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    Upfront: Oral Hygiene Risk Factor

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    Aremi Sánchez
    The document discusses the potential connection between oral hygiene and COVID-19 complications. Poor oral hygiene is considered a risk factor as it can increase bacterial load in the mouth. Bacterial superinfections are common in severe COVID-19 cases and improved oral hygiene may help reduce complications.

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    Upfront: Oral Hygiene Risk Factor

    Uploaded by

    Aremi Sánchez
    53 views1 page
    The document discusses the potential connection between oral hygiene and COVID-19 complications. Poor oral hygiene is considered a risk factor as it can increase bacterial load in the mouth. Bacterial superinfections are common in severe COVID-19 cases and improved oral hygiene may help reduce complications.

    Original Title

    10.1038@s41415-020-1545-3

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    The document discusses the potential connection between oral hygiene and COVID-19 complications. Poor oral hygiene is considered a risk factor as it can increase bacterial load in the mouth. Bacterial superinfections are common in severe COVID-19 cases and improved oral hygiene may help reduce complications.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    53 views1 page

    Upfront: Oral Hygiene Risk Factor

    Uploaded by

    Aremi Sánchez
    The document discusses the potential connection between oral hygiene and COVID-19 complications. Poor oral hygiene is considered a risk factor as it can increase bacterial load in the mouth. Bacterial superinfections are common in severe COVID-19 cases and improved oral hygiene may help reduce complications.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    UPFRONT

    Oral hygiene risk factor 80% of patients with COVID-19 infections clear that bacterial superinfections are common
    Sir, I would like to inform readers about the have mild symptoms, 20% progress to have a in patients suffering from a severe case of
    potential connection between high bacterial severe form of infection associated with higher COVID-19.
    load in the mouth and complications levels of inflammatory markers (Interleukin V. Sampson, London, UK
    associated with COVID-19 infection. 2, 6, 10) and bacteria.2,3 They also exhibit a
    Oral hygiene should be improved during a remarkably higher neutrophil count and lower References
    COVID-19 infection in order to reduce the lymphocyte count than in mild patients.4 A 1. World Health Organization. Clinical management of severe
    acute respiratory infection when COVID-19 is suspected.
    bacterial load in the mouth and the risk of high neutrophil count is abnormal for a viral
    Interim guidance, 13 March 2020. Available at: https://
    a bacterial superinfection. We recommend infection, but common for a bacterial infection, www.who.int/publications-detail/clinical-management-of-
    that poor oral hygiene be considered a risk suggesting that in severe cases of COVID-19, severe-acute-respiratory-infection-when-novel-coronavirus-
    (ncov)-infection-is-suspected (accessed April 2020).
    to COVID-19 complications, particularly in bacterial superinfection is common. 2. Gong J. Correlation Analysis Between Disease Severity
    patients predisposed to altered biofilms due The three main comorbidities associated and Inflammation-related Parameters in Patients with
    COVID-19 Pneumonia. Tongji Hospital, 2020.
    to diabetes, hypertension or cardiovascular with an increased risk of complications from 3. Liu J. Neutrophil-to-Lymphocyte Ratio Predicts Severe
    disease. Bacteria present in patients with COVID-19 are diabetes, hypertension and Illness Patients with 2019 Novel Coronavirus. Beijing
    Ditan Hospital, 2020.
    severe COVID-19 are associated with the cardiovascular disease.5 These comorbidities are 4. Zheng M, Gao Y, Wang G et al. Functional exhaustion
    oral cavity, and improved oral hygiene may also associated with altered oral biofilms and of antiviral lymphocytes in COVID-19 patients. Cell Moll
    Immunol 2020; DOI: 10.1038/s41423-020-0402-2.
    reduce the risk of complications. Whilst periodontal disease. Periodontopathic bacteria 5. Zhou F, Yu T, Du R et al. Clinical course and risk factors
    COVID-19 has a viral origin, it is suspected are implicated in systemic inflammation, for mortality of adult inpatients with COVID-19 in
    Wuhan, China: A retrospective cohort study. Lancet
    that in severe forms of the infection, bacteraemia, and pneumonia.⁶ Bacteria present 2020; 395: 1054-1062.
    bacteria plays a part, increasing the chance in the metagenome of patients severely infected 6. Nagaoka K. Prevotella intermedia induces severe
    bacteremic pneumococcal pneumonia in mice with
    of complications such as pneumonia, acute with COVID-19 included high reads for upregulated platelet-activating factor receptor
    respiratory distress syndrome, sepsis, septic Prevotella, Staphylococcus, and Fusobacterium, expression. American Society for Microbiology, 2014.
    7. Chakraborty S. Metagenome of SARS-Cov2 patients in
    shock and death.1 all usually commensal organisms of the Shenzhen with travel to Wuhan: OSF Preprints, 2020.
    The development and severity of mouth.⁷ Over 80% of patients in ICU exhibited 8. Gautret P, Lagier J-C, Parola P et al. Hydroxychloroquine
    and azithromycin as a treatment of COVID-19: Results of an
    complications following a COVID-19 infection an exceptionally high bacterial load,³ and
    Open-Label Non-randomized trial. Int J Antimicrob Agents
    depend on numerous host and viral factors that treatment has been successful with a dual 2020; DOI: 10.1016/j.ijantimicag.2020.105949.
    will affect a patient’s immune response. Whilst regime of an antiviral and an antibiotic.⁸ It is https://doi.org/10.1038/s41415-020-1545-3

    BRITISH DENTAL JOURNAL | VOLUME 228 NO. 8 | April 24 2020 569


    © 2020 British Dental Association. All rights reserved.

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