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Classification: Cefditoren, As This Agent May Cause

Cefixime is an oral third-generation cephalosporin antibiotic prescribed for gonorrhea and other bacterial infections. It works by binding to the bacterial cell wall membrane and causing cell death. Common side effects include diarrhea and rash. The medication should be taken with food once daily for 5 days to treat gonorrhea, and as a single 400mg dose for other infections. Patients should finish the full course of medication and see a doctor if side effects occur.

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Havier Esparaguera
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59 views

Classification: Cefditoren, As This Agent May Cause

Cefixime is an oral third-generation cephalosporin antibiotic prescribed for gonorrhea and other bacterial infections. It works by binding to the bacterial cell wall membrane and causing cell death. Common side effects include diarrhea and rash. The medication should be taken with food once daily for 5 days to treat gonorrhea, and as a single 400mg dose for other infections. Patients should finish the full course of medication and see a doctor if side effects occur.

Uploaded by

Havier Esparaguera
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Prescribed Medication Prescribed Dosage, Frequency and Route of Administration:

Brand Name: Suprax 00 mg once daily; Gonorrhea—400


mg single dose.
Generic Name: Cefixime Therapeutic Dosage: 400mg /tab OD x 5 days
Drug Classification Mechanisms of Action
(General Action) Patient Teaching Nursing Responsibilities
Classification Bind to the bacterial cell wall membrane, Instruct patient to take medication around the Assess for infection (vital signs; appearance of
Therapeutic: anti-infectives causing cell clock wound, sputum, urine, and stool; WBC) at
Pharmacologic: third-generation death. Therapeutic Effects: Bactericidal and to finish the medication completely, even if beginning
cephalosporins action feeling of and throughout therapy.
against susceptible bacteria. Spectrum: better. Take missed doses as soon as possible ● Before initiating therapy, obtain a history to
Similar to unless almost time for next dose; do not double determine
that of second-generation cephalosporins, doses. Advise patient that sharing of this previous use of and reactions to penicillins or
but activity medication cephalosporins. Persons with a negative history of
against staphylococci is less, whereas may be dangerous. penicillin sensitivity may still have an allergic
activity against ● Pedi: Instruct parents or caregivers to use response.
gram-negative pathogens is greater, even calibrated ● Obtain specimens for culture and sensitivity
for organisms measuring device with liquid preparations. before
resistant to first- and second-generation ● Advise patient to report signs of superinfection initiating therapy. First dose may be given before
agents (furry overgrowth on the tongue, vaginal itching receiving
Laboratory Tests/Results Contraindications or results.
Relevant to the Medication discharge, loose or foul-smelling stools) and ● Observe for signs and symptoms of anaphylaxis
Lab Test Considerations: May allergy. (rash, pruritus, laryngeal edema, wheezing
cause positive results Hypersensitivity to cephalosporins; ● Instruct patient to notify health care continue drug and notify health care professional
for Coombs’ test in patients Serious hypersensitivity to penicillins; professional if immediately if these symptoms occur. Keep
receiving high Pedi: rash, fever and diarrhea develop, especially if epinephrine,
doses or in neonates whose mothers Premature neonates up to a postmenstrual stool an antihistamine, and resuscitation equipment
were given age of 41 wk contains blood, pus, or mucus. Advise patient not close by in the event of an anaphylactic reaction.
cephalosporins before delivery. (ceftriaxone only); Pedi: to ● Monitor bowel function. Diarrhea, abdominal
● Monitor prothrombin time and Hyperbilirubinemic neonates treat diarrhea without consulting health care cramping, fever, and bloody stools should be
assess patient for (may lead to bilirubin encephalopathy); professional. reported
bleeding (guaiac stools; check for Pedi: Neonates to health care professional promptly as a sign
hematuria, bleeding _28 days requiring calcium-containing IV of Clostridium difficile-associated diarrhea
gums, ecchymosis) daily in patients solutions (q (CDAD).
receiving risk of precipitation formation); Carnitine May begin up to several wk following cessation of
cefditoren, as this agent may cause deficiency or
hypoprothrombinemia. inborn errors of metabolism (cefditoren therapy.
● May causeqserum AST, ALT, only); Hypersensitivity ● Assess patient for skin rash frequently during
alkaline phosphatase, to milk protein (ceftidoren only; contains therapy.
bilirubin, LDH, BUN, and serum sodium Discontinue at first sign of rash; may be
creatinine. caseinate). lifethreatening.
● May rarely cause leukopenia, Stevens-Johnson syndrome may develop.
neutropenia, agranulocytosis, Treat symptomatically; may recur once
thrombocytopenia, eosinophilia, treatment is stopped.
lymphocytosis,
and thrombocytosis.
Drug-Drug Interactions Food-Drug Interactions
Drug-Drug: Probenecidpexcretion
andqserum
levels (cefdinir, cefditoren,
cefixime, cefotaxime, cefpodoxime,
ceftriaxone). Concurrent use of loop
diuretics,
aminoglycosides, or NSAIDs
mayqrisk of
nephrotoxicity.
Antacidspabsorption of cefdinir,
cefditoren,
and cefpodoxime. Iron
supplementspabsorption
of cefdinir. H2-receptor
antagonistspabsorption
of cefditoren and cefpodoxime.
Cefixime may
qcarbamazepine levels. Ceftriaxone
should not be
administered concomitantly with
any calcium-containing
solutions. Ceftriaxone mayqrisk of
bleeding with
warfarin.

MVC-SN L3 Form 03 (Jan.2017)

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