmus moderate ISA respectively, making them Y-Yellow-browning of skin acceptable for use in some diabetics or T-Teratogenicity asthmatics even though they are non-seletive O-Osteomalacia beta blockers. I-Interference with B12 metabolism (hence 62. Monoamine oxidase inhibitors: T-Testicular carcinoma members “PIT of despair”: O-Oat cell carcinoma of lung P-Phenelzine P-Prostate carcinoma I-Isocarboxazid · Side effect: T-Tranylcypromine Affects TOP of your head, causing alopecia A pit of despair, since MAOs treat 66. Antimuscarinics: members, action depression. “Inhibits Parasympathetic And Sweat”: 63. Physostigmine vs. neostigmine I-Ipratropium LMNOP: P-Pirenzepine L-Lipid soluble A-Atropine M-Miotic S-Scopolamine N-Natural · Muscarinic receptors at all parasympathetic O-Orally absorbed well endings sweat glands in P-Physostigmine sympathetic. Neostigmine, on the contrary, is: Water soluble 67. Lithium: side effects LITHIUM: Used in myesthenia gravis L-Leukocytes Increased (leukocytosis) Synthetic T-Tremors Poor oral absorption H-Hypothyroidism I-Increased Urine 64. Antibiotics contraindicated during M-Moms beware (teratogenic) pregnancy MCAT: M-Metronidazole 68. Osmotic diuretics: members GUM: C-Chloramphenicol G-Glycerol A-Aminoglycoside U-Urea T-Tetracycline M-Mannitol
65. Etoposide: action, indications, side
69. Narcotics: side effects “SCRAM if you effect “eTOPoside”: see a drug dealer”: · Action: S-Synergistic CNS depression with other Inhibits TOPoisomerase II drugs · Indications: C-Constipation A-Angina R-Respiratory depression M-Migraines A-Addiction A-Atrial flutter, fibrillation M-Miosis S-Supraventricular tachycardia H-Hypertension 70. Benzodiazepines: antidote “Ben is off with the flu“: 75. Benzodiazepenes: drugs which Benzodiazepine effects off with Flumazenil. decrease their metabolism“I‘m Overly Calm”: 71. SSRIs: side effects SSRI: I-Isoniazid S-Serotonin syndrome O-Oral contraceptive pills S-Stimulate CNS C-Cimetidine R-Reproductive disfunctions in male I-Insomnia 76. Warfarin: metabolism SLOW · Has a slow onset of action. 72. Depression: 5 drugs causing it · A quicK Vitamin K antagonist, though. PROMS: S-Small lipid-soluble molecule P-Propranolol L-Liver: site of action R-Reserpine O-Oral route of administration. O-Oral contraceptives W-Warfarin M-Methyldopa S-Steroids 77. Tetracycline: teratogenicity TEtracycline is a 73. Sex hormone drugs: male “Feminine TE-TEratogen that causes staining of TEeth Males Need Testosterone“: in the newborn. F-Fluoxymesterone M-Methyltestosterone 78. Myasthenia gravis: edrophonium vs. N-Nandrolone pyridostigmine eDrophonium Testosterone is for Diagnosis.pyRIDostigmine is to get RIDof symptoms. 74. Ca++ channel blockers: uses CA++ MASH: 79. Opioids: effects BAD AMERICANS: C-Cerebral vasospasm/ CHF B-Bradycardia & hypotension A-Anorexia 83. Direct sympathomimetic D-Diminished pupilary size catecholamines DINED: A-Analgesics D-Dopamine M-Miosis I-Isoproterenol E-Euphoria N-Norepinephrine R-Respiratory depression E-Epinephrine I-Increased smooth muscle activity (biliary D-Dobutamine tract constriction) 84. Delerium-causing drugs ACUTE C-Constipation CHANGE IN MS: A-Ameliorate cough reflex A-Antibiotics (biaxin, penicillin, N-Nausea and vomiting ciprofloxacin) S-Sedations C-Cardiac drugs (digoxin, lidocaine) 80. Narcotic antagonists The Narcotic U-Urinary incontinence drugs Antagonists (anticholinergics) are NAloxone and NAltrexone. T-Theophylline · Important clinically to treat narcotic E-Ethanol overdose. C-Corticosteroids H-H2 blockers 81. Inhalation anesthetics SHINE: A-Antiparkinsonian drugs S-Sevoflurane N-Narcotics (esp. mepridine) H-Halothane G-Geriatric psychiatric drugs I-Isoflurane E-ENT drugs N-Nitrous oxide I-Insomnia drugs E-Enflurane N-NSAIDs (eg indomethacin, naproxin) M-Muscle relaxants 82. Disulfiram-like reaction inducing S-Seizure medicines drugs “PM PMT” as in Pre Medical Test in the PM: 85. Nitrofurantoin: major side effects P-Procarbazine NitroFurAntoin: M-Metronidazole N-Neuropathy (peripheral neuropathy) PMT-Cefo (Perazone, Mandole, Tetan). F-Fibrosis (pulmonary fibrosis) H-Hypertension/ Hyperglycaemia A-Anemia (hemolytic anemia) A-Avascular necrosis of femoral head S-Skin thinning 86. Methyldopa: side effects O-Osteoporosis METHYLDOPA: N-Negative nitrogen balance M-Mental retardation E-Emotional liability E-Electrolyte imbalance T-Tolerance 89. Sodium valproate: side effects H-Headache/ Hepatotoxicity VALPROATE: psYcological upset V-Vomiting L-Lactation in female A-Alopecia D-Dry mouth L-Liver toxicity O-Oedema P-Pancreatitis/ Pancytopenia P-Parkinsonism R-Retention of fats (weight gain) A-Anaemia (haemolytic) O-Oedema (peripheral oedema) A-Appetite increase 87. Lithium: side effects LITH: T-Tremor L-Leukocytosis E-Enzyme inducer (liver) I-Insipidus [diabetes insipidus, tied to polyuria] 90. Lead poisoning: presentation T-Tremor/ Teratogenesis ABCDEFG: H-Hypothyroidism A-Anemia 88. Steroids: side effects B-Basophilic stripping BECLOMETHASONE: C-Colicky pain B-Buffalo hump D-Diarrhea E-Easy bruising E-Encephalopathy C-Cataracts F-Foot drop L-Larger appetite G-Gum (lead line) O-Obesity 91. Beta-1 vs Beta-2 receptor location M-Moonface “You have 1 heart and 2 lungs“: E-Euphoria Beta-1 are therefore primarily on heart. T-Thin arms & legs Beta-2 primarily on lungs. 95. Routes of entry: most rapid ways 92. Beta-blockers: main meds/toxins enter body “Stick it, Sniff it, contraindications, cautions ABCDE: Suck it, Soak it”: A-Asthma Stick = Injection B-Block (heart block) Sniff = inhalation C-COPD Suck = ingestion D-Diabetes mellitus Soak = absorption E-Electrolyte (hyperkalemia) 96. Ipratropium: action Atropine is 93. Metabolism enzyme inducers buried in the middle: “Randy’s Black Car iprAtropium, so it behaves like Atropine. Goes Putt Putt and Smokes“: 97. Hepatic necrosis: drugs causing focal R-Rifampin to massive necrosis “Very B-Barbiturates A-Angry Hepatocytes”: C-Carbamazepine V-Valproic acid G-Grisoefulvin A-Acetaminophen P-Phenytoin H-Halothane P-Phenobarb
98. Bleomycin: action “Bleo–Mycin Blows
94. Cholinergics (eg organophosphates): My DNA to bits”: effects If you know these, you will be Bleomycin works by fragmenting DNA “LESS DUMB“: (blowing it to bits). L-Lacrimation MyDNA signals that its used for cancer E-Excitation of nicotinic synapses (targeting self cells). S-Salivation S-Sweating 99. Beta-blockers: side effects “BBC D-Diarrhea Loses Viewers U-Urination In Rochedale”: M-Micturition B-Bradycardia B-Bronchoconstriction B-Bronchoconstriction C-Claudication L-Lipids V-Vivid dreams & nightmares I- -ve Inotropic action R-Reduced sensitivity to hypoglycaemia
100. Cisplatin: major side effect, action
“Ci-Splat–In“: Major side effect: Splat (vomiting sound)– vomiting so severe that anti-nausea drug needed. Action: Goes Into the DNA strand.