NanoData Report
NanoData Report
Compilation
Written by the Joint Institute for Innovation Policy, Brussels, Belgium, in co-operation with
CWTS, University of Leiden, Leiden, Netherlands; Frost & Sullivan Limited, London, United Kingdom;
Joanneum Research Forschungsgesellschaft mbH, Graz, Austria; the Nanotechnology Industries
Association, Brussels, Belgium; Oakdene Hollins Limited, Aylesbury, United Kingdom; Tecnalia
Research and Innovation, Bilbao, Spain; and TNO, The Hague, Netherlands
December 2015
EUROPEAN COMMISSION
Directorate-General for Research and Innovation
Directorate Industrial Technologies
Unit D.3 - Advanced Materials and Nanotechnologies
E-mail: RTD-PUBLICATIONS@ec.europa.eu
European Commission
B-1049 Brussels
EUROPEAN COMMISSION
NanoData Landscape
Compilation
Information and Communication Technologies
Written by:
Jacqueline E M Allan
Harrie Buist
Adrian Chapman
Guillaume Flament
Christian Hartmann
Iain Jawad
Eelco Kuijpers
Hanna Kuittinen
Ed Noyons
Ankit Shukla
Annelieke van der Giessen
Alfredo Yegros
Additional contributions:
Ashfeen Aribea
Iker Barrondo Saez
Nia Bell
Unai Calvar Aranburu
Lia Federici
Robbert Fisher
Jos Leijten
Ingeborg Meier
Milica Misojcic
Freddie Ntow
Luca Remotti
Claire Stolwijk
Xabier Uriarte Olaeta
LEGAL NOTICE
This document has been prepared for the European Commission however it reflects the views only of the
authors, and the Commission cannot be held responsible for any use which may be made of the information
contained therein.
Contents
EXECUTIVE SUMMARY ..................................................................................................10
1 BACKGROUND ......................................................................................................14
2 INTRODUCTION TO ICT AND THE ROLE OF NANOTECHNOLOGY .................................15
2.1 Introduction to ICT ......................................................................................15
2.2 Role of nanotechnology in ICT .......................................................................21
3 EU POLICIES AND PROGRAMMES FOR NANOTECHNOLOGY AND ICT ...........................23
3.1 The EU Framework Programmes: supports for nanotechnology .........................23
3.2 The EU Framework Programme: funding and participation data for FP6 and FP7 ..27
3.3 Other EU policies and programmes ................................................................39
4 POLICIES AND PROGRAMMES IN MEMBER STATES FOR NANOTECHNOLOGY AND ICT ...43
5 POLICIES AND PROGRAMMES IN OTHER COUNTRIES ................................................51
5.1 Europe .......................................................................................................51
5.2 The Americas ..............................................................................................52
5.3 Asia ...........................................................................................................57
5.4 Oceania......................................................................................................67
5.5 Africa .........................................................................................................68
6 PUBLICATIONS IN ICT NANOTECHNOLOGY ..............................................................70
6.1 Overview ....................................................................................................70
6.2 Activity by region and country.......................................................................72
6.3 Activity by organisation type .........................................................................74
7 PATENTING IN ICT NANOTECHNOLOGY ...................................................................76
7.1 Overview ....................................................................................................76
7.2 Number and evolution over time of ICT nanotechnology patent families .............76
7.3 Activity by filing country and region ...............................................................77
7.4 Activity by country of applicant .....................................................................78
7.5 Patenting activity by organisation type ...........................................................84
8 INDUSTRY AND NANOTECHNOLOGY FOR ICT ...........................................................89
8.1 Overview of the ICT industry ........................................................................89
8.2 Nanotechnology in the ICT industry ...............................................................92
9 PRODUCTS AND MARKETS FOR ICT THROUGH NANOTECHNOLOGY........................... 100
9.1 Introduction.............................................................................................. 100
9.2 Global markets and forecasts for ICT products using nanotechnology ............... 100
9.3 Commercialised products for ICT through nanotechnology .............................. 102
10 THE WIDER ENVIRONMENT FOR NANOTECHNOLOGY AND ICT ................................. 131
10.1 Regulation and standards for nanotechnology ............................................... 131
10.2 Environment, health and safety and nanotechnology ..................................... 135
10.3 Communication, public attitudes and societal issues ...................................... 140
11 CONCLUDING SUMMARY ..................................................................................... 144
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NanoData – Landscape Compilation - ICT
Figures
FIGURE 3-1: FUNDING OF ICT NANOTECHNOLOGY FOR FP6 AND FP7 TOGETHER, FOR FP7 AND FOR FP6 ........ 28
FIGURE 3-2: SHARES OF EC CONTRIBUTION BY ORGANISATION TYPE FOR NANOTECHNOLOGY AND ICT .......... 32
FIGURE 3-3: PERCENTAGE SHARES OF FP FUNDING BY COUNTRY IN FP, NT AND ICT NANOTECHNOLOGY ........ 37
FIGURE 3-4: EC FUNDING FOR ICT NT ACTIVITIES IN FP6 AND FP7 IN MEUR AND COUNTRY SHARES ................ 38
FIGURE 6-1: ANNUAL NST ICT PUBLICATION OUTPUT, WORLDWIDE AND EU28&EFTA, 2000-2014 ................... 71
FIGURE 6-2: NST ICT PUBLICATIONS AS A PERCENTAGE OF NST WORLD TOTAL, 2000-2014 .............................. 71
FIGURE 6-3: NUMBER OF NST ICT PUBLICATIONS BY COUNTRY (TOP 9), 2014 ................................................... 72
FIGURE 6-4: NUMBER OF NST ICT PUBLICATIONS BY EU&EFTA COUNTRIES, 2014 ............................................. 73
FIGURE 7-1: NUMBER OF PATENT FAMILIES BY FILING AUTHORITY (PCT, EPO, AND USPTO) ............................. 77
FIGURE 7-2: EVOLUTION OVER TIME OF WIPO (PCT), EPO AND USPTO ICT NANOTECHNOLOGY PATENTING ... 77
FIGURE 7-3: NUMBER OF PATENT FAMILIES BY COUNTRY OF APPLICANT .......................................................... 80
FIGURE 7-4: NUMBER OF PATENT FAMILIES BY COUNTRY OF APPLICANT EU28/EFTA ....................................... 80
FIGURE 7-5: NUMBER OF PATENT FAMILIES BY COUNTRY OF APPLICANT FOR NON-EU28/EFTA ....................... 81
FIGURE 7-6: GRANTED PATENTS BY COUNTRY OF APPLICANT FOR EU28/EFTA .................................................. 82
FIGURE 8-1: EUROPE IN THE ELECTRONICS VALUE CHAIN ................................................................................... 92
FIGURE 8-2: SHARE OF PRODUCTION CAPACITY BY COUNTRY OF FAB LOCATION IN 2013 ................................. 93
FIGURE 8-3: GDP IMPACTS OF SEMICONDUCTOR INDUSTRY WORLDWIDE ........................................................ 94
FIGURE 8-4: SEMICONDUCTOR MANUFACTURING LANDSCAPE IN EUROPE IN 2013 .......................................... 95
FIGURE 8-5: SHARE OF PRODUCTION IN MICRO- AND NANO-ELECTRONICS ....................................................... 96
FIGURE 8-6: SHARE OF TURNOVER IN MICRO- AND NANO-ELECTRONICS ........................................................... 96
FIGURE 8-7: SHARE OF KETS-ENABLED PRODUCTION IN MICRO- AND NANO-ELECTRONICS .............................. 97
FIGURE 8-8: GEOGRAPHIC DISTRIBUTION OF DIRECT EMPLOYMENT IN THE SEMICONDUCTOR INDUSTRY ....... 97
FIGURE 8-9: ABSOLUTE KETS-ENABLED EMPLOYMENT IN MICRO- AND NANO-ELECTRONICS............................ 98
FIGURE 8-10: SHARE IN KETS-ENABLED EMPLOYMENT, TOP TEN EU28 COUNTRIES IN MICRO- AND NANO-
ELECTRONICS............................................................................................................................................... 99
FIGURE 9-1: GLOBAL MARKET OUTLOOK FOR NANOTECHNOLOGY IN ICT TO 2019 .......................................... 100
FIGURE 9-2: GLOBAL SALES ESTIMATES FOR NANOTECHNOLOGY AND ICT BY MATERIAL TYPE, 2013 AND 2019
.................................................................................................................................................................. 101
FIGURE 9-3: NANOTECHNOLOGY PRODUCTS IN ICT BY APPLICATION ............................................................... 102
FIGURE 9-4: GLOBAL MARKET FOR SPUTTERED MAGNETIC COATINGS USED ON HARD DISCS TO 2019 .......... 104
FIGURE 9-5: GLOBAL MARKET FOR OXIDE THIN FILM MATERIALS USED IN MAGNETIC TAPES ......................... 105
FIGURE 9-6: GLOBAL MARKET FOR THIN FILM MATERIALS IN OPTICAL RECORDING MEDIA ............................ 106
FIGURE 9-7: GLOBAL MARKET FOR SILVER NANOPARTICLES IN ELECTRONIC PRINTING TO 2019 ..................... 111
FIGURE 9-8: GLOBAL MARKET FOR CHEMICAL-MECHANICAL POLISHING COMPOUNDS TO 2019 .................... 114
FIGURE 9-9: GLOBAL MARKET FOR POLYCARBONATE/CARBON NANOTUBE COMPOUNDS TO 2019 ............... 115
FIGURE 9-10: GLOBAL MARKET FOR OF LOW-K NANOFILM MATERIALS TO 2019 ............................................. 116
FIGURE 9-11: GLOBAL MARKET FOR NANOSCALE ELECTRO-CONDUCTIVE COATINGS TO 2019 ........................ 118
FIGURE 9-12: GLOBAL MARKET FOR POSS NANOCOMPOSITES TO 2019 ........................................................... 119
FIGURE 9-13: GLOBAL SALES FOR NANOPARTICLES USED IN CERAMIC CAPACITORS TO 2019 ......................... 121
FIGURE 9-14: GLOBAL MARKET FOR NANO-MAGNETIC COMPOSITES IN ELECTRONIC AND ELECTRICAL DEVICES
TO 2019 ..................................................................................................................................................... 122
FIGURE 9-15: GLOBAL MARKET FOR TRANSPARENT ELECTRODES TO 2019 ...................................................... 126
FIGURE 10-1: TYPE OF WEBSITE FOR THE TOP 100 NEWS ITEMS FOR NEUROMORPHIC AND NANO-
ELECTRONICS............................................................................................................................................. 141
FIGURE 10-2: TRENDS OVER TIME IN GOOGLE SCHOLAR RESULTS FOR THE “GRAPHENE” AND “GRAPHENE
ELECTRONICS” ........................................................................................................................................... 142
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NanoData – Landscape Compilation - ICT
Tables
TABLE 3-1:NUMBER OF PROJECTS AND SHARES FOR TOTAL PROJECTS AND FOR NANOTECHNOLOGY.............. 27
TABLE 3-2: NUMBER OF PROJECTS AND SHARES FOR NANOTECHNOLOGY AND ICT NANOTECHNOLOGY ......... 28
TABLE 3-3: FP6 ICT NANOTECHNOLOGY ACTIVITIES BY PROGRAMME AND SUB-PROGRAMME ......................... 29
TABLE 3-4: FP7 ICT NANOTECHNOLOGY ACTIVITIES BY PROGRAMME AND SUB-PROGRAMME ......................... 31
TABLE 3-5: PARTICIPATIONS IN FP6 AND FP7 INCLUDING FUNDING AND SHARE OF FUNDING .......................... 32
TABLE 3-6: ORGANISATIONS PARTICIPATING IN FP6 AND FP7, TOP 25 RANKED BY FUNDING RECEIVED ........... 34
TABLE 3-7: COMPANIES PARTICIPATING IN FP6 AND FP7, TOP 25 RANKED BY FUNDING RECEIVED .................. 35
TABLE 3-8: TOP FIFTEEN COUNTRIES FOR FP PARTICIPATION RANKED BY FUNDING RECEIVED ......................... 36
TABLE 3-9: COUNTRY RANKING BY FP FUNDING FOR TOP TEN IN FP, NT AND ICT NANOTECHNOLOGY ............ 36
TABLE 4-1: MEMBER STATE POLICIES AND PROGRAMMES FOR NANOTECHNOLOGY ......................................... 47
TABLE 6-1: ANNUAL NST PUBLICATION OUTPUT FOR ICT WORLDWIDE AND IN THE EU28&EFTA, 2000-2014 .. 70
TABLE 6-2: MOST COMMON JOURNALS BY NUMBERS OF NST ICT PUBLICATIONS (NPUB), 2000-2014 ............. 72
TABLE 6-3: MOST PROLIFIC REGIONS FOR ICT PUBLICATIONS, 2014 ................................................................... 72
TABLE 6-4: NUMBER OF ICT PUBLICATIONS BY COUNTRY (TOP 20), 2014 ........................................................... 73
TABLE 6-5: PUBLICATION NUMBERS FOR NANOTECHNOLOGY AND ICT FOR HIGHER EDUCATION AND
RESEARCH ORGANISATIONS, 2014 ............................................................................................................. 74
TABLE 6-6: NUMBER OF ICT PUBLICATIONS BY EU&EFTA ORGANISATION (TOP TEN), 2014 ............................... 75
TABLE 6-7: NUMBER OF ICT PUBLICATIONS BY COMPANY (TOP 8), 2014............................................................ 75
TABLE 7-1: ABSOLUTE NUMBERS AND PERCENTAGES OF PATENTS ON ICT AND NANOTECHNOLOGY ............... 76
TABLE 7-2: NUMBER OF NANOTECHNOLOGY ICT PATENT FAMILIES BY PCT RECEIVING AUTHORITY ................. 78
TABLE 7-3: ORIGIN OF PATENT APPLICANTS, EU/EFTA AND REST OF WORLD (1993-2011) ................................ 78
TABLE 7-4: PATENT FAMILIES BY COUNTRY OF APPLICANT, NUMBERS AND PERCENTAGES (1993-2011) .......... 79
TABLE 7-5: PATENT FAMILIES BY COUNTRY OF APPLICANT FOR EU28/EFTA (1993-2011) .................................. 81
TABLE 7-6: COUNTRY OF APPLICANT AND NUMBER OF PATENTS GRANTED AT EPO AND USPTO ...................... 82
TABLE 7-7: COMPARISON OF PATENT FILINGS AND PATENTS GRANTED BY COUNTRY OF APPLICANT (1993-
2011) ........................................................................................................................................................... 83
TABLE 7-8: ESTIMATE OF RELATIVE PATENTING SUCCESS BY COUNTRY OF APPLICANT ..................................... 83
TABLE 7-9: COUNTRY OF APPLICANT AND COUNTRY OF INVENTOR TABLE FOR CROSS-COMPARISON .............. 84
TABLE 7-10: NUMBER OF PATENT FAMILIES FOR TOP TEN UNIVERSITIES AND PROS (1993-2011) ..................... 84
TABLE 7-11: NUMBER OF PATENT FAMILIES IN THE TOP 20 EU28/EFTA UNIVERSITIES AND PROS (1993-2011) 85
TABLE 7-12: UNIVERSITIES / RESEARCH ORGANISATIONS GRANTED PATENTS, BY EPO PATENT NUMBERS ....... 86
TABLE 7-13: UNIVERSITIES / RESEARCH ORGANISATIONS GRANTED PATENTS, BY USPTO PATENT NUMBERS .. 86
TABLE 7-14: NUMBER OF PATENT FAMILIES FOR TOP TEN COMPANIES (1993-2011) ......................................... 87
TABLE 7-15: NUMBER OF PATENT FAMILIES FOR TOP TEN NON-US COMPANIES (1993-2011) .......................... 87
TABLE 7-16: NUMBER OF PATENT FAMILIES FOR TOP TEN NON-US COMPANIES (1993-2011) .......................... 88
TABLE 7-17: USPTO AND EPO GRANTED PATENTS BY COMPANY (SORTED BY US PATENTS) .............................. 88
TABLE 8-1: NUMBER OF MANUFACTURING ENTERPRISES INVOLVED IN ICT MANUFACTURING ........................ 89
TABLE 8-2: TURNOVER, PRODUCTION VALUE AND VALUE ADDED OF ICT MANUFACTURING ENTERPRISES ...... 90
TABLE 8-3: EMPLOYMENT IN EU MANUFACTURING ENTERPRISES INVOLVED IN ICT .......................................... 91
TABLE 9-1: GLOBAL MARKET VALUES FOR ELECTRONICS (MULTIPLE SOURCES) ............................................... 101
TABLE 10-1: OVERVIEW OF REGULATIONS FOR NANOTECHNOLOGY USE IN EUROPE ...................................... 132
TABLE 10-2: HAZARD BANDS FOR THE SPECIFIED NANOPARTICLES .................................................................. 135
TABLE 10-3: PRIORITY BANDS IN THE STOFFENMANAGER SYSTEM ................................................................... 138
TABLE 10-4: PRIORITY BANDS FOR THE ICT SECTOR ........................................................................................... 139
TABLE 10-5: FREQUENCY OF ARTICLES ON THE WEB, IN THE NEWS FOR NANOTECHNOLOGY ICT TOPICS ...... 140
TABLE 10-6: FREQUENCY ON GOOGLE SCHOLAR OF NANOTECHNOLOGY ICT TOPICS ...................................... 141
TABLE 10-7: ASSESSMENTS BY THE PUBLIC OF VARIOUS APPLICATIONS OF NANOTECHNOLOGY .................... 143
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ACKNOWLEDGEMENT
The authors of this report wish to acknowledge the valuable guidance and support received
from the numerous experts from research, industry and policy who were consulted during
the project, through interviews, in workshops and other meetings, and via surveys and
questionnaires.
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NanoData – Landscape Compilation - ICT
EXECUTIVE SUMMARY
Background
This report offers a snapshot of the status of the environment for nanotechnology in the context of
information and communications technologies (ICT). Analysis of that environment, trends in the
data, and the effects of European policies and actions on nanotechnology, will be reported in the
NanoData ICT Impact Assessment and are therefore not included in this report.
Role of nanotechnology
In using new methods and new technologies, the main goal of manufacturers of traditional ICT, such
as chips for electronics, is to make smaller, faster and better devices. Reduced size means that more
components and more functionalities can be put into a device. Faster and better devices are built
with components with better computing speed and capacity. Better devices may also have the ability
to process and/or store more data. Associated goals are to minimise costs of materials and
manufacture, as well as to optimise performance, e.g. by controlling the heating of components.
Nanotechnology can contribute to all these goals through coatings, particles and films but also, in
the future, perhaps through radical changes in how ICTs work, though the use of spin (rather than
charge) in technologies known as spintronics, quantum computing and DNA computing.
Policies
National policies to support nanotechnology tend to be generic at Member State level in that they
may support nanotechnology within broad science and technology (S&T) initiatives (e.g. Innovate
UK in the United Kingdom, which funds S&T across the board) or support it as a designated priority
but usually do not single it out for specific measures (e.g. NanoNext in the Netherlands). Examples
of initiatives in which nanotechnology and ICT (or related areas) have been specified together include
the establishment of IMEC1 in Belgium; the founding of the Iberian Nanotechnology Laboratory 2 in
Portugal; and the thematic calls of the ANR3 in France (on miniaturisation, new technologies and
new devices for electronics and nano-photonics).
European supports are concentrated in the EU RTD Framework Programmes (see below under EU
R&D projects) as these have the greatest role in EU funding of nanotechnology R&D (research and
development). Other policies include those for industry and for ICT. There are many examples of
collaborative and co-ordination mechanisms at European level including ERA-NET4s, European
Technology Platforms (ETPs) and Networks of Excellence (NoEs), not least NANOFUNCTION, CHIST-
ERA, ETP4HPC and ECSEL. In ICT policy, in addition to the Framework Programmes, there is the
Digital Agenda for Europe, which aims to exploit the potential of ICT for jobs, growth and society.
Globally outside of the EU, countries that have specified nanotechnology and ICT (or related areas)
as a priority within their policies and programmes at some point in the recent past include the
Russian Federation (with the RUSNANO cluster on optoelectronics and nano-electronics); Japan
(under its Second and Third S&T Basic Plans, 2001-2005 and 2006-2010, although Japan has now
moved to more generic priority areas); and Korea (with national programmes and centres). Other
countries include nanotechnology in policies and programmes but do not single out ICT (e.g. India’s
NanoMission).
In terms of available data, this report tracks research and development activities through projects,
publications and patents to products and markets in the context of the wider socio-economic
environment.
EU R&D projects
For projects at the European level, nanosciences and nanotechnologies (NT) were first provided for
at a significant level in FP6, taking about 10% of the budget (EUR 1,703 million for nanotechnology
out of EUR 16,692 million for FP6) mainly under the headings of NMP (EUR 870 million); Information
Society (EUR 346 million); and Life Sciences (EUR 54 million), as well as Human Resources and
1
Interuniversitair Micro-Electronica Centrum, http://www2.imec.be/be_en/about-imec.html
2
http://inl.int/
3
http://www.agence-nationale-recherche.fr/
4
Also ERA-NET plus
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Publications
Of 1.8 million publications globally related to nanoscience and nanotechnology (NST) between 2000
and 2014, about 130,000 were related to ICT, 7% of the total output.
The strongest publishing countries in 2014 were the China and the US, followed by Korea, Japan,
Germany, India and the United Kingdom. Of the EU28, the strongest in publications in 2014 were
Germany, the United Kingdom, France, Italy and Spain, the top three being the same as for FP
projects.
Thirteen of the top 25 publishing organisations are in China. Of the top ten, six are from China and
two each from Singapore and Korea. There are no European organisations in the top 25.
Looking at EU&EFTA organisations in 2014, these are led by the University of Cambridge (UK), the
University of Paris XI Sud and IMEC, each with over 100 publications. However, there has been no
normalisation of the data to take into account factors influencing publication output such as the
number of researchers/technicians/students or the research budgets. The companies with the most
ICT publications globally in 2014 were IBM, Samsung Electronics and Nippon Telegraph (NTT).
Patenting
The strong presence of countries such as the US, Japan, Korea, Germany and the United Kingdom
is also seen in patenting, with the omission of China and the addition of the Netherlands in the top
six. However, the third placed Korea has less than a quarter of the patent families (422) of the US
(2196) and Japan (1787). Using patenting families11 as the measure, the top EU28 countries for ICT
nanotechnology patenting between 1993 and 2011 were Germany, the Netherlands, the United
5
Centre National de la Recherche Scientifique, the National Centre for Scientific Research www.cnrs.fr
6
Commissariat à l'énergie atomique et aux énergies alternatives, the French Alternative Energies and Atomic
Energy Commission www.cea.fr
7
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. www.fraunhofer.de
8
Max-Planck-Gesellschaft, the Max Planck Society www.mpg.de
9
École Polytechnique Fédérale de Lausanne, the Swiss Federal Institute of Technology in Lausanne
www.epfl.ch
10
Eidgenössische Technische Hochschule Zürich, Swiss Federal Institute of Technology in Zurich www.ethz.ch
11
At the European Patent Office, US Patent and Trademark Office or World Intellectual Property Office
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12
BCC Research
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Some European Member States have put in place additional ways to regulate nanotechnologies (e.g.
using databases and reporting schemes for nanomaterials). Non-EU countries have their own
controls under which nanotechnology and ICT may fall. In general, marketing authorisations must
be applied for on a country by country basis.
The International Organisation for Standardisation (ISO) is responsible for the standardisation of
nanotechnologies but has not directly addressed ICT. The European Committee for Standardisation
committee on nanotechnology (CEN/TC 352) has not developed standards relevant to ICT but covers
ICT and nanotechnology more generally through its working group on health, safety and
environmental aspects. ICT and nanotechnology also fall under the International Electrotechnical
Commission (IEC) and the European Committee for Electrotechnical Standardisation (CENELEC)
committee.
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1 BACKGROUND
The ability to measure and manufacture at the nanoscale is opening up many new avenues within
industry and across society including information and communication technologies (ICT).
This report is a Landscape Compilation of facts and figures related to nanotechnology and ICT. It
offers a snapshot of the status in 2015 of the environment for nanotechnology in the context of ICT.
It documents past and current policies and programmes for nanotechnology (in particular, but not
exclusively, those relating to ICT); the outputs of research (projects, publications and patents) and
how those outputs are used in the application of nanotechnology to ICT (products and markets).
Being a nanotechnology landscape, it does not provide detailed analysis of the data or its trends or
draw policy conclusions. The analysis of the data in this report will be fully presented in the Impact
Assessment report that accompanies it. The Impact Assessment considers the policies and practices
at European level to date (an ex-post evaluation) and looks at gaps in the policies and practices,
concluding with a review of what actions could be taken to enhance nanotechnology and ICT in the
future (an ex-ante analysis).
The outline of this report is as follows:
• Introduction to ICT and the role of nanotechnology;
• Policies and programmes for nanotechnology and ICT;
• Research projects, the EU Framework Programmes;
• Publications in nanotechnology and ICT;
• Patenting in nanotechnology and ICT;
• Industry and nanotechnology for ICT;
• Products and markets for ICT through nanotechnology; and
• The wider environment for nanotechnology and ICT (regulation and standards, environmental
health and safety, communication and surveys on nanotechnology and ICT).
The next section introduces ICT and the role of nanotechnology in addressing it.
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ICT today is mainly semi-conductor and silicon-based, with integrated circuits driving ICT systems
– here called Traditional ICT. Also of relevance in the context of nanotechnology is Frontier ICT,
using new materials and novel systems (including the potential of quantum computing and organic
electronics). The following paragraphs introduce traditional ICT and frontier ICT.
Semiconductors
A semiconductor is a substance that can conduct electricity under some conditions but not
others, making it a good medium for the control of electric current. The ease with which a
semiconductor conducts (its conductance) varies depending on the current or voltage
applied to a control electrode, or on the intensity of irradiation by infrared, visible or
ultraviolet light or X-rays.
The properties of a semiconductor depend on the impurities, or dopants, added to it. An N-
type semiconductor carries current mainly in the form of negatively-charged electrons, in
a manner similar to the conduction of current in a wire. A P-type semiconductor carries
current predominantly as electron deficiencies (holes). A hole has a positive electric charge,
equal and opposite to the charge on an electron. In a semiconductor material, the flow of
holes is opposite in direction to the flow of electrons.
Elemental semiconductors include antimony, arsenic, boron, carbon, germanium, selenium,
silicon, sulphur and tellurium. Silicon is the best-known of these, forming the basis of most
integrated circuits (ICs). Common semiconductor compounds include gallium arsenide,
indium antimonide and the oxides of most metals. See: http://whatis.techtarget.com
13
Transistor: a device that regulates current or voltage flow in a circuit, acting as a switch or gate for
electronic signals.
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Advances in ICT have long been driven by the goal of miniaturisation, making smaller components
in order to make smaller devices and systems and to incorporate a greater number of functionalities
into devices. The rate of miniaturisation was predicted by Moore in 1965 in Moore’s Law, which
states that the number of components on an integrated circuit will increase exponentially over time
i.e. double every year. In 1975, Moore revised his Law to state that the number of components on
an integrated circuit would double every two years.
The Law proved to be accurate in large part, in that industry has delivered smaller and smaller and
more and more powerful devices. The Law has long been used in goal-setting and long-term planning
by the semiconductor and computer industries in the scenario called More Moore. The exponential
trajectory of semiconductor manufacture, and hence computing power, has led to steeply decreasing
costs in ICT making their applications (devices) increasingly accessible to consumers while
constantly offering greater functionality. The ICT giant Intel estimates14 that the transistors it now
produces run 90,000 times more efficiently and are 60,000 times cheaper than the first one it
produced in 1971.
Transistors
Transistors are the basic elements of standard integrated circuits (IC) with many
transistors that are interconnected by circuitry forming a single electronic chip.
The transistor was invented by scientists at Bell Laboratories in 1947, rapidly replacing the
vacuum tube as a regulator for electronic signals. It is a device that regulates current or
voltage flow and acts as a switch (or gate) for electronic signals. Transistors typically
consist of three layers of a semiconductor material, each capable of carrying a current. A
small change in the current or voltage at the inner semiconductor layer (which acts as the
control electrode) produces a large, rapid change in the current passing through the entire
component. The component can thus act as a switch, opening and closing an electronic
gate many times per second. It can also act as a current amplifier. Electrodes can be
attached to each of the three layers of the semiconductors in order to better control the
flow of electrons (or holes) through the transistor.
Field-effect transistors (FETs) use this three electrode system. In some FETs, the
semiconductors layers are coated with metal oxides, forming MOSFETs (metal oxide
semiconductor FETs). Metal oxide semiconductors are also present in CMOS technologies,
complementary metal oxide semiconductor technologies. CMOS technology uses both N-
type and P-type semiconductors in a complementary way for electrical control. Computers
and many other ICT devices use circuitry based on CMOS technology. CMOS components
use almost no power when not needed. However, the direction of the current can be very
rapidly changed in CMOS transistors and they can become hot, limiting the speed at which
circuits such as microprocessors can operate.
See: http://whatis.techtarget.com
The continuation of ‘More Moore’ relies on being able to reduce the size of electronics on an indefinite
basis. While that may be possible for some future years15, companies are also seeking to sustain
and grow their sales by increasing performance through the stacking of components in forms known
as ‘system on a chip’ (SoC) or ‘system in a package’ (SiP). Nanotechnology can contribute not only
in the miniaturisation of ICT (More Moore) but also in this new direction (More than Moore). ‘More
than Moore’ may indeed prove to be the better route for companies, in terms of cost competitiveness,
as the fabrication facilities to make smaller and smaller components (More Moore) require very high
levels of investment in infrastructure, an estimated USD 6 billion in 2015 for a new semiconductor
fabrication plant (a so-called ‘Fab’). New functionality and better performance in semiconductor-
based applications is being targeted through the use of nanostructures such as nanowires and
nanomaterials.
14
Reported in April 2015 in http://www.economist.com/blogs/economist-explains/2015/04/economist-
explains-17
15
Intel expects to be able to maintain the law to 2025 at least, slimming its transistors down to 5nm, about
the thickness of a cell membrane (ibid).
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NanoData – Landscape Compilation - ICT
Moving away from semiconductors, silicon photonics is being seen as a future means to enable the
transmission of huge amounts of data at very high speeds with extremely low power over thin optical
fibres. Combining these with semiconductor electronics, systems in a package may be able to
integrate extremely fast III-V circuits with silicon-based circuits for transmission via optical fibres.
17
NanoData – Landscape Compilation - ICT
16
A quantum bit is analogous to the binary digits (bits) of classical computing and relies on a two-state
quantum-mechanical system (e.g. the polarisation of a photon, the two states being vertical and
horizontal polarisation).
17
http://www-03.ibm.com/press/us/en/pressrelease/46725.wss
18
http://www.dwavesys.com/press-releases/d-wave-systems-announces-multi-year-agreement-provide-its-
technology-google-nasa-and
19
New Journal of Physics 17, 033033, http://m.iopscience.iop.org/article/10.1088/1367-
2630/17/6/063008/pdf
20
http://m.iopscience.iop.org/article/10.1088/0957-4484/26/22/222001/meta#nano512242fn3
21
http://www.graphene.manchester.ac.uk/
22
http://gr-sci.net/papers/10-02.PDF
18
NanoData – Landscape Compilation - ICT
23
http://www.smart-systems-integration.org/public/about/objectives-mission (Strategic Research Agenda,
accessed Nov. 2015)
24
http://esa.un.org/unpd/wpp/
25
http://www.nice.org.uk/guidance/ta151
26
http://phys.org/news/2015-05-e-skin-pocket-sized-diagnostic-machines-patients.html#jCp
27
http://www.sciencedaily.com/releases/2015/05/150512090729.htm
28
http://www.ifm.liu.se/applphys/biosensors-and-bioelectro/research/biosensors/
19
NanoData – Landscape Compilation - ICT
Working at the level of nanotechnology but further away in terms of development are:
• Combining nano-carriers and MRI scanning for brain cancer therapy29;
• Neural implants for severely disabled or injured people30;
• 3-d scanning to help in the study of degenerative bone diseases such as osteoporosis31;
• Ultrasensitive microRNA sensors for the diagnosis and treatment of pancreatic and other
cancers32; and
• Tissue engineering with ICT controlling and optimising the bioreactor33.
Much of the activity in ICT and nanotechnology for health is around biosensors. Healthcare
companies report that the five technologies of greatest importance to their market are micro-electro-
mechanical systems (MEMS), micro-optical electro-mechanical systems (MOEMS) and micro-fluidics;
micro-sensors and micro-actuators; design and simulation technologies; semiconductor and More-
than-Moore technologies; and micro-nano-bio-systems (MNBS). All of these use or, as scales are
reduced in the search for new and better products and processes, they will use, or become,
nanotechnology. Global sales of biosensors were USD 8.5 billion in 2012 and were expected to double
to USD 16.8 billion by 2018, a large market for nanotechnology-related products across health, food,
environment, etc. Remote patient monitoring (including support systems) has been estimated at a
market value of USD 10.6 billion in 201234 while the total global health and personal well-being
sector was estimated in 2011 to be over USD 300 billion35. The nanotechnology-based medical device
market was estimated to be USD 5 billion in 2014, rising to USD 8.5 billion in 2019 (CAGR 11%) 36.
29
http://phys.org/news/2015-11-nanocarriers-brain-cancer-therapy.html
30
http://actu.epfl.ch/news/neuroprosthetics-for-paralysis-an-new-implant-on-t/
31
http://phys.org/news/2015-11-d-nanostructure-bone-visible.html
32
http://phys.org/news/2015-11-nanotech-based-sensor-micrornas-blood-cancer.html
33
A tissue engineering bioreactor can be defined as a device that uses mechanical means to
influence biological processes. See http://epubs.rcsi.ie/cgi/viewcontent.cgi?article=1045&context=anatart
34
http://www.kaloramainformation.com/about/release.asp?id=3159
35
Medical Devices Industry and Market Prospects 2012-2022, Vision Gain 2012, www.visiongain.com
36
MarketsandMarkets, http://www.marketsandmarkets.com/PressReleases/nanotechnology-medical-
device.asp
20
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While these are the goals of using nanotechnology in traditional ICT and electronics, in the future,
nanotechnology may offer radical new solutions in ICT, including quantum and DNA computing.
Some examples of the ways in which nanotechnology is being used or developed to improve ICT
include:
• Silver nanowires, being highly conductive and flexible, are potential replacements for the indium
tin oxide that is currently used to make transparent, conductive layers for tactile displays 37.
• Nanoscale quantum dots, in the form of a thin film in front of an LCD backlight, are being used
in novel television screens38. Quantum dots (QDs) of different sizes each emit a different colour
of light, improving the reproduction rate and brightness compared with conventional liquid-
crystal or LED displays, making for a more saturated appearance of colour. The QD technology
is also expected to be cheaper than organic LED screens.
• Nanoimprint lithography39 is a technique to produce higher resolution patterns for integrated
circuits than traditional photolithography. It has been used to fabricate field-effect transistors
and single-electron memories. It is a simple, low-cost, and high-throughput process for
replicating micro- and nanoscale patterns using mechanical deformation to create a pattern on
a resist-coated substrate. The resist may be cured using heat or ultra-violet light. One mould
may be used repeatedly to routinely make patterns at the scale of tens of nanometres.
• Nanotechnology-based imaging systems are being used to position components with great
precision in three dimensions in the research, testing and manufacture of ICT and in combination
with ICT systems.40
• Research is underway on carbon nanotubes (CNTs) as integrated light sources, modulators and
detectors in silicon-based photonic devices. Single wall carbon nanotubes (SWNTs) are mono-
dimensional materials, with specific electronic and optical properties relevant to electronics and
opto-electronics devices, including light sources.
• Hard disc drives are magnetic memories that do not lose the information stored in them when
the power is removed. They are however, relatively slow to access, much slower than random
access memories (RAM). Many new solid-state technologies are being developed based on the
magnetic spin of their materials. One such is spin-transfer-torque magnetic RAM (STT-MRAM) in
which the information is stored in the spin of nano-magnets and accessed electrically41. This set
of technologies is known as spintronics42.
• Spin–torque nano–oscillators (STNOs) have outstanding advantages of a high degree of
compactness, high–frequency tunability, and good compatibility with the standard
complementary metal–oxide–semiconductor process, which offer prospects for future wireless
communication.
• Plant-based photonic devices may in the future be used as sensor and communication networks.
Photonic structures occur in plants and fruits as well as in butterflies, beetles, jellyfish and
birds43. In plants, these structures affect the internal absorption and channelling of light. It may
be possible to use this channelling effect in sensors and/or for energy harvesting. Plants may
37
https://www.basf.com/us/en/company/news-and-media/news-releases/2015/03/P-US-14-37.html
38
http://www.ibtimes.com/quantum-dots-promise-cheaper-4k-tvs-are-they-really-better-oled-video-1782802
39
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079920/
40
Physics World Focus on Nanotechnology: reaping the benefits of nanomaterials, May 2015
www.physicsworld.com.
41
http://www.nature.com/nnano/journal/v10/n3/full/nnano.2015.50.html#close
42
http://www.nature.com/subjects/spintronics
43
http://rsif.royalsocietypublishing.org/content/10/87/20130394#sec-9
21
NanoData – Landscape Compilation - ICT
also be able to power a small circuit using the sugars they produce, or act as chemical sensors
and communicate information by fluorescent signalling44.
The purpose of nanotechnology in ICT products currently on the market is discussed in the later
section on Products and Markets.
The next section considers the policies and programmes in place for nanotechnology and ICT.
44
Physics World Focus on Nanotechnology: reaping the benefits of nanomaterials, May 2015
www.physicsworld.com.
22
NanoData – Landscape Compilation - ICT
45
Preventing diseases, protecting EU citizens from cross-border health threats, contributing to innovative
health systems, and facilitating better access to healthcare.
46
For environment, biodiversity and climate change.
47
Supporting relocation for education and training purposes.
48
Supporting the creation and expansion of companies, especially by expanding their research and innovation
activities.
49
Improving trans-European infrastructure for transport, energy and telecommunications.
50
FP6 NMP: Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new
production processes and devices: thematic priority 3 under the 'Focusing and integrating community
research' of the 'Integrating and strengthening the European Research Area' specific programme, 2002-
2006.
51
Joint Technology Initiatives (JTIs) are long-term Public-Private Partnerships which are managed within
dedicated structures based on Article 187 of the Treaty on the Functioning of the European Union (TFEU)
(see more information later in this chapter)
52
http://erc.europa.eu/
23
NanoData – Landscape Compilation - ICT
• The Marie Curie Actions53: total funding of up to EUR 4.7 billion FP7 in 2007-2013 (and EUR 6.16
billion Horizon 2020 funding in 2014-2020) for training, mobility and career development of
researchers with 10% of nanotechnology ICT funding; and
• The Capacities Programme54: total budget of EUR 4.1 billion for research infrastructure; research
for the benefit of SMEs; regions of knowledge and support for regional research-driven clusters;
research potential of Convergence Regions; science in society; support to the coherent
development of research policies; and international co-operation, with 2% of nanotechnology
ICT funding.
Framework Programme funding is covered in much greater detail later in this chapter.
ICT, Nano and Health: the Micro- and Nano-Bio Systems cluster in FP6 and FP755
One ICT activity of relevance to nanotechnology and health is the Micro- and Nano-Bio Systems
cluster that looks at how systems can be integrated for applications that have, or interact with,
biological components. Other areas of application include environmental monitoring, and food
and beverage quality and safety.
MNBS projects to date have had targets of achieving substantial improvements via system
integration (e.g. miniaturisation and reduced power consumption, integration of molecular and
cell biology), improving system quality and/or reliability, and reducing the time-to-
market. MNBS has sub-groups on biomedical applications; miniaturised and lab-on-chip
systems for biological (in vitro), chemical and biochemical analysis; and systems for in vivo
interaction with the human body, etc. These aim, inter alia, to accelerate the development of
integrated diagnostic, monitoring and therapeutic devices.
Mechanisms for collaboration on nanotechnology and ICT include, inter alia, the ERA-NETs, Networks
of Excellence (NoEs) and ESFRI, as outlined below. Later in the report, there is coverage of EUREKA’s
Eurostars; the European Technology Platforms; and the Joint Technology Initiatives (and Joint
Undertakings).
The ERA-NET scheme began under FP6 to support collaboration between and co-ordination of
national research programmes. For example, some activities of the ERA-NET ERA-SPOT - Strengthen
Photonics and Optical Technologies for Europe (2005-2009, total funding EUR 880,000, started by
funding agencies from Austria, France, Germany, Slovenia, and Sweden) are relevant to the ICT
sector. ERA-SPOT aimed to consolidate activities in optical technology (OT) through the co-ordination
of national research funding programmes, by developing and implementing joint strategies and
actions.
The ERA-NET scheme continued under FP7 to develop and strengthen the co-ordination of national
and regional research programmes through ERA-NET Plus actions, providing in a limited number of
cases with high European added value, additional EU financial support to facilitate joint calls for
proposals between national and/or regional programmes. For example, ERANET+ projects targeting
ICT have been funded in OLAE+.
OLAE+56 (2011-2016, funding EUR 6 million) is the Organic and Large Area Electronics European
competition for collaborative R&D funding. Its goal is to consolidate funding activities throughout
Europe and achieve the best possible exploitation of the resources and the innovative potential of
European industry and science. OLAE+ uses joint calls focussing on organic and large area
electronics technology, materials and systems. The topic and basic concept for this ERANET+
originated from the Mirror Group of the European Technology Platform Photonics21 that was made
up of governmental representatives from the Member and Associated States involved with the
promotion of photonics.
53
http://ec.europa.eu/research/mariecurieactions/ Marie Curie Actions became Marie Skłodowska-Curie
Actions under Horizon 2020.
54
http://ec.europa.eu/research/fp7/index_en.cfm?pg=capacities
55
http://cordis.europa.eu/fp7/ict/micro-nanosystems/home_en.html
56
www.olaeplus.eu/
24
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Under FP7, there are also the two examples of CHIST-ERA and ICT-AGRI:
• CHIST-ERA57, the European Co-ordinated Research on Long-term Challenges in Information and
Communication Sciences & Technologies, is carried out by national and regional research funding
organisations with the contribution of the EU. The main purpose is to foster co-operation across
countries, with the greater level of attention being on research that involves multiple disciplines.
In the last few years, the topics on which the calls were issued were the Internet of Things, the
terahertz band for next-generation mobile communication systems, and quantum information
and technologies.
• Also partially related to nanotechnology and ICT is ICT-AGRI58, which aims to support “the
effectiveness and efficiency of national research programmes within information and
communication technology (ICT) and robotics for a competitive, sustainable and
environmentally-friendly agriculture”.
Networks of Excellence (NoE) were introduced in the Sixth Framework Programme (FP6) with the
objective of combatting fragmentation in the European Research Area (ERA) by integrating the
critical mass of resources and expertise needed to enhance Europe’s global competitiveness in key
areas relevant to a knowledge-based economy. These bottom-up initiatives are led by consortia
targeting specific research or technological challenges. They include NANOFUNCTION and
ACROPOLIS:
• The NANOFUNCTION ICT Network of Excellence (Beyond CMOS nano-devices for adding
functionalities to CMOS) received an EC research funding contribution of EUR 2.8 million (2010-
2013). The consortium involves partners from industry and academia located in ten Member
States, working on the integration of nanostructures with CMOS (complementary metal–oxide–
semiconductor) chips in order to improve the range of functionality on a nano scale59. The
partners concentrated on “ultra-sensitive nano-sensors capable of detecting signals in
molecules; nano-structures for harvesting energy for the development of autonomous nano-
systems; nano-devices for spot cooling of integrated circuits; and nano-devices for radio-
frequency (RF) communication”60.
• ACROPOLIS61 (Advanced coexistence technologies for radio optimisation in licensed and
unlicensed spectrum) was established in 2010 with mainly academia partners. Its objective is to
“maximise the potential of wireless communications systems” and “to reduce the fragmentation
of research in Europe on coexistence technologies such as spectrum sharing and cognitive radio”.
It has received an EU research funding contribution of EUR 3 million.62
European research is also being co-ordinated through collaboration on the development, establishing
and running of large research infrastructures, so large that they cannot easily be funded by one
agency or country alone. Under the auspices of the European Strategic Forum on Research
Infrastructures (ESFRI)63, Member States are coming together to fund infrastructures related to ICT,
energy, health and other fields. EU grants support the preparatory phases of all selected projects
and assist in implementation and operation of prioritised projects. There was EU funding of EUR 1.85
billion in FP7 and about EUR 2.5 billion in Horizon 2020. Research infrastructures relevant to ICT
include the project Partnership for Advanced Computing in Europe (PRACE) 64 and the European
Magnetic Field Laboratory (EMFL) 65, which form part of the infrastructure needed to enable ICT
applications of nanotechnology.
57
http://www.chistera.eu/
58
http://www.era-platform.eu/era-nets/ict-agri/
59
http://cordis.europa.eu/project/rcn/95145_en.html
60
http://cordis.europa.eu/programme/rcn/853_en.html
61
http://www.ict-acropolis.eu/.
62
http://cordis.europa.eu/project/rcn/95593_en.html
63
http://ec.europa.eu/research/infrastructures/index_en.cfm?pg=home
64
http://www.prace-project.eu/
65
www.emfl.eu
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Other mechanisms to support research and innovation in nanotechnology and ICT are outlined in
the section on Other EU Policies: Industry, later in this chapter. They include:
• EUREKA’s Eurostars;
• European Technology Platforms; and
• Joint Technology Initiatives (and Joint Undertakings).
The next section reports on funding and participation data for the Sixth and Seventh EU Framework
Programmes, FP6 and FP7.
26
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3.2 The EU Framework Programme: funding and participation data for FP6 and
FP7
3.2.1 Overview
Project-related data was extracted from the eCorda database for the EU Sixth Framework
Programme (FP6) and the EU Seventh Framework Programme (FP7)66. The total number of projects
was 35,265, of which 25,238 were FP7 projects and 10,027 were FP6 projects. There were 210,177
participations, of which 133,615 were in FP7 and 76,562 were in FP6.
From the initial set of 35,265 projects, 4,143 were found to be related to nanotechnology in that
they contained, in the title or abstract of the project, the term “nano” 67 or another relevant term68.
Thus, nanotechnology projects form over 10% of the total FP projects. The share of nanotechnology
projects increased slightly between FP6 (10.4%) and FP7 (12.3%).
75% of the 4,143 projects were FP7 projects and 25% were FP6 projects. The relative shares of
nanotechnology projects were similar to those found for FP projects in general (72% in FP7 and 28%
in FP6).
Table 3-1:Number of projects and shares for total projects and for nanotechnology
66
It should be noted that the FP7 projects may not represent the total number of projects that will take
place during FP7 but include only the projects funded up until the date when the extraction of data
from eCorda was made (January 2015).
67
The term “nano” could appear as a part of a word (e.g. nanotechnology, nanoscience, nanomaterial,
nanoscale), as a part of compound word separated with hyphen (e.g. nano-science) or as an independent
word “nano”.
68
Unlike the other sectors considered by the project (HT, EN, PH, MF), for ICT additional projects were
identified by use of keywords such as graphene. These were judged to be too important in ICT to be
omitted. This did, however, result in the total number of nanotechnology projects being different for ICT
(4,143) and the other sectors (3,544).
69
See Annex for details of keywords
27
NanoData – Landscape Compilation - ICT
Table 3-2: Number of projects and shares for nanotechnology and ICT nanotechnology
Numbers of projects
Total FP7 FP6
Total FP projects, all topics 35,265 25,238 10,027
Nanotechnology FP projects 4,143 3,096 1,047
ICT nanotechnology FP projects 1,307 988 319
9,000.0 35.5%
35.3%
8,000.0
35.0%
Share of EC contribution (%)
34.8%
EC contribution (MEUR)
7,000.0
34.5%
6,000.0
Figure 3-1: Funding of ICT nanotechnology for FP6 and FP7 together, for FP7 and for FP6
28
NanoData – Landscape Compilation - ICT
I Focusing and Integrating ERA 4,735 535 174 13,445.0 1,618.5 584.7 80.5% 82.5% 89.3%
Thematic Priorities 3,374 461 163 12,027.5 1,543.4 574.7 72.1% 78.7% 87.7%
2. Information Society 1,089 135 97 3,798.9 525.3 370.9 22.8% 26.8% 56.6%
4. Aeronautics and Space 241 8 4 1,066.1 23.1 13.6 6.4% 1.2% 2.1%
5. Food Quality and Safety 189 0 0 754.2 0.0 0.0 4.5% 0.0% 0.0%
7. Citizens and Governance 143 3 0 236.6 2.4 0.0 1.4% 0.1% 0.0%
Horizontal Research Involving SMEs 490 33 5 463.1 27.5 4.2 2.8% 1.4% 0.6%
Research and Innovation 240 3 0 224.0 3.9 0.0 1.3% 0.2% 0.0%
Human Resources and Mobility 4,546 478 141 1,723.1 243.0 61.3 10.3% 12.4% 9.4%
Science and Society 163 10 1 79.5 6.0 0.2 0.5% 0.3% 0.0%
III Strengthening the ERA 118 3 0 317.3 8.0 0.0 1.9% 0.4% 0.0%
Research & Innovation Policies 19 0 0 13.5 0.0 0.0 0.1% 0.0% 0.0%
TOTAL 10,027 1,047 319 16,692.3 1,961.7 655.2 100.0% 100.0% 100.0%
29
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70
Data extraction January 2015
30
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COOPERATION 7,834 976 388.0 28,336.3 3,565.9 1,383.1 63.1% 62.9% 69.2%
Food, Agri and Bio 516 25 0 1,850.7 97.1 0.0 4.1% 1.7% 0.0%
ICT 2,328 330 256 7,877.0 1,169.3 921.8 17.5% 20.6% 46.1%
Joint Technology Initiatives 736 61 34 1,966.4 204.1 167.0 4.4% 3.6% 8.3%
IDEAS 4,525 654 207 7,673.5 1,173.2 376.2 17.1% 20.7% 18.8%
European Research Council 4,525 654 207 7,673.5 1,173.2 376.2 17.1% 20.7% 18.8%
PEOPLE 10,716 1,305 371 4,777.5 657.7 201.0 10.6% 11.6% 10.0%
Marie-Curie Actions 10,716 1,305 371 4,777.5 657.7 201.0 10.6% 11.6% 10.0%
Research for the benefit of SMEs 1,028 78 10 1,249.1 99.9 15.7 2.8% 1.8% 0.8%
TOTAL 25,238 3,096 988 44,917.3 5,671.8 2,000.1 100.0% 100.0% 100.0%
31
NanoData – Landscape Compilation - ICT
Total FP6 and FP7 NT in FP6 and FP7 ICT in NT in FP6 and FP7
EC Share of EC Share of EC Share of
Particip. Particip. Particip.
Funding Funding Funding Funding Funding Funding
HES 76,777 25,736.0 41.8% 9,145 3,552.5 46.6% 3,136 1,190.9 44.9%
REC 53,384 17,304.4 28.1% 5,564 2,175.2 28.5% 1,775 778.9 29.3%
PCO 25,067 7,021.3 11.4% 2,893 810.2 10.6% 1,196 418.6 15.8%
SME 29,428 6,882.6 11.2% 3,687 878.2 11.5% 820 199.3 7.5%
Other 24,961 4,626.8 7.5% 1,262 210.3 2.8% 351 67.5 2.5%
Total 209,617 61,571.1 100.0% 22,551 7,626.4 100.0% 7,278 2,655.3 100.0%
Higher education institutes (HES) received close to half (44.9%) of the EC contribution to
nanotechnology and ICT, as shown in the table above and the figure below. They are followed by
research organisations (REC, 29.3%), large companies (PCO, 15.8%), small and medium-sized
companies (SME, 7.5%) and other organisations (OTH, 2.5%).
Figure 3-2: Shares of EC contribution by organisation type for nanotechnology and ICT
The proportion of funding going to organisations in the higher education sector (44.9%) is only
slightly lower than that corresponding to their share of nanotechnology funding (46.6%), and higher
71
The EC contribution in eCorda projects and the participant database differ by a small amount. The figures
reported here for participants therefore do not exactly match those for projects in previous sections.
32
NanoData – Landscape Compilation - ICT
than their share for FP funding overall (41.8%). The relative importance of HES rose from 39.6% in
FP6 to 46.6% of all ICT funding in FP7.
For research organisations, their share dropped from FP6 (33.4%) to FP7 (28%). The proportion
going to companies rose from FP6 to FP7 (from 14.3% to 16.2% in the case of PCOs; and from 5.4%
to 8.2% for SMEs).
Overall, the participant types are rather aligned with those of NT and FP. The only significant
differences occur for large companies (where the percentage of EC funding is higher for ICT), and
SMEs, where the opposite is true.
72
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, the French Alternative Energies and Atomic
Energy Commission www.cea.fr
73
Centre National de la Recherche Scientifique, the National Centre for Scientific Research www.cnrs.fr
74
Interuniversitair Micro-Elektronica Centrum Vzw, www.imec.be
75
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. www.fraunhofer.de
33
NanoData – Landscape Compilation - ICT
Table 3-6: Organisations participating in FP6 and FP7, top 25 ranked by funding received
76
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, the French Alternative Energies and Atomic
Energy Commission www.cea.fr
77
Centre National de la Recherche Scientifique, the National Centre for Scientific Research www.cnrs.fr
78
Interuniversitair Micro-Elektronica Centrum Vzw, www.imec.be
79
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. www.fraunhofer.de
80
École Polytechnique Fédérale de Lausanne, the Swiss Federal Institute of Technology in Lausanne
www.epfl.ch
81
http://www.chalmers.se/en/About-Chalmers/Pages/default.aspx
82
Consiglio Nazionale Delle Ricerche, the Italian National Research Council www.cnr.it
83
Max-Planck-Gesellschaft, the Max Planck Society www.mpg.de
84
Eidgenössische Technische Hochschule Zürich, Swiss Federal Institute of Technology in Zurich www.ethz.ch
85
Teknologian Tutkimuskeskus, Technical Research Centre of Finland www.vtt.fi
86
https://www.kth.se/en
87
http://www.weizmann.ac.il/pages/
88
http://www.fz-juelich.de/portal/DE/Home/home_node.html
89
Consejo Superior de Investigaciones Cientificas, the Spanish National Research Council www.csic.es
34
NanoData – Landscape Compilation - ICT
Table 3-7: Companies participating in FP6 and FP7, top 25 ranked by funding received
35
NanoData – Landscape Compilation - ICT
Table 3-9: Country ranking by FP funding for top ten in FP, NT and ICT nanotechnology
(Listed in order of received ICT nanotechnology funding, highest at the top of the table)
The top three countries accounted for almost half of the total EC funding for ICT nanotechnology
projects. The same three countries, in almost the same order, head the ranking for nanotechnology
projects and for FP projects overall, as seen in the table below. The list is topped by Germany with
a share of 19%, followed by France (16.4%) and the UK (11.7%). Other countries, like Italy, the
Netherlands and Switzerland, follow at a distance.
36
NanoData – Landscape Compilation - ICT
The figure below shows the ranking of countries participating in ICT nanotechnology projects. In
most cases, the share of funding for ICT nanotechnology projects is lower than the shares for both
nanotechnology projects and FP projects as a whole. There are some exceptions to this rule, with
France, in particular, and then Belgium, Germany, Switzerland and Austria having higher
percentages of funding for ICT nanotechnology. It is worth mentioning the case of France with a
share of funding of ICT nanotechnology projects that is 4.1% higher than its share of funding of
nanotechnology projects. It can be concluded that these countries show a higher specialisation in
the field of ICT nanotechnology.
Figure 3-3: Percentage shares of FP funding by country in FP, NT and ICT nanotechnology
In the figure below (the EC funding for ICT nanotechnology projects in FP6 and FP7 (bars) and the
country shares (points or diamonds), five countries have increased their share of funding for ICT
nanotechnology projects from FP6 to FP7 (The Netherlands, Switzerland, Spain, Sweden and
Austria). The Netherlands and Switzerland are the most significant cases, as they increased their
shares of funding from 4.6% to 7.3% and from to 4.7% to 6.6%, respectively. Belgium, on the other
hand, reduced its share of funding from 7.2% in FP6 to 4.6% in FP7.
37
NanoData – Landscape Compilation - ICT
Figure 3-4: EC funding for ICT NT activities in FP6 and FP7 in MEUR and country shares
Of the 106 projects, ten were classified by review as being related to ICT and nanotechnology. Those
ten projects reported outputs of:
• 171 publications, an average of 17 publications per project, the same as for nanotechnology
overall; and
• 6 patent applications, an average of 0.6 per project, slightly less than for nanotechnology overall.
Thus, of the projects under review, ICT nanotechnology projects under FP7 produce the average
number of publications and less than the average patents for nanotechnology FP7 overall, as
captured in the SESAM reports to date.
The next section considers EU policies and programmes that complement the supports for
nanotechnology described previously in this section for the EU Framework Programmes.
38
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90
http://ec.europa.eu/cip/
91
http://ec.europa.eu/cip/ict-psp/index_en.htm
92
http://ec.europa.eu/digital-agenda/en/news/communication-european-strategy-micro-and-nanoelectronic-
components-and-systems
93
https://www.eurostars-eureka.eu/
39
NanoData – Landscape Compilation - ICT
Another type of mechanism is the European Technology Platform (ETP)94. ETPs are bottom-up,
industry-led stakeholder fora, the aim of which is to increase interaction between research actors
and to facilitate the development of medium to long-term research and technological goals and
associated roadmaps. They do not fund research projects but are a co-ordination mechanism. ETPs
contribute to design, and update and provide recommendations on the Strategic Research Agenda
on the specific sector with which they are dealing. ETPs now exist across the themes of ICT, energy,
environment, production and processes, transport and the bio-based economy.
Under the ICT themes, the ETPs ARTEMIS, ENIAC, EPoSS, ETP4HPC, euRobotics, NEM, NESSI,
Networld 2020 and Photonics21 are listed. The most relevant for this report include NEM, ETP4HPC
and EPoSS (as well as former ETPs ENIAC and ARTEMIS described below).
• NEM (initially Network and Electronic Media Initiative, now New European Media) 95 was launched
under FP7 to help “the convergence between consumer electronics, broadcasting and telecoms”.
It includes the major stakeholders that together developed a Strategic Research and Innovation
Agenda (SRIA). NEM focuses on digital content; distributed media applications; future media
delivery networks and network services; and new user devices and terminals.
• ETP4HPC (the European Technology Platform for High Performance Computing (HPC)) 96, a
contractual Public Private Partnership under H202097, focuses on: new technologies (HPC stack
elements); system characteristics (extreme scale requirements); and new HPC deployments and
HPC usage expansion.
• EPoSS (the European Technology Platform on Smart Systems Integration)98 provides a common
approach on Innovative Smart Systems Integration and integrated Micro- and Nano-systems
from research to production; defines common future priorities and road maps; mobilises
resources. EPoSS represents the Smart Systems community in the Joint Technology Initiative for
Electronic Components and Systems for European Leadership (JTI ECSEL). The platform aims to
provide a common European approach on innovative and smart systems integration from
research to production, with an agreed roadmap for action and a strategic R&D agenda and to
provide the resources to deliver the roadmap from public and private sources. EPoSS has
members in over 20 Member States including large companies, SMEs, universities and other
public organisations undertaking research and development.
• Net!works (now called Networld 2020)99, the European Technology Platform for communications
networks and services, supports the development of mobile and wireless, fixed and satellite
communications.
• Photonics21 (a contractual Private Partnership under H2020) focuses on seven priority areas
(e.g. working groups): information and communication; industrial manufacturing and quality;
life sciences and health; emerging lighting, electronics and displays; security, metrology and
sensors; design and manufacturing of components and systems; photonics research, education
and training.
Joint Technology Initiatives (JTIs) are long-term Public-Private Partnerships managed within
dedicated structures based on Article 187 of the Treaty on the Functioning of the European Union
(TFEU). JTIs support large-scale multinational research activities in areas of major interest to
European industrial competitiveness as well as issues of high societal relevance. They are established
in cases where the scale and scope of the initiative make the loose co-ordination through ETPs and
support by the regular instruments of the Framework Programme for Research and Development
insufficient100. Under FP7, six areas were identified for the development of a JTI: Nano-electronics
(ENIAC)101; Embedded Computing Systems (ARTEMIS); Innovative Medicines; Fuel Cells and
Hydrogen; Aeronautics; and GMES (global monitoring for environment and security).
94
http://ec.europa.eu/research/innovation-union/index_en.cfm?pg=etp
95
http://nem-initiative.org/what-is-nem/
96
http://www.etp4hpc.eu
97
In 2013, under Horizon 2020, the European Commission launched the contractual Public Private Partnerships
(cPPPs) to leverage more than EUR 6 billion of investments through H2020 calls.
98
http://www.smart-systems-integration.org/public
99
http://networld2020.eu/vision-mission/
100
http://era.gv.at/directory/142
101
Since 2014, ENIAC and ARTEMIS has been replaced by ECSEL (https://ec.europa.eu/digital-
agenda/en/time-ecsel )
40
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• ENIAC102, the JTI in nano-electronics. The ENIAC Joint Undertaking was established in February
2008 to co-ordinate European nano-electronics research activities through competitive calls for
proposals. It describes itself as a public-private partnership in nano-electronics strengthening
European competitiveness and sustainability, bringing together the ENIAC Member States, the
European Commission and AENEAS, the association of R&D actors in the field.
• ARTEMIS (Advanced Research & Technology for EMbedded Intelligence and Systems)103 involves
disciplines such as mechanics, electronics, control and software engineering and aims to make
Europe the leader in embedded and cyber-physical systems. ARTEMIS merged into another JTI,
ECSEL, in 2014. The ARTEMIS Industry Association has remained, representing actors in
embedded and cyber-physical systems within Europe. The association represents industry and
the public sector (large companies, SMEs, universities and research institutes) in the ECSEL JU.
• ECSEL is the Joint Technology Initiative for Electronic Components and Systems for European
Leadership104 and is the public-private partnership in electronic components and systems, under
H2020 (covering the topics addressed in FP7 within the ARTEMIS and the ENIAC JTIs and in the
ETP EPoSS). Its consortia are collaborating on projects to develop smart systems; systems and
components for smart energy; smart cities; smart governance; and smart living, including
photonics. The current members of ECSEL are the European Union (through the Commission);
Member States and Associated Countries to Horizon 2020; and three associations (EPoSS 105,
AENEAS and the ARTEMIS Industry Association) representing the actors from the areas of micro-
and nano-electronics, smart integrated systems and embedded/cyber-physical systems.
102
http://www.eniac.eu/web/index.php
103
https://artemis-ia.eu/about_artemis.html
104
http://www.ecsel-ju.eu/web/index.php
105
http://www.smart-systems-integration.org/public
106
https://ec.europa.eu/digital-agenda/en/digital-europe
107
https://ec.europa.eu/digital-agenda/en/future-emerging-technologies-fet
108
https://ec.europa.eu/digital-agenda/future-internet
109
http://www.ict-fire.eu/home.html
110
https://ec.europa.eu/digital-agenda/en/innovation-ict-manufacturing-smes
111
http://i4ms.eu/projects/projects.php
112
Public Private Partnership Factories of the Future (PPP FoF), established in 2008 and continued also under
H2020, targets in particular SMEs and supports them in tackling global competitiveness by improving the
technological base of manufacturing across a broad range of sectors.
113
Former Yugoslav Republic of Macedonia
114
A company with a market capitalisation between USD 2 and USD 10 billion, calculated by multiplying the
number of shares by its stock price.
41
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advances in ICT. Some FP7 projects in the field of HPC cloud-based simulation services and intelligent
sensor-based equipment are associated with this initiative (e.g. INTEFIX, FORTISSIMO, CloudFlow
and CloudSME).
The next section considers Member State policies and programmes for nanotechnology and ICT.
115
http://s3platform.jrc.ec.europa.eu/eye-ris3. As of December 2015, 260 regions and countries that prioritise
KETs; out of these there are 7 regions that have set a priority in nanotechnology.
42
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116
https://www.ffg.at/nano-das-programm
117
http://www2.imec.be/be_en/about-imec/imec-strategy/mission-and-vision.html
118
http://en.innovationsfonden.dk/strategic-research/
119
http://www.tekes.fi/globalassets/julkaisut/finnano_loppuraportti.pdf
120
http://www.tekes.fi/en/programmes-and-services/grow-and-go-global/china/
121
http://www.agence-nationale-recherche.fr/en/projects-and-results/calls-for-proposals-2013/aap-
en/nanotechnologies-and-nanosystems-p2n-2013/
43
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EUR 35 billion economic stimulus package Investissements d’Avenir (Investments for the Future)
was launched at the end of 2009.
Germany: Germany was the first country in Europe to recognise a need for a specific funding
measure for nano-electronics and -photonics, introducing the lead innovation programme “Nanofab”
and “NanoLux” as early as 2001. Even earlier - in 1999 - the German Federal Ministry of Education
and Research (BMBF) launched the Framework Concept for the Production of Tomorrow. The Nanofab
programme ran until 2014 with an overall budget of EUR 403 Million. The main rationale was to
foster the manufacturing industries of Germany in an ever more dynamic and competitive
environment with enhanced mobility of goods, capital and information. The Framework Concept
comprised four thematic fields of action amongst which was the area of production processes and
production equipment (including primary shaping and recasting, chipping, surfaces and layers, heat
treatment, assembling, and measurement engineering). Furthermore, the programme Optical
Technologies (2002-2012, total funding of EUR 275.5 million administered by VDI
Technologiezentrum) supported co-operative R&D projects in the realm of nano-electronics,
information and communication (as well as healthcare systems and biotechnology, environment,
traffic and mobility). Its successor, the Photonics Research programme was launched in 2012 with
a funding of EUR 100 million per annum. It is sub-divided into three fields of action: optical systems,
especially next generation optical systems; innovative applications of light for humans, production
and the environment; and promotion of start-ups and creation of favourable general conditions.
In addition, in Germany at regional level, the Research Strategy of Thuringia (2008) covered
research areas such as photonics; optical technologies, micro- and nano-technologies, micro-
electronics; and information and communication technologies. The main fields of activity of regional
research policy are (i) to support competitiveness; (ii) to strengthen networks; (iii) to support young
researchers; and (iv) to invest in infrastructure.
Italy: The Italian National Research Programme 2004-2006 stressed the importance of
nanotechnology and, among its focus areas, mentioned nano-fabrication and electronics. In
September 2014, MISE (the Ministry for Economic Development) within its FCS (Fondo per la crescita
sostenibile, fund for sustainable growth) allocated EUR 300 million low interest loans (of which 60%
earmarked for SMEs), covering areas including nanotechnology, ICTs, advanced manufacturing, etc.
(only technologies associated with H2020)122.
Lithuania: Since 2012, the Agency for Science, Innovation and Technology (MITA) has actively
promoted innovative start-ups. The High Technology Development Programme (2012) aims to
encourage scientists, researchers and students to establish start-ups or spin-off companies. Thirteen
new companies have obtained public funding (a maximum of EUR 20,000) across high-tech areas
including information technology; nanotechnology; mechatronics; laser technology; and
biotechnology123.
The Netherlands: NanoNed (2004 – 2010, total funding of EUR 235 Million administered by the
Dutch Ministry for Economic Affairs), the Nanotechnology R&D initiative in the Netherlands, has
clustered the Dutch expertise on nanotechnology and enabling technology into a national network.
The NanoNed programme was organised into eleven independent programmes, or flagships,
amongst which were Bottom-up Nano-Electronics and Nano-Fabrication. In 2011, NanoNed was
followed by NanoNextNL124, a consortium of more than a hundred companies, nine knowledge
intensive institutes, six academic medical centres and thirteen universities. Stakeholders collaborate
on fundamental as well as applied research through research projects. NanoNextNL is expected to
grow into an open-innovation ecosystem, with new partners joining the consortium. Industry has
committed to continue its support for NanoNextNL after 2015.
In addition, innovation in the Netherlands is organised under the Top Sector Policy125 announced in
2010. Businesses, researchers and government work closely together in Top consortiums for
Knowledge and Innovation (TKIs). The only policy objective that has been set specifically for the top
sector policy is that public and private parties should participate in the TKIs for an amount of at least
€500 million by 2015, 40% of which should be financed by trade and industry. The formal objective
122
https://rio.jrc.ec.europa.eu/en/country-analysis/Italy/country-report
123
https://rio.jrc.ec.europa.eu/en/country-analysis/Lithuania/country-report
124
http://www.nanonextnl.nl/
125
http://www.hollandhightech.nl/nationaal/innovatie/roadmaps/smart-industry
44
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set for the top sector policy is that it should contribute to “a stronger innovative capacity in the
Dutch economy.” i.e. that the Netherlands will be ranked among the top five knowledge economies
worldwide by 2020 and will spend 2.5% of GDP on R&D by 2020.
One of the nine top sectors is High Tech Systems and Materials with its roadmap on nanotechnology
(implemented by TKI NanoNext) as an enabling and cross-cutting technology. The aim of the
roadmap is to enable research that will lead to new applications to address the challenges that
society currently faces. Advances in mechatronics and manufacturing are being coupled with those
in nanotechnology for areas including energy efficiency in buildings (energy-efficient building
cooling, heating and lighting control using low cost micro- and nanotechnology-based autonomous
sensors and control systems with local intelligence).
Portugal: The International Iberian Nanotechnology Laboratory126 (INL) was established as the
result of a joint decision of the Governments of Portugal and Spain, in November, 2005. With a total
investment of EUR 46.5 million (of which EUR 30 million came from the European Regional
Development Fund, “Spain – Portugal” Operational Programme, 2007-2013). INL is an international
research organisation in the field of nanoscience and nanotechnology. Established as an
Intergovernmental Organisation (IGRO), the INL is developing itself into a state-of the art research
environment (including nanofabrication facilities) for materials science at nanoscale, nano-
electronics, nano-biotechnology and nanomedicine. In addition to being a facility for researchers in
Portugal and Spain, it hosts those from non-EU countries such as Brazil. Among the key research
activities at INL is nano-electronics (including spintronics, MEMS and nano-devices).
Slovakia: The Ministry of Education, Science, Research and Sports (MESRS) 127 published the Action
Plan for the Innovation Strategy for Smart Specialisation, 2014-2020128. The Action Plan focused on
measures to encourage R&D expenditure of companies and applied research. The Action Plan
identified also seven priority areas that include material research and nanotechnologies (about EUR
42 million) and information and communication technologies (about EUR 10 million). 129
Spain: The Sixth National Scientific Research, Development and Technological Innovation Plan
(2008-2011) included the Strategic Action for Nanoscience and Nanotechnology, New Materials and
New Industrial Processes (SANSNT), which addressed seven priorities, amongst which were nano-
electronics and molecular electronics, optoelectronics and photonics, and semiconductor nano-
structures as well as magnetic information storage and magneto-electronics. Under the Spanish
State Plan for Scientific and Technical Research and Innovation 2013-2016, endorsed in February
2013, a number of funding support instruments are available for the development and dissemination
of Key Enabling Technologies, including nanotechnology.
The United Kingdom (UK): In 2002, the UK Government, after issuing the Taylor Report which
recognised the increase of investment in nanotechnology worldwide, allocated GBP 90 million (EUR
131.4 million)130 of funding for the Micro- and Nano-Technology Manufacturing Initiative. This
funding was committed between 2003 and 2007. Approximately one third of this investment went
to Collaborative R&D MNT Projects, and two thirds to capital infrastructure. Generally built on
existing university or business expertise, the twenty-four facilities are targeted at addressing a broad
range of key application areas where micro/nano scale activity is considered key to future UK
industry capability and where the UK has some strength131.
More generally, the main player in UK policy measures related to nanotechnology as a key enabling
technology (KET) is the Department for Business, Innovation and Skills (BIS) and its agency, the
Technology Strategy Board, now called Innovate UK 132. It supports SMEs with high growth potential,
manages the Small Business Research Initiative133 and identified future potential growth sectors and
126
http://inl.int/
127
https://www.minedu.sk/about-the-ministry/
128
http://s3platform.jrc.ec.europa.eu/regions/SK
129
http://s3platform.jrc.ec.europa.eu/documents/10157/511834/PPT_Slovakia_Dublin%20FINAL%2026%206
%202014.pdf.
130
Average yearly conversion rate, 2003-2007 (source:
https://www.ecb.europa.eu/stats/exchange/eurofxref/html/eurofxref-graph-gbp.en.html )
131
However, following to an evaluation in 2010, the initiative was judged quite unsuccessful (source:
http://www.cientifica.com/why-has-the-uk-given-up-on-nanotechnology/ )
132
https://www.gov.uk/government/organisations/innovate-uk
133
https://www.gov.uk/government/collections/sbri-the-small-business-research-initiative
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commercialisation opportunities. Much of the activity around environment, health and safety in the
UK is under the remit of DEFRA.
The UK Enabling Technologies Strategy 2012-2015134 also addresses four enabling technologies -
advanced materials; biosciences; electronics, sensors and photonics; and information and
communication technology (ICT) to support business in developing high-value products and services
in areas such as energy, food, healthcare, transport and the built environment. Nanotechnology is
identified as having a significant underpinning role across most of these technology areas,
particularly in the healthcare and life sciences sectors.
134
https://www.gov.uk/government/publications/enabling-technologies-strategy-2012-to-2015
46
Table 4-1: Member State policies and programmes for nanotechnology
Country Name of Initiative Dates Relevance Description Target Implementing Budget
Groups Body
(EUR millions)
AT Austrian NANO 2004- Directly Multiannual, funding collaborative R&D, co-ordinating IND SME HEI FFG 70 over 8 years
Initiative135 2011 Targeting NT NANO-related policy measures at national and PRO
regional levels. Since 2012, NT is supported via FFG’s
(NANO) thematic research funding e.g. Production of the
Future
AT ------ From Thematic, not Since 2012, NT R&D is being supported via FFG’s All FFG 450 for all disciplines
2012 NT Specific thematic research funding e.g. Production of the (over the preceding 4
Future years when funding was
managed by BMVIT)
BE IMEC From Thematic, not Since 1984 the Government of Flanders is supporting All Government of Initial investment: 62
1984 NT Specific IMEC research institute Flanders
For every period the
contribution increased
until reaching around
48 in 2011.
DK Strategic Research in From Directly Programme to strengthen research at the bio-nano- IND SME HEI Innovation c. 10 per annum
Growth Technologies136 2005 Targeting NT ICT interface for socio-economic benefit PRO Fund Denmark
FI FinNano137 2005- Directly Multiannual funding for nano S&T to study, exploit IND SME HEI Tekes 70 over 5 years
2009 Targeting NT and commercialise nano. PRO
FR Nanomaterials From Directly Mandatory reporting scheme for nanomaterials of All ANSES n/a
Mandatory Reporting 2013 Targeting NT 100g and above
Scheme138
DE Nanotechnology 2004- Directly Five leading-edge innovation programmes including All BMBF 24 over 3 years
135
https://www.ffg.at/nano-aktuell ; https://www.ffg.at/11-ausschreibung-produktion-der-zukunft
136
http://innovationsfonden.dk/en/about-ifd
137
www.tekes.fi
138
https://www.anses.fr/fr/lexique/nanotechnologies
139
http://www.agence-nationale-recherche.fr/
NanoData – Landscape Compilation - ICT
DE Nano Initiative – Action 2006- Directly Cross-departmental initiative led by BMBF: to speed All BMBF 640 over 5 years
Plan 2010 Targeting NT up the use of the results of nanotechnological
research for innovations; introduce nanotechnology
to more sectors and companies; eliminate obstacles
to innovation by means of early consultation in all
policy areas; and (4) enable an intensive dialogue
with the public.
DE Innovation Alliances 2007- Directly For strategic long-term co-operation between All BMBF 500 over 6 years
2012 Targeting NT multiple industry and public research partners. Funds
R&D, other innovation-related activities. Public and
private funds are combined in a 1:5 ratio.
IT Fondo per la Crescita 2002- Targeting NT In September 2014 MISE issued the call for industrial Mainly SMEs MISE 300
Sostenibile (FCS) 2004 R&D projects of the FCS, covering the fields of ICTs,
nanotechnology, advanced manufacturing, advanced
(Fund for sustainable materials, biotechnology, technologies associated
growth) with the EU Horizon 2020 programme.
LT High Technology 2012- The High Technology Development Programme in SMEs MITA 13 companies obtained
Development Ongoing 2012 aims to encourage scientists, researchers and public funding for a
Programme students to establish start-up or spin-off companies. maximum of around
13 new companies obtained public funding. The high- EUR 20,000 each
tech areas concerned are: information technology,
nanotechnology, mechatronics lasers technology and
biotechnology
NL NanoNed 2004- Directly NanoNed was organised into eleven independent IND SME HEI Dutch Ministry 235 over 8 years
2011 Targeting NT flagships based on regional R&D strength and PRO and for the
industrial relevance, including NanoFabrication and Individuals Economy
NanoElectronics
NL NanoNextNL 2011- Directly Consortium-based system (over one hundred IND SME HEI Dutch Ministry 125 over 5 years
2015 Targeting NT companies, nine knowledge intensive institutes, six PRO and for the
academic medical centres and thirteen universities). Individuals Economy
Stakeholders collaborate on fundamental and applied
research projects. It includes NanoFabrication.
NL Top sectors 2010 to Directly The Top Sector Policy involves government support in IND SME HEI Dutch Ministry Objective for public and
date Targeting NT nine key economic areas (the top sectors) through a PRO for the private sector to
combination of generic (i.e. financial) instruments Economy participate in the Top
and a focused emphasis on achieving optimum Consortia for
cooperation in the „golden triangle‟ formed by Knowledge and
companies, research institutions and government. Innovation (TKIs) for an
The policy works through Top Consortia for amount of at least EUR
48
NanoData – Landscape Compilation - ICT
ES Strategic Action of 2008- Directly To enhance the competitiveness of industry by IND SME HEI Ministry 33 over 4 years
Nano Science, Nano 2011 Targeting NT generating new knowledge and applications based on PRO
technologies, new the convergence of new technologies, where
materials and new nanotechnology plays a central role.
industrial processes
PT International Iberian 2005 to Directly International research organisation in the field of IND SME HEI Governments 46.5 (of which 30 from
Nanotechnology date Targeting NT nanoscience and nanotechnology, the result of a joint of Portugal and ERDF Spain – Portugal”
Laboratory decision of the Governments of Portugal and Spain. Spain Operational
Becoming a state-of the art research environment Programme) over 7
(including nanofabrication facilities) for nano- years
biotechnology, nano-electronics, nanomedicine and
materials science at nanoscale. INL hosts researchers
from the EU and non-EU countries including Brazil.
SK Action Plan for the 2014- Targeting NT, The Action Plan focused on measures to encourage Industry MESRS Around 42 for
Innovation Strategy for 2020 but not only R&D expenditure of companies and applied research. nanotechnology
Smart Specialisation The Action Plan identified also seven priority areas
(RIS3) 2014-2020 that include material research and nanotechnologies Around 10 for ICT
and information and communication technologies.
UK Micro and 2003- Directly Support for collaborative R&D and capital Industry DTI 329 over 4 years, over
Nanotechnology 2007 Targeting NT infrastructure, co-financed by industry 100 from public funds
Manufacturing
Initiative140
UK UK Nanotechnologies 2009- Directly Targets the ways by which nanotechnologies can IND SME HEI TSB, EPSRC,
Strategy 2012 Targeting NT address major challenges facing society such as PRO BBSRC and
environmental change, ageing and growing MRC
populations, and global means of communication and
information sharing.
UK Key Enabling 2012- NT as Addresses four enabling technologies - advanced Business Innovate UK GBP 20m a year in
Technologies Strategy 2015 Underpinning materials; biosciences; electronics, sensors and mainly higher-risk, early-stage
Technology photonics; and information and communication innovation across
technology (ICT) to support business in developing advanced materials;
high-value products and services in areas such as biosciences; electronics,
energy, food, healthcare, transport and the built sensors and photonics;
environment. Nanotechnology is identified as having
140
http://www.innovateuk.org/
49
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50
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141
The UN method of classifying countries by macro geographical (continental) regions and geographical sub-
regions was followed (http://unstats.un.org/unsd/methods/m49/m49regin.htm )
142
http://www.forskningsradet.no/prognett-
nano2021/Artikkel/About_the_programme/1253970633592?lang=en
143
http://www.forskningsradet.no/prognett-nanomat/Programme_description/1226993562834
144
http://www.forskningsradet.no/servlet/Satellite?c=Page&pagename=nano2021%2FHovedsidemal&cid=1253
969916237&langvariant=en
145
http://www.forskningsradet.no
146
At the current exchange rate, October 2015
147
Nanotechnology and Advanced Materials – NANO2021: Work Programme
148
Average yearly conversion rate, 2008-2009 (source: www.wolframalpha.com )
149
Average yearly conversion rate, 2010 (source: www.wolframalpha.com )
51
NanoData – Landscape Compilation - ICT
RUSNANO has a very wide range of activities spanning from research to foresight to infrastructure,
education, standards and certification. Its research projects fall under six clusters, some of them
relevant to ICT, such as the optoelectronics and nano-electronics cluster. As of October 2010, fifteen
out of 83 industrial investment projects had been on nano-photonics, as well as seven on nano-
electronics150.
5.1.1.3 Switzerland
Basic (fundamental) research is funded at national level through the Swiss National Science
Foundation (SNF) and the Commission for Technology and Innovation (CTI) and takes place mainly
in the Swiss Federal Institute of Technology (ETH) and the universities, as well as some 30 research
organisations. Applied research and the transfer of research to market innovation takes place in
industry and “Fachhochschulen” (Universities of Applied Research). Two-thirds of R&D investment
(which in Switzerland is almost at the EU target of 3% of GDP) comes from private industry.
CTI funds the Swiss MNT network (micro and nanotechnology) as one of the core innovative themes
of national and international importance151. The Swiss MNT Network is an R&D consortium of the
major public R&D institutions in micro and nanotechnology whose goal is to simplify access to
industries looking for competences and expertise for their projects152. Members include ETH Zürich,
Hightech Zentrum Aargau, Centre of Micronanotechnology (EPFL), Adolphe Merkle Institute and
companies such as IBM, BASF and Novartis. There are also some regional networks that include
nanotechnology as priority: i-net innovation networks Switzerland – i-net Nano153, and Nano-Cluster
Bodensee154. Most activities are strongly focused on R&D to support industry.
150
Anatoly Chubais, RUSNANO Chief Executive Officer, “RUSNANO: fostering Innovations in Russia through
Nanotechnology”, USRBC 18th Annual Meeting, October 2010, San Francisco, California, USA,
https://www.usrbc.org/pics/File/AM/2010/Presentations/Chubais_GB_830.ppt.pptx
151
https://www.kti.admin.ch/kti/en/home/unsere-foerderangebote/Unternehmen/internationale-netzwerke-
und-forschungskooperationen-neu/spezialthema-japan-schweiz1/foerderlandschaft-schweiz.html
152
http://www.swissmntnetwork.ch/content/
153
http://www.i-net.ch/nano/
154
http://www.ncb.ch/wordpress_neu/
155
Current conversion rates, October 2015
52
NanoData – Landscape Compilation - ICT
merger with the Consortium Innovation Polymères, NanoQuébec has formed part of Prima Québec,
Quebec’s advanced materials research and innovation hub.
Quebec’s Nano Action Plan 2013-2018156 specifically targets four priority sectors: microsystems,
health, industrial materials and forestry. It covers infrastructure, financing of innovation, knowledge
transfer and technology transfer, and national and international outreach horizontally across the four
priority areas.
Via a central point (QNI or Quebec Nanotechnology Infrastructure), it co-ordinates and provides
infrastructure for 300 experts using a fund of CND 300 million (EUR 200 million157). QNI has
particular strengths in micro-nanofabrication, characterisation, synthesis and modelling. Other
infrastructure can be accessed but is not funded via QNI.
The Action Plan has also led to the financing of technological feasibility projects (maximum six
months); collaborative industry/university research projects (one to two years); and international
research projects with strategic NanoQuébec partners. Knowledge and technology transfer are
supported through training, industry internships, and dissemination and awareness activities; by
establishing networks and by organising interactive visits by experts. Outreach actions aim to attract
new projects and finance to Quebec and to increase the engagement in international projects by
people from Quebec.
NanoQuébec collaborates with Prompt, a non-profit corporation whose mission is to encourage
university and industry collaboration in R&D with a particular focus on ICT industry as ICT-related
innovation is considered important for the economy of Quebec (which has 5,000 related companies
with about 140,000 employees).158
Ontario
An ICT-related initiative, but with its main focus on photonics, took place also in Ontario. The
Canadian Photonics Fabrication Centre (CPFC) 159 opened in 2005 as a partnership between the
National Research Council and Carleton University. Its aim is to support the growth of the photonics
sector in Canada. The Canadian government and the province of Ontario contributed CDN 30 million
(EUR 45 million)160 and CDN 13 million (EUR 19.5 million) respectively to the capital cost of the
building and equipment. The CPFC is located at the NRC laboratories and the NRC covered the
operating costs of the facility.
5.2.1.2 The United States of America (US)
The National Nanotechnology Initiative161 was launched in 2000 across a group of eight Federal
agencies with some responsibility for nanotechnology research, application and/or regulatory
activity, and has grown to include 25 Federal agencies. It aims to create collaborations and bring
together expertise to work on shared goals, priorities, and strategies thereby leveraging the
resources of the participating agencies. The goals of the NNI Goals are to advance world-class
nanotechnology research and development; foster the transfer of new technologies into products for
commercial and public benefit; develop and sustain educational resources, a skilled workforce and
the supporting infrastructure and tools to advance nanotechnology; and support the responsible
development of nanotechnology.
The NNI is managed within the framework of the National Science and Technology Council (NSTC),
a cabinet-level council under the Office of Science and Technology Policy at the White House. The
Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the NSTC facilitates
planning, budgeting, programme implementation and review across the NNI agencies. The National
Nanotechnology Co-ordination Office (NNCO) was established in 2001 to provide technical and
administrative support to the NSET Subcommittee, serve as a central point of contact for Federal
nanotechnology R&D activities and perform public outreach on behalf of the National Nanotechnology
Initiative.
The NSET Subcommittee is composed of representatives from agencies participating in the NNI and
156
http://www.nanoquebec.ca/media/plan-action_en1.pdf
157
Current conversion rates, October 2015.
158
http://www.promptinc.org/en/about-us/prompt-at-a-glance/
159
http://www.nrc-cnrc.gc.ca/eng/solutions/facilities/prototyping_index.html
160
Average rate 2005, CDN 1.5 to EUR 1.00 (www.x-rates.com )
161
http://www.nano.gov/
53
NanoData – Landscape Compilation - ICT
NSET has Working Groups on Global Issues in Nanotechnology; Nanotechnology Environmental &
Health Implications; Nano-manufacturing, Industry Liaison, & Innovation; and Nanotechnology
Public Engagement and Communications.
In February 2014, the National Nanotechnology Initiative released a Strategic Plan 162 outlining
updated goals and five "programme component areas" (PCAs). The goals focus on extending the
boundaries of research; fostering the transfer of technology into products; developing and sustaining
skilled people (with the right infrastructure and toolset) for nanotechnology; and supporting
responsible development of nanotechnology. The five PCAs include a set of five Nanotechnology
Signature Initiatives (NSIs) as well as PCAs for foundational research; nanotechnology-enabled
applications, devices, and systems; research infrastructure and instrumentation; and environment,
health, and safety. The five Nanotechnology Signature Initiatives (NSIs) are also relevant to ICT (for
example, nano-electronics, nanotechnology for sensors and sensors for nanotechnology.
The 2014 NNI Strategic plan also identifies the different priorities and interests of
departments/agencies, for example, nanotechnology and ICT are relevant to:
• Intelligence Community (IC)/Office of the Director of National Intelligence (ODNI) with reference
to ultralow-power non-volatile memory for saving power in data centres and satellites; and
• Department of Defence (DoD) (quantum information science, communications and information
processing systems needed for persistent surveillance).
The NNI's budget supplement proposed by the Obama administration for Fiscal Year 2015 provided
for USD 1.5 billion (EUR 1.2 billion163) of funding. Cumulative NNI investment since fiscal year 2001,
including the 2015 request, totals almost USD 21 billion (EUR 17 billion164). Cumulative investments
in nanotechnology-related environmental, health, and safety research since 2005 is nearly USD 900
million (EUR 680 million165). The Federal agencies with the largest investments are the National
Institutes of Health (NIH), the National Science Foundation (NSF), the Department of Energy, the
Department of Defence, and the National Institute of Standards and Technology (NIST).
Some of the above-mentioned institutions (like NIST, with its main focus on measurement sciences
and standards development) have areas dedicated to nanoscience and nanotechnology (for NIST
including nano-electronics and nanoscale electronics and nano-magnetics) as well as to information
technology and electronics and telecommunications166. The latter includes optoelectronics, quantum
information, semiconductors, sensors and microelectronics. Information Technology Manufacturing
at NIST167 encompasses subject areas including nano-manufacturing, green manufacturing, robotics,
systems integration, etc. NIST also provides facilities to support production, through the Centre for
Nanoscale Science and Technology (CNST)168, established in 2007. The CNST facilitates access to
commercial state-of-the-art nanoscale measurement and fabrication tools through its NanoFab. One
focus area is Future Electronics.
Another important actor active in nanotechnology is the NSF. This federal agency, with an annual
budget of USD 7.3 billion (EUR 6.8 billion169) (FY 2015), funds approximately 24% of all federally-
supported basic research (except for medical sciences) conducted by America's colleges and
universities170. With reference to the ICT sector, the Directorate for Computer & Information Science
&Engineering (CISE) is particularly relevant, dealing with advanced cyber-infrastructure, computing
and communications foundations, computer and networks systems, and information and intelligent
systems. CISE is also leader of the National Strategic Computing Initiative (NSCI)171 in collaboration
with academia and industry, aiming at maximising “benefits of high-performance computing (HPC)
research, development, and deployment”. Also the Directorate of Engineering (ENG), Division
Electrical, Communications and Cyber Systems Division (ECCS) is active in the field of ICT, in
162
http://www.nano.gov/sites/default/files/pub_resource/2014_nni_strategic_plan.pdf
163
Average yearly conversion rate, 2015 (source: www.wolframalpha.com )
164
Average yearly conversion rate, 2001-2015 (source: www.wolframalpha.com )
165
Average yearly conversion rate, 2005-2015 (source: www.wolframalpha.com )
166
http://www.nist.gov/electronics-and-telecommunications-portal.cfm
167
http://www.nist.gov/manufacturing-portal.cfm
168
http://www.nist.gov/cnst/index.cfm
169
Current conversion rate, November 2015 (source: www.wolframalpha.com )
170
http://www.nsf.gov/about/
171
https://www.whitehouse.gov/the-press-office/2015/07/29/executive-order-creating-national-strategic-
computing-initiative
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NanoData – Landscape Compilation - ICT
particular with the programmes on electronics, photonics and magnetic devices (EPMD) and
communications, circuits, and sensing-systems (CCSS).
In additional to these Federal initiatives, there exist several policy initiatives at State level172.
Programmes for the promotion of nanotechnologies currently exist in 23 states. Notable examples
are the Texas Emerging Technology Fund173, the Oklahoma Nanotechnology Initiative174, the Illinois
Nanotechnology “Collaboratory”175, and the Oregon Nanoscience and Micro-Technologies Institute
(ONAMI)176. The State-level organisations typically undertake some or all of the following activities:
fostering collaboration on nanotechnology topics and challenges between researchers and research
centres; higher education/industry joint projects; education and outreach; access to technology
experts and infrastructure; early-stage funding and investment opportunities; technology transfer
and commercialisation; and awareness raising in the community.
Finally, an international industry-led initiative relevant for ICT is sponsored by the United States
Semiconductor Industry Association (SIA)177 together with the European Semiconductor Industry
Association (ESIA), the Japan Electronics and Information Technology Industries Association (JEITA),
the Korean Semiconductor Industry Association (KSIA) and the Taiwan Semiconductor Industry
Association (TSIA). They drafted the International Technology Roadmap for Semiconductors178 “to
ensure cost-effective advancements in the performance of the integrated circuit and the advanced
products and applications that employ such devices”. 179 The Roadmap focuses on devices (including
3D power scaling, edgeless wrapped materials and CMOS), system integration (e.g. spinwave
devices) and manufacturing (related to nano integrated circuits and big data).
172
http://www.nano.gov/initiatives/commercial/state-local
173
http://gov.texas.gov/. As of October 2010, the Texas Emerging Technology Fund has given a total of UDS
173 million to 120 companies as well as UDS 161 million to educational institutions.
174
http://www.oknano.com /
175
http://nano.illinois.edu/collaboration/index.html
176
http://onami.us/
177
http://www.semiconductors.org/
178
http://www.semiconductors.org/news/2014/04/01/press_releases_2013/international_technology_roadmap
_for_semiconductors_explores_next_15_years_of_chip_technology/
179
http://www.itrs.net/about.html
180
http://www.agencia.mincyt.gob.ar/frontend/agencia/fondo/agencia
181
http://www.fan.org.ar/en/
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NanoData – Landscape Compilation - ICT
Innovadora 2020 (Innovative Argentina Plan 2020): National Plan of Science, Technology and
Innovation. The plan focuses on three general-purpose technologies (nanotechnology, biotechnology
and information and communication technology (ICT)) addressing six strategic groups, including
industry.
5.2.2.2 Brazil
Systematic policy support for nanotechnology started in 2001, when the Brazilian Ministry of Science
and Technology (MCT) through the Brazilian National Research Funding Agency (Conselho Nacional
de Desenvolvimento Científico e Tecnológico or “CNPq”) earmarked BRL 3 million (USD 1 million)
(EUR 1.12 million182) over four years to form Co-operative Networks of Basic and Applied Research
on Nanosciences and Nanotechnologies. Four national research networks were established:
semiconductors and nano-structured materials; nano-devices; molecular nanotechnologies and
interfaces; and nano-biotechnology. In late 2004, a network on Nanotechnology, Society and
Environment was created that was independent of the formal funding mechanisms.
Since 1999, Brazil’s national plan has comprised an annual budget and a four-year strategic plan
(the Plano Plurianual or PPA). In 2003, the Ministry created a special division for the general co-
ordination of nanotechnology policies and programmes whose work resulted in a proposal for specific
nanotechnology-related funding. That proposal was taken up in the PPA in 2004-2007, which
provided for BRL 78 million (c. USD 28 million) (EUR 22 million183) over 4 years for the Programme
for the Development of Nanoscience and Nanotechnology. The aim of the programme was “to
develop new products and processes in nanotechnology with a view to increasing the
competitiveness of Brazilian industry”, which it implemented by supporting networks, research
laboratories and projects.
A review of the funding in the light of the 2004 policy on Industrial, Technological and Foreign Trade,
the government reconsidered the original budget and increased Federal investment for 2005 and
2006 from the original USD 19 million (EUR 15 million184) to c. USD 30 million (EUR 24 million185)
for those two years. Ten new research networks were set up to continue previous research activities
but linking more closely to broader industry, technology, and trade policies. Industrial policy helped
to reinforce the strategic status attributed at national level to nanotechnology and its role in
enhancing Brazil’s competitiveness. Of particular important in the programmes were the
development of qualified human resources, the modernisation of infrastructure and the promotion
of university-industry co-operation.
In 2012, the Brazilian Ministry for Science, Technology and Innovation (MCTI) launched the
SisNANO186 initiative, enabling scientists throughout Brazil to conduct experiments at 26 “open”
laboratories offering the very best equipment for research in nanotechnology. University students
and staff can use the facilities free of charge – provided that they submit a good research proposal
– while scientists working in industry are able to access specialist equipment and expertise at highly
subsidised rates. The laboratories offer facilities fundamental for improving for example, electron-
spinning. A laboratory quite related to ICT sector is the Centre for Semiconductor Components, CCS,
focused on “nano-electronics, nano-photonics and micro-electronics”.187
In 2013, MCTI launched the Brazilian Nanotechnology Initiative (IBN) with funding estimated to be
BRL 440 million (EUR 148 million188) for the 2013-2014 period. The implementation of IBN was an
effort to further strengthen nanotechnology in Brazil by strengthening academic and industry
linkages thereby to promote the scientific and technological development of the nanotechnology
sector.
182
Average yearly conversion rate, 2001(source: www.wolframalpha.com)
183
Average yearly conversion rate, 2004-2007 (source: www.wolframalpha.com)
184
Average yearly conversion rate, 2005-2006 (source: www.wolframalpha.com)
185
Average yearly conversion rate, 2005-2006 (source: www.wolframalpha.com)
186
Sistema Nacional de Laboratórios em Nanotecnologias ftp://ftp.mct.gov.br/Biblioteca/39717-SisNANO.pdf
187
http://www.ccs.unicamp.br/novosite/en/
188
Average yearly conversion rate, 2013-2014(source: www.wolframalpha.com )
56
NanoData – Landscape Compilation - ICT
5.3 Asia
189
The programme is named for its date, the 86 for 1986 and the 3 for the third month, hence 86/3 or 863.
Likewise for the 973 programme launched in March 1997.
190
http://www.chinaembassy.bg/eng/dtxw/t202503.htm
57
NanoData – Landscape Compilation - ICT
191
Average yearly conversion rate, 2001 (source:
www.europarl.europa.eu/RegData/etudes/note/join/2007/379231/IPOL-
TRAN_NT%282007%29379231_EN.pdf )
192
Average yearly conversion rate, 2005 (source:
www.europarl.europa.eu/RegData/etudes/note/join/2007/379231/IPOL-
TRAN_NT%282007%29379231_EN.pdf )
193
https://www.jsps.go.jp/english/e-quart/17/jsps17.pdf
194
Average yearly conversion rate, 2006 (source:
www.europarl.europa.eu/RegData/etudes/note/join/2007/379231/IPOL-
TRAN_NT%282007%29379231_EN.pdf )
195
http://www.nstc.go.kr/eng/
58
NanoData – Landscape Compilation - ICT
Development Plan was approved by the NSTC on in July 2001 and the NT Development Promotion
Act passed in November 2002 by the National Assembly. The initiative is now in its 3 rd phase (2011-
2020), with focus on ‘clean nanotech’. Investment in phase 1 (2001-2005) was 105.2 billion Won
(EUR 83 million196); phase 2, 277.2 billion Won (EUR 1,541.8 million197).
Under its KNNI, Korea has focused on establishing specific support mechanisms (programmes,
systems and societies) and centres of excellence across the country. The launching of the National
Programme for Tera-Level Nano-devices (2000) was followed by the founding of the Nanotechnology
Industrialisation Support Centre (2001) and the Korean Advanced Nanofabrication Centre 198 (KANC)
(2003). In more recent times, building on former centres, Korea established two NST centres at the
Institute for Basic Science: the Centre for Nanoparticle Research and the Centre for Nanomaterials
and Chemical Reactions (2012)199. In total, 24 nanotechnology-related centres now exist in Korea.
The Korean Institute of Science and Technology (KIST)200 has a Material and Life Science Division,
covering nanotechnology, ICT and biotechnology. Also related to ICT and nanotechnology at KIST,
the Post-silicon Semiconductor Institute has a specialised Centre for Spintronics as well as a Centre
for Electronic materials, a Centre for Opto-Electronic Materials and Devices, and a Centre for
Quantum Computing201. In addition, by 2010, over forty universities had nanotechnology
departments.
Under the Nanotechnology Development Promotion Act 2002, Korea also established in 2004 the
Korean Nano Technology Research Society (KoNTRS)202 as a mechanism for co-operation between
researchers working on nanotechnology throughout the country, to develop collaborative research
programmes between institutions (public and private) and to support the government in establishing
appropriate national NST policies.
Korea has since continued to invest in nanotechnology, with the review by NSTC in 2006 of the first
five years of its NNI leading to support continuing for an additional ten years. In this third phase of
the NT Development Plan (2011-2020), there is greater focus on clean nanotechnology and overall
the policy has evolved, moving away from funding fundamental research towards more application-
driven actions.203
Korea has also sought to develop its nanotechnology policy and policy system, with the production
of the Korean Nanotechnology Roadmap in 2008 and the establishment of the National
Nanotechnology Policy Centre (NNPC) in 2010. The NNPC announces on its web site204 the national
vision for Korea to be “the world’s number one nanotechnology power” and the four goals:
• “To become a leading nation in nanotechnology with systematic nanotechnology R&D
programmes;
• To create a new industry based on nanotechnology;
• To enhance social and moral responsibility in researching and developing nanotechnology; and
• To cultivate advanced nanotechnology experts and maximise the utilisation of nanotechnology
infrastructure.”
Mid-term and long-term strategies for nanotechnology in Korea, which have been developed and
implemented since about 2009, include:
• The Fundamental Nanotechnology Mid-term Strategy [NT 7-4-3 Initiative] through which the
Ministry of Education, Science and Technology (MEST) supported 35 green nanotechnologies in
seven areas as well as funding four infrastructure projects;
196
Average yearly conversion rate, 2001-2005 (source:
www.ecb.europa.eu/stats/exchange/eurofxref/html/eurofxref-graph-krw.en.html )
197
Average yearly conversion rate, 2006-2010 (source:
www.ecb.europa.eu/stats/exchange/eurofxref/html/eurofxref-graph-krw.en.html )
198
http://www.kanc.re.kr/kancEnglish/center/center_overview.jsp
199
https://www.ibs.re.kr/eng/sub02_04_03.do
200
KIST is a science and technology institute. It was the first S&T research institute founded in Korea following
the joint statement by the Presidents of Korea and the US on the “Establishment of a Korean Industrial
and Applied Science R&D Institute” (1966) http://eng.kist.re.kr/kist_eng/?sub_num=728
201
http://eng.kist.re.kr/kist_eng/?sub_num=1596
202
http://kontrs.or.kr/english/index.asp
203
http://www.nanotechmag.com/nanotechnology-in-south-korea/
204
http://www.nnpc.re.kr/htmlpage/15/view
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NanoData – Landscape Compilation - ICT
• The Nano Fusion Industry Development Strategy by MEST and the then Ministry of the
Knowledge Economy (MKE), which sought to support nanotechnology all across the value chain,
from the research laboratory to the marketplace;
• The National Nano Infrastructure Revitalisation Plan, also by MEST and MKE, to link
nanotechnology infrastructures together, thereby giving them new impetus; and
• The Nano Safety Management Master Plan 2012-2016 to define methods and processes for the
identification and manage any safety risks that emerge with the development, commercialisation
and manufacture of nanotechnology products.
2012 saw the creation of the Nano-Convergence Foundation (NCF)205 whose remit is to increase the
commercialisation of national NST research outcomes. It operates under the joint support of the
Ministry of Science, ICT & Future Planning (MSIP) and the Ministry of Trade, Industry & Energy
(MOTIE). Korea plans to invest 930 billion Korean Won (ca. USD 815 million, EUR 740 million206) by
2020 in the NST, with projects in the Nano Convergence 2020 programme eligible to receive up to
2 billion Korean Won (EUR 1.5 million207) each.
5.3.1.4 Taiwan (Chinese Taipei)208
The National Nanoscience and Nanotechnology Programme209 was approved for a period of six years
by the National Science Council (NSC) in 2002. With a budget envelope of USD 700 million (EUR
740 million210) and actual expenditure estimated to be USD 625 million (EUR 486 million211) over
2003-2008, the aim of the programme was to foster nanotechnology research and development in
research institutes, universities and private companies, achieving academic excellence and
supporting commercialisation. The Academic Excellence part of the programme includes physical,
chemical and biological properties of nano-sensors, nano-structures, nano-devices and nano-
biotechnology. Industrial applications are the remit of the Industrial Technology Research Institute
(ITRI). ITRI has 13 research laboratories and centres in areas including optoelectronics, electronics,
mechanical and systems, applied materials, biomedicine, chemistry and mechanics. The Information
and Communications Research Laboratories212 and the Electronic and Optoelectronic System
Research Laboratories are relevant for the ICT sector.213 The latter, in particular, conducts research
in new semiconductor architectures, including advanced memories, 3D-IC and ultra-fine line, and
embedded-interposer-carrier substrates.
The National Nanoscience and Nanotechnology Programme also co-ordinates the nanotechnology
research efforts of government agencies mainly through the establishment of common core facilities
and education programmes, by promoting technology transfer and commercialisation into industrial
applications and establishing internationally competitive nanotechnology platforms. Among the
thematic priorities of the programme overall have been the design and fabrication of interconnects,
interfaces and system of functional nano-devices, and the development of MEMS/NEMS technology.
Taiwan’s Nanotechnology Community (NTC) was established in 2003 to identify commercial
applications of nanotechnology and, in 2004, the Taiwan Nanotechnology Industrialisation Promotion
Association (TANIPA) was set up by the Industrial Development Bureau at the Ministry of Economic
Affairs (MOEA), with a strategic remit related to industrial applications of nanotechnology and to
facilitate public-private co-operation.
Phase I of the National Nanoscience and Nanotechnology Programme was completed in 2008. Phase
II was approved by the NSC in April 2008 to run for another six years (2009-2014) with the goal of
strengthening and concentrating public resources on “Nanotechnology Industrialisation”, i.e. the
development of nanotechnology for domestic industry relevant to Taiwan and its growth into high-
tech industry. Building on Phase I, Phase II has supported nano-instrumentation, nano-
optoelectronics, nano-electrics, energy and environmental nanotechnology, nano-materials and
205
http://www.nanotech2020.org/download/english_brochure.pdf
206
Current exchange rate, November 2015 (source: www.wolframalpha.com )
207
Current exchange rate (November 2015) (source:
www.ecb.europa.eu/stats/exchange/eurofxref/html/eurofxref-graph-krw.en.html )
208
http://www.twnpnt.org/
209
http://www.twnpnt.org/english/g01_int.asp
210
Average yearly conversion rate, 2002 (source: www.wolframalpha.com )
211
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768287/
212
https://www.itri.org.tw/eng/Content/Messagess/contents.aspx?SiteID=1&MmmID=617766557770066341
213
https://www.itri.org.tw/eng/Content/Messagess/contents.aspx?SiteID=1&MmmID=617751557022321307
60
NanoData – Landscape Compilation - ICT
214
http://www.oecd.org/science/nanosafety/37277620.pdf; http://nanomission.gov.in/;
http://www.ris.org.in/images/RIS_images/pdf/DP%20193%20Amit%20Kumar.pdf,
http://erawatch.jrc.ec.europa.eu/erawatch/opencms/information/country_pages/in/country?section=Resea
rchPolicy&subsection=ResPolFocus
215
Average yearly conversion rate, 2002-2006 (source: www.wolframalpha.com)
216
http://nanomission.gov.in/;
217
http://timesofindia.indiatimes.com/home/science/Govt-approves-Rs-650-crore-for-Nano-
mission/articleshow/30722422.cms
218
www.csir.res.in/
219
http://www.csir.res.in/external/heads/collaborations/NM.pdf
220
http://www.teriin.org/div/ST_BriefingPap.pdf
221
www.dst.gov.in/about_us/ar05-06/serc.htm
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NanoData – Landscape Compilation - ICT
interdisciplinary research. Support for nanotechnology projects has been provided through its
R&D schemes for basic science and engineering science.
5.3.2.2 Iran222
The Islamic Republic of Iran ranked 23rd in the world in nanotechnology in 2007, second to Korea in
citations in Asia223, but, by 2012, it had moved to 10th place224, 225. In 2013, Iran ranked 20th in
science production in the world (Thomson Reuters) and 18 th in science production for medicine.
According to the Ministry, its share of global science production rose from 1.39% in 2013 to 1.69%
percent in 2014, as measured by indicators including the number of scientific papers, the quality
and quantity of documents, patenting inventions, industrial plans, partnership with foreign
universities, and the use of technology in domestic organisations.
There are nine scientific committees responsible for organising and coordinating science activities in
Iran including committees for nanotechnology, biotechnology, aerospace, information technology,
renewable energies and environment.
Iran began its nanotechnology activities with a Study Committee for Nanotechnology in 2001. Its
work led to the development of the Iran Nanotechnology Initiative Council (INIC)226, established in
2003 to develop policies to foster nanotechnology in Iran and monitors their implementation. The
Council also funds researchers, having supported over 1400 researchers for nanotechnology activity
between 2004 and 2010, at a cost of USD 12 million227 (EUR 9 million228).
INIC has also funded the development of research and training facilities for nanotechnology
research, such as the Institute for Nanoscience and Nanotechnology (INT) at the Sharif University
of Technology. The INT, established in 2004, was the first institute to offer a PhD in nanotechnology
in Iran229. INIC undertakes education and awareness-raising activities including a students’ Nano
Club, seminars, workshops, publications and a multi-lingual (Arabic, Persian, Russian and English)
website230.
Also in 2004, INIC was instrumental in establishing the Iran Nanotechnology Laboratory Network to
optimise Iran’s nanotechnology infrastructure. Forty-two laboratories across Iran operate under the
network. The role of INIC includes evaluation and ranking of member laboratories and providing
support for them in areas such as training workshops, lab equipment, and in gaining accreditation
as testing and calibration labs.
INIC operates through working groups on areas including Human Resource Development;
Technology Development and Production; and Education and Awareness. It also addresses standards
and regulations through the Iran Nanotechnology Standardisation Committee (INSC) 231, a body
established in 2006 as a collaboration between the INIC and the Institute of Standard and Industrial
Research of Iran (ISIRI)232.
Continuing to support nanotechnology and the work of INIC, a “Future Strategy” was adopted in
2005 by the Cabinet, a 10-year nanotechnology development (2005 - 2014). Its mission was to
place Iran among the top fifteen advanced countries in nanotechnology in the world. The focus was
placed on building and using infrastructure and human resources; improving communication and
networking both within Iran and internationally; and generating economic added value from
nanotechnology as a means of achieving economic development233.
222
See also http://www.sciencedev.net/Docs/Iran_Nano.pdf (2010)
223
http://webarchive.nationalarchives.gov.uk/20090609003228/http://www.berr.gov.uk/files/file11959.pdf
224
http://statnano.com/report/s29
225
http://www.nanotech-now.com/news.cgi?story_id=45237
226
http://nano.ir/index.php?lang=2
227
http://www.nanotech-now.com/news.cgi?story_id=36557
228
Average yearly conversion rate, 2004-2010 (source: www.wolframalpha.com )
229
http://blogs.scientificamerican.com/guest-blog/science-and-sanctions-nanotechnology-in-iran/
230
http://nano.ir/index.php?ctrl=static_page&lang=2&id=397§ion_id=22
231
http://nanostandard.ir/index.php?lang=2
232
http://www.isiri.com/
233
http://statnano.com/strategicplans/1
62
NanoData – Landscape Compilation - ICT
234
http://www.mosti.gov.my/en/about-us/divisions-departments/national-nanotechnology-directorate-division-
nnd/
235
http://www.nanomalaysia.com.my/index.php?p=aboutus&c=whoweare
236
http://inee.unimap.edu.my/
237
www.ukm.my/
238
http://www.techmonitor.net/tm/images/d/d1/10jan_feb_sf3.pdf
239
http://nanotech.apctt.org/countryreports/Philippines%20Country%20Report.pdf
240
https://www.mti.gov.sg/ResearchRoom/Pages/Science-and-Technology-Plan-2010.aspx
241
www.edb.gov.sg
242
www.ida.gov.sg
63
NanoData – Landscape Compilation - ICT
243
www.a-star.edu.sg/
244
http://www.a-star.edu.sg/dsi/Home.aspx
245
http://www.a-star.edu.sg/ihpc/Research/Overview.aspx
246
https://www.a-star.edu.sg/ime/
247
http://www.a-star.edu.sg/Media/News/Press-Releases/ID/1363/ASTAR-SIMTech-Nanotechnology-in-
Manufacturing-Initiative-NiMI-to-Overcome-Challenges-to-Tap-Market-Potential.aspx
248
http://www.nanotec.or.th/th/wp-content/uploads/2013/05/NANOTEC-brochure11.pdf
249
http://www.nanotec.or.th/en/wp-content/uploads/2012/02/The-National-Nanotechnology-Policy-framework-
exe-sum.pdf
250
http://www.nanotec.or.th/en/
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251
http://www.nanoisrael.org/
252
http://www.trdf.co.il/eng/fundinfo.php?id=2846
253
http://www.economy.gov.il/English/Pages/default.aspx
254
http://www.moital.gov.il/NR/exeres/111E3D45-56E4-4752-BD27-F544B171B19A.htm
The Magnet programme supports companies and academics to form consortia to research precompetitive
generic technologies. Direct funding is up to 66% of the cost of the project with no obligation to repay
royalties.
255
Average yearly conversion rate, 2012 (source: www.wolframalpha.com )
256
Average yearly conversion rate, 2012 (source: www.wolframalpha.com )
257
Figures for funding under the programme to 2012.
258
http://www.nanoisrael.org/category.aspx?id=1278
259
Average yearly conversion rate, 2006 (source: www.wolframalpha.com)
260
The Technion centre was co-funded by the Russel Berrie Foundation via a donation of USD 26 million which,
together with funding from Technion itself, the Office of the Chief Scientist and the Ministry of Finance,
made up to USD 78 million for the Russell Berrie Institute for Research in Nanotechnology.
261
Israel Institute of Technology http://www.technion.ac.il/en/
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and also has a specialisation in sol-gel-based nanomaterials. Work is also taking place at the Institute
of Nanotechnology and Advanced Materials at Bar-Ilan University in several areas, including
computers.262 Furthermore, photonics and electronics is among the research activities of the Ilse
Katz Institute for Nanoscale Science & Technology, at Ben-Gurion University, with a specialisation
in design, simulation and fabrication of nano-photonic chips and devices.263
To help academics and industry to access the facilities of the six Israeli nano centres, the INNI has
made available a national nano infrastructure catalogue264. The catalogue of equipment includes
pricing for the use of the equipment and contact information. Industry users are supported by the
university nano-centres to enable them to be effective in using their R&D equipment.
INNI also has introduced the Industry-Academia Matchmaking programme to make Israeli
nanotechnology more visible to the industrial and investment communities and to promote Israel’s
NST research capabilities to potential partners. Experts help potential collaborators to meet, access
expertise and access funding depending on their needs. They engage with key nanotechnology
stakeholders in Israel and abroad, initiate and managing national and international networks in NST.
They also gather statistics and market information on NST.
5.3.4.2 Saudi Arabia265
The King Abdul Aziz City for Science and Technology (KACST) was established in 1985 as the
Kingdom’s main agency for promoting research and development. In 2002, Saudi Arabia decided to
build further on the work of KACST by putting in place a National Policy for Science and Technology
(NPST) with plans to increase R&D funding to 1.6% of GDP. KACST was made responsible for
implementing the policy which included five-year strategic plans (missions) in eleven research areas
prioritising areas relevant to ICT including nanotechnology and information technology, electronics,
photonics, advanced materials, as well as others: water, oil and gas, petrochemicals, biotechnology,
space and aeronautics, energy and environment. The National Nanotechnology Programme (NNP)
was established to deliver the plan.
During the implementation of the NNP, nanotechnology centres began to be established, such as the
Centre of Excellence in Nanotechnology (CENT) established 2005 at the KFUPM 266; and the CNT
established in 2006 at the KAU267 that covers the fields of electromechanical (MEMS/NEMS) devices,
semiconductors nanomaterials and computational nanotechnology. These centres operated in the
context of the multidisciplinary programme of Strategic Priorities for Nanotechnology 2008-2012,
put in place by the Saudi Arabian Ministry of Economy and Planning in 2008.
Additional nanoscience and nanotechnology centres followed. The Centre of Excellence of Nano-
manufacturing Applications (CENA) was established in 2009 at KACST (active in the area of
fabrication of sensors) and the King Abdullah Institute for Nanotechnology (KAIN)268 established in
2010 at the KSU in the Riyadh Techno Valley. The KAIN covers areas including telecommunications,
manufacturing of nanomaterials, energy, medicine and pharmaceuticals, food and environment, and
water treatment and desalination. Companies also collaborate on nanotechnology research with the
nanotechnology centres.
5.3.4.3 Turkey
Nanotechnology was one of eight strategic fields of research and technology identified in the Vision
2023 Technology Foresight Study prepared by the Turkish Supreme Council of Science and
Technology (SCST) in 2002. The Foresight Study formed part of the development of the National
Science and Technology Policies 2003-2023 Strategy Document. In nanotechnology, seven thematic
priority areas were selected: (i) nano-sized quantum information processing; (ii) nano-photonics,
nano-electronics and nano-magnetism; (iii) nanomaterials; (iv) nano-fabrication; (v) nano-
biotechnology; (vi) nano-characterisation; and (vii) fuel cells and energy. Nanotechnology was also
included as a priority technology field in the Development Programme prepared by State Planning
262
http://nano.biu.ac.il/research-centers/nano-materials
263
http://in.bgu.ac.il/en/iki/Pages/Research-Activity1.aspx
264
http://www.nanoisrael.org/category.aspx?id=13671
265
A review of nanotechnology development in the Arab World, Bassam Alfeeli et al., Nanotechnology Review,
2013 (05/2013; 2(3):359-377)
266
King Fahd University of Petroleum and Minerals, Riyadh
267
King Abdul Aziz University, Jeddah
268
http://nano.ksu.edu.sa/en
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5.4 Oceania
5.4.1.1 Australia
The National Nanotechnology Strategy (NNS) was put in place in 2007 by the Australian Department
of Innovation, Industry, Science and Research as a dedicated strategy for nanotechnology, 2007 to
2009. The Australian Office of Nanotechnology was established to co-ordinate the strategy and
ensure a whole-of-government approach to nanotechnology issues. A Public Awareness and
Engagement Programme formed part of the NNS.
In 2009-2010, the NNS was replaced with a National Enabling Technology Strategy (NETS), a
comprehensive national framework for the safe and responsible development of novel technologies
(including nanotechnology and biotechnology). With funding over four years of AUS 38.2 million
(EUR 28.3 million275), the strategy aimed to ensure good management and regulation of enabling
technologies in order to maximise community confidence and community benefits from the
commercialisation and use of new technology. Public engagement has remained an important topic
in Australia for nanotechnology and other novel technologies.
In 2012, the National Nanotechnology Research Strategy276 was prepared by the Australian Academy
of Science, using funding received from the National Enabling Technologies Policy Section in the
Department of Industry, Innovation, Science, Research and Tertiary Education. The Research
Strategy highlighted the importance of developing the nanofabrication capabilities necessary to have
a major impact on all areas of information and communication technology (ICT), for example,
through the fabrication of quantum/nanoscale photonic, electronic and electromechanical structures.
In addition, it identified Australia as being a world leader in optical fibres (through its Institute for
Photonics and Advanced Sensing277, Institute of Photonics and Optical Science278 and Australian
National Fabrication Facility (ANFF)279). The Strategy also identifies Australian strengths in the
fabrication of nanomaterials relevant to ICT: structures on silicon (SoS) for nano-electronics and
quantum computing applications; fabrication of III-V quantum dots, nanowires, metamaterials,
plasmonic structures and photonic crystals for applications in electronics and photonics, including
novel sensors; nanostructured glasses for novel optical fibres used for sensors and ICT applications;
novel MEMS and nanostructures in II-VI semiconductors and germanium for applications in sensors,
nano-photonics and nano-electronics.
More generally, the Strategy set out a vision for Australia to become a world leader in a
nanotechnology-driven economy with a strong nanotechnology research base and the means to
assist industry to revolutionise its portfolio through nanotechnology, for greater competiveness and
to address the grand challenges most relevant to Australia. The Strategy highlighted the importance
of infrastructure, interdisciplinary research, international engagement, the translation of research
269
http://www.issi2015.org/files/downloads/all-papers/0720.pdf
270
Average yearly conversion rate, 2007-2014 (source: www.wolframalpha.com )
271
http://www.nanotam.bilkent.edu.tr/eng/main.html
272
http://unam.bilkent.edu.tr/?page_id=576
273
http://sunum.sabanciuniv.edu/
274
http://mnt.metu.edu.tr/
275
Average yearly conversion rate, 2010-2013 (source:
https://www.ecb.europa.eu/stats/exchange/eurofxref/html/eurofxref-graph-aud.en.html )
276
https://www.science.org.au/publications/national-nanotechnology-research-strategy
277
http://www.adelaide.edu.au/ipas/about/role/
278
http://sydney.edu.au/ipos/
279
http://www.anff.org.au/
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5.5 Africa
5.5.1.1 South Africa
Since 2002, the Republic of South Africa has launched several national nanotechnology initiatives to
strengthen national capabilities in this field. Relevant steps have included:
• In 2002, the formation of the South African Nanotechnology Initiative (SANi)286 with membership
comprising academics, researchers, engineers, private sector companies, and research councils;
• In 2003, the launch of South Africa’s Advanced Manufacturing Technology Strategy (AMTS) 287
by the Department of Science and Technology (DST);
• In 2005, the publication of the National Strategy on Nanotechnology (NSN) 288 by the DST. The
strategy focuses on four areas:
280
http://www.ausnano.net/index.php?page=home
281
http://www.macdiarmid.ac.nz/
282
Average yearly conversion rate, 2003-2006 (source: www.wolframalpha.com )
283
http://www.macdiarmid.ac.nz/a-nanotechnology-initiative-for-new-zealand/
284
http://statnano.com/strategicplans/13
285
http://www.mbie.govt.nz/
286
http://www.sani.org.za/
287
http://www.esastap.org.za/download/natstrat_advmanu_mar2005.pdf
288
http://chrtem.nmmu.ac.za/file/35e56e36b6ab3a98fac6fc0c31ee7008/dstnanotech18012006.pdf
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289
http://www.csir.co.za/
290
http://www.nic.ac.za/
291
http://ls-ncnsm.csir.co.za/
292
http://www.ibsa-trilateral.org/
293
http://www.ibsa-trilateral.org/about-ibsa/areas-of-cooperation/people-to-people
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There has been a high level of growth in ICT publications as indexed to the year 2000. For the World,
there has been almost a ten-fold growth while for the EU28&EFTA, it is around a six-fold growth.
294
http://www.vosviewer.com/Publications
295
Search included all those publications having been produced with “nano” as a core term. The term
“nanosecond” has been omitted as not being relevant to the study.
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Looking at the EU28&EFTA proportion of world output on ICT, it is seen to have decreased over time,
as shown below. This is mainly caused by a sharp increase in the output from China.
Figure 6-2: NST ICT publications as a percentage of NST World total, 2000-2014
The table below shows the most important journals in which researchers in this sector published
their results. The results show a clear preference for the top four journals.
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Table 6-2: Most common journals by numbers of NST ICT publications (npub), 2000-2014
Region npub
Asia 14,303
EU28&EFTA 5,411
North America 5,001
Middle East 693
Oceania 645
The most prolific country for ICT publications globally in 2014 was China (PRC), followed by the US,
South Korea, Japan, Germany and India, as shown below.
Figure 6-3: Number of NST ICT publications by country (top 9), 2014
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In the EU28&EFTA, Germany generated the largest number of publications in 2014, followed by the
United Kingdom, France, Italy and Spain, as shown below.
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The higher education organisations (EU28&EFTA) with the most ICT publications in 2014 were the
University of Cambridge, EPFL296, University of Paris XI Sud, IMEC297 and the Technical University of
Dresden, as shown in the table below of the top ten NST publishing organisations for ICT
publications.
296
École Polytechnique Fédérale de Lausanne
297
Interuniversitair Micro-Elekctronica Centrum Vzw
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Table 6-6: Number of ICT publications by EU&EFTA organisation (top ten), 2014
The companies with the most ICT publications globally in 2014 were IBM, Samsung Electronics Co.
Ltd., and Nippon Telegraph (NTT) shown in the table of the top ten publishing companies below.
Table 6-7: Number of ICT publications by company (top 8), 2014
Company npub
IBM Corporation 91
Samsung Electronics Co. Ltd. 45
Nippon Telegraph (NTT) 37
Intel Corporation 31
STMicroelectronics SA 29
Samsung Advanced Institute of Technology 29
Polyera Corporation 18
Diamond Light Source Ltd 16
Hewlett Packard Corporation 14
The next section looks at patenting activity in nanotechnology and ICT, over time, by country of
applicant, by applicant organisation and by patents granted.
298
École Polytechnique Fédérale de Lausanne
299
Interuniversitair Micro-Elekctronica Centrum Vzw
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7.2 Number and evolution over time of ICT nanotechnology patent families
Using the above methodology, 45,127 (simple) nanotechnology patent families 303, 304 of granted
patents and patent applications were found in the period 1993-2011305. All were from the European
Patent Office (EPO or EP), US Patent and Trademark Office (USPTO or US) or the World Intellectual
Property Organisation (WIPO)306.
In the same period, the number of ICT-related patent families identified among the nanotechnology
patents is 5,536, 12.3% of all nanotechnology patent families. As applications may have been filed
with multiple authorities, the percentages for PCT, EP and US do not sum to 100%. The highest
percentage of applications relating to ICT and nanotechnology is in the US (91.8%) and the lowest
at the EPO (35.4%), the difference being almost a factor of three.
Table 7-1: Absolute numbers and percentages of patents on ICT and nanotechnology
300
Thus all patent documents including at least one of the keywords (in title or abstract) was found but only
when the patent was classified as being related to at least one of the sectorial IPC codes.
301
http://www.wipo.int/pct/en/
302
By filing one international patent application under the PCT, applicants can simultaneously seek protection
for an invention in 148 countries throughout the world.
http://www.wipo.int/pct/en/pct_contracting_states.html
303
The definition of simple family is used, in which all documents having exactly the same priority or
combination of priorities belong to one patent family (http://www.epo.org/searching/essentials/patent-
families/definitions.html ). The patent families include at least one PCT, EPO or USPTO patent application.
304
A patent family is defined by WIPO (the World Intellectual Property Organisation) as a set
of patent applications inter-related by either priority claims or PCT national phase entries, normally
containing the same subject matter. http://www.wipo.int/
305
This year refers to the oldest year of the priority patents.
306
While patents can be filed in individual patent offices, many inventors choose to file applications under the
Patent Classification Treaty (PCT). All WIPO applications are PCT applications.
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Figure 7-1: Number of patent families by filing authority (PCT, EPO, and USPTO)
The figure below shows the evolution over time of patent applications to WIPO (PCT), the EPO or
USPTO as measured by the percentage of patent families.
Figure 7-2: Evolution over time of WIPO (PCT), EPO and USPTO ICT nanotechnology
patenting
The percentage of ICT nanotechnology patent applications in the EPO has dropped significantly over
time, while the percentage has been more stable for USPTO and PCT filings 307. This trend may
indicate that patent filing in the US has remained important while the importance of filing in Europe
has decreased.
307
It should be noted that the cost of applying for a US patent for an extended market is low compared with an
EPO patent. There is less scrutiny of a US patent and there is evidence that a higher proportion of US
patents are granted for inventions that are not novel, resulting in litigation later.
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figure of the lowest European country in the table (France, 59), the total for the EU28 plus the EPO
is less than the US.
Table 7-2: Number of nanotechnology ICT patent families by PCT receiving authority
Applicants may file patents with more than one patent authority, e.g. at the USPTO and as at the
EPO. The table below shows the data for the top 25 countries of applicants, as well as indicating the
percentage of patent families for each. EU28 and EFTA countries are marked in bold. As patents may
be filed with more than one authority (including PCT, US and EP applications), the percentages can
sum to more than 100%.
By far the highest number of patent families is found where the country of the applicant is the US,
followed by two Asiatic countries (Japan and, at considerable distance, Korea). Following these
countries, there are European countries with a relatively high number of patent families: Germany
(330), and then the Netherlands, the United Kingdom and France with between 175 and 200 patent
families each.
Among the countries in the table with lower number of patent families, there are also several
European countries, such as Austria (10) and Ireland (8).
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Table 7-4: Patent families by country of applicant, numbers and percentages (1993-2011)
More than 98% of patents by US applicants are filed with the USPTO while roughly 60% are filed as
PCTs. Only 39% are filed by US applicants at the EPO.
There is not a clear preference among the European applicants file more to the EPO, as applicants
in some countries seem to file more through other patent authorities (e.g. most of the patent families
from Germany or the Netherlands have a US patent application, while other countries like the United
Kingdom seem to prefer the PCT route). One explanation for this is that filing as a PCT provides
applicants with more time to evaluate their invention and develop their patent before applying for a
patent to be granted308. For example, 85% of patents have been filed as PCT by UK applicants in
the 1993-2011 period for ICT nanotechnology inventions. This compares with UK applicants filing
79% at the USPTO and 60% at the EPO.
308
In most cases, there are 30 months from the filing date of the initial patent application before an applicant
has to begin national phase procedures with individual patent offices.
http://www.wipo.int/pct/en/faqs/faqs.html
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Looking at the non-EU/EFTA and non-US countries of applicants, the filing patterns are quite
homogeneous with a clear preference to filing most at the USPTO, like Japan and Korea, the most
active countries in patent applications.
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GRANTED PATENTS
Applicants from the same EU and EFTA countries perform strongly in patents granted, namely those
from Germany, France, the Netherlands and the United Kingdom.
Table 7-6: Country of applicant and number of patents granted at EPO and USPTO
2 France 51 90
3 Netherlands 37 108
4 United Kingdom 23 46
5 Italy 8 19
6 Belgium 6 23
7 Switzerland 4 13
8 Sweden 3 13
9 Austria 2 4
10 Norway 2 3
11 Spain 1 7
12 Denmark 1 2
13 Portugal 1 2
14 Finland 0 10
15 Ireland 0 4
These four main countries in terms of granted patents have more patents granted by the USPTO
than by the EPO (see red bars in figure below). In some cases, like in Germany, the Netherlands or
the UK the number of granted patents by the USPTO is twice as large as the number of patents
granted by the EPO.
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granted to applicants for EU and EFTA countries, as shown in the tables below.
Table 7-7: Comparison of patent filings and patents granted by country of applicant (1993-
2011)
1 DE 330 1 DE 216
2 NL 197 2 NL 145
3 UK 181 3 FR 141
4 FR 175 4 UK 69
5 BE 47 5 BE 29
6 CH 46 6 IT 27
7 SE 42 7 CH 17
8 IT 40 8 SE 16
9 ES 28 9 FI 10
10 FI 26 10 ES 8
A very approximate estimate can be made of relative success in patenting between countries of
applicants by comparing the number of patent families and the number of patents granted 309. This
shows a high success rate for France and the Netherlands (followed by Italy, Germany and Belgium
and Austria with 60% or more).
Table 7-8: Estimate of relative patenting success by country of applicant
2 Netherlands 73.6
3 Italy 67.5
4 Germany 65.5
5 Belgium 61.7
6 Austria 60.0
7 Finland 38.5
8 United Kingdom 38.1
9 Sweden 38.1
10 Switzerland 37.0
When considering the country of applicant and the country of inventor as seen in patent family data,
it is clear that inventions are most often patented in the country in which they are invented (see
table below). However, it is not uncommon to have inventions that are patented outside of the
country in which they originate.
309
It should be noted that the data do not apply to the same filings as the patents applied for in 1993-2011 will
not be the same as the patents granted in 1993-2011, albeit that some overlap can be expected.
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Table 7-9: Country of applicant and country of inventor table for cross-comparison
INVT CA CH CN DE ES FR JP NL KR RU TW UK US
APPL
CA 92 9 9 5 26
CN 1 81 1 4 19
DE 293 15 11 15 60
FR 6 8 168 5 21
JP 5 6 1752 19 54
NL 14 9 25 91 12 76
KR 8 5 415 6 25
TW 15 1 98 19
UK 8 6 5 139 56
US 35 51 82 32 2068
310
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, the French Alternative Energies and Atomic
Energy Commission, FR www.cea.fr
311
Electronics and Telecommunications Research Institute, Korea
312
Centre National de la Recherche Scientifique, FR
313
Massachusetts Institute for Technology, US
314
Interuniversitair Microelectronica Centrum, BE
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Looking at the top 25 performing universities and PROs for patent families, 15 out of 25 are from
outside the US, 6 being from the EU28 or EFTA (from France, Belgium, Germany, Spain and the
United Kingdom). The tables show the top ten universities and PROs by number of patent families,
followed by the top non-US universities and PROs (based on top 25 universities and PROs).
The table below shows the top 18 performing universities and PROs for patent families in EU28/EFTA
countries. French organisations perform strongly (the two top organisations), as do organisations in
Germany and the UK.
Table 7-11: Number of patent families in the top 20 EU28/EFTA universities and PROs (1993-
2011)
GRANTED PATENTS
Of the top 15 universities and research organisations, four are from the EU28/EFTA countries (as
shown in the first of the two tables below which is ranked by the highest number of EPO patents
granted between 1993 and 2011). Seven of the organisations are from the US.
Ranking by the number of USPTO patents granted between 1993 and 2011, six of the top 15
universities and research organisations are in the US with just three in the EU28/EFTA (CEA, IMEC
and CNRS). See second table below.
315
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, the French Alternative Energies and Atomic
Energy Commission www.cea.fr
316
Centre National de la Recherche Scientifique
317
Interuniversitair Microelectronica Centrum
318
Consejo Superior de Investigaciones Cientificas, the Spanish National Research Council www.csic.es
319
Teknologian Tutkimuskeskus, Technical Research Centre of Finland www.vtt.fi
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Table 7-12: Universities / research organisations granted patents, by EPO patent numbers
320
Centre National de la Recherche Scientifique
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Table 7-15: Number of patent families for top ten non-US companies (1993-2011)
GRANTED PATENTS
The top ten companies that have been granted patents by the EPO and/or USPTO are shown in the
tables below321. The first table shows the top ten when the figures are sorted to obtain the highest
number of EPO patents and the second shows the top ten when they are sorted for USPTO patents.
321
This data does not take account of there being multiple offices of one company. Where the name differs in
the database, the companies are taken as being different.
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Companies from the US and South Korea are among the organisations with highest number of
patents granted by the EPO. Infineon Technologies (Germany) and Philips (the Netherlands) are the
fourth and fifth companies. Another Dutch company (NXP) is also in the table, with a significant
number of EPO patents granted.
Table 7-16: Number of patent families for top ten non-US companies (1993-2011)
Country Company EP US
US IBM 23 139
US Hewlett Packard Co 20 84
KR Samsung 18 106
DE Infineon Technologies 17 57
NL Philips 15 9
JP Fujitsu Ltd 11 72
NL NXP BV 10 9
JP Seiko Instruments 9 7
JP Toshiba 8 194
Table 7-17: USPTO and EPO granted patents by company (sorted by US patents)
Country Company US EP
JP Toshiba 194 8
US IBM 139 23
JP TDK Corp 126 8
KR Samsung 106 18
JP Hitachi 97 8
JP Sony 94 7
US Hewlett Packard 84 20
JP Fujitsu 72 11
NL Hitachi Global Storage Technologies 68 8
BV
US Seagate 66 2
Interestingly, five of the top 10 the companies with the highest number of patents granted by the
USPTO are Japanese while three are from the US. The Netherlands is the only EU28 country
represented in the table (Hitachi Global Storage Technologies BV).
The next two sections look at the ICT industry and ICT nanotechnology products and global markets.
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322
Turnover is defined in these statistics as market sales of goods or services supplied to third parties (Source:
Eurostat).
323
Production value measures the amount actually produced by the unit, based on sales, including changes in
stocks and the resale of goods and services (Source: Eurostat).
324
Value added is the gross income from operating activities after adjusting for operating subsidies and indirect
taxes. Value adjustments (such as depreciation) are not subtracted (Source: Eurostat).
325
OECD Information Economy–Sector definitions based on the International Standard Industry
Classification (ISIC 4) available at http://www.oecd.org/science/scienceandtechnologypolicy/38217340.pdf ),
Annex 1, pg. 15.
326
EUROSTAT (2015) Annual detailed enterprise statistics for industry (NACE Rev. 2, B-E)
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assessment of the European ICT sector by the Joint Research Centre - Institute for Prospective
Technological Studies (JCR-IPTS) in the PREDICT 2015 report327.
Overall, the whole ICT sector value-added amounted to EUR 516.5 billion in 2012, representing a
share of 3.99% of EU GDP. ICT services contributed by far the largest share of ICT sector value
added (92.27% in 2012), accounting for 3.68% of EU GDP, but the ICT manufacturing value added
contributed only 7.73% of ICT sector value added totalling 0.31% of GDP. Since 2006, the share of
ICT manufacturing value added has dropped significantly from 12.18% in 2006 to 7.73% in 2012.
Table 8-2: Turnover, production value and value added of ICT manufacturing enterprises
Source: Eurostat, Annual detailed enterprise statistics for industry (NACE Rev. 2, B-E)
The value-added of ICT manufacturing decreased significantly in the period 2008 – 2012 (annual
growth rates between -6% and -23 %), with only a small recovery in 2010. This shows that ICT
manufacturing has suffered more from the downturn of economic activity than ICT services, and it
continued to decrease in 2012 after a short revival in 2010.
Within the ICT manufacturing, as defined above, the manufacturing of electronic components and
boards has the largest share with a value added share of 0.13% of GDP in 2012.
327
Matilde Mas and Juan Fernández de Guevara Radoselovics (2015) THE 2015 PREDICT REPORT. An Analysis
of ICT R&D in the EU and Beyond, EUR 27510 EN – Joint Research Centre – Institute for Prospective
Technological Studies
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According to the PREDICT 2015 report, Germany (24.98%) dominated ICT manufacturing (full sub-
set), followed by Italy (15.80%), the UK (13.28%), Sweden (9.00%) and France (7.09%). The
thirteen new Member States contributed more to ICT sector value added in ICT manufacturing
(12.23%) than in ICT services (7.36%), probably because of the offshoring of activities towards
these new Member States.
For the three ICT manufacturing subsectors discussed in this report, the highest value added came
from Germany (25%), France (15%), United Kingdom (12%), Italy (11%) and Ireland (9%) in 2012.
Ireland was the most specialised Member State with both manufacturing of electronic components
and boards and manufacturing of computers and peripheral equipment, contributing 1.5% of the
Irish non-financial business economy value-added in 2010. The Czech Republic is the most
specialised Member State in the manufacturing of magnetic and optical media. Germany employed
the largest number of people with over 99,500, followed by France (52,200), Italy (45,000) and the
United Kingdom (37,600). Hungary, Poland, Romania and the Czech Republic also have a relatively
large share in employment (3% to 6%).
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highest R&D intensity (24%, BERD/value added) in the total ICT sector.
According to Eurostat328, the German ICT manufacturing industry (three subsectors) had the largest
EU business R&D expenditures (EUR 2.14 billion), followed by France (EUR 968 million) and Italy
(EUR 589 million).
According to the PREDICT 2015 report, in 2012, 10% of employees in the EU ICT manufacturing
were R&D personnel. Manufacture of computers (9.59%) and Manufacture of electronic components
(8.59%) belong to the ICT subsectors that have the highest R&D intensity.
328
EUROSTAT (2015) Business enterprise R&D expenditure (BERD) by economic activity (NACE Rev. 2)
329
http://ec.europa.eu/eurostat/web/science-technology-innovation/data/database
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Moreover, in terms of value generated from the whole supply chain (including design, equipment,
and material as well as from fab-less and virtual components activities), Europe's share of value
produced in 2012 is between 10 and 11% of the world market (see also figure below).
Oxford Economics330 calculated the value added of European semiconductor industry at USD 24.2
billion, but when including the indirect (in the value chain) and induced impact (on other industries)
the value added is estimated at USD 77 billion in 2012. The figure below puts the European position
in a global perspective. Europe has a share of 13.8% in the global value added directly generated
by the semiconductor industry.
Oxford Economics (2014) Enabling the Hyperconnected Age: The role of semiconductors, prepared for the
Global Semiconductor Alliance
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94
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Source: European Industrial Strategic Roadmap for Micro- and Nano-Electronic Components and Systems
(2014), the Electronic Leaders Group: based on Gartner, Yole, SEMI.
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Figure 8-5: Share of production for the top 10 EU-28 countries in Micro- and
Nanoelectronics (%)
Germany has also the largest European share in turnover in micro- and Nano electronics (50% in
2013) (turnover at headquarters level). France follows with 20% with the Netherlands in the third
position with 17.5%. See also the figure below.
Figure 8-6: Share of turnover for the top 10 EU-28 countries in Micro- and Nanoelectronics
(%)
In its second report (December 2015), the KETs Observatory focused on the extent to which the EU
is using the potential of KETs to manufacture KETs-based products and applying KETs in production
processes, covering a large part of the value chain. Following this approach, micro- and nano-
electronics enabled an EU production volume of EUR 306 billion in 2013. Germany, France, the UK
331
Including the 10 EU-28 countries with the highest share of production in the respective KET with respect to
the production of all 28 countries. Original source: PRODCOM database – IDEA Consult calculation
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and Italy hold the top positions in terms of share of production. Spain and Poland also show
considerable activity in this area.
Figure 8-7: Share of KETs-enabled production for the TOP 10 EU-28 countries in Micro-
and Nanoelectronics (%)
Estimates of the European workforce employed by the semiconductor industry differ substantially,
depending on which part of the value chain is included. Oxford Economics estimates the
semiconductor workforce at 105,000 employees, which is similar to the workforce in Japan and
Korea, but half the workforce in China or the US. The figure below shows the global distribution of
the semiconductor workforce in 2012, according to Oxford Economics (2014).
332
Original source: PRODCOM database and Eurostat – TNO calculation
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Figure 8-9: Absolute KETs-enabled employment for the TOP 10 EU28 countries in in Micro-
and Nano-electronics
333
E.g.: European Industrial Strategic Roadmap for Micro- and Nano-Electronic Components and Systems
(2014), the Electronic Leaders Group; Communication from the Commission to the European
Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions
(2013) A European Strategy for Micro- and Nano-electronic Components and Systems; Aeneas & Catrene
(2012) Innovation for the future of Europe: Nano-electronics beyond 2020; http://europa.eu/rapid/press-
release_MEMO-13-451_en.htm ;
334
Direct employment linked to manufacturing of KETs based products and Indirect employment linked to
research activities performed in companies and technical services. Upstream R&D jobs of service providers
or public R&D institutes are excluded.
335
Original source: PRODCOM database and Eurostat –Fraunhofer ISI calculations
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Figure 8-10: Share in KETs-enabled employment, top ten EU28 countries in micro- and
nano-electronics
The next section reports on products, markets and companies for nanotechnology and ICT.
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9.2 Global markets and forecasts for ICT products using nanotechnology
Global sales for nanotechnology products in the ICT sector were estimated to be USD 2 billion in
2013 and are forecast to be USD 10.2 billion in 2019. The figure below shows the forecast growth
in commercialised products (USD 9.9 billion in 2019) and the expected growth in emerging products
(USD 373 million in 2019). It is seen that much of the growth is expected to be driven by products
that have already been commercialised.
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The market data presented there is based mainly on reports by BCC Research342. A comparison of
global sales estimates for ICT by type of nanomaterial shows that thin films accounted for the largest
share in 2013, with further increases expected to 2019. The main driver of this trend is the expected
growth in the market for low-k dielectric coatings.
Figure 9-2: Global sales estimates for nanotechnology and ICT by material type, 2013 and
2019
The market share of solid nanoparticles is expected to decrease by 2019 to about half of its size in
2013, while the share of the sales of thin films is projected to almost triple in the same timeframe.
336
ZVEI-Fachverband “Electronic Components and Systems; Mikroelektronik-Trendanalyse bis 2017”; April
2013 http://www.zvei.org/Verband/Pub likationen/Seiten/Mikroelektronik-Trendanalyse-bis-2017.aspx
337
VDI TZ 2013: Unternehmensbefragung nano. DE-Report 2013, June 2013
338
This breaks down into approximately one third of the total monetary value each for (i) 22nm; (ii) 32/28 nm;
and 45/40 nm.
339
BCC 2012: “Global Markets and Technologies for Compound Semiconductors”, press release, 12 September
2012 http://www.bccresearch.com/pressroom/smc/global-compound-semiconductor-component-sales-
reach-$47.4-billion-2017
340
BCC 2013: “BCC Research Projects the Flexible Devices Manufactured by Roll-to-Roll Technologies to Reach
Nearly $22.7 Billion by 2017”, Market report abstract https://bccresearch.wordpress.com/2013/05/23/roll-
to-roll-technologies/
341
IDTechEx 2012: “Conductive Ink Markets 20152025: Forecasts, Technologies, Players”, Market report
abstract http://www.giiresearch.com/report/ix235628-conductive-inks-markets-2012-2018.html
342
It should be noted that market estimates and forecasts undertaken by different organisations are based on
different assumptions and methodologies, sample a different set of expert opinions and use different models to
arrive at the data they present. By using data from one organisation, and linking it to original NanoData work
on products, the aim is to minimise the error between datasets. However, there is no evidence that these data
are more correct than other data. In order to address this, future work of the NanoData project will involve
stakeholder interviews and workshops having the goal of evaluating the data, working towards its validation.
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Carbon nanotubes are currently forecast to play only a marginal role in terms of shares of sales.
9.3.1 Overview
To date, 84 ICT-related products using nanotechnology have been identified as being commercially
available on the market. The figure shows a rough breakdown of the types of products, albeit that
some categories overlap and a decision has been taken as to which category to put them in. The
main message is that nanotechnology occurs most in components but also strongly in materials.
Components (53%) account for the biggest share of these commercialised products. Materials to
make and to improve ICT show almost equal shares (17% and 18%), while products for data storage
represent 8% of the products. Noteworthy are products in the subsector novel methods (4%), these
are quantum computers and spintronics-based sensors.
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EXISTING APPLICATIONS
A HARD DISC MEDIA AND HEADS
Digital information can be stored in different types of device depending on the use and how
frequently the required access. For example, data to be stored for a long time with infrequent access
are normally stored in hard disc drives. These are magnetic devices with high data density —
nowadays on the order of terabytes — in which information is encoded in the direction of
magnetisation of small areas of a magnetic medium. Each of these magnetic 'bits' stores a logic '0'
or '1', and is written or read by a recording head that traverses the disc at a distance of a few
nanometres. The information stored in hard disc drives is non-volatile as it persists after power to
the device has been cut off. The speed of access to the data is relatively slow (milliseconds) because
the read/write procedures are mechanical343.
Hard disc drives using magnetic recording are likely among the most complex devices using
nanotechnology. Today’s commercial hard disc drives can store information at > 600 Gbit/in 2, with
data bits < 60nm x 15nm, read sensor dimensions < 50nm x 30nm, and the recording head “flying”
a few nanometres (nm) above the nanostructured recording disc. To maintain this technological
evolution, every facet of the magnetic recording system must be continuously reduced in dimensions
while maintaining adequate signal-to-noise ratio for writing and reading information344. Each disc
surface is made from a complex structure of thin metal films. These layers work together to store
magnetic data which can be written with and read by a recording head. Technological advances have
enabled the amount of data that can be stored per square centimetre to double each year for the
last decade. The ‘read head’ of a current hard disc drives uses the effect of giant magneto-resistivity
(GMR) to sense the magnetic data. GMR sensors use metallic strips, less than 2nm thick, which are
extremely sensitive to changes in magnetic fields. These are connected electrically to the disc drive
electronics345.
In 2013, Western Digital announced a nanotechnology breakthrough that will allow the company to
double data storage capacity on hard disc drives (HDD). The discovery was made by HGST Labs, a
company owned by Western Digital (WD), using nanolithography to imprint patterns on the thin film
of hard drive platters where data is to be stored. The discovery allows for twice the bit density of
today's disc drives346.
MARKET DATA AND FORECASTS 347
The total materials cost of the sputtered magnetic coatings used on hard discs is estimated at USD
416 million in 2013 and USD 429 million in 2014. It is forecast to grow at a compound annual growth
rate (CAGR) of 6.4% to USD 585 million in 2019.
343
Nature Nanotechnology Editorial: Memory with a spin, Nature Nanotechnology 10, (2015): 185
344
http://www.mse.engin.umich.edu/about/events/nanotechnology-and-future-of-the-hard-disk-drive
345
https://www.conted.ox.ac.uk/courses/professional/nanobasics/nano/accessWeb/technology.html
346
COMPUTERWORLD: Western Digital claims HDD capacity doubled with nanotech breakthrough, March 1,
2013
347
BCC Research (2014), Nanotechnology: A Realistic Market Assessment
348
http://www.wdc.com/
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Figure 9-4: Global market for sputtered magnetic coatings used on hard discs to 2019
Magnetic recording tapes used for video, audio and digital data storage consist of a magnetic coating
deposited onto a non-magnetic support by either a particulate coating process or vapour deposition
(evaporation). Traditionally, the magnetic particles used to form magnetic recording layers have
been gamma-iron oxide (γ-Fe2O3 or maghemite), cobalt-modified gamma-iron oxide (Co-γ-Fe2O3)
or cobalt-modified magnetite (Co-Fe3O4). Generally speaking, the more demanding the storage
requirements, the smaller the particle size required. Particles of γ-Fe2O3 or Co-γ-Fe2O3 about 200
nm to 400 nm in length and 25 nm to 50 nm in width are commonly used to form magnetic coatings
on audio and video recording tapes, which do not require extremely high recording densities. High-
density storage applications tend to use metallic iron or iron-cobalt particles of less than 100 nm in
length in order to increase the signal-to-noise ratio and the film smoothness349. In addition to
magnetic iron/iron oxide nanoparticles, the magnetic layer of recording tape typically includes
alumina nanoparticles as an additive to reduce tape wear350. Some of the company activities in this
include:
• In 2001, Fuji Film introduced its NANO CUBIC technology, an ultra-thin layer coating that
results in higher resolution for recording digital data, ultra-low noise and high signal to-noise
ratios that are ideal for magneto resistive (MR) heads. Two types of magnetic particles were
developed for NANO CUBIC technology, both tens of nanometers in size: acicular
ferromagnetic alloy particle and tabular ferromagnetic hexagonal barium ferrite particle351.
• Also in 2014, Sony Corporation announced that, by independently developing a soft magnetic
underlayer with a smooth interface using sputter deposition, it had succeeded in creating a
nano-grained magnetic layer with fine magnetic particles and uniform crystalline orientation.
This enabled Sony to achieve the highest areal recording density for tape storage media of 148
Gb/in2 (gigabits per square inch). This areal recording density is equivalent to approximately
74 times the capacity of current mainstream coated magnetic tape storage media, and makes
it possible to record more than 185 TB (terabytes) of data per data cartridge352.
349
Also because metallic particles exhibit higher coercivities, i.e. the intensity of the applied magnetic field
required to reduce the magnetisation of a ferromagnetic material to zero from its magnetic saturation
state.
350
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.63
351
FUJI Film: Product Information
352
http://www.sony.net/SonyInfo/News/Press/201404/14-044E/
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Magnetic recording media consume significant but declining amounts of alumina and iron oxide thin
film materials, as shown in the figure below.
Figure 9-5: Global market for oxide thin film materials used in magnetic tapes
353
http://www.fujifilmusa.com/gateway/recording_media/
354
http://www.fujifilm.eu/eu/products/recording-media/
355
https://www.fujifilmholdings.com/en/investors/annual_reports/2015/pack/pdf/Annual-Report-2015.pdf
(USD figures at an exchange rate of 120 yen to the USD)
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The most common types of optical recording media (i.e. audio CD and video DVD) generally have a
50-nm thick reflective aluminium film layer that is sputtered onto a polycarbonate substrate and
spin-coated with a protective lacquer coating. The newer blu-ray discs (BD) contain a similar
reflective layer356.
MARKET DATA AND FORECASTS 357
In 2013, global consumption of nanostructured aluminium film materials in the production of optical
recording media (e.g., CD and DVDs) was about 52 metric tons, with a value of USD 1.7 million. In
the near to mid-term, consumption of nanostructured aluminium film materials for CDs and DVDs
will be driven by projected trends in unit disc sales. Data on total global shipments of optical
recording media (e.g., CDs, DVDs and Blu-Ray discs) are hard to obtain, but are projected to trend
downwards as alternative content delivery and storage technologies gain market share. The figures
in the table below assume that shipments of optical storage media are decreasing at a CAGR of -
3.8%, with a proportional reduction in consumption of nanostructured aluminium thin film materials.
Figure 9-6: Global market for thin film materials in optical recording media
EMERGING APPLICATIONS
A COMPUTER MEMORY
In the information storage industry, there is now an effort to develop new concepts for memory
devices that combine two key aspects: cheap, non-volatile, high-density information storage (as in
hard disc drives) and robust, fast access (as in random access memory (RAM)). Flash memory is an
example, as it is a solid-state yet non-volatile memory, and is currently used in mobile applications.
However, Flash is slow and has low endurance. Some development activities in the area of new
solid-state technologies358 are as follows:
• Non-volatile random-access memory (NRAM) is a carbon nanotube-based technology developed
by Nantero Inc. (Woburn, MA, USA). The memory is reported to be hundreds of times faster
than current memory for mobile devices359. In the production of NRAM, a film of carbon
nanotubes (CNTs) is deposited onto a silicon substrate that contains an underlying cell select
356
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.63
357
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.153
358
Nature Nanotechnology Editorial: Memory with a spin, Nature Nanotechnology 10, (2015): 185
359
PCWorld: Nantero's radical carbon-nanotube memory could replace SSDs and DRAM, Jun 2, 2015
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device and array lines (typically transistors or diodes) that interface the NRAM switch 360.
Advantages of NRAM are that it operates at the speed of DRAM (dynamic RAM) and is nonvolatile,
meaning it can store data when the power is switched off. The small size of carbon nanotubes
allows more data to be stored in smaller volumes, and the storage chips will consume
significantly less power than flash storage and DRAM. Using this technology, it should be possible
to increase the amount of storage and increase the battery life of laptops and mobile devices.
• Carbon-nanotube chips are just one of a number of new memory types with the potential to
replace DRAM and NAND flash. As devices get smaller, it is becoming difficult to add more
storage capacity while reducing the size of NAND flash chips. Possible DRAM and NAND flash
replacements like RRAM (resistive RAM) and MRAM (magnetoresistive RAM) are already being
used on a limited basis, and phase-change memory (PCM) — backed by IBM and Samsung — is
still being refined361.
• In 2011, scientists at Purdue University developed a computer memory using nanotechnology
that could be faster than current technology and use far less power than flash memory devices.
The new technology is called FeTRAM, for ferroelectric transistor random access memory. It
combines silicon nanowires with a "ferroelectric" polymer, a material that switches polarity when
electric fields are applied. The FeTRAM is nonvolatile storage, meaning information stays in
memory when the computer is powered down362.
B HOLOGRAPHIC MEMORY
In holographic data storage a ‘data beam’ holding information is crossed with a ‘reference beam’ to
produce an interference pattern on a light-sensitive material, thereby storing the data. To download
the data, the reference beam is shone onto the material at a given point, and the original data beam
is reconstructed through the interaction of the reference beam and the material. The data is read by
a detector that converts the beam into electrical signals.
The most common recording materials for holographic storage are inorganic crystals and polymers.
While polymers are more sensitive and require less powerful lasers than inorganic crystals, they
have a greater tendency to deform, thereby corrupting the data363.
Holographic memory can potentially store 1 terabyte364 (TB) of data in a crystal smaller than one
centimeter cubed. Data from more than 1,000 CDs could fit on a holographic memory system. Most
computer hard drives only hold 10 to 40 GB of data, a small fraction of what a holographic memory
system might hold365. Developments in the area include:
• In 2014, a collaboration between researchers from the University of California, Riverside Bourns
College of Engineering and the Russian Academy of Science demonstrated a holographic memory
device using spin waves – a collective oscillation of spins in magnetic materials – instead of the
optical beams. Spin waves devices have the advantage of being compatible with the conventional
electronic devices and could operate at a much shorter wavelength than optical devices, enabling
the production of smaller electronic devices with greater storage capacity. The research
combines the advantages of the magnetic data storage with wave-based information transfer366.
• Several promising technologies have been developed by companies such as InPhase
Technologies, Colossal Storage and GE Global Research. The Colossal Storage system is
apparently the only one that uses nanophotonic technology, in which light interacts with
nanoscale structures. In other holographic technologies, the light interacts with the storage
medium on a macroscale (> 100 nm) level. The Colossal Storage technology uses a UV laser to
write data spots as small as 30 nm in a ferroelectric perovskite thin film367.
By 2019, sales of nano-devices currently under development, primarily nanostructured holographic
360
http://nantero.com/technology/
361
Ibid
362
UPI Science News: New computer memory uses nanotechnology, Sept. 27, 2011
363
MIT Technology Review: Holographic Memory, September 1, 2005
364
A terabyte of data equals 1,000 gigabytes, 1 million megabytes or 1 trillion bytes.
365
How Stuff Works Tech: How Holographic Memory Will Work,
366
University of California, Riverside, UCR Today: Using Holograms to Improve Electronic Devices, February 19,
2014
367
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.104
107
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368
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.195
369
http://nantero.com/technology/
370
PCWorld: Nantero's radical carbon-nanotube memory could replace SSDs and DRAM, Jun 2, 2015
108
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been invested in R&D, exact figure was not revealed but the company main focus was to drive
the investment from government organisations to support R&D. Some of Nantero’s strategic
investors include Charles River Ventures, Globespan Capital Partners, Harris and Harris Group,
and Draper Fisher Jurvetson. Nantero is expected to experience a significant growth
opportunity in the future. With many deals still underway, Nantero’s strategy of targeting the
commercial electronics market is expected to pay rich dividends.
Licensing is the key revenue strategy at Nantero. The company is planning to license its
intellectual property of unique NRAM design using CNT technology to foundries, chip
manufacturers and electronic companies around the world. Nantero targets embedded and
standalone markets with an IP (Intellectual Property) licensing business model. It has a robust
patent portfolio of about 175+ granted US patents and more than 200 pending patent
applications. The company’s technology has been leveraged in 2 of the top 5 foundries in the
world. This will help Nantero to finance itself through recurring income, making it capital
efficient in the long term. Nantero is also leveraging the strategic partnership model to
commercialise its CNT NRAM technology. The company has engaged in long-term partnerships
with major tier participants including Lockheed Martin, Schlumberger, ON Semiconductor, and
Novati Technologies.
371
Aijazi A T (2014), Printing Functional Electronic Circuits and Components, Dissertation at Western Michigan
University
372
Kamyshny A, et al. (2011), Metal-based Inkjet Inks for Printed Electronics, The Open Applied Physics
Journal, 2011, 4: 20
373
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.37
374
Business Wire, October 21 2015
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alternative to the use of silver for conductive inks in printed electronics. The dispersed copper
concentrate (for ink manufacture) can be used as a raw material for conductive inks that can be
printed using a variety of techniques. The “pre-ink”, which can be thought of as a conductive
“pigment” for ink formulators, remains stable as non-oxidised copper metal for a period of
several months and contains only copper and an antioxidant. By using copper particles, the ink
requires a lower sintering temperature than silver making it possible to deposit conducting tracks
onto less substrates such as flexible polymer-based materials that do not have high thermal
stable. In addition, conductivity has been achieved when sintering the deposited material in air,
without the need for inert atmospheres375.
• DuPont Innovalight makes silicon inks and licenses proprietary technology for solar cells to
manufacturers. The silicon nanoparticles are suspended in a chemical mix. When applied to
silicon solar cells during the manufacturing process, the ink boosts the cells' absorption of
sunlight at lower wavelengths, generating more electricity376. The proprietary material is
comprised of silicon nano-particles formulated into a screen printable ink. The material is
compatible with low-cost, industry standard screen printers normally used in the printing of
metal contacts377.
Available estimates and forecasts concentrate on silver conductive nano-ink. The market for all types
of conductive silver ink was worth USD 1.4 billion in 2013 and USD 1.5 billion in 2014, and is
expected to grow to USD 2 billion by 2019.
375
http://www.prometheanparticles.co.uk/copper-ink-for-printed-electronics/
376
DuPont (2012): “DuPont Microcircuit Materials Introduces Highest Efficiency Solamet® Photovoltaic
Metallisation Pastes to Date.”
377
http://www.dupont.com/products-and-services/solar-photovoltaic-materials/silicon-inks.html/
378
www.basf.com
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Figure 9-7: Global market for silver nanoparticles in electronic printing to 2019
Conductive inks made with silver nanoparticles are a new technology, and they accounted for a
relatively small share (approximately 15%) of the market for conductive silver inks in 2013 to 2014.
However, by 2019, the nanotechnology share of the conductive silver ink market is expected to
increase to at least 50% of the total. If materials account for about 50% of the final value of the
inks and silver nanoparticles represent about half of the total material cost on average379, the market
for silver nanoparticles for these inks can be estimated at one quarter of the total for conductive
silver inks (i.e. USD 250 million for silver nanoparticles of USD 1 billion for nanotechnology silver
inks in 2019).380
379
The percentage can vary considerably, according to the unit price of silver
380
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.133
381
http://www.nano-di.com/about-nano-dimensions
111
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EMERGING APPLICATIONS
GRAPHENE PRINTED ELECTRONICS
Conductive inks rely for their conductivity on the inclusion of silver, carbon, graphite, or other
precious metal-coated base materials. Common conductive inks can be classified into three
categories: noble metals, conductive polymers, and carbon nanomaterials. A selection of conductive
inks is offered on the market, to meet the demands of many applications: electronics, sensors,
antennae, touch screens, printed heaters and more. Due to its high charge carrier mobility,
superlative thermal and chemical stability and intrinsic flexibility, graphene has been demonstrated
for a number of applications in printed electronics including chemical and thermal sensors and
supercapacitors. While graphene inks open up potential applications such as printed electronics and
packaging, they often need to be specially formulated or adjusted for specific uses, requiring unique
substrates or processing/printing methods (rotogravure, flexo, or screen printing processes etc.)382.
Some ongoing activities in the area include:
• In 2012, Vorbeck Materials (Jessup, MD, USA) partnering with MeadWestvaco Corp. a global
packaging company has brought the first commercially available graphene product to market.
The product is an anti-theft retail package product called Siren™, which is part of MWV’s
Natralock™ product packaging line. The packaging design prevents theft or tampering by setting
off an alarm on an individual package if it is torn open or upon attempted theft. Vorbek’s Vor-
ink™ provides the package with a sensor that can detect when the package has been moved,
taken out of the building or cut open383.
• In 2015, researchers at the University of Cambridge in collaboration with Cambridge-based
technology company Novalia, developed a low-cost, high-speed method for printing graphene
inks using a conventional roll-to-roll printing process. The method would allow graphene and
other electrically conducting materials to be added to conventional water-based inks and printed
382
http://www.graphene-info.com/graphene-inks
383
Nanlyze: Vorbeck’s Commercially Available Graphene Products, April 1, 2014
112
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using typical commercial equipment at the high speed associated with printing presses for
newspapers. Silver-based inks in current use cost GBP 1000 or more per kilogramme. This new
graphene ink formulation would be 25 times cheaper. In addition, graphene and other carbon
materials are recyclable, unlike silver. Once dry, the ‘electric ink’ is also waterproof and adheres
to its substrate extremely well. In the short to medium term, the researchers hope to use their
method to make printed, disposable biosensors, energy harvesters and RFID tags384.
Vorbeck Materials is currently the sole commercial producer of graphene-based inks. While it does
not publish sales data, it is estimated that its sales of graphene inks were significantly less than USD
1 million in 2013 and 2014. By analogy with other nanotechnology-based inks, it has been estimated
that sales of graphene inks could exceed USD 12 million by 2019. If the component of the inks is
the same as for silver nanoparticles as outlined previously, their overall market value would be USD
3.5 million by 2019.
384
http://www.aipia.info/news-Low-Cost-High-Speed-Graphene-Inks-for-Printed-Electronics-486.php
385
BCC (2014), Nanotechnology: A Realistic Market Assessment p.139
386
Sivanandini M (2013), Chemical Mechanical Polishing by colloidal silicon slurry, International Journal of
Engineering Research and Applications, Vol. 3, Issue 3, May-Jun 2013: 1337
387
BCC Research, (2014), Nanotechnology: A Realistic Market Assessment, p.26
388
http://www.baikowski.com/
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Global consumption of silica and alumina nanoparticles used in CMP compounds was estimated to
be about 36,400 metric tons, with a value of USD 556 million, in 2013. Of this, silica accounted for
about 87%. CMP nanoparticle consumption was estimated to be USD 596.4 million in 2014 and is
forecast to grow to USD 938.9 million by 2019, for a CAGR of 9.5% from 2014 through 2019. 389
389
BCC Research, (2014), Nanotechnology: A Realistic Market Assessment, p.116
390
Zhang Y, et al. (2008), Carbon nanotube plastic-packaging material for class 0 device ESD protection -Real
life electrical performance comparison for carbon-filled plastics, Electrical Overstress/Electrostatic
Discharge Symposium, 2008
391
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.85
392
Arkema: Graphistrength® thermoplastic masterbatches, product information
393
http://www.trekinc.com/
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Trek designs and manufactures high-voltage amplifiers, piezo drivers, power supplies &
generators and high performance electrostatic measurement instruments (including
electrostatic sensors and detectors, electrostatic discharge (ESD) instruments, electrostatic
voltmeters, charged plate monitors, and surface resistance/resistivity meter).
Trek Japan KK was founded in 1987 in Tokyo, Japan, for the purpose of providing Japanese
and other Pacific Rim local application engineering support, sales, and service. The Trek
Holding Company Ltd., Japan, announced the acquisition in 2006 of U.S. based Trek Inc. and
Trek Japan KK. This acquisition was part of the overall Succession Plan of the Trek Group
and allows for both Trek Inc. and Trek Japan KK to maintain its current operations and
management structures.
In 2013, global consumption of polycarbonate/carbon nanotube compounds, most of which are used
to make ESD electronics products and clean room equipment, was USD 11.9 million. Global
consumption of all types of filled electrostatic control products is projected to grow in volume at a
CAGR of 7.3% through 2019, a rate of increase expected to apply to polycarbonate/carbon nanotube
composites electrostatic control products as well. However, after factoring in a projected decline in
the average cost of polycarbonate/carbon nanotube composites through 2019 as a result of
improvements in production technologies and increased scale of production, the value of the market
is projected to increase at a CAGR of only 2.6%, reaching USD 14 million by 2019, as shown below.
394
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, pp.177-178
395
McGahay V (2010), Porous Dielectrics in Microelectronic Wiring Applications, Materials 2010, 3: 536
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Nanoporous polymer thin films such as Dow Chemical’s SiLK are used in leading-edge computer
chips because of their low dielectric constant, but they are competing with a variety of other
materials, including inorganics and aerogels. While Dow is reportedly the leader in the low-k
dielectric market, its market dominance is by no means assured396. IBM Corp. decided to switch
from SiLK to the rival small molecule chemical vapor deposition (CVD) technique. Similarly, the
world's second largest foundry, Taiwan-based United Microelectronics Corp. (UMC), dropped SiLK in
favor of the small-molecule CVD Coral process from Novellus Systems Inc. (San Jose, Calif.) 397.
Market hurdles that SiLK must overcome are reported to include relatively high materials costs and
the need to incorporate additional steps in the semiconductor production process. In the longer term,
there is also the possibility of using aerogels as a semiconductor dielectric material398.
MARKET DATA AND FORECASTS
In 2013, global consumption of low-k nanofilm materials was about 16 metric tons with a value of
USD 575 million. Polymeric materials, notably Dow’s SiLK resins, dominate the market but their
market share is expected to decline amid growing materials for other low-k materials, especially
inorganics. The market for low-k dielectric materials is projected to grow rapidly as the
semiconductor industry increasingly moves into the nanometre range. Low-k dielectric applications
are also expected to expand outside leading-edge semiconductors into other applications such as
memory and logic devices. It is difficult to quantify directly the impact of these trends on future
consumption of low-k dielectrics. However, based on information provided by industry sources, a
plausible estimate of the total market for low-k dielectric films by 2019 is likely to be at least 275
tons, or about USD 6.9 billion399.
396
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.69
397
IEEE Spectrum: SiLK Slips - IBM follows industry trend, chucks spin-on chip insulator, 1 December 2003
398
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.69
399
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.
400
http://www.dow.com/
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The global market estimate for nanoscale electro-conductive coatings was USD 32 million in 2013,
and growing at a CAGR of 8.4% (between 2014 and 2019), to reach USD 51 million by 2019404.
401
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.66
402
Umicore Zinc Chemicals, product info on Zano® Al-10
403
http://www.umicore.com/
404
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.159
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405
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.87
406
http://hybridplastics.com/
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EMERGING MARKETS
GRAPHENE HEAT SPREADERS
Silicon-on-insulator (SOI) wafers and designs offer major advantages over traditional silicon device
structures such as improved electrical isolation, reduced parasitic capacitances, improved radiation
hardness and higher packing density. Traditional devices can also suffer from unwanted thermal
effects that can lead to performance degradation and premature thermal breakdowns. The smaller
components become and the higher the circuit speeds, the greater the problems associated with
heat generation, power densities and temperature rise. Efficient thermal management becomes an
integral part of the device design for long-term reliability and optimum performance. One possible
solution for removing heat from the localised hot spots is to incorporate chips with materials that
have very high thermal conductivity, i.e. high-heat flux (HHF) thermal management such as
graphene which exhibits extremely high intrinsic thermal conductivity408. Developments in this area
include:
• A North Carolina State University researcher in 2012 developed a technique that uses a heat
spreader made of a copper-graphene composite, which is attached to the electronic device using
an indium-graphene interface film, both of which have higher thermal conductivity, allowing the
device to cool efficiently. The copper-graphene film’s thermal conductivity allows it to cool
approximately 25% faster than pure copper, which is what most devices currently use 409.
• A research team led by scientists at Chalmers University of Technology in Sweden found in 2013
that multiple layers of graphene— a two-dimensional material comprised of carbon atoms
arranged in a hexagonal pattern—demonstrate strong heat conducting properties that could be
used to remove heat from inside electronic devices. In their study, the researchers focused on
altering the temperature in the most heat-intensive areas of an electronic device—such as inside
407
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.179
408
Subrina S, et al. (2009), Graphene Heat Spreaders for Thermal Management of Nanoelectronic Circuits,
University of California – Riverside (UCR), p.1
409
Electronics Cooling: Researcher Finds Cheaper Way To Cool Electronic Devices, April 20 2012
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9.3.2.8 Components
EXISTING APPLICATIONS
A MULTILAYER CERAMIC CAPACITORS
Multilayer ceramic capacitors, or MLCCs, are important building blocks in modern electronics and
make up approximately 30% of the total components in a typical hybrid circuit module. Multilayer
capacitors consist of a monolithic ceramic block with comb-like sintered electrodes. These electrodes
come to the surface at the face ends of the ceramic block where an electrical contact is made by
burnt-in metallic layers412.
Nanoscale barium titanate or strontium titanate powders are typically used to form the dielectric
ceramic layers and noble metals (e.g. platinum or silver-palladium) the internal electrode layers of
MLCCs. Given the rising costs of noble metal powders, substitutes are being sought, using base
metal powders such as nickel to form the internal electrodes. To produce the capacitor from the
powders, the dielectric powder is mixed with a binder and solvent to obtain slurry that is cast into a
rectangular ceramic green sheet. The conductive metal paste is then screen printed onto the sheet.
A stack of green sheets interspersed with conductive paste layers is formed and then fired to obtain
the multilayer ceramic capacitor413.
It has been estimated that global MLCC output was 1.7 trillion units in 2013, 5% of the units (i.e.,
85 billion units) being fabricated using nanoscale powders. Given that materials costs are estimated
to represent 28% of the selling price of an MLCC and, in 2013, the average MLCC selling price was
USD 0.01, the average materials cost is USD 0.0028 per MLCC. The total materials cost of the
estimated 85 billion MLCCs fabricated using nanoparticulate materials in 2013 was thus USD 238
million. It is estimated that 20% of that market is titanate-based (USD 143 million) and 60% is
nickel-based (USD 143 million) as shown in the figure below.
410
Electronics Cooling: Graphene Heat Spreader Reduces Hotspot Temperatures, July 8 2013
411
Ibid
412
Future Electronics: What is a ceramic capacitor
413
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.37
414
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.132
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Figure 9-13: Global sales for nanoparticles used in ceramic capacitors to 2019
Global consumption of MLCCs has increased at a CAGR of 12.9% since 2004. The projections in the
figure above assume that MLCC consumption continues to grow at a CAGR of 12.9%, reaching nearly
3.6 trillion units by 2019. The projections further assume that 10% (360 billion) of the MLCCs
produced in 2019 incorporate titanate and nickel nanoparticles.
415
Erokhin S, et al. (2011), Magnetic nanocomposites: new methodology for micromagnetic modeling and
SANS experiments, Cornell University,Working paper, p.1
416
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.85
417
http://www.magnetec.de/
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electronic metering and the full range of power electronics/EMI. Magnetec currently has around
400 employees and worldwide facilities (in Hungary since 1989 and in China since 2009). The
turnover of the company in 2013 was c. EUR 26 million. MAGNETEC supplies to companies
such as ABB, Siemens, GE and Schneider Group.
Total consumption of nanomagnetic composites in low-loss transformers and other electrical and
electronic devices was 4,820 tons with a value of USD 153.9 million in 2013. It has been forecast418
that the overall market for nanomagnetic materials will at a CAGR of 12.5% between 2014 and
2019. Applying this growth rate to 2013 consumption of nanomagnetic composites and assuming it
continues through 2019 yields the projections shown in the following figure 419.
Figure 9-14: Global market for nano-magnetic composites in electronic and electrical
devices to 2019
EMERGING MARKETS
This section looks at the emerging applications of:
A. Photonic add/drop filters;
B. Optical switches;
C. Optical amplifiers (op amps);
D. Digital image sensors; and
E. Transparent electrodes.
An important device for optical communications and in many other applications is a channel-drop
filter. Given a collection of signals propagating down a waveguide (called the bus waveguide), a
channel-drop filter picks out one small wavelength range (channel) and reroutes (drops) it into
418
BCC Research, Nanomagnetics: Materials, Devices and Markets
419
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.178
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Optical switches are all-optical fibre-optic switching devices that maintain the signal as light from
input to output. In this they differ from traditional switches that connect optical fibre lines which are
electro-optic. Electro-optic switches convert photons from the input side to electrons internally in
order to do the switching and then convert back to photons on the output side. Although some
vendors call electro-optical switches "optical switches," true optical switches support all transmission
speeds. Unlike electronic switches, which are tied to specific data rates and protocols, optical
switches direct the incoming bit stream to the output port no matter what the line speed or protocol
(IP, ATM, SONET). Optical switches may also separate signals at different wavelengths and direct
them to different ports423. Quantum dots can further help to improve the performance of all-optical
switches by allowing for higher switching speeds, smaller size and lower power consumption.
In 2003, Evident Technologies, Inc. issued a United States Patent (Number 6,571,028) for an all-
optical switch or optical transistor. The optical transistor is based upon a saturable absorber or switch
using the company’s EviDots semiconductor nanocrystal quantum dot technologies. The optical
switch has the potential to switch at speeds up to thousands of times faster than current generation
optical switching424. The quantum dots, which are manufactured of lead sulphide or lead selenide
via a thermal precipitation or colloidal growth process, are contained in a matrix or glass, silicon or
other material. The intensity of light required to saturate the absorber depends on the size and
composition of the quantum dots, and the concentration of dots determines how thick a slab of
matrix material is required to produce a given change in intensity of the signal 425.
No quantum dot optical switches are currently on the market, and the timing of their eventual
commercial introduction is unknown. However, given their advantages versus competing
technologies, it is forecast that quantum dot switches could reach the market before 2019 and the
overall optical switch market could exceed USD 1.2 billion by 2019. It is difficult to quantify quantum
dot switches’ potential share of the 2019 optical switch market with any certainty, especially in view
of uncertainty about the timing of their introduction. However, if they capture 2% to 5% of the
optical switch market, the market value would be USD 24 million to USD 60 million (or a mean of
USD 42 million) by 2019. If material costs represent nearly one-third of the total cost of these
devices, the market for PBG nanocomposites in optical switches could reach USD 14 million by
420
http://ab-initio.mit.edu/photons/ch-drop.html
421
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.91
422
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.184
423
http://www.pcmag.com/encyclopedia/term/48554/optical-switch
424
ScienceBlog: Evident Technologies Granted US Patent for Optical Switch based on Quantum Dots, Jun 9,
2003
425
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.91
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2019426.
C OPTICAL AMPLIFIERS ( OP AMPS )
In order to transmit signals in optical communication systems over long distances (>100 km) it is
necessary to compensate for attenuation losses within the fibre. Initially this was accomplished with
an optoelectronic module consisting of an optical receiver, a regeneration and equalisation system,
and an optical transmitter to send the data. Although functional, this arrangement is limited by the
optical to electrical and electrical to optical conversions. Optical amplifiers have been developed to
overcome these drawbacks. Currently the two types of optical amplifiers in most common use are
semiconductor optical amplifiers (SOA) and rare earth doped fibre amplifiers (erbium – EDFA 1500
nm, praseodymium – PDFA 1300 nm)427.
Optical amplifiers having nano-sized semiconductor particles, called quantum dots, show attractive
features such as an ultra-wide operating wavelength range, suppressed waveform distortion in high
power output, and capability of noise reduction (signal regeneration) by limiting amplification. With
these features, the quantum-dot devices have been developed targeting applications in optical
communication systems such as inline, booster, and preamplifiers, and are presently in the stage of
commercialisation. The application is not limited to optical amplifiers, but also includes the light
sources for sensors, gyroscopes, optical coherence tomography, etc., and the gain elements
integrated into wavelength-tunable lasers and mode-locked lasers428. While the development of
quantum dot amplifiers has proceeded rapidly, commercialisation appears to be at least several
years away. Reportedly there is still much room for improving the quality of the crystal to eliminate
polarisation sensitivity and gain inequality. A further commercial obstacle to commercialisation of
quantum dot amplifiers is telecommunications carriers’ large investment in existing amplifier
technologies, especially erbium amplifiers429.
Nanoparticle-based optical amplifiers were not yet available commercially in 2013 and 2014. Global
sales of all types of optical amplifiers are projected to reach USD 2.8 billion by 2019. If quantum dot
PBG nanocomposite devices can capture 10% of this market, the forecast sales would be USD 280
million in 2019. At one-third of the total cost of optical amplifiers for materials, the related
consumption of quantum dot PBG nanocomposites is projected to reach USD 93.3 million by 2019430.
D DIGITAL IMAGE SENSORS
Digital image sensors can be used to record electronic images. The most commonly recognised
application of the digital image sensor is the digital camera. In digital cameras, the image sensor is
used in conjunction with a colour separation device and signal processing circuitry to record images.
The two main technologies used to fabricate the sensors are CCDs (Charge Coupled Devices) and
CMOS (Complementary Metal-Oxide Semiconductors)431.
InVisage Technologies (Menlo Park, Calif.) is commercialising QuantumFilm (QF) technology to
replace the conventional complementary metal-oxide semiconductor (CMOS) image sensor. QF
technology works by suspending quantum dots within a special polymer film. The film is then “spun”
or painted on top of a traditional CMOS wafer. The quantum dot film captures all the light that hits
the top of the chip and sends it directly to the silicon chip. In a conventional CMOS image sensor,
light typically has to pass through layers with metal connections before it hits a photo detector,
which blocks out about half the photons. By putting the film on top of the chip, and by having more
efficient materials, InVisage proposes to create a sensor that is four times more sensitive to light
with twice the dynamic range of the typical CMOS sensor. According to InVisage, its new technology
will enable higher resolution for cameras and much better low-light performance, particularly in
contrast to the sensors used in today’s camera phones.
InVisage Technologies’ first QuantumFilm image sensors, targeting high-end mobile handsets and
smartphones, are scheduled to be deliverd sometime after 2014. It is estimated that 100 million
QuantumFilm sensor-equipped handsets will be sold in 2019. QuantumFilm sensors are expected to
426
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.184
427
Kostuk R (2006), Optical Amplifiers, mimeo
428
Akiyama T, et la. (2006), Quantum-Dot Semiconductor Optical Amplifiers, IEEE LEOS - LASERS & ELECTRO-
OPTICS SOCIETY Newsletter, February 2006 Volume 20, Number 1, p.11
429
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.92
430
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.185
431
https://illumin.usc.edu/101/the-digital-image-sensor/
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cost the same as the CMOS sensors they replace (c. USD 5 each) making a total market value of
USD 500 million in 2019. The exact cost of the quantum dot film in a QuantumFilm sensor is not
known, but according to InVisage, the incremental cost is minimal. For analytical purposes, if the
quantum dot film adds 5% to the cost of the sensor, about USD 25 million worth of quantum dots
will be required to fabricate the USD 500 million worth of QuantumFilm sensors it is estimated that
the market will require in 2019432.
E TRANSPARENT ELECTRODES
432
BCC Research (2014), Nanotechnology: A Realistic Market Assessment p.138
433
Andreas Stadler (2012), Transparent Conducting Oxides — An Up-To-Date Overview. Materials 2012, 5: 661
434
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.69
435
http://cordis.europa.eu/news/rcn/128114_en.html
436
Investorintel: Chinese Firms to launch First Mass Produced 15″ Single-layer Graphene Film, March 27, 2013
437
BCC Research (2014), Nanotechnology: A Realistic Market Assessment, p.163
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438
http://www.luxtera.com/
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Luxtera has currently two main products, among the most advanced on the market:
The LUX62608 OptoPHYs™ are 200G (8 x 26 G) embedded optical modules. OptoPHY offers
customers the flexibility of field replaceable, pluggable optical transceivers by interfacing to
systems via a 100-pin small form factor connector. The OptoPHY optical transceiver sub-
assembly contains eight parallel fibre optic transceivers, each operating at data rates from 1
Gbps up to 26 Gbps and supporting a reach up to 2000 meters over standard single mode fibre.
The LUX42604 QSFP optical modules are faceplate pluggable optical transceivers that meet the
100G (4x26G) PSM4 MSA technical specifications. The LUX42604 delivers full performance up
to 25.78 Gbps per channel.
Key figures for Luxtera:
• Luxtera employs typically 120 people, including at least 30 working in R&D.
• The average revenue of the company is USD 22 million (EUR 19.6 million).
• 2001-2014 fund raising summary: USD 110.6M (EUR 83.2 M) in 6 rounds from 6 investors,
last funded on: March 24, 2014 (see below)
• 2008-2011: Public IPO Secured USD 68 million (EUR 48.9 million) of equity funding for
Luxtera, from venture capital and strategic investors during critical 2008/2009 period in
difficult financial markets
• 2011: Molex Inc. (MOLX) acquires Luxtera Inc’s “active optical cable” business for more than
USD 20 million (EUR 14.4 million). Luxtera rises over USD 22 million (EUR 15.8 million) in
venture capital funding from such firms as Austin Capital, Lux Capital, New Enterprise
Associates, Sevin Rosen Funds and Western Technology Investment
• 2012: Horizon Technology Finance Partners on $7.5 million (EUR 5.8 million) Venture Loan
Facility for Luxtera.
• 2015: Horizon Technology Finance: New loans in the third quarter of 2015, USD 833,000
(EUR 744,000) to Luxtera Inc, an existing portfolio company.
• 2008: Luxtera won a second grant from the Advanced Research Projects Agency (DARPA) to
further develop its high-bandwidth CMOS photonics transceiver technology
Future trends, prospects and expansion: Currently, Luxtera has a partnership with Molex, which
ships 40Gbp/s active optical cables, recognised widely for its best in class power consumption,
performance and reliability. It also entered into a partnership with STMicroelectronics in 2012.
Luxtera’s CMOS Photonics™ technology platform is high-performance, low-cost and scalable for
decades to come.
The next section looks at technologies that have the potential to develop into markets for
nanotechnology in ICT.
A QUANTUM COMPUTING
A quantum computer operates according to the principles of quantum mechanics, the physics of very
small things, such as electrons and photons. In a classical computer, a transistor stores a single “bit”
of information which can either be in an on (1) or off (0) configuration. By virtue of the superposition
principle, a quantum computer holds information (as a ‘qubit’) such that it can exist in two states,
as a 1 and a 0, at the same time. As one qubit can hold two values (1,0) and two qubits can hold
four values, and at any given time (00, 01, 10, and 11) and so on, by increasing the number of
qubits, the computing power of the system increases exponentially. Quantum computing is limited
by its coherence, its ability to retain its multiple states without reverting to a classical bit with only
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a single value439. While quantum computers are better in terms of capacity (useful for image and
speech recognition, real-time language translation, and data-crunching on a large scale the data
from sensors, medical records and stockmarkets), they do not offer improvements in the speed of
downloads or the quality of graphics440.
D-Wave Systems (Burnaby, Canada) is reported to be the world's first quantum computing company.
On May 11, 2011, D-Wave Systems announced D-Wave One, described as "the world's first
commercially available quantum computer," operating on a 128-qubit chipset using quantum
annealing (a general method for finding the global minimum of a function by a process using
quantum fluctuations) to solve optimisation problems441. Major clients of D-Wave Systems include
Lockheed-Martin, Google, NASA, and USC. D-Wave has been granted over 110 US patents and has
published over 80 peer-reviewed papers in leading scientific journals.442 443
In June 2015, QuTech, an initiative by TU Delft and TNO developing quantum technology, received
the approval for a 10-year investment of EUR 135 million from a group of six private and
governmental parties. The aim of the tech-institution is to develop a quantum computer. In 2014,
QuTech was nominated as National Icon in the category of innovative projects that provide extra
support for the citizens of the Netherlands. Since 2010, the company has been receiving financial
support from Microsoft. QuTech has approximately 100 scientists in its employment, a figure they
hope to double in the coming years 445. In October 2015, Intel announced its support for QuTech,
albeit that it has been said that, from Intel’s perspective, practical applications of quantum
computing are still several years away446.
B SPINTRONICS
Spintronics, or spin electronics, refers to the study of the role played by electron (and more generally
nuclear) spin in solid state physics, and possible devices that specifically exploit spin properties
instead of, or in addition, to charge. The prototype device that is already in use in industry as a read
439
WIRED: Google’s Quantum Computer Just Got a Big Upgrade, September 28, 2015
440
The Economist: Quantum computers - A little bit, better, June 20, 2015
441
Gosh A, Mukherjee S (2013), Quantum Annealing and Computation: A Brief Documentary Note, SCIENCE
AND CULTURE (Indian Science News Association), vol. 79: 485
442
http://www.dwavesys.com/our-company/meet-d-wave
443
EXTREMETECH: Did Google’s quantum computer just get the biggest processor upgrade in history? October
1, 2015
444
http://www.dwavesys.com/
445
DAFNE: QuTech Receives €135 Million to Build Quantum-Computer, June 3 2015
446
Forbes Tech: Quantum Computing: From Theory To Reality, September 4, 2015
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head and a memory-storage cell is the giant-magnetoresistive (GMR) sandwich structure which
consists of alternating ferromagnetic and nonmagnetic metal layers. Depending on the relative
orientation of the magnetisations in the magnetic layers, the device resistance changes from small
(parallel magnetisations) to large (antiparallel magnetisations). This change in resistance (also called
magnetoresistance) is used to sense changes in magnetic fields447.
Current efforts in designing and manufacturing spintronic devices involve two different approaches.
The first is perfecting the existing GMR-based technology by either developing new materials with
larger spin polarisation of electrons or making improvements or variations in the existing devices
that allow for better spin filtering. The second, which is more radical, focuses on finding novel ways
of both generation and utilisation of spin-polarised currents. These include investigation of spin
transport in semiconductors and looking for ways in which semiconductors can function as spin
polarisers and spin valves448. Activities in this technology area include:
• NVE Corporation (Eden Prairie, MN, USA) manufactures spintronic products including sensors
and couplers that are used to acquire and transmit data. Their designs use one of two types of
patented spintronic nano-scale structures: spin-dependent tunnel junctions and giant
magnetoresistors (GMR). Both structures produce a large change in electrical resistance
depending on the predominant spin of electrons in a thin metal layer. In this way electron spin
can be converted to an electrical signal compatible with conventional electronics449.
• QuantumWise recently announced the 2015 version of their Virtual NanoLab and Atomistix
ToolKit atomic-scale modelling platform software. This is a research tool to help in the modelling
of spintronics. The new version includes added features such as electron-phonon interaction,
analysis functions for molecular dynamics simulations. Specifically, for spintronics research,
there are improvements for non-collinear and spin-orbit calculations. In addition, spin-orbit
coupling has been updated to perform better. The company also announced that Virtual NanoLab
(but not ATK) is now available free of charge to academic users.450
• Researchers from the Lomonosov Moscow State University together with British scientists
discovered recently that superconductivity is able to promote magnetisation in certain
conditions. Using this effect may lead to faster spintronic devices. The researchers say that
superconducting spintronic devices will demand far less energy and emit less heat compared to
current devices. The superconductors may be useful in the process of spin transportation while
ferromagnetics may be used to control spins451.
C VALLEYTRONICS
Valleytronics is cutting-edge electronics research using the wave quantum number of an electron in
a crystalline material to encode data. The “valley” in valleytronics comes from the shape of the graph
when the energy of electrons is plotted relative to their momentum: the resulting curve features two
valleys. Electrons move through the lattice of a 2D semiconductor as a wave populating these two
valleys, with each valley being characterised by a distinct momentum and quantum valley number.
If the two valleys can be manipulated so that one is deeper than the other, the electrons populate
one valley more than the other. When the electrons are in a minimum energy valley, the quantum
valley number associated with it can be used to encode information452. Developments in this area
include:
• Researchers at the Lawrence Berkeley National Laboratory (LBL) have recently developed a new
pathway to achieving “valleytronics” using two-dimensional (2D) semiconductors. The LBL
researchers believe that this new approach could make valleytronics a more stable alternative
to “spintronics” as a replacement for traditional electronics. The team used the 2D material called
tungsten diselenide in conjunction with a phenomenon known as the “optical Stark effect” to
selectively control photoexcited electrons/hole pairs—excitons—in different energy valleys. The
Stark effect involves the shifting and splitting of spectral lines of atoms and molecules when
447
http://www.physics.umd.edu/rgroups/spin/intro.html
448
Ibid
449
http://www.nve.com/spintronics.php
450
http://www.spintronics-info.com/quantumwise-releases-new-version-their-atomic-scale-modeling-platform-
software
451
http://www.nanotech-now.com/news.cgi?story_id=52350
452
IEEE Spectrum: Is "Valleytronics" the Next Big Thing in Quantum Computing? Februar 5 2015
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The next section looks at the wider environment for nanotechnology and ICT – regulation and
standards, environmental health and safety issues, communication and public attitudes.
453
Ibid
454
http://www.eurekalert.org/pub_releases/2015-11/uot-vcc111215.php
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been run by the European Commission but discussions are still ongoing.
To facilitate regulation, inter alia, a definition of nanomaterials has been defined by the European
Commission in its Recommendation on the Definition of a Nanomaterial - 2011/696/EU. This non-
binding document has also been used by other pieces of regulation to define the term ‘nanomaterial’.
The definition is the following:
“2. ‘Nanomaterial’ means a natural, incidental or manufactured material containing particles, in an
unbound state or as an aggregate or as an agglomerate and where, for 50 % or more of the particles
in the number size distribution, one or more external dimensions is in the size range 1 nm-100 nm.
In specific cases and where warranted by concerns for the environment, health, safety or
competitiveness the number size distribution threshold of 50 % may be replaced by a threshold
between 1 and 50 %.”
Developed in 2011, this definition is undergoing a review process that should have been concluded
in December 2014; an outcome of this review could be a revision of the definition.
The table below lists some key regulatory documents within the European Union as a whole and
within Member States. Nano-specific regulations may come into force at different stages of the
production process (e.g. at the manufacturing stage of a batch of nanomaterials with uses in various
sectors including ICT).
Table 10-1: Overview of regulations for nanotechnology use in Europe
There are also efforts underway within the research community to develop a testing strategy for
engineered nanomaterials. These include the ITS-NANO project under FP7-NMP which seeks to
establish a roadmap for the development of advanced tools and databases that help to assess the
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455
http://www.its-nano.eu
456
Décret n° 2012-232 du 17 février 2012 relatif à la déclaration annuelle des substances à
l'état nanoparticulaire pris en application de l'article L. 523-4 du code de l'environnement
457
Koninklijk besluit betreffende het op de markt brengen van als nanodeeltjes geproduceerde stiffen or Arrêté
royal relatif à la mise sur le marché des substances manufacturées à l’état nanoparticulaire
458
US Food and Drug Administration http://www.fda.gov/
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134
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459
Marquart, H., Heussen, H., Le Feber, M., Noy, D., Tielemans, E., Schinkel, J., West, J., Van Der Schaaf, D.,
2008. 'Stoffenmanager', a web-based control banding tool using an exposure process model. Ann. Occup.
Hyg. 52, 429-441.
460
Van Duuren-Stuurman, B., Vink, S., Verbist, K.J.M., Heussen, H.G.A., Brouwer, D., Kroese, D.E.D., Van Niftrik,
M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-based tool for risk
prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-541.
461
ECHA, 2012. Chapter R.14: Occupational exposure estimation in: Anonymous Guidance on Information
Requirements and Chemical Safety Assessment., Version: 2.1 ed. European Chemicals Agency, Helsinki,
Finland.
462
Ibid
463
Watkinson, A.C., Bunge, A.L., Hadgraft, J., Lane, M.E., 2013. Nanoparticles do not penetrate human skin - A
theoretical perspective. Pharm. Res. 30, 1943-1946
464
Le Feber, M., Kroese, E.D., Kuper, C.F., Stockmann-Juvala, H., Hyytinen, E.R., 2014. Pre-assigned hazard
bands for commonly used nanoparticles. TNO2014 R11884.
465
M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-based tool for risk
prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-541.
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Details of the hazard bands derived for each material are given below, except for silica. The hazard
banding of silica nanoparticles has already been reported466 467.
GALLIUM ARSENIDE
No toxicity studies on nano-GaAs were encountered in public literature. According to data from the
REACH dossier of GaAs, (powdered) GaAs has limited solubility in water (based on released As3+
ions). GaAs is marketed as an article made from very pure (99.9999%) crystalline bulk material,
predominantly in the shape of wafers468, implying an even lower water solubility. Therefore, applying
the methodology of van Duuren et al. (2012), the hazard characteristics of the parent material are
used.
GaAs is classified as carcinogenic, but not mutagenic (based on sufficient evidence) by the EU. It
should be noted that the classification for carcinogenicity was based on inhalation studies with
micronised powdered GaAs, and that the relevance of these studies for human exposure to
crystalline GaAs is questioned469. Based on the classification of the bulk material, nanoGaAs is
attributed hazard band D.
GALLIUM NITRIDE
No relevant toxicity studies on nano-gallium nitride were encountered in public literature. Gallium
nitride wafers are virtually insoluble in water, even in dilute acid 470, and therefore, applying the
methodology of van Duuren et al. (2012), the hazard characteristics of the parent material are used.
Gallium nitride is not classified for any toxicity by the EU. However, this absence of classification
was based on the lack of data. Besides the gallium ions, which are not considered relevant for gallium
nitride since it is insoluble in water471, only one structurally-similar compound was found using the
on-line ChemID database: gallium phosphide, which was characterised as being 80% similar with
gallium nitride. For this compound also no relevant toxicity data were found, meaning read-across
could not be employed. Therefore, no hazard banding could be derived.
GRAPHENE
Graphene is composed of sp2-hybridised carbon atoms arranged in a two-dimensional structure. The
various forms of graphene include few-layer graphene, reduced graphene oxide, graphene
nanosheets and graphene oxide (GO)472.
The UK government body, the Medicines and Healthcare Products Regulatory Agency (MHRA), and
the US Food and Drug Administration (FDA) are now reviewing all forms of graphene and
functionalised graphene oxide (GO) because of their poor solubility, high agglomeration, long-term
retention, and relatively long circulation time in the blood473.
Currently, limited information about the in vitro and in vivo toxicity of graphene is available (Seabra,
et al. 2014). The toxicity profiles of graphene and graphene oxide (GO) nanoparticles remain difficult
to separate, since their characterisation, bulk and chemical composition are very similar at the
nanometre length scale (Nezakati, et al. 2014).
In vitro graphene has been demonstrated to be cytotoxic, be it overall to a lesser degree than carbon
nanotubes (Seabra, et al. 2014). However, the reliability of this conclusion can be doubted since
Seabra et al. stated that graphene showed an inverse dose-relationship, being more cytotoxic than
466
Le Feber, M., Kroese, E.D., Kuper, C.F., Stockmann-Juvala, H., Hyytinen, E.R., 2014. Pre-assigned hazard
bands for commonly used nanoparticles. TNO2014 R11884.
467
M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-based tool for risk
prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-541.
468
Bomhard, E.M., Gelbke, H.-., Schenk, H., Williams, G.M., Cohen, S.M., 2013. Evaluation of the carcinogenicity
of gallium arsenide. Crit. Rev. Toxicol. 43, 436-466
469
Ibid
470
Jewett, S.A., Makowski, M.S., Andrews, B., Manfra, M.J., Ivanisevic, A., 2012. Gallium nitride is biocompatible
and non-toxic before and after functionalisation with peptides. Acta Biomater. 8, 728-733
471
Foster, C.M., Collazo, R., Sitar, Z., Ivanisevic, A., 2013. Aqueous stability of Ga- and N-polar gallium nitride.
Langmuir 29, 216-220.
472
Seabra, A.B., Paula, A.J., De Lima, R., Alves, O.L., Durán, N., 2014. Nanotoxicity of graphene and graphene
oxide. Chem. Res. Toxicol. 27, 159-168.
473
Begum et al. 2011 cited in Nezakati, T., Cousins, B.G., Seifalian, A.M., 2014. Toxicology of chemically modified
graphene-based materials for medical application. Arch. Toxicol. 88, 1987-2012.
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carbon nanotubes at low concentrations. The only elaborate comparative study reported by Seabra
et al., refers to genotoxicity towards human fibroblast cells. GO proved to be the most potent
genotoxic agent compared to iron oxide (Fe304), titanium dioxide (Ti02), silicon dioxide (Si02), zinc
oxide (ZnO), indium (In), tin (Sn), core—shell zinc sulphate-coated cadmium selenide
(CdSe(3)ZnS), and carbon nanotubes.
Intratracheal instillation of 50 µg GO in mice caused severe pulmonary distress after inhalation
causing excessive inflammation, while the amount of non-functionalised graphene instilled did not474.
Single intravenous (i.v.) injection of graphene oxide into mice at a dose of 10 mg/kg bw accumulated
in the lung resulting in pulmonary oedema and granuloma formation, with NOAEL of 1 mg/kg bw 475.
Furthermore, surface functionalised graphene (PEGylated) appears to be far less toxic: no toxic
effects after single i.v. injection of 20 mg/kg bw (Yang, et al. 2011). In mice, PEGylated GO materials
showed no uptake via oral administration, indicating limited intestinal absorption of the material,
with almost complete excretion. In contrast, upon i.p. injection in mice, PEGylated GO was found to
accumulate in the liver and spleen476.
The toxicity of graphene is dependent on the graphene surface (the chemical structure or the nature
of the functionalised coatings), size, number of layers, cell type, administration route (for in vivo
experiments), dose, time of exposure, and synthesis methods (Seabra, et al. 2014). Generalisations
are therefore hard to make, but graphene nanostructures are not fibre-shaped and theoretically may
be assumed to be safer than carbon nanotubes (Seabra, et al. 2014).
Based on the scarce available evidence, and in spite of its theoretical advantage in relation to carbon
nanotubes, it cannot be excluded that some forms of graphene will be as potent a toxicant as carbon
nanotubes. Therefore, graphene is assigned to hazard band E.
MOLYBDENUM DISULPHIDE
474
Duch, M.C., Budinger, G.R.S., Liang, Y.T., Soberanes, S., Urich, D., Chiarella, S.E., Campochiaro, L.A.,
Gonzalez, A., Chandel, N.S., Hersam, M.C., Mutlu, G.M., 2011. Minimising oxidation and stable nanoscale
dispersion improves the biocompatibility of graphene in the lung. Nano Letters 11, 5201-5207.
475
Zhang, X., Yin, J., Peng, C., Hu, W., Zhu, Z., Li, W., Fan, C., Huang, Q., 2011. Distribution and biocompatibility
studies of graphene oxide in mice after intravenous administration. Carbon 49, 986-995
476
Yang, K., Wan, J., Zhang, S., Zhang, Y., Lee, S.-., Liu, Z., 2011. In vivo pharmacokinetics, long-term
biodistribution, and toxicology of pegylated graphene in mice. ACS Nano 5, 516-522. (Cited in Seabra, et al.
2014)
477
Van Duuren-Stuurman, B., Vink, S., Verbist, K.J.M., Heussen, H.G.A., Brouwer, D., Kroese, D.E.D., Van Niftrik,
M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-based tool for risk
prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-541.
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present. Some of the identified substances may not necessarily be engineered nanomaterials.
The production phase of ICT products on industrial scale consists mainly of automatic processes,
with employees only engaged in product quality control or system engineering. In addition, most
processes are performed in cleanrooms and/or under well-controlled conditions, as dust is a major
threat to the quality of the products. Nevertheless, spray scenarios for coating normally result in
high exposure concentrations, so potential exposure cannot be neglected. In the situation of a
manual process without proper exposure control measures (e.g. local exhaust ventilation,
cleanroom), employees may be exposed to relatively higher concentrations. Lastly, during the end-
of-life phase several metals may be present in the ICT product, which can be worthwhile to recycle.
Recycling of these metals may involve, for example, shredding of ICT products, and any engineered
nanomaterials could become airborne. However, as the shredded products only will contain a small
amount of engineered nanomaterials, potential exposure to engineered nanomaterials during this
process will be relatively low.
In conclusion, the use of nanotechnology ICT products results in exposure band 1 (consumers and
workers), whereas during the production of nanotechnology ICT products exposure band 2 (workers)
is believed to be realistic. Furthermore, during the end-of-life phase an exposure band 1 (workers)
is realistic.
Hazard band A B C D E
Exposure band
1 3 3 3 2 1
2 3 3 2 2 1
3 3 2 2 1 1
4 2 1 1 1 1
Key:
Hazard: A = lowest hazard and E = highest hazard;
Exposure: 1 = lowest exposure and 4 = highest exposure;
Overall result: 1 = highest priority and 3 = lowest priority (Van Duuren-Stuurman, et al. 2012)
Risks based on the hazard and exposure banding applied to the ICT sector are listed the table below.
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The highest priority is for graphene and crystalline silica during the production, use and end-of-life
phases, while gallium arsenide and nanosilver have intermediate priority in those phases. Molyb-
denum disulphide and amorphous silica also have intermediate priority in the production phase, but
low priority during use and end-of-life phase in view of a lesser potential of exposure in those phases.
For gallium nitride and tungsten selenide no adequate data were available to perform hazard and
exposure banding.
This section on human health and safety is presented in full in the Annex: Human Health and Safety.
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A second search was done to obtain an indication of where the interests of academics lie. Using
Google Scholar480, it was found that nano-electronics appears to be a more active research area
than neuromorphic engineering. Actually, it is more likely that researchers working in both fields,
but neuromorphic engineering in particular, use specialist terms in describing their work, not the
broad terms covering the entire field.
478
The search was carried out using a selection of nano-ICT related keywords: "Network-on-chip", “D-RAM”,
"Biocomputing", "Nanoelectronic", "Spintronic", "Neuromorphic", "Giant magnetoresistance",
"Microelectromechanical system", "Quantum computing" Nano, "Avalanche diode", "Magnetic tunnel
junction", "Spin torque", "Graphene electronics", "Valleytronics", "Photonic crystal cavity", "Tunnel FET",
"Spin transistor", "Nanoelectromechanical system", "Programmable metallisation cell", "Nanoresonator"
"Nanowire MOSFET", "Nanowire electronic", "Semiconductor nanodevices", "Nano-optomechanical", "Silicon-on-
insulator FET", "Nano-ICT", "Nano-electronic memory", "Nano-optomechanical system", and "Nanoribbon
heterojunction".
479
Ibid
480
Google Scholar is an online database of many of the peer-reviewed online journals of Europe and the US, plus
books and non-peer reviewed journals, containing an estimated 160 million documents in 2014 (Orduña-
Malea, E, et al. (2014). About the size of Google Scholar: playing the numbers. Granada: EC3 Working
Papers, 18: 23 July 2014.)
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The types of news articles that have used the terms neuromorphic and nano-electronics was
analysed using a sample of the top 100 news articles from 2014 and 2015 as identified using the
Google search engine. A higher proportion of articles using the term neuromorphic are from general
interest of general science type publications (e.g. daily newspapers, wired magazine, articles in
financial magazines) than those articles using the term nano-electronics. This supports the fact that
neuromorphic engineering, though a booming research field has also become a media “buzz-word”
while nano-electronics has not.
Figure 10-1: Type of website for the top 100 news items for neuromorphic and nano-
electronics
Graphene is a nanomaterial with huge and growing potential for ICT applications due to its superior
conductive and other properties which researchers are increasingly manipulating and exploiting.
Research in graphene is driven by electronic applications as evidenced by the share of academic
publications related to “graphene” and “graphene electronics” applications, as shown in the figure
below481.
481
Note: 2015 data only to early December.
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Trends over time in Google Scholar results for the “graphene” and “graphene
electronics”
160
Number of results ('000s)
140
120
100
80
60
40
20
0
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Figure 10-2: Trends over time in Google Scholar results for the “graphene” and “graphene
electronics”
482
www.nanopinion.eu
483
www.nanodiode.eu
484
Analysing previous experiences and European projects on nanotechnology outreach and dialogue and
identifying best practices, Daan Schuurbiers and De Proeffabriek, March 2014, (Accessed at
http://www.proeffabriek.nl/uploads/media/NanoDiode_WP1_Best_Practices.pdf in November 2015)
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nanotechnologies to be applied. For example, they aim to bring groups of potential nanotechnology
‘users’ (industrial customers as well as consumers) together with researchers working on near-
market products in order to facilitate discussions which could help steer the research towards social
values and user needs.
In addition to these FP7 projects, two population surveys in Germany provide some data on the
public’s attitudes (Zimmer et al, 2009)485, as well as a survey among young people conducted within
the framework of the NANOYOU project (NANOYOU, 2010) 486 and a recent survey in the USA
(Shipman, 2010)487. OECD work on public engagement with nanotechnology has led to the
production of a guide to assist policymakers (OECD, 2010)488.
Table 10-7: Assessments by the public of various applications of nanotechnology
From German online discourses and a questionnaire survey (Böl et al. 2010)
Relatively favourable situations may exist if citizens have concrete experiences with, or expectations
towards specific applications; they tend to support applications “that are linked to a wider social
good or perceived individual benefit” (Böl, 2010; Fleischer et al., 2012) 489,490.
485
Zimmer, R., Hertel, R., Böl, G.F., 2009, “Public perceptions about nanotechnology: Representative survey and
basic morphological-psychological study”, Bundesinstitut für Risikobewertung (BfR)
486
Nanoyou, 2010 http://cordis.europa.eu/publication/rcn/15319_fr.html
487
Shipman, M., 2010, “Hiding risks can hurt public support for nanotechnology”, News Services NCSU
488
http://www.oecd.org/sti/biotech/49961768.pdf
489
Böl, G.F., Epp A., Hertel, R., 2010, “Perception of nanotechnology in internet-based discussions”,
Bundesinstitut für Risikobewertung (BfR)
490
Fleischer, T., Jahnel J., Seitz S.B., 2012, “NanoSafety – Risk governance of manufactured nanoparticles”,
European Commission
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11 CONCLUDING SUMMARY
Nanotechnology is seen to be contributing to the goals of making smaller, faster and more robust
devices that can process and store more, faster and better.
Policy supports in Europe include the EU RTD Framework Programmes projects, ERA-NET491s,
European Technology Platforms and Networks of Excellence, as well as the Digital Agenda for Europe.
Member States support nanotechnology within broad science and technology initiatives (e.g. the
United Kingdom, the Netherlands) and through special initiatives such as IMEC492 in Belgium and
the Iberian Nanotechnology Laboratory493 in Portugal.
The strongest publishing countries in 2014 were China and the US, followed by Korea, Japan,
Germany, India and the United Kingdom. Of the EU28, the strongest in publications in 2014 were
Germany, the United Kingdom, France, Italy and Spain.
The leading EU28 countries for nanotechnology and ICT are Germany, France and the United
Kingdom in the Framework Programmes (FP6 and FP7) are also the leaders in publication output
2000-2014 and, together with the Netherlands, are the top four for patent applications (as measured
by patent families in 1993-2011). Belgium also performs strongly in all three areas.
In terms of individual organisations in the EU28, the CNRS 494 (FR), the CEA495 (FR) and IMEC (BE)
perform the most strongly in projects and patents while the strongest publishers are generally
universities such as Cambridge, Paris XI Sud, Dresden and Manchester (albeit with IMEC in third
place).
The global market for products in nanotechnology and ICT is expected to grow from USD 2 billion in
2013 to over USD 10 billion in 2019. 84 ICT-related products using nanotechnology are commercially
available on the market. Nanotechnology occurs mostly in components including data storage but
also strongly in materials such as electrostatic dissipative coatings.
The strongest companies in nanotechnology and ICT in projects are STMicroelectronics, Philips and
Infineon; and in publications they are IBM, Samsung and NTT. In EPO patents, companies from the
US and Korea lead while European company Infineon Technologies (DE, AT) appears in fourth place
and is joined by Philips (NL, DE), both strong FP project performers.
491
Also ERA-NET plus
492
Interuniversitair Micro-Electronica Centrum, http://www2.imec.be/be_en/about-imec.html
493
http://inl.int/
494
Centre National de la Recherche Scientifique
495
Commissariat à l'énergie atomique et aux énergies alternatives
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ANNEXES
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A Introduction
This paper outlines the main methodologies used in the NanoData project.
The data were in large part identified using keywords to search existing databases (e.g. for
publications and patents) and to select projects (from eCorda) and products (e.g. from product
databases). The report explains how the keywords were identified and what quality control measures
were put in place.
It should be noted that eight sectors were included in the work – construction, energy, environment
health, ICT, photonics, manufacturing and transport. Thus, the data are not comprehensive across
all of nanotechnology. They are, instead, representative of the sectors selected within the context
of the overall project for the European Commission.
B Development of keywords
The keywords were identified from known data sources, web searches and expert input. They were
validated through discussions with consortium members496 (where they had expertise and
experience in the area concerned) and other experts. Following that validation process, the keywords
were also tested by one or both of the following methods:
• The word ‘nano’ and the keywords were used to select the FP projects relevant to the sector
(and sub-sectors if appropriate). The projects identified were checked manually for false
positives. False negatives were also identified (projects that were expected to be selected that
were not). The keywords were refined to optimise the number of projects correctly selected.
• The keywords were used to select publications. The lists of publications were checked, in part
manually and in part semi-automatically using the CWTS VOSViewer bibliometric mapping tool
(http://www.vosviewer.com/Home). Using the tool, it was possible to see how terms group
together in publication space (by their proximity on a VOSViewer map) and how often they occur
(by their size on the VOSViewer map). Thus, it was possible to determine which terms would be
the most significant in the sector and also which terms would be likely to cause false positives.
For example, in the partial map for nanotechnology and health below (bottom left corner) it can
be seen that a very important term is ‘scaffold’, and related terms are about tissue and bone
engineering. Moving further to the right, the related term ‘biocompatibility’ is seen and nearby
the significant and related but more generic terms ‘surface’, ‘morphology’ and ‘synthesis’.
496
Partners of the Joint Institute for Innovation Policy for this project i.e. CWTS, Frost & Sullivan,
Joanneum Research, Oakdene Hollins, the Nanotechnology Industries Association, Tecnalia and TNO.
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Additional terms could also be identified for inclusion in the keyword list.
It should be noted that, where the use of a keyword could lead to false results, the keyword was
omitted. This inevitably leads to some data of relevance being omitted from the resource base of
the project, the alternative being the inclusion of much irrelevant information. For example, some
words (e.g. photodetector, laser, photolithography) were omitted from the keywords for photonics
as they have much wider applications that photonics alone.
In the searches, keywords were truncated to maximise the possible results. For example, in energy,
“thermoelectric*” could identify data related to “thermoelectric”, “thermoelectrics”,
“thermoelectrical” and “thermoelectricity”, the * indicating the truncation.
Where possible, both British and American spellings were included (e.g. tumour and tumor) as were
alternative spellings (e.g. orthopaedic and orthopedic).
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Table A: Number of actual observations and missing values for each of the eCorda
variables used for the NanoData analysis.
Number of observations
Variable FP6 FP7 Total
Actual Missing Actual Missing Actual Missing % Missing
Project ID 10,027 0 25,238 0 35,265 0 0.0%
In the eCorda database, the EC contribution per project shows some small differences between the
data presented by project (project database) and the data presented by participant (participant
database). The table below illustrates the differences, both in millions of euros and as shares of the
EC contribution. It can be seen that the difference in EC contribution between the project and
participant data is almost zero in FP7 and small in FP6. However, the differences can become
significant when the data is aggregated.
497
In FP6 these were called Priorities and in FP7 Work Programmes.
498
The report uses ISO 2-digit codes for countries. See http://www.iso.org/iso/country_codes
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Table B: Number of projects and EC contribution for the project data and participant data
in eCorda
Number of projects EC contribution Difference Difference
(MEUR) (Project – %
Project Participant Project Participant Participant)
Data Data Data (MEUR)
Data
FP
FP6 10,027 10,027 16,692.320 16,653.860 38.460 0.23%
FP7 25,238 25,238 44,917.330 44,917.200 0.130 0.00%
Total 35,265 35,265 61,609.650 61,571.060 38.600 0.06%
NT
NT-FP6 908 908 1,702.740 1,695.500 7.250 0.43%
NT-FP7 2,636 2,636 4,660.840 4,660.750 0.090 0.00%
Total 3,544 3,544 6,363.580 6,356.250 7.340 0.12%
C1 Classification of projects
In order to identify the baseline set of nanotechnology-related projects for the NanoData work, a
search was made for all FP projects that contained ‘nano’ 499 in the title or abstract of the project.
3,544 projects were selected in this way 500, of which 74% were FP7 projects and 26% were FP6
projects. Comparing the distribution of projects between FP6 and FP7 for nanotechnology and for
the two FPs overall, it is found that the distributions are very similar the latter being 72% in FP7 and
28% in FP6. Nanotechnology projects make up 10% of Framework Programme projects, the share
increasing slightly from FP6 (9.1%) to FP7 (10.4%).
The table below shows the distribution of total FP projects and of nanotechnology projects.
499
The term “nano” could appear as a part of a word (e.g. nanotechnology, nanoscience, nanomaterial,
nanoscale), as a part of compound word separated with hyphen (e.g. nano-science) or as an independent
word “nano”.
500
Unlike the other sectors considered by the project (HT, EN, PH, MF), for ICT additional projects were identified
by use of keywords such as graphene. These were judged to be too important in ICT to be omitted. This did,
however, result in the total number of nanotechnology projects being different for ICT (4,143) and the other
sectors (3,544).
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The 3,544 projects relevant to nanotechnology were subjected to a search using the sector keywords
to identify projects relevant to each sector. This search was undertaken using the keywords identified
for each sector. The project details for the selected projects were reviewed manually, where possible,
as a further check of the quality of the outputs of the keyword search process.
For example, using the method described above, 944 projects were categorised as being related to
nanotechnology and health, approximately 27% of total nanotechnology projects. Using the
keywords identified for each of the five health sub-sectors501, a further classification could be made.
In addition, nanotechnology projects relevant to health but not specifically to any of the five sub-
sectors were categorised as Other. In this way, the breakdown of health nanotechnology projects
was found to be: cancer 26% (CT); infectious diseases 7.8% (ID); cardiovascular diseases 5.2%
(CV); neurodegenerative diseases 4.6% (ND); and diabetes (2.2%) (DB) with Other being 62%
(OTH).
Where projects were classified as belonging to more than one sub-sector, a proportion of each such
project was allocated to the sub-sector concerned. Thus a project relevant to cardiovascular disease
and cancer would be allocated 50% to cardiovascular disease and 50% to cancer. The aim was to
ensure an accurate analysis of the FP project data and to minimise double counting. The table that
follows shows the number of project overlaps and the distributions of fractions of projects for the
health sub-sectors.
501
Cancer, cardiovascular disease, diabetes, infectious diseases and neurodegenerative diseases.
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Total CT CV ID NE DB Other
Projects without 883 196 23 48 24 11 581
overlaps
Projects with overlaps: fractions as allocated
CT & ID 17 8.5 8.5
CT & CV 12 6 6
CT & ND 9 4.5 4.5
CV & ID 5 2.5 2.5
CV & ND 4 2 2
CT & DB 4 2 2
CV & DB 3 1.5 1.5
ND & DB 2 1 1
CT, ID & ND 1 0.33 0.33 0.33
CT, ND & DB 1 0.33 0.33 0.33
CT, CV & ID 1 0.33 0.33 0.33
CT, CV, ID & ND 1 0.25 0.25 0.25 0.25
ID & ND 1 0.5 0.5
Sum of fractions 61 22 13 12 9 5 0
Total 944 218 36 60 33 16 581
nanotechnology
and health
In order to have harmonised variables across both Framework Programmes, some names and coding
of variables were required. These included the following:
i) Harmonising the participant types. The categories used in this report are presented in the table
below. In the tables of top performers, if the same organisation appeared in FP6 and FP7, the
FP7 code was used.
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ii) Introducing a classification of instruments in order to allow enhanced comparison between the
varieties of instruments. The categorisation follows that of Arnold et. al (2012)502.
Action Instrument FP
502
In their work Arnold et. al. (2012) Understanding the Long Term Impact of the Framework Programme
classifies the instruments of FP4, FP5 and FP6 into four categories that are used as guidance for our
classification. For FP7 the classification is done by authors of this report.
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C3 Treatment of decimals
As a general rule, the data in the tables and figures are produced by utilising the method of first
summing the unrounded figures and then rounding the sum. Due to this process, some totals may
not correspond with the sum of the separate figures (generally presented as limited to one decimal).
Code Description
HES Higher or secondary education est.
PCO Private companies excluding SMEs
REC Research organisations
SME Small and medium-sized enterprises
OTH Other (incl. public bodies and bodies
with unknown organisation types)
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D Publications
Identification of publications relied on analysis of the data in the database at CWTS (the Centre for
Science and Technology Studies, Leiden University, the Netherlands), data that is based on that in
the Web of Science506.
The CWTS database is organised and structured such that it allows (dynamic) field delineation and
the collection of relevant publications. Hence it was possible to identify nanoscience and
nanotechnology (NST) publications and, within those, to identify publications relevant to the sectors.
More specifically, publications were sought within the NST group using the keywords. In addition,
using the tools available at CWTS, related publications could be identified and included in the output.
Data available from the resource at CWTS included the journals in which the publications are found,
the date of publication and the doi (digital object identifier). For licensing reasons, some of the data
in the database at Leiden can be accessed by external parties only in aggregate form. For example,
personal details of individual researchers cannot be accessed (e.g. address, email, phone number).
The report uses ISO 2-digit codes for countries. See http://www.iso.org/iso/country_codes
503
Data was also analysed from countries outside of the EU28 namely Iceland (IS), Israel (IL), Norway (NO),
Switzerland (CH) and Turkey (TR).
504
GB is also used
505
GR is also used
506
http://thomsonreuters.com/en/products-services/scholarly-scientific-research/scholarly-search-and-
discovery/web-of-science.html
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E Patents
The patents analysed were collected from the database PATSTAT. That database includes patents
from over 30 patent offices e.g. the European Patent Office, the US Patent Office and the Japanese
Patent Office.
All patent offices worldwide tag nanotechnology-related patent applications using a special symbol
of the International Patent Classification (IPC), namely B82Y. This special symbol is also part of the
CPC (Co-operative Patent Classification). The core dataset of nano-related patents were selected
using this special symbol (B82Y) from both the IPC and the CPC classifications.
All patent applications at the USPTO, the EPO and PCT (WIPO) classified as B82Y were identified in
PATSTAT as well as the (simple) patent family to which they belong. From all these patent families,
only patent applications at the USPTO, the EPO and PCT (WIPO) were collected. Such use of multiple
patent offices helps to diminish the bias that might be caused by the so called ‘home advantage’
effect, i.e. the propensity of nationals to file the first patent application in their own country. By
analysing across these three patent authorities a less biased overview of nanotechnology patents
worldwide can be obtained.
As the patent information is being collected from more than one patent authority, and given that
the same invention might be protected in more than one of these patents authorities, the (simple)
patent families are used to avoid multiple counting of the same invention.
The identification of patents by sector from amongst the nanotechnology patents was based in most
cases on the combination of two strategies. First, all patents including in their title and/or abstract
at least one relevant keywords for a particular sector were retrieved. Second, to ensure that the
patents retrieved in the first step are truly related to the sector, a number of representative IPC
symbols of the sector were selected from PATSTAT507. For example, for the nanotechnology patents
related to the health sector, the IPC symbols related to ‘Pharmaceuticals’ and ‘Medical technology’
were used. However, it was not possible to undertake this second step for all sectors as for some
(e.g. manufacturing) there were no appropriate IPC symbols.
Organisations and/or individuals are listed in patent applications, these being applicants and/or
inventors. This information is used in the identification of companies, universities and other research
organisations active in patenting. The year of reference used is the year when the oldest priority of
each patent family was applied (the closest date to the invention). The report uses ISO 2-digit
codes508 for countries.
F Products
Products were identified primarily through keyword, sector and sub-sector searches of reports and
databases. This search strategy was based on a triangulation approach making use of
complementing perspectives. For all perspectives the NanoData team made use of the sector specific
lists of key words.
The first step was to use peer-reviewed and grey literature on products in the different sectors509 as
well as existing market reports510. The market reports were used to identify where nanotechnology
is being applied already in products as there are many reports that appear to identify products but
no product is for sale at a commercial level, being at the research stage or for very limited supply
e.g. to the research community or for test purposes. These investigations were then complemented
by querying web-based databases on nanotechnology products such as AZONANO511, Nanowerk512,
507
PATSTAT also contains a table mapping 44 industrial sectors and the IPC classification. The linkage between
technology areas and industrial sector is described in Schmoch et al (2003), “Linking Technology
Areas to Industrial Sectors”, final report to the European Commission, DG Research.
508
http://www.iso.org/iso/country_codes
509
E.g. Nanomedicine: Nanotechnology, Biology, and Medicine 9 (2013) 1–14, Hessen Nanotech (2008)
Applications of Nanotechnologies in the Energy Sector.
510
See BCC Research www.bbcresearch.com
511
http://www.azonano.com/
512
http://www.nanowerk.com/
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the consumer products inventory of the Project on Emerging Nanotechnologies513, the product
database of understandingnano.com514, the Nanoinformationsportal of the Österreichische Agentur
für Gesundheit und Ernährungssicherheit GmbH515, the Danish Inventory of Nanoproducts516 and the
nanowatch.de database517. Further sector-specific databases, such as the German database for
medical practitioners and the database on European public assessment reports of the European
Medicines Agency518, were used for the identification and classification of nanotechnology related
products in health, for example.
By querying databases on existing innovation policy projects, initiatives and industry platforms such
as NANORA519, the Nano-Map of the German Federal Ministry of Research520, the database on
photonic companies compiled by EPIC, the members directory of SEMI 521, and the Nano-Bio
Manufacturing Consortium (USA)522, additional enterprises active in nanotechnology sectors were
identified.
A third perspective on products was developed by gathering additional information about the
products from company websites identified in previous work, commercial databases and open
sources of information on the web. The information was verified through additional searches (e.g.
of product data sheets and company websites).
The information in the database was extensively verified. Where, for example, it was found that a
product was identified but not verified, searches were made of sources including reports and
company websites to check the information. Contact was also made, in some cases, directly with
the company in order to ratify the existence on the market of the product. While some other
databases actually state the level of known accuracy of their information (e.g. the entries in the
Woodrow Wilson database are classified using a system that has categories from level 1 (extensively
verified claim) to level 5 (not advertised by manufacturer – claims made only by third party)) others
are not specific.
In NanoData, the aim is only to include products that can be verified.
G Other information
Several types of information are provided on the NanoData site as fixed text where data is limited
or one-off. These include information on markets and wider economic data, as well as reports on
environmental health and safety and information about regulation and standards.
Markets
The market data is based on available sources of information and sources of Frost & Sullivan and
BCC Research, who gather their information through discussions with practitioners (e.g. company
representatives) and open sources (e.g. commercial reports, web sites). The aim was to track,
evaluate and measure the activities of major industry participants in the nanotechnology arena,
looking at markets and usage of nanotechnology. The activities included the definition and
specification of nano-materials and nano-enabled products, identification of current and upcoming
products and applications, accumulating qualitative and quantitative data, identification and
mapping of EU participants and last but not the least, identification and analysis of target markets.
A wide set of definitions, categorisations, data collection and forecasting methods were available.
Data gathering was driven by experienced analysts and based on a data-rich portfolio of previous
EU and OECD projects as well as on internal Frost & Sullivan databases and consortium members,
513
http://www.nanotechproject.org/cpi/
514
http://www.understandingnano.com/nanotechnology-product-suppliers.html
515
http://nanoinformation.at/produkte.html
516
http://nanodb.dk/
517
http://www.bund.net/nc/themen_und_projekte/nanotechnologie/nanoproduktdatenbank/
518
http://www.ema.europa.eu/
519
http://www.nanora.eu/
520
http://www.werkstofftechnologien.de/en/
521
http://www.semi.org/en/Membership/MemberDirectory/
522
http://www.nbmc.org/members-only/
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and public database. European Patent Office523, PRODCOM524 and patentlens525 databases could be
used to provide in-depth information about a particular technology and to identify the key industry
participants dominating the sector. Analysis of key value chains was undertaken and corroborated
with other work-streams. The information thus acquired would be verified with the help of an array
of primary interviews with leading technology researchers, industry experts and other active
stakeholders.
The range of primary and secondary research processes would be followed by the application of
innovation diffusion tools in order to forecast probable market scenario of the future. This would also
include estimating the shape of the diffusion curve and prediction of market development of nano-
enabled products.
European documents:
• Regulation concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals
(REACH) - 1907/2006(EC);
• Regulation on Medical Devices - 2012/0266(COD); and
523
https://www.epo.org/searching.html
524
http://ec.europa.eu/eurostat/web/prodcom
525
https://www.lens.org/lens/search?n=10&q=nanotechnology&p=0
526
Van Duuren-Stuurman, B., Vink, S., Verbist, K.J.M., Heussen, H.G.A., Brouwer, D., Kroese, D.E.D., Van Niftrik,
M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-based tool for risk
prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-541.
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National documents:
• Decree on the annual declaration on substances at nano-scale - 2012-232 (France);
• Royal Decree regarding the Placement on the Market of Substances manufactured at the Nano-
scale (Belgium); and
• Order on a Register of Mixtures and Articles that contain Nanomaterials as well as the
Requirement for Manufacturers and Importers to report to the Register – BEK nr 644 (Denmark).
H Concluding remarks
This Annex outlines the main methods for the selection of data for analysis, some data sources, the
aggregation of data classes in order to enable analysis (mainly for the FP projects) and the ways in
which data was analysed. References are made to some of the main quality control issues.
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Asterisks are used to indicate that part of a word is missing. For example, the search for “bio-
comput*” would identify data related to “bio-computing” and “bio-computer”. Thus one search term
was used to cover each of the words with multiple possible endings. In addition, multiple spellings
were included, not all of which are shown here (e.g. US spelling of aluminium (aluminium) and
hyphenated words including MOS-FET, nano-ICT).
3-d integration
3-d stacking
Aluminium arsenide
Aluminum arsenide
Antimonide
Avalanche diode
Biocomput*
Bio-comput*
Black phosphorous
Black phosphorus
CBRAM
CMOS
CNTFET*
CNT-FET*
Complementary metal-oxide semiconductor*
Conductive bridging RAM
DNA comput*
DRAM
Dynamic random-access memor*
Electro-conductive coatings
Electronic* shield*
Electro-optical
Electrostatic discharge prevention
Electrostatic discharge protection
Electrostatic dissipative applications
Electrostatic Shield*
ESD
FDSOI
FET* Field effect transistor*
Fin FET
Floating gate memor*
Fluxtronic*
Gallium nitride electronic*
Gallium phosphide
Gate oxide*
Giant magnetoresistance
Giant magneto-resistance
GMR
GOI Germanium-on-insulator
Graphene
III-V
Indium gallium arsenide
Integrated circuit*
Interconnect
Low K dielectric coating*
Magnetic memor*
Magnetic tunnel junction*
Magnetoresistive RAM
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Notes:
1. The word ‘graphene’ had to be omitted from the search for publications as it resulted in many
false positives.
2. The words electro-optical, graphene, III-V, iii-v, MoS2, MoSe2, nanoresonator*, nano-
resonator*, PMC*, nanomechanical system* and nano-mechanical system* had to be omitted
from the search for patents as they resulted in many false positives.
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ANNEX 3: ABBREVIATIONS
Abbreviation Definition
BEUC Bureau Européen des Unions de Consommateurs
CAGR Compound Annual Growth Rate
CBRAM Conductive Bridge Random Access Memory
CBRNE Chemical, Biological, Radiological, Nuclear and Explosive
CEN European Standardisation Committee
CMC Chemistry, Manufacturing and Controls
CMOS Complementary Metal-oxide Semiconductor
CNT Carbon Nanotubes
COD Co-decision Procedure
DFG Deutsche Forschungsgemeinschaft
d-MRI Diffusion Magnetic Resonance Imaging
DRAM Dynamic Random-Access Memory
EC European Commission
EEB European Environmental Bureau
EFSA European Food Safety Authority
EGE European Group on Ethics Roundtables
EoL End of Life
EPA Environmental Protection Agency
EPR Enhanced Permeation and Retention
ESD Electrostatic Discharge
ETUC European Trade Union Confederation
EU European Union
Eurofound European Foundation for the Improvement of Living and Working Conditions
FDSOI Fully-depleted Silicon on Insulator
FET Field Effect Transistor
f-MRI Functional Magnetic Resonance
FP7 Seventh European Framework Programme
GMR Giant Magnetoresistance
GOI Germanium-on-insulator
ICT Information and Communication Technologies
IPC International Patent Classification
IPR Intellectual Property Rights
ISO International Organisation for Standardisation
JRC Joint Research Centre
MAPP Manual of Policies and Procedures
MEMS Micro-electromechanical System
MNBS Micro- and Nano-Bio Systems
MOSFET Metal Oxide Semiconductor field-effect transistor
MR Magnetic Resonance
MRAM Magnetoresistive Random Access Memory
MRI Magnetic resonance imaging
MRS (MRSI) Magnetic Resonance Spectroscopy (imaging)
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Abbreviation Definition
MWCNT Multi-walled Carbon Nanotubes
MX2 Metal Dichalcogenides
NACE Nomenclature Statistique des Activites Economiques dans la Communauté
Européenne
NEMS Nano-Electromechanical System
NGO Non-Governmental Organisation
NIR Near Infrared
NIR-II Near-Infrared-ii Imaging
NOC Network on Chip
NOMS Nano-Optomechanical System
NP Nanoparticles
NST Nanoscience and Nanotechnology
NT Nanotechnology
OFET* Organic Field Effect Transistor
OLED Organic Light-Emitting Diode
OSHA European Agency for Safety and Health at Work
OSH-professional Occupational Safety and Health Professional
PATSTAT European Patent Office Worldwide Patent Statistical Database
PMC Programmable Metallisation Cell
ppm Parts Per Million
QD Quantum Dot
R&D Research and Development
REACH Registration, Evaluation, Authorisation and Restriction of Chemicals
RRAM Resistive RAM
SME Small or Medium Sized Enterprise
SNAP Strategic Nanotechnology Action Plan
SOI Silicon-On-Insulator
SRAM Static Random Access Memory
STOA Science and Technology Options Assessment
STT MRAM Spin Transfer Torque Magneto-Resistive Random Access Memory
STT RAM Spin Transfer Torque Random Access Memory
SWCNT Single Walled Carbon Nanotubes
TMDC Transition Metal Dichalcogenide
TT Technology Transfer
US United States
US EPA US Environmental Protection Agency
US NIOSH US National Institute for Occupational Safety and Health
USA United States of America
UV/Vis/IR Ultraviolet / Visible / Infra-red
VC Venture Capital
WEEE Waste Electrical and Electronic Equipment
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ANNEX 4: TERMINOLOGY
Word/phrase Definition/explanation
Carbon Nanotubes Allotropes of carbon with a cylindrical nanostructure.
Dendrimers Nanostructured synthetic molecules having evenly spread branching
structure originating out of a central core.
Liposomes An artificially-prepared vesicle composed of a lipid bilayer
Nanobiosensors Biosensor at nano-scale: measurement system for detection of an analyte
that combines a biological component with a physiochemical detector
Nano-biotechnology Intersection of nanotechnology and biology, the ways that nanotechnology
is used to create devices to study biological systems, this is different from
bionanotechnology
Nanocapsule Nano-scale shells made of non-toxic polymer
Nanocarrier Nano-object or objects, which are at a larger scale but which carry
nanoscale payloads able to transport a diagnostic or therapeutic agent
either on its surface, within its bulk structure or within an internal cavity
Nano-coatings Applying a coating of nano-scale structures to a surface.
Nanocrystal Nano-object with a crystalline structure
Nanodiagnostics Application of nanotechnology in molecular diagnostics
Nanoemulsion Nanodispersion with a liquid matrix and at least one or more liquid nano-
objects
Nano-enabled Products, systems, devices integrating, using, enabled by nanotechnology
Nano-fibres Nano-object with two external dimensions in the nanoscale and the third
dimension significantly larger
Nano-indentation Variety of indentation hardness tests applied to small volumes. For testing
the mechanical properties of materials (hardness).
Nanomaterials Materials the single units of which is sized (in at least one dimension)
between 1 and 1000 nanometres (10^−9 meter) but is usually 1—100 nm
(the usual definition of nano-scale).
Nanomedicine Medical application of nanotechnology
Nanometres One billionth of a metre
Nano-needles Conical or tubular needles in the nanometre size range, made from silicon
or boron-nitride with a central bore of sufficient size to allow the passage
of large molecules
Nanoparticle Small object that behaves as a whole unit with respect to its transport and
properties, between 1 and 100 nanometres in size.
Nanopolymers Nanostructured polymers
Nanoproducts Any product containing nanoparticles
Nanorod One morphology of nano-scale objects, produced by direct chemical
synthesis.
Nano-scale Refers to structures with a length scale applicable to nanotechnology,
usually cited as 1–100 nanometres, also called nanoscopic scale
Nanoscience The study of the fundamental and functional properties of matter on the
nano-scale.
Nanosensor Any biological, chemical, or surgical sensory points used to convey
(proteomic, gold) information about nanoparticles to the macroscopic world
Nanoshells (plasmon) This is also called nanoshell plasmon, is a type of spherical nanoparticle
consisting of a dielectric core, which is covered by a thin metallic shell
(usually gold).
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Word/phrase Definition/explanation
Nano-specific Refers to a system or response that is sensitive to nanomaterials
Nanostructures An object of intermediate size between microscopic and molecular
structures
Nanosuspensions Submicron colloidal dispersions of nanosized drug particles stabilised by
surfactants. Nanosuspensions consist of the poorly water-soluble drug
without any matrix material suspended in dispersion
Nanotechnologies / Manipulation of matter with at least one dimension sized from 1 to 100
Nanotechnology nanometres
Nanotechnology-Based Suite of technologies using nanomaterials, structures and objects
Platforms
Nanotube Hollow nano-fibre
Quantum Dots A nanocrystal made of semiconductor materials that are small enough to
exhibit quantum mechanical properties
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AUSTRIA
In Austria, the two main ministries involved in the funding of research and development (R&D) are
the Federal Ministry of Science and Research (BMWF)528 and the Federal Ministry for Transport,
Innovation and Technology (BMVIT)529. The largest share of direct support for R&D is channelled
through three funding agencies: The Austrian Science Fund (FWF)530 that focuses on funding
academic research; the Austrian Research Promotion Agency (FFG)531 specialising in funding applied
industrial research and the co-operation between the higher educational sector and industry; and
the Austria Economic Service (AWS)532 that is mainly active in support programmes for SMEs.
In 2004, the Federal Ministry for Transport, Innovation and Technology launched the “Austrian NANO
Initiative” and in 2010, the “Austrian Nanotechnology Action Plan”533 was adopted by the
Federal Government. The NANO initiative was a response to regional activities in the Austrian
Bundesländer (such as NanoNet Styria [for more information, see later in this Annex]) that sought
to identify existing competences and to formulate potential themes for large-scale co-operative
projects.
An important motivation in the establishment of such a national research programme was the
expectation that its creation would strengthen the national research community in specific fields
thereby better linking them to international communities. At that time, most Austrian peer countries
(Germany, Switzerland, UK, and Finland), as well as the European Framework Programmes, were
using the label nanotechnology for framing focused research programmes.
The NANO initiative aimed to address the following issues: What would be the best way for Austria
to harness the opportunities in nanotechnology (for instance, in environmental and energy
technology and new resource-saving products or for small- or medium-sized enterprises)? How could
Austria contribute to ensuring the safety for its citizens of nanotechnology applications?
NANO had the following objectives: to increase networking among actors to achieve critical mass;
to open up ways to exploit the benefits of nanotechnology for industry and society; and to ensure
proper support for qualified personnel. To achieve these objectives, it had two programme action
lines:
1. National co-operative RTD Projects (Research and Technology Development in Project
Clusters (RPCs) and
2. Transnational co-operative RTD Projects (Research and Technology Development in
Transnational Projects).
527
https://rio.jrc.ec.europa.eu/
528
http://www.en.bmwfw.gv.at/
529
https://www.bmvit.gv.at/en/
530
https://www.fwf.ac.at/en/
531
https://www.ffg.at/en
532
http://www.awsg.at/
533
https://www.bmlfuw.gv.at/dam/jcr:00058164-0320-4544-b6a4-
320325dcfd86/Austrian%20Nanotechnology%20Action%20Plan.pdf
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A key aspect of the Nanotechnology Action Plan to implement the NANO initiative was to
strengthen communication and the dissemination of information to specific target groups,
particularly the interested public. Information on the fundamentals, opportunities and risks of
nanotechnology was provided to the public through an information portal for nanotechnology. A
primary objective was to engage the public in the process of drawing up and implementing a
Nanotechnology Action Plan534, which underwent public consultation via the Internet in Autumn
2009, as did the Implementation Report in November 2012. The feedback received was published
online and taken into account in the follow up to the Action Plan and Implementation Plan
respectively.
One of the central measures of the Austrian Nanotechnology Action Plan was the establishment of a
programme for the environment, health and safety (EHS). NANO EHS was established to provide
targeted funding for environment- and health-related research into assessing the risks of synthetic
nanomaterials.
NANO was implemented from 2004 to 2011 by the Austrian Research Promotion Agency (FFG)535
and, in total, nine large-scale co-operative projects were funded across a wide array of sectors such
as photonics, nanomedicine, and nanomaterials. Since 2012, support for nanotechnology R&D has
been provided through the thematic programmes of FFG.
In addition to the above governmental actions, an Austrian network was created, BioNanoNet536,
combining a wide range of expertise in numerous disciplines of medical and pharmaceutical research
in nanomedicine and nanotoxicology. The BioNanoNet Association is also the owner of BioNanoNet
Forschungs GmbH. Working across both biotechnology and nanotechnology, and visible at
international levels, BioNanoNet addresses the scientific areas of:
• Nanotoxicology,
• Sensor technology
• Health and safety, including (nano-) medicine and nanosafety.
The BioNanoNet coordinates EURO-NanoTOX537, which is an open virtual centre and national
platform. EURO-NanoTOX is co-funded by the Federal Ministry of Science and Research (BMWF). It
elaborates strategies to conduct standardised toxicological in-vitro as well as in-vivo methods on
nanostructured materials. Its main focus is on human nanotoxicology and human risk assessment.
Regional Nanotechnology initiatives:
Wirtschaftsstrategie Steiermark 2020 (2011) 538: Styria's Economic Strategy 2020 is a
successor to the State Government's previous economic strategy 2006. The 2006 strategy identified
so-called economic and technological strong-points (“Stärkefelder”) of the region, on which
innovation policy activities were focused: material sciences; mechanical engineering/automotive and
transport technologies; chemical and process engineering; human technology; information and
communication technologies; environmental technologies; energy; building services engineering
(including timber construction); nanotechnology; computer simulation and mathematical modelling.
The 2011 strategy bundles activities in these fields under three major leading themes: i) mobility,
ii) eco-technology, and iii) health technology. The central aim is to focus on future activities and to
establish Styria as a “European benchmark for the structural change towards a knowledge based
production-society”.
BELGIUM
Since its two regions play a central role in Belgian policy making, the main nanotechnology activity
in the country is carried by the regional government of Flanders, with a number of institutions
working in the area of nanotechnology.
534
http://www.sozialministerium.at/cms/site/attachments/6/1/7/CH2120/CMS1371046721712/umsetzungsb
ericht_2012_en.pdf
535
https://www.ffg.at/en
536
http://www.bionanonet.at/about-bionanonet
537
http://www.bionanonet.at/about-nanotoxicology?lang=english
538
http://www.wirtschaft.steiermark.at/cms/beitrag/10430090/12858597
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539
http://www.ewi-vlaanderen.be/wat-doet-ewi/excellerend-onderzoek/strategische-onderzoekscentra
540
http://www2.imec.be/be_en/home.html
541
http://www.vib.be/en/Pages/default.aspx
542
https://vito.be/en
543
https://www.iminds.be/en
544
www.nano.be/
545
http://www.csnmt.cz/getfile.php?type=file&IDfile=24
546
http://www.vyzkum.cz/FrontClanek.aspx?idsekce=1020
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DENMARK
In Denmark, the Ministry of Higher Education and Science547 has the main responsibility for research
and innovation policy.
In the period from 2001 to 2004, steering groups set up by the Danish government carried out a
Technology Foresight pilot programme. The aim of the programme was to carry out eight foresight
studies in the three-year period, and to identify issues of strategic importance for science,
technology, education, regulation and innovation policy in these areas. The foresight studies included
bio- and health care technologies, and ICT (pervasive computing, future green technologies, hygiene
and nanotechnology, especially nanomedicine548). The last phase of the foresight programme was
closely linked to the establishment of the Danish National Advanced Technology Foundation549 for
the development of generic technologies of future importance such as ICT, biotechnology and
nanotechnology.
The Action Plan “Strategy for Public-Private Partnership on Innovation”, launched in 2003, focused
on how to improve co-operation between education, research and trade/ business. The goal was for
more enterprises, especially SMEs, to have faster and easier access to knowledge. In 2004, the
Ministry of Science, Technology and innovation issued the Technology Foresight on Danish
Nanoscience and Nanotechnology – Action Plan550 as a basis for Danish policy on research,
education and innovation in the area. The vision was to raise awareness of and promote the
utilisation of nanotechnology in Denmark.
In 2003, on foot of the above developments, the Ministry of Science, Technology and innovation
published a call for the establishment of high-tech public-private networks in bio, nano and
information technology. The goal was to create stable collaboration patterns between companies
and knowledge institutions to increase knowledge transfer to, and use in, private industry. The
funding was to be used to finance networking. In the first round (in 2004) the Ministry provided
seven networks with a budget of EUR 3.7 million (around EUR 0.5 million each). Amongst the
networks was NaNet which, (together with Nano Øresund) became one of the two most important
Danish nanotechnology networks. NaNet's mission was to create platforms for the exchange of
information on nanotechnology, and to facilitate its utilisation on all levels of society, from research
and education to industrial application and development.
Between 2005 and 2010, EUR 116 million was allocated to strategic research centres, research
alliances and research projects, EUR 62 million being for nanotechnology, biotechnology and ICT.
Among the strategic research centres funded under the programme is a Centre for Nano-vaccines551.
Since 2009, the Danish National Advanced Technology Foundation has channelled funding for
projects in high-tech sectors, such as nanotechnology, biotechnology and ICT.
Support for nanotechnology research has been managed through a number of sources. The Danish
Council for Strategic Research, part of the Danish Agency for Science, Technology and Innovation is
one of these, although the council itself did not authorise funds for research, dependent instead on
the Programme Commission, which covers Nanoscience, Biotechnology and IT (NABIIT). The
Strategic Research Programme for the Interdisciplinary Applications of NABIIT technologies
supported the establishment of networks and research initiatives. Research support also came from
the Danish National Research Foundation, the Danish Ministry of the Interior and Health’s inter-
ministerial working group on Nanotechnology and Human Health, and the Danish National Advanced
Technology Foundation. Latterly, also under the Danish Council for Strategic Research, the
Programme Commission on Strategic Growth Technologies has had annual calls of total annual value
approximately EUR 10 million for research projects on nanotechnology, biotechnology and
information- and communication technology. In 2013, The Danish government and five political
parties decided to revise the research and innovation system, agreeing to merge the Danish National
Advanced Technology Foundation, the Danish Council for Strategic Research and the Danish Council
for Technology and Innovation into a new innovation foundation. Thus, the new organisation
547
http://ufm.dk/en
548
Danish Nano-science and Nano-technology for 2025, Foresight Brief No. 032
549
http://www.tekno.dk/about-dbt-foundation/?lang=en
550
http://ufm.dk/en/publications/2004/technology-foresight-on-danish-nanoscience-and-nanotechnology
551
http://www.nano-vaccine.org/
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Innovation Fund Denmark552 (IFD), has been the responsible body since 2014.
FINLAND
The main focus areas of public research and development (R&D) funding in Finland are energy and
the environment, health and well-being, the information and communications industry, the forest
cluster, and metal products and mechanical engineering. Nanotechnology is treated as a technology
to be applied across all these focus areas. Finland spends approximately 3.5 % of its gross national
product on (R&D). Exploitation of research results being seen as even more important than the
amount of investment, the Finnish innovation environment seeks to promote the exploitation of
scientific and technological results in Finnish companies.
The main research policy decisions are drawn up in the Science and Technology Policy Council of
Finland chaired by the Prime Minister. The principle instruments in the implementation of the policy
are the funding organisations working under the ministries. Tekes, the Finnish Funding Agency for
Technology and Innovation operates under the remit of the Ministry of Trade and Industry while the
Academy of Finland is governed by the Ministry of Education. Nearly 80% of all public research
funding is channelled through these two organisations.
The first Finnish nanotechnology programme was financed jointly by Tekes and the Academy
of Finland in 1997–1999553. Its objective was to build know-how, multi-disciplinary infrastructure
and linkages between fundamental and applied research. The programme also established a new
form of co-operation using joint funding between Tekes and the Academy of Finland. The total value
of the programme was EUR 7 million (Tekes EUR 4m, the Academy of Finland EUR 3 m).
FinNano, the Finnish nanoscience and nanotechnology programme, was established in 2005. The
programme was co-ordinated jointly by Tekes and the Academy of Finland and covered the whole
innovation chain from basic research to commercial products. The aim of the programme was to
strengthen Finnish nanotechnology research in selected focus areas and to accelerate the
commercial development of nanotechnology in Finland. The key objective was to boost
internationally recognised high-level research and competitive business based on nanotechnology.
In addition to FinNano, the Ministry of Education provided funding to develop nanoscience education
and infrastructure in Finnish universities and the Nanotechnology Cluster Programme was initiated
in 2007 with the Centre of Expertise Programme. In total, Finnish public funding for nanotechnology
during 2005–2010 was approximately EUR 235m.
In practice, the FinNano programme was executed in two parts: Tekes’ FinNano – Nanotechnology
Programme (2005–2009) and the Academy of Finland’s FinNano – Nanoscience Programme (2006–
2010). The Programme had a total value of approximately EUR 70m, including EUR 25m in research
funding and EUR 20m in corporate financing from Tekes. The original programme plan defined three
main focus areas:
1) Innovative nanostructure materials;
2) Nanosensors and nanoactuators; and
3) New nanoelectronics solutions.
In 2007, the aims of the programme were redefined as being for:
• Society: Renewal of industry clusters and production, environment and safety;
• Applications: Electronics, forest cluster, chemical sector, health and well-being; and
• Technologies: Nanostructured and functional materials, coatings and devices; Measurement
methods, production and scalability.
According to a programme’s interim evaluation in 2008, the main successes of FinNano were to
activate companies in research and product development, to map all the existing nanotechnology
infrastructure and to create cross-cutting networks of nanotechnology professionals.
In 2011, the final report on FinNano was published, showing the results of the Programme554.
552
http://innovationsfonden.dk/en; In 2015, IFD had an annual budget of DKK 1.6 billion, but their budget is
expected to decrease to DKK 1.47 billion in 2016. The total budget for innovation funds areas was over DKK 2
billion in 2010, so a significant loss of funding took place during the last 5 years.
http://innovationsfonden.dk/da/nyhed/innovationsfonden-investerer-ogsaa-i-forskernes-gode-ideer
553
http://www.tekes.fi/globalassets/julkaisut/research_and_technology.pdf
554
http://www.tekes.fi/globalassets/julkaisut/finnano_loppuraportti.pdf
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According to that report and an independent evaluation by Gaia Consulting Ltd., all the Finnish
nanotechnology programmes succeeded and fulfilled their objectives, which ranged from capturing
knowledge in nanoscience and technology to boosting Finnish nano research and business. The next
steps in the development of nanotechnology for industry in Finland were recommended to be
achieved by other means. These included measures to enhance technology transfer, encouragement
of entrepreneurship, and seed funding and basic research funding based on problems and not in
disciplines.
In more recent years, Finland has therefore stopped identifying nanotechnology as a separate area
for funding, opting to fund it under general R&D funding programmes and actions to enhance
technology transfer and commercialisation by industry in Finland.
FRANCE
In 1999, the “French Research Network in Micro and Nano Technologies” (RMNT) was created
for the purpose of strengthening and reorganising micro- and nano research and aligning it with the
private sector.
In 2003, a network of major technology centres was created, linking together the facilities at
the following organisations:
The creation of this network was supported by a total subsidy of EUR 100 million for the period 2003
to 2006.
Launched in 2003 to fund fundamental research, France’s national Nanosciences Programme was
co-ordinated by the Ministry of Research in co-operation with the CNRS (National Scientific Research
Centre), the CEA (French Atomic Energy Commission) and the DGA (General Delegation for
Weaponry).
In 2005, the French National Research Agency (ANR) was established to assume responsibility for
the funding and organisation of all national R&D projects, in order to improve co-ordination. Today,
national nano research is funded within the national programme for nanosciences and
nanotechnologies (PNANO560) under the ANR. The budget of the ANR for 2005 was EUR 539m, EUR
35.3m of which was dedicated to PNANO. The ANR has funded research projects in nanosciences
and nanotechnologies mostly through the following research programmes:
• Non-thematic programmes (called “programmes blancs”)
• Nanotechnologies and Nanosystems programmes P2N.
• Additional programmes, which are more specific to a given topic, such as those on hydrogen
storage and fuel cells or on home photovoltaics.
A EUR 35 billion economic stimulus package Investissements d’Avenir561 (Investments for the
Future) was launched at the end of 2009. Within that context and since 2011, nano-bio-technology
has been one of the priority areas for funding under the ANR, with a particular focus on health and
environmental research. The package aims to support scientific research, accelerate its transfer to
a pilot stage and to consolidate knowledge about toxicology and nanomaterials, the programme is
funding therapies, imaging, diagnostics and medical devices base on nanotechnology and
biotechnology.
555
http://www-leti.cea.fr/en/
556
https://www.laas.fr/public/
557
http://www.lpn.cnrs.fr/fr/Commun/
558
http://www.ief.u-psud.fr/
559
http://exploit.iemn.univ-lille1.fr/
560
http://www.agence-nationale-recherche.fr/suivi-bilan/historique-des-appels-a-projets/appel-
detail1/programme-national-en-nanosciences-et-nanotechnologies-pnano-2005/
561
http://www.gouvernement.fr/investissements-d-avenir-cgi
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GERMANY
As far back as 1998, the Federal Ministry of Education and Research (BMBF) increased collaborative
project funding for nanotechnology. In addition, an infrastructure plan was put in place in the form
of the establishment of six competence centre networks. The measures were implemented two years
before the USA began its national nanotechnology initiative and four years before the European
Union’s comparable measures under the Sixth Framework Programme.
In 2004, the German Innovation Initiative for Nanotechnology - “Nanotechnology Conquers
Markets562” was launched and presented to the public. On the basis of the White Paper presented
at the nanoDe congress in 2002 and intensive discussions with representatives from business and
science, the BMBF’s new approach to nanotechnology funding was based on Germany’s highly-
developed and globally competitive basic research in sciences and technology and primarily aimed
to open up the application potential of nanotechnology through research collaborations (leading-
edge innovations) that strategically target the value-added chain. The main elements of the strategy
were to open up potential markets and boost employment prospects in the field of nanotechnology.
Five leading-edge innovation programmes were funded initially:
• NanoMobil, for the automotive sector;
• NanoLux, for the optics industry;
• NanoforLife, for pharmaceuticals and medical technology;
• NanoFab, for electronics; and
• NanoChance, a BMBF funding measure for targeted support of R&D -intensive small and
medium-sized enterprises.
Existing policy actions were re-organised under the umbrella of the High-Tech Strategy563 in 2006.
This was done through the Nano Initiative—Action Plan 2010564, a cross-departmental initiative
by seven departments of the Federal Government that started in 2007 and was headed by the BMBF.
Tying in with BMBF's 2004 Innovation Initiative for Nanotechnology, the action plan aimed to
integrate nanotechnology funding in the various policy fields into a national nanotechnology strategy.
The Action Plan's main goals were (1) to speed up the use of the results of nanotechnological
research for innovations; (2) to introduce nanotechnology to more sectors and companies; (3) to
eliminate obstacles to innovation by means of early consultation in all policy areas; and (4) to enable
an intensive dialogue with the public. The focus was on the opportunities offered by nanotechnology,
but possible risks were also taken into account. The total funding for the years 2007 to 2009 was
EUR 640 million.
In 2011, the German Ministry for Education and Research (BMBF) published the Action Plan
Nanotechnology 2015565, outlining the strategy for responsible development, innovation and
public dialogue for the period 2010-2015. The plan included proposals for developing nanotechnology
in five main areas (climate/energy, health/food and agriculture, mobility, communication and
security). In parallel, a new funding instrument was launched - Innovation Alliances - to provide
funding for strategic co-operation between industry and public research in key technology areas that
demand a large amount of resources and a long time horizon, but promise considerable innovation
and economic impacts. Public funds and funding from the industry is combined in a typical proportion
of 1:5 (public: private). Innovation was supported with special emphasis on SMEs and development
of value chains. Risk assessment was incorporated as well as an improvement of boundary conditions
such as educating the workforce, and addressing issues of legislation, norms and standards. The
public dialogue on nanotechnology was intensified, including information and dialogue with citizens
as well as stakeholders and NGOs.
Innovation alliances were launched as a successor to the leading edge innovation programmes. They
were planned as an instrument of public support to ground-breaking industrial innovation, providing
support funding for strategic co-operation between industry and public research in high-potential
technology areas that require high levels of funding and long lead times. Through a public-private
partnership, the Federal Government provided funding for R&D and other innovation-related
562
http://d-nb.info/97392179x/34
563
http://www.research-in-germany.org/en/research-landscape/r-and-d-policy-framework/high-tech-
strategy.html
564
http://www.cleaner-production.de/fileadmin/assets/pdfs/Nano_initiative_action_plan_2010.pdf
565
http://www.lai.fu-berlin.de/homepages/nitsch/publikationen/Germany_ActionPlanNanotechnology_2015.pdf
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activities for specific, long-term co-operative R&D projects. R&D activities could range from
fundamental research to prototype development. Public funds were complemented by private money
from industry, typically at a proportion of 1:5 (public: private). Each innovation alliance was set up
through an industry initiative, organised as a long-term co-operative research project and involving
several industry partners as well as public research organisations.
An Innovation Alliance that followed this policy approach was on “Molecular Imaging for Medical
Engineering” (nanotechnology) and was formed by Bayer Schering Pharma AG, Boehringer
Ingelheim Pharma GmbH & Co. KG, Carl Zeiss AG, Karl Storz & GmbH Co. KG and Siemens AG. The
alliance’s goal was creating new diagnostic agents and imaging procedures for clinics and the
development of pharmaceuticals.
In addition to policies and programmes to support R&D and commercialisation, Germany took action
to address concerns about the environmental and safety costs of the nanotechnology. These are
particularly important to look at when trying to develop and label commercial nanotechnology
products for the market. In response to these issues, governments have increasingly included the
concept of responsible development in their nanotechnology activities. Responsible development
aims to stimulate the growth of nanotechnology applications in diverse sectors of the economy, while
addressing the potential risks and the ethical and societal challenges the technology might raise.
Germany has dedicated policies for the responsible development of nanotechnology. The report
“Responsible Handling of Nanotechnologies” (“Verantwortlicher Umgang mit Nanotechnologien”)
launched by the Nano-Commission of the German Federal Government in December 2010 showed
that the nanotechnology sector is continuing to develop dynamically.
Regional initiatives in Germany that make specific mention of nanotechnology include:
• Innovation Strategy of Nordrhein-Westfalen (2006): This strategy was a government
statement dated 26 June 2006. It presented a short analysis of the importance of innovations
for North Rhine-Westphalia, and in the following elaborated the overall strategy and the
measures employed and purposes targeted. The government strategy aimed to generate new
potential for growth by reinforcing strengths, sharpening profiles, promoting excellence and
pooling forces. Thus, the funding of research and technology was focused on four priority areas
with high potential both related to innovation, employment and growth: (i) nanotechnology,
microtechnology and new materials; (ii) biotechnology; (iii) energy- and environmental
research; and (iv) medical research, medical engineering.
• Cluster Offensive Bayern (2007)566: The Bavarian cluster policy was initialised in 2007 and
focused on 19 branches/technologies with high importance for the future of Bavaria. These
were organised into five fields:
- materials engineering (including nanotechnologies, materials engineering, chemical
industries);
- mobility (including automotive, rail, logistics, aerospace and satellite navigation);
- life sciences and environment (including biotechnology, medical technologies, energy
technologies, environmental technologies, forestry and food);
- IT and electronics (ICT, high-performance electronics, mechatronics and automation); and
- service and media (financial services, media).
After a positive evaluation in 2010, the State Government announced some changes in the future
organisation of the overall initiative: A major change is that the (nonetheless successful) clusters
high-performance electronics, logistics, biotechnology and medical technologies would be
restructured into networks, while future funding would be focused on the other clusters, where
funding so far was most successful in generating additionality.
• Research Strategy of Thuringia (2008): Main objectives of Thuringia's research policy were to
strengthen regional universities and non-university research institutes and regional companies
in their research and development efforts to achieve scientific excellence, to initiate knowledge
and technology transfer as well as innovation. The document described outstanding research
areas of the state and measures to strengthen and relate the regional research landscape to
target fields in the regional economy: micro and nano technologies, microelectronics;
information and communication technologies; media and communication; health research and
medical technology; microbiology and biotechnology; optical technologies, photonics;
566
https://www.cluster-bayern.de/en/
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IRELAND
Following the establishment of Science Foundation Ireland (SFI) in 2000, public funding was made
available to support many public research initiatives including the Centre for Research on
Adaptive Nanostructures and Nanodevices (CRANN)567. Since its foundation in 2003, CRANN
has become a research institute of international standing with 17 Principal Investigators (PIs) across
multiple disciplines including physics, chemistry, medicine, engineering and pharmacology, and a
total of 250 researchers. CRANN was funded predominately by Science Foundation Ireland (SFI), in
partnership with two universities (Trinity College Dublin and University College Cork) and industry,
and was formed to harness the cross-disciplinary nanoscience research of individual PIs to deliver
world leading research outputs and to enable CRANN researchers to address key industry challenges.
In addition, in December 2009, the Competence Centre in Applied Nanotechnology (CCAN)
was launched. It was an industry-led, collaborative, applied research centre enabling its member
companies and research providers to work together to develop nanotechnology enabled products
and solutions for the ICT and biomedical industries (i.e. diagnostics, drug delivery, and regenerative
medicine). It was co-hosted by CRANN and Tyndall National Institute at University College Cork.
With a growing membership, the founding industry members were Aerogen, Analog Devices, Audit
Diagnostics, Creganna-Tactx, Intel, Medtronic, Proxy Biomedical and Seagate. CCAN ran until mid-
2015.
Ireland has developed its reputation in nanoscience with its researchers recently ranked sixth
globally for the quality of their research. Active collaborations between industry and academia exists
and are beginning to deliver significant economic benefits to Ireland. Three of the largest industries
in Ireland are directly impacted by nanoscience research in perhaps – medical devices,
pharmaceuticals and ICT.
The industry ministry, the Department for Jobs, Enterprise and Innovation (formerly the Department
of Enterprise, Trade and Employment) plays a pivotal role in industrial innovation policy with its
agencies, Enterprise Ireland (EI) (responsible for supporting Irish companies); Science Foundation
Ireland (SFI) (funding basic and applied research); and IDA Ireland (in charge of overseas inward
investments).
Apart from the establishment of research infrastructures, policy priorities were also being addressed
in the Irish national innovation system. In 2004, the Irish Council for Science, Technology and
Innovation, with its Secretariat provided by Forfás, launched its ICSTI Statement on
Nanotechnology. The Statement assessed Ireland's capabilities in the field of nanotechnology,
mapped out specific areas of opportunity for the Irish economy and presented a sustainable vision
and strategy for the promotion, development and commercialisation of nanotechnology in Ireland.
Among the key application areas that were identified were also pharmaceutical and medical
technologies.
In 2010, Forfás568 itself launched a report on 'Ireland's Nanotechnology Commercialisation
Framework 2010 – 2014’. The report presented a national framework to position Ireland as a
knowledge and innovation centre for certain niche areas of nanotechnology. It highlighted that
Ireland’s nanotechnology players should focus on three main technology areas (advanced materials,
“More than Moore” and nanobiotechnology) and four application areas (next generation electronics,
medical devices & diagnostics, environmental applications, and industrial process improvements).
The BioNano Laboratory in CRANN (mentioned above) is dedicated to interdisciplinary research at
the interface between the physical and life sciences including nanotechnology and diagnostics,
nanotoxicology and nanomedicine. The group investigates molecular, cellular and physiological
interactions using novel biophysical tools such as cell actuators, and magnetic and ultrasound fields.
Members of the BioNano Laboratory are also members of the Integrated Nanoscience Platform
http://www.crann.tcd.ie/
567
568
Forfás ceased to exist in 2015 and was, in part, subsumed under the Department of Jobs, Enterprise and
Innovation.
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for Ireland (INSPIRE)569, a consortium of all Irish third level institutions with international leading
research capability in nanoscience and nanotechnology. Furthermore, CRANN is also part of the
Molecular Medicine Institute which is a not for profit company established by an extended network
of Irish Universities and their associated academic hospitals. The BioNano Laboratory aims to
facilitate and accelerate the translation of biomedical nanotechnology research into improved
nanoscale diagnostics and nanomedicine.
In October 2013, a new Science Foundation Ireland funded research centre, Advanced Materials
and BioEngineering Research (AMBER)570 was launched. AMBER is jointly hosted in TCD by
CRANN and the Trinity Centre for BioEngineering, and works in collaboration with the Royal College
of Surgeons in Ireland and UCC. The centre provides a partnership between leading researchers in
material science and industry to develop new materials and devices for a range of sectors,
particularly the ICT, medical devices and industrial technology sectors.
THE NETHERLANDS
In the Netherlands, nanotechnology was established as a distinct field of scientific research in the
early years of the 21st century. A foresight study (Ten Wolde 1998) conducted by the Dutch Study
Centre for Technology Trends (STT) between 1996 and 1998 laid the foundation of a national
research agenda. The study showed the importance of nanotechnology for electronics, materials,
molecular engineering and instrumentation, and recommended to pay due attention to nanosafety
issues and set up research in that area.
The Netherlands hosts three dedicated nanotechnology research centres: The University of Twente
(with the Mesa+ research centre in microsystems technology and nanomaterials571), Delft University
of Technology (with the Else Kooi Laboratory572, previously called Dimes research centre on
nanoelectronics) and the University of Groningen (with BioMaDe573 focused on bio-
nanotechnology). The early 2000s, these formed the core of NanoNed - the Nanotechnology R&D
initiative in the Netherlands574. NanoNed was initiated after three years of preparatory work in 2004
by nine industrial and scientific partners including Philips and TNO. It clustered the Dutch expertise
on nanotechnology and enabling technology into a national network. The total budget of the
NanoNed programme amounted to EUR 235 million, funded by the Dutch Ministry for Economic
Affairs. The NanoNed programme was organised into eleven independent programmes or flagships.
Each of those was based on regional R&D strength and industrial relevance. The flagships were
Advanced NanoProbing, BioNanoSystems, Bottom-up Nano-Electronics, Chemistry and Physics of
Individual Molecules, Nano Electronic Materials, NanoFabrication, Nanofluidics,
NanoInstrumentation, NanoPhotonics, Nano-Spintronics and Quantum Computing.
In 2006, the Cabinet vision on Nanotechnology “From Small to Great” was published. The content
of the document mirrored the outline of the European Commission’s 2005 Action Plan, with sections
on business and research opportunities; societal, ethical, and legal issues; public engagement; and
risk assessment.
In 2008, the Dutch Government published its Nanotechnology Action Plan575. The plan, prepared
by the Interdepartmental Working Grou #p on Nanotechnology (ION) and building on the 2006 vision
document, incorporated the most up-to-date scientific findings, and reflected information and
agreements from European Union and other international initiatives. Four generic themes were
defined on the basis of the central theme impact on society and risk analysis, i.e.: bio-nano-
technology, beyond Moore, nanomaterials, and nano production (including instrumentation and
characterisation). In addition, four application areas were singled out: clean water, energy, food and
“nanomedicine”.
The Dutch systematic approach to nanotechnology strategy resulted in the development of stable
569
http://www.crann.tcd.ie/Research/Academic-Partners/testt.aspx
570
http://ambercentre.ie/
571
https://www.utwente.nl/mesaplus/
572
http://ekl.tudelft.nl/EKL/Home.php
573
http://www.biomade.nl/
574
However, four other universities, and TNO, the Netherlands Organisation for Applied Scientific Research, are
also represented.
575
http://www.rritrends.res-agora.eu/uploads/27/8079721-bijlage%281%29.pdf
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research groups, centres, department and laboratories. On the national level, NanoLab NL576
formed a consortium that built, maintained and provided a coherent and accessible infrastructure
for nanotechnology research. NanoLab drew on government funding, which was first spent on
upgrading existing infrastructure. Only when the existing infrastructure was fully used and a well-
characterised additional need was identified and additional investment made. As a consequence, the
Dutch nanotechnology research infrastructure was heavily used by research groups and the local
industry. The partners in this enterprise considered themselves often as competitors but co-operate
and co-ordinate their actions because of the substantial government funding.
In 2011, the NanoNextNL577 national research programme on nanotechnology was started as a
continuation of NanoNed and MicroNed (the Netherlands Microtechnology program). NanoNextNL is
based on a Strategic Research Agenda that was asked for by the government in both the cabinet
and the action plan. Risk evaluation and Technology Assessment form part of this research
programme. 15% of the budget is dedicated to risk-related research, as was demanded by
government in the action plan. It is planned that NanoNextNL programme will finish in 2016 but
anticipated that many aspects of it will be continued under an industry umbrella. Since 2011, the
research agenda for nanotechnology is also part of the Top sector policy of the Netherlands578,
which aims to enhance the knowledge economy by stimulating nine top sectors (leading economic
sectors).
The Top sector policy is implemented via innovation contracts, in which agreements are laid down
between business leaders, researchers and government, jointly focusing the available resources for
knowledge and innovation towards the leading economic sectors. Support programmes that aim to
support the development and deployment of nanotechnology, are mostly project based. The formats
for such supports range from small business oriented measures to financing large research project
which involve co-operation between private and public research performers.
POLAND
In 2000, the Polish State Committee for Scientific Research (KBN) started a targeted research project
in the topic of nanotechnology called “Metallic, Ceramic and Organic Nanomaterials:
Processing – Structure – Properties – Applications” with two aims:
• stimulating research on nanomaterials in Poland and promoting collaboration between
researchers in this field; and
• making a landscape of the status of nanotechnology in Poland.
The project involved 15 scientific institutions working on 26 research tasks.
In the Polish National Development Plan for the years 2007-2013, launched by the State Committee
for Scientific Research in Warsaw in 2004, nanotechnology was foreseen as an area that should
contribute to achieving a significant competitive potential in the European Arena.
During 2006, the Ministry of Science of Higher Education established the Interdisciplinary Committee
for Nanoscience and Nanotechnology. This Committee analysed the nanotechnology situation and
capabilities in Poland and proposed the basic fields that should be strategically supported and
launched in 2007 the “Strategy for the Reinforcement of Polish Research and Development
Area in the Field of Nanosciences and Nanotechnologies”579. The areas to be supported were
nanoscale phenomena and processes, nanostructures, nanomaterials and nanoscale devices on the
one side and nano-analytics/nano-metrology and manufacturing processes and devices for
nanotechnology on the other. The priority of the strategy of nanosciences and nanotechnologies was
the development, co-ordination and management of the national system of research, education and
industry in this field in the short-, medium-, and long-term perspective. Other main objectives to be
achieved by 2013 were the development of high added-value nanotechnology products, the creation
and commercialisation of manufacturing devices for the production of nanomaterials, the
development of the education system in the field of nanotechnology, educating about 20-30 doctors
yearly in the specialisation of nanotechnology, building specialist laboratories, establishing co-
operation networks of research and industrial units, financial institutions, etc. and integrating
576
http://www.nanolabnl.nl/
577
http://www.nanonextnl.nl/
578
http://topsectoren.nl/english
579
www.bioin.or.kr/fileDown.do?seq=5186
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PORTUGAL
In 2005, the Portuguese and Spanish Governments decided to jointly create the International
Nanotechnology Laboratory (INL)580 in Braga, Portugal, which was partly funded under the
European Regional Development Fund (ERDF). The decision of Portugal and Spain to create an
international research laboratory was announced by the head of Government of Spain and the Prime
Minister of Portugal at the end of the XXI Portugal-Spain Summit that took place in Évora, Portugal.
The International Nanotechnology Laboratory (INL) was installed in Braga, Portugal, its Director is
the Swedish Professor Lars Montelius, and it has over 90 employees.
INL concentrates on nanotechnology, and considers applications to several other areas, following a
truly interdisciplinary approach. The Laboratory has been conceived to:
• Assure world class research excellence in all areas of activity;
• Develop partnerships with the industry and foster the transfer of knowledge in economic
values and jobs;
• Train researchers and contribute to the development of a skilled workforce for the
nanotechnology industry; and
• Survey, prevent and mitigate nanotechnology risks.
Among its research areas nanomedicine, nanoelectronics, nanomachines & nanomanipulation and
environment monitoring, security and food quality control can be found.
Further information on the policies and programmes of Spain is given below.
SPAIN
The Minister of Economy and Competitiveness is responsible for the design of the national innovation
strategy in Spain. An Inter-ministerial Commission on Science and Technology (CICYT) has the role
of co-ordinating the actions of the different bodies involved in innovation policy in a complex
governance structure. The regions of Catalonia, the Basque Country and Valencia are especially
active in S&T policy.
The 2004-2007 R&D plan was the first Spanish national R&D plan containing a specific cross-
programme action regarding nanoscience and nanotechnology. The Strategic Action (SANSNT)
was designed for the overall enhancement of Spanish industry competitiveness through the
implementation of deep changes in several industrial sectors by generating new knowledge and
applications based on the convergence of new technologies, where nanotechnology plays a central
role. The SANSNT included seven thematic lines among which the first one is “Nanotechnologies
applied in materials and new materials within the field of health”. Also included are systems biology,
synthetic biology and nanobiotechnology. The Strategic Action encompassed the development of
activities within the six Instrumental Lines of Action (human resources; projects; institutional
strengthening; infrastructures; knowledge use; and articulation and internationalisation of the
system).
Nanoscience and nanotechnology were included as a Strategic Action of both the 2004-2007
National Plan for Research, Development and Innovation (R+D+I) and the funding set aside within
this Plan for the Industrial Sector (PROFIT Programme), with the aim of promoting the development
of industrial projects (carried out by companies) with nanotechnology-focused objectives.
During the 2004-2007 periods, around 40 projects were funded as a result of this Strategic Action,
receiving a total of EUR 2 million in subsidies and EUR 8.5 million in associated investments. All the
projects were coordinated by industrial companies, although universities and technological centres
were involved in the development of many of them either on a collaborative basis, or were
subcontracted by the company carrying out the project.
580
http://inl.int/
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In 2005, the Government of Spain launched the strategic programme INGENIO 2010581 to align
Spain with the strategy of the European Union to reach a 3% of the GDP invested in R&D by year
2010, thereby reducing the gap between Spain and other countries. Its general objective was to
achieve a gradual focus of Spanish resources on strategic actions to meet the challenges faced by
the Spanish Science and Technology System. This was to be achieved by continuing the existing
policies, agendas and successful programmes, as well as by implementing new actions needed to
finish meeting the challenges identified for the national science, technology and engineering system.
In order to enhance critical mass and research excellence, the goals of the INGENIO 2010
Programme, within the CONSOLIDER programme (launched by the Ministry of Education and
Science, through the General Secretariat of Scientific Policy, to promote high quality research and
to reach critical mass and research excellence), included creating Centros de Investigación
Biomédica en Red (Biomedical Research Networking Centres, CIBER) by setting up consortia, with
their own legal personality, without physical proximity, which were designed to conduct single-topic
research on a specific broadly-defined disease or health problem. CIBER were formed through the
association of research groups linked to the national health system to help form the scientific basis
of the programmes and policies of the national health system in the priorities areas of the National
R+D+I Plan. Among the centres that have been created within this programme is the Biomedical
Research Networking centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),
founded in 2006. The Nanobiomed consortium, which researches the use of nanoparticles for drug
delivery, was also founded with CONSOLIDER funds.
Between 2008 and 2011 the National Strategy of Nanoscience and nanotechnology, new
materials and new industrial products582 was implemented by the Ministry of Economy and
Competitiveness. This policy measure was part of the National Plan for R+D+I 2008-2011583 and its
objective was to enhance the competitiveness of Spanish industry by promoting knowledge about
and stimulating the development of new applications based on nanoscience, nanotechnology,
material science and technology, and process technologies. Six themes were targeted:
Nanotechnologies applied to materials and new materials in health sector, nanotechnologies for
information and telecommunications, nanotechnologies in relation to industry and climate, smart
materials with tailored properties based on knowledge as materials and performance coatings for
new products and processes, advances in technology and materials processing, development and
validation of new industrial models and strategies/new technologies for manufacturing design and
process/network production, and exploitation of convergent technologies. The measure covered
different lines such as supporting investments, projects, institutional strengthening, infrastructure
and utilisation of knowledge, supporting first market operations for innovative products and access
to early stage/development funding, system articulation and internationalisation and targeted public
research organisations, SMEs and other companies.
Both in the last Spanish Strategy of Science, Technology and Innovation 2013-2020584 and in the
State Plan of Scientific and Technical Research and Innovation 2013-2016585 (both dependent on
the Ministry of Economy and Competitiveness), nanotechnology is considered a sector to be boosted
when referring to Key Enabling Technologies (KETs), but there is not a strategic plan such as in
previous periods.
Regional initiatives in Spain include:
• Estrategia Nanobasque (2008)586: In order to promote the implementation of micro and
nanotechnologies in the Basque companies, the Basque Government designed a strategy called
NanoBasque in 2007. On December 3 2008, the Department of Industry, Trade and Tourism of
the Basque Government launched the nanoBasque Strategy in the framework of the Basque
Science, Technology and Innovation Plan 2010. The nanoBasque Strategy was an initiative
designed to develop a new economy sector enabled by nanotechnology. It was created with the
purpose of covering three main areas of action, namely: company, knowledge and society. One
581
http://www.ingenio2010.es/
582
http://www.idi.mineco.gob.es
583
Ibid
584
http://www.idi.mineco.gob.es/stfls/MICINN/Investigacion/FICHEROS/Spanish_Strategy_Science_Technology
.pdf
585
http://www.idi.mineco.gob.es/stfls/MICINN/Investigacion/FICHEROS/Spanish_RDTI_Plan_2013-2016.pdf
586
http://www.nanobasque.eu/aNBW/web/en/strategy/index.jsp
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of the objectives was to create a new model of relations to involve both national and international
companies, scientific, technological, political and social agent. The expected result were
targeting the efficiency and the integration of the ecosystem of innovation that was clearly aimed
at the market, based on the co-operation between all parties. The launch of the nanoBasque
Strategy was accompanied by the creation of a dynamic support agency, the nanoBasque
Agency, with the mission of coordinating and managing the development of the Strategy. The
nanoBasque Strategy strived to boost Basque the presence of companies and research agents
on international nanotechnology initiatives and markets. EUR 550 million were expected to be
mobilised in the 2009-2015 period, with a proportion of public funding of 52% on the total.
• Within the nanoBasque strategy and using CONSOLIDER funds, the Cooperative Research Center
NanoGUNE was created with the mission of performing world-class nanoscience research for the
competitive growth of the Basque Country, thereby combining basic research with the objective
of boosting nanotechnology-based market opportunities and contributing to the creation of an
enabling framework to remove existing barriers between the academic and business worlds.
• The Andalusian Centre for Nanomedicine and Biotechnology, BIONAND, is a mixed centre part
owned by the Regional Ministry of Health and Social Welfare, the Regional Ministry of Finance,
Innovation, Science and Employment and the University of Malaga. BIONAND has been co-
financed, with a contribution of 70% of the total cost, by the European Regional Development
Fund (ERDF) together with the Ministry of Economy and Competitiveness in the frame of The
Spanish National Plan for Scientific Research, Development and Technological Innovation 2008-
2011 (record number, IMBS10-1C-247, quantity. EUR 4.9m). The three main research areas are
nanodiagnostics, therapeutic nanosystems, and nanobiotechnology.
• IMDEA-Nanociencia is a private non-profit Foundation created by the regional Government of
the Community of Madrid in November 2006 to shorten the distance between the research and
society in the Madrid region and provide new capacity for research, technological development
and innovation in the field of nanoscience, nanotechnology and molecular design. Researchers
at IMDEA Nanoscience are developing distinct diagnostic tools, including nucleic acid-based and
nanoparticle-based sensors for detection of biological targets of medical interest, and magnetic
nanoparticles to be used in medical imaging as high-sensitive contrast agents.
587
https://www.gov.uk/government/organisations/innovate-uk
588
https://www.gov.uk/government/collections/sbri-the-small-business-research-initiative
589
http://webarchive.nationalarchives.gov.uk/20130221185318/http://www.innovateuk.org/_assets/pdf/taylor
%20report.pdf
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Micro/nano technologies were included within relevant broader collaborative R&D competitions,
principally in the materials, medicine and electronics areas. In 2007 the Nanotechnology
Knowledge Transfer Network (NanoKTN)590 was created with the objective of supporting the
exploitation and commercialisation of MNT through informing, linking and facilitating innovation and
collaborations between users and suppliers of nanotechnology in order to build a strong MNT
community in the UK. The centres were grouped into four main themes: nano-metrology;
nanomaterials (including health and safety); nanomedicine; and nanofabrication. Between its
creation and 2014 the NanoKTN secured about £82million for UK industry, mainly focussed on SMEs,
providing a good return investment on the initial input of £3million. In 2014, NanoKTN was merged
with another 15 KTN in the new organisation KTN Ltd.
In 2006, the Engineering and Physical Sciences Research Council issued its Report of the
Nanotechnology Strategy Group591 as an active response to the EPSRC 2005 Nanotechnology
Theme Day Report that found that there were flaws in the structure for nanotechnology R&D in the
UK. The report proposed, in conjunction with researchers and users, to identify a series of “grand
challenges” in nano-science and nano-engineering, focused initially on areas such as energy,
environmental remediation, the digital economy and healthcare, where an interdisciplinary, stage-
gate approach spanning basic research through to application will be an integral part of the challenge
of enabling nanotechnology to make an impact. The “grand challenges” were to be addressed via
interdisciplinary consortia spanning the EPSRC research spectrum, and including collaboration with
sister Research Councils (e.g. BBSRC).
In December 2007, the Research Councils announced a Cross-Council programme “Nanoscience
through Engineering to Application592”, with the objective of providing an additional GBP 50
million in areas where the UK nanotechnology research base could make a significant impact on
issues of societal importance such as healthcare. These societal or economic Grand Challenges
wanted to be addressed in a series of calls for large-scale integrated projects. They were led by the
Engineering and Physical Sciences Research Council, in collaboration with stakeholders including
other Research Councils, industry, the Technology Strategy Board (TSB) and the Nanotechnology
Research Coordination Group.
Government announced its intention to develop a UK Strategy for nanotechnologies in its 2009
response to the Royal Commission on Environmental Pollution’s report, Novel materials in the
Environment: The case of Nanotechnology.
The Nanoscale Technologies Strategy 2009-2012593 was launched in October 2009 by the TSB
and targeted the ways by which nanotechnologies could address major challenges facing society
such as environmental change, ageing and growing populations, and global means of communication
and information sharing. Its objective was to provide the framework for future applied research
predominantly through activity inspired by the needs of wider technologies and challenge-led calls.
In 2010, the Ministerial Group on Nanotechnologies, the Nanotechnology Research Co-ordination
Group (NRCG), and the Nanotechnology Issues Dialogue Group (NIDG) issued the UK
Nanotechnologies Strategy - Small Technologies, Great Opportunities594. This Strategy
defined how Government will take action to ensure that everyone in the UK could safely benefit from
the societal and economic opportunities that these technologies offer, whilst addressing the
challenges that they might present.
In 2012 the Department for Environment, Food and Rural Affairs (DEFRA) launched the
Nanotechnology Strategy Forum (NSF)595 to facilitate discussion and engagement between
Government and stakeholders in matters referred to the responsible advancement of the UK’s
nanotechnologies industries. The NSF is an advisory body formed by ad hoc expert with a
membership drawn from industry, regulators, academia and NGOs (non-governmental organisations
and it is jointly chaired by the Minister of State for Universities and Science (BIS) and the
590
https://connect.innovateuk.org/web/nanoktn
591
https://www.epsrc.ac.uk/newsevents/pubs/report-of-the-nanotechnology-strategy-group/
592
https://www.epsrc.ac.uk/newsevents/pubs/nanotechnology-programme/
593
http://www.nibec.ulster.ac.uk/uploads/documents/nanoscaletechnologiesstrategy.pdf
594
http://www.steptoe.com/assets/htmldocuments/UK_Nanotechnologies%20Strategy_Small%20Technologies
%20Great%20Opportunities_March%202010.pdf
595
https://www.gov.uk/government/groups/nanotechnology-strategy-forum
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Parliamentary Under-Secretary for DEFRA and is supported by a small secretariat based in DEFRA.
The UK Enabling Technologies Strategy 2012-2015596 also addresses four enabling technologies
- advanced materials; biosciences; electronics, sensors and photonics; and information and
communication technology (ICT) to support business in developing high-value products and services
in areas such as energy, food, healthcare, transport and the built environment. Nanotechnology is
identified as having a significant underpinning role across most of these technology areas,
particularly in the healthcare and life sciences sectors.
596
https://www.gov.uk/government/publications/enabling-technologies-strategy-2012-to-2015
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1 DATA STORAGE
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2 PRINTED ELECTRONICS
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6 COMPONENTS
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7 N OVEL TECHNOLOGIES
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GALLIUM NITRIDE
No relevant toxicity studies on nano-gallium nitride were encountered in public literature. Gallium
nitride wafers are virtually insoluble in water, even in dilute acid (Jewett, et al. 2012), and therefore,
applying the methodology of van Duuren et al. (2012), the hazard characteristics of the parent
597
See http://apps.echa.europa.eu/registered/data/dossiers/DISS-9eb10650-da4f-6514-e044-
00144f67d031/DISS-9eb10650-da4f-6514-e044-00144f67d031_DISS-9eb10650-da4f-6514-e044-
00144f67d031.html
598
See http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-
summary/104548
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material are used. Gallium nitride is not classified for any toxicity by the EU 599. However, this
absence of classification was based on lacking data. Besides the gallium ions, which are not
considered relevant for gallium nitride since it is insoluble in water (Foster, et al. 2013), only one
structurally similar compound was found using the on-line ChemID database: gallium phosphide,
which was characterised as being 80% similar with gallium nitride. Also on this compound no relevant
toxicity data were found, meaning read-across could not be employed. Therefore, no hazard banding
can be derived.
GRAPHENE
Graphene is composed of sp2-hybridised carbon atoms arranged in a two-dimensional structure. The
various forms of graphene include few-layer graphene, reduced graphene oxide, graphene
nanosheets and graphene oxide (GO) (Seabra, et al. 2014).
The UK government body, the Medicines and Healthcare Products Regulatory Agency (MHRA), and
the US Food and Drug Administration (FDA) are now reviewing all forms of graphene and
functionalised graphene oxide (GO) because of their poor solubility, high agglomeration, long-term
retention, and relatively long circulation time in the blood (Begum et al. 2011 cited in Nezakati, et
al. 2014).
Currently, limited information about the in vitro and in vivo toxicity of graphene is available (Seabra,
et al. 2014). The toxicity profiles of graphene and graphene oxide (GO) nanoparticles remain difficult
to separate, since their characterisation, bulk and chemical composition are very similar at the
nanometre length scale (Nezakati, et al. 2014).
In vitro graphene has been demonstrated to be cytotoxic, be it overall to a lesser degree than carbon
nanotubes (Seabra, et al. 2014). However, the reliability of this conclusion can be doubted since
Seabra et al. stated that graphene showed an inverse dose-relationship, being more cytotoxic than
carbon nanotubes at low concentrations. The only elaborate comparative study reported by Seabra
et al., refers to genotoxicity towards human fibroblast cells. GO proved to be the most potent
genotoxic agent compared to iron oxide (Fe304), titanium dioxide (Ti02), silicon dioxide (Si02), zinc
oxide (ZnO), indium (In), tin (Sn), core—shell zinc sulphate-coated cadmium selenide (CdSe (3)
ZnS), and carbon nanotubes.
Intratracheal instillation of 50 µg GO in mice caused severe pulmonary distress after inhalation
causing excessive inflammation, while the amount of non-functionalised graphene instilled did not
(Duch et al. 2011). Single intravenous (i.v.) injection of graphene oxide into mice at a dose of 10
mg/kg bw accumulated in the lung resulting in pulmonary oedema and granuloma formation, with
NOAEL of 1 mg/kg bw (Zhang, et al. 2011). Furthermore, surface functionalised graphene
(PEGylated) appears to be far less toxic: no toxic effects after single i.v. injection of 20 mg/kg bw
(Yang, et al. 2011). In mice, PEGylated GO materials showed no uptake via oral administration,
indicating limited intestinal absorption of the material, with almost complete excretion. In contrast,
upon i.p. injection in mice, PEGylated GO was found to accumulate in the liver and spleen (Yang, et
al. 2013 (cited in Seabra, et al. 2014)).
The toxicity of graphene is dependent on the graphene surface (the chemical structure or the nature
of the functionalised coatings), size, number of layers, cell type, administration route (for in vivo
experiments), dose, time of exposure, and synthesis methods (Seabra, et al. 2014). Generalisations
are therefore hard to make, but graphene nanostructures are not fibre-shaped and theoretically may
be assumed to be safer than carbon nanotubes (Seabra, et al. 2014).
Based on the scarce available evidence, and in spite of its theoretical advantage in relation to carbon
nanotubes, it cannot be excluded that some forms of graphene will be as potent a toxicant as carbon
nanotubes. Therefore, graphene is assigned to hazard band E.
MOLYBDENUM DISULPHIDE
No relevant toxicity studies on nano-molybdenum disulphide were encountered in public literature.
It is insoluble in water and therefore, applying the methodology of van Duuren et al. (2012), the
hazard characteristics of the parent material are used. Molybdenum disulphide is not classified for
599
See http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-
summary/5411.
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any toxicity by the EU600. Based on this absence of classification, the nanoforms should be assigned
hazard band C, the lowest category a nanoparticle can be assigned just based on toxicity data for
its non-nano parent compound (Van Duuren-Stuurman, et al. 2012).
TUNGSTEN SELENIDE
No relevant toxicity studies on nano-tungsten selenide were encountered in public literature.
Tungsten selenide is also not classified for any toxicity by the EU 601. However, this absence of
classification was based on lacking data. Also on the top 5 similar compounds retrieved by ChemID
(rhenium selenide, tantalum selenide, tungsten telluride, manganese selenide and molybdenum
selenide, similarity ranging from 85 to 95%) no relevant toxicity data were found, meaning read-
across could not be employed. Therefore, no hazard banding can be derived.
Overview of hazard bands of nanoparticles in the manufacturing sector
The table Hazard bands for selected nanoparticles presents an overview of selected nanoparticles of
the manufacturing sector and their hazard bands, either taken from le Feber et al. (2014) or van
Duuren et al. (2012), or derived in this report.
EXPOSURE ASSESSMENT
For the materials, manufacturing is a crucial phase regarding health and safety, due to relatively
high potentials for exposure of employees. However, the production phase was earlier described in
the sector “manufacturing” and will not be evaluated in this sector report.
Most of the engineered nanomaterials are present in the products as part of a matrix. Some of the
identified substances for evaluation may not necessarily be engineered nanomaterials. During the
manufacture of ICT products engineered nanomaterials may be used and are applied mainly as
coatings. For the majority of these coatings, only a low percentage of engineered nanomaterials are
present. The production phase of ICT products on industrial scale consists mainly of automatic
processes, with employees only engaged in product quality control or system engineering. In
addition, most processes are performed in cleanrooms and/or under well-controlled conditions, as
dust is a major threat to the quality of the products. Nevertheless, spray scenarios for coating
normally result in high exposure concentrations, so potential exposure cannot be neglected. In the
situation of a manual process without proper exposure control measures (e.g. local exhaust
ventilation, cleanroom), employees may be exposed to relatively higher concentrations. Lastly,
during the end-of-life phase several metals may be present in the ICT product, which can be
worthwhile to recycle. Recycling of these metals may involve, for example, shredding of ICT
600
See http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-
summary/37514.
601
http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-
summary/1552.
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products, and engineered nanomaterials possibly present can become airborne. However, as the
shredded products only will contain a small amount of engineered nanomaterials, potential exposure
to engineered nanomaterials during this process will be relatively low.
In conclusion, the use of ICT products results in exposure band 1 (consumers and workers), whereas
during the production of ICT products exposure band 2 (workers) is believed to be realistic.
Furthermore, during the end-of-life phase an exposure band 1 (workers) is realistic.
RISK ASSESSMENT
The hazard and exposure bands are combined to yield so called priority bands, according to the
scheme depicted in the table Priority bands in the Stoffenmanager. A high priority implies that it is
urgent to apply exposure control measures or to assess the risks more precisely, and a low priority
implies that it is not very urgent to apply exposure control measures or to establish the risk involved
with more precision. It should be emphasised that because of the scarcity of available information,
the scheme is set in a conservative way (according to the precautionary principle).
Table 2: Priority bands in the Stoffenmanager
Hazard band A B C D E
Exposure band
1 3 3 3 2 1
2 3 3 2 2 1
3 3 2 2 1 1
4 2 1 1 1 1
Key:
Hazard: A = lowest hazard and E = highest hazard;
Exposure: 1 = lowest exposure and 4 = highest exposure;
Overall result: 1 = highest priority and 3 = lowest priority (Van Duuren-Stuurman, et al. 2012)
Risks based on the hazard and exposure banding applied to the sector are listed in the table Priority
bands ICT sector. Since exposure does not vary between ICT sector categories, and the nanoparticles
may, in principle, be applied in any of these categories, they are not separately listed in this table.
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The highest priority is for graphene and crystalline silica during the production, use and end-of-life
phases, while gallium arsenide and nanosilver have intermediate priority in those phases. Molyb-
denum disulphide and amorphous silica also have intermediate priority in the production phase, but
low priority during use and end-of-life phase in view of a lesser potential of exposure in those phases.
For gallium nitride and tungsten selenide no adequate data were available to perform hazard and
exposure banding.
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carcinogenicity of gallium arsenide. Crit. Rev. Toxicol. 43, 436-466.
Duch, M.C., Budinger, G.R.S., Liang, Y.T., Soberanes, S., Urich, D., Chiarella, S.E., Campochiaro,
L.A., Gonzalez, A., Chandel, N.S., Hersam, M.C., Mutlu, G.M., 2011. Minimising oxidation and stable
nanoscale dispersion improves the biocompatibility of graphene in the lung. Nano Letters 11, 5201-
5207.
ECHA, 2012. Chapter R.14: Occupational exposure estimation, in: Anonymous Guidance on
Information Requirements and Chemical Safety Assessment., Version: 2.1 ed. European Chemicals
Agency, Helsinki, Finland.
Foster, C.M., Collazo, R., Sitar, Z., Ivanisevic, A., 2013. Aqueous stability of Ga- and N-polar gallium
nitride. Langmuir 29, 216-220.
Jewett, S.A., Makowski, M.S., Andrews, B., Manfra, M.J., Ivanisevic, A., 2012. Gallium nitride is
biocompatible and non-toxic before and after functionalisation with peptides. Acta Biomater. 8, 728-
733.
Le Feber, M., Kroese, E.D., Kuper, C.F., Stockmann-Juvala, H., Hyytinen, E.R., 2014. Pre-assigned
hazard bands for commonly used nanoparticles. TNO2014 R11884.
Marquart, H., Heussen, H., Le Feber, M., Noy, D., Tielemans, E., Schinkel, J., West, J., Van Der
Schaaf, D., 2008. 'Stoffenmanager', a web-based control banding tool using an exposure process
model. Ann. Occup. Hyg. 52, 429-441.
Nezakati, T., Cousins, B.G., Seifalian, A.M., 2014. Toxicology of chemically modified graphene-based
materials for medical application. Arch. Toxicol. 88, 1987-2012.
Seabra, A.B., Paula, A.J., De Lima, R., Alves, O.L., Durán, N., 2014. Nanotoxicity of graphene and
graphene oxide. Chem. Res. Toxicol. 27, 159-168.
Van Duuren-Stuurman, B., Vink, S., Verbist, K.J.M., Heussen, H.G.A., Brouwer, D., Kroese, D.E.D.,
Van Niftrik, M.F.J., Tielemans, E., Fransman, W., 2012. Stoffenmanager Nano version 1.0: a web-
based tool for risk prioritisation of airborne manufactured nano objects. Ann. Occup. Hyg. 56, 525-
541.
Watkinson, A.C., Bunge, A.L., Hadgraft, J., Lane, M.E., 2013. Nanoparticles do not penetrate human
skin - A theoretical perspective. Pharm. Res. 30, 1943-1946.
Yang, K., Wan, J., Zhang, S., Zhang, Y., Lee, S., Liu, Z., 2011. In vivo pharmacokinetics, long-term
biodistribution, and toxicology of pegylated graphene in mice. ACS Nano 5, 516-522.
Zhang, X., Yin, J., Peng, C., Hu, W., Zhu, Z., Li, W., Fan, C., Huang, Q., 2011. Distribution and
biocompatibility studies of graphene oxide in mice after intravenous administration. Carbon 49, 986-
995.
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Free publications:
• one copy:
via EU Bookshop (http://bookshop.europa.eu);
• more than one copy or posters/maps:
from the European Union’s representations (http://ec.europa.eu/represent_en.htm);
from the delegations in non-EU countries (http://eeas.europa.eu/delegations/index_en.htm);
by contacting the Europe Direct service (http://europa.eu/europedirect/index_en.htm) or
calling 00 800 6 7 8 9 10 11 (freephone number from anywhere in the EU) (*).
(*) The information given is free, as are most calls (though some operators, phone boxes or hotels may charge you).
Priced publications:
• via EU Bookshop (http://bookshop.europa.eu).
202
This report offers a snapshot of the environment for nanotechnology in the context
of information and communication technologies (ICT). It gives an overview of
policies and programmes for nanotechnology and ICT in the EU (and wider),
publications, patenting, research & innovation, industry, products and markets,
and the wider environment. The report is part of a series of eight NanoData
Landscape Compilation studies covering the application of nanotechnology in the
fields of construction, energy, environment, health, ICT, manufacturing, photonics
and transport.