DNA Modeling Objectives:: Procedure

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MOE License No.

248/S (Boys Section)


MOE License No. 4350140107 (Girls Section)
Philippine DepEd Government Number SP-004, Series 2018

DNA Modeling
Objectives:

Identify the components of a DNA molecule

Construct a model of a molecule of DNA

Materials:

Cut outs of basic subunits of DNA

Colorpen

Scissors

Tape or glue

Procedure:
1. Cut out all of the units needed to make the nucleotides
2. Color code the nitrogenous bases, phosphorus, and sugars. Adenine = yellow,
Guanine = green, Thymine = blue, Cytosine = red, Phosphate = brown, and
Deoxyribose = . black
3. Using the small squares and stars as guides, line up the bases, phosphates and
sugars.

4. Now glue the appropriate parts together forming nucleotides.

Construct DNA model using the following sequence to form a row from top to bottom:
Thymine

Adenine

Cytosine

Guanine

Adenine

Cytosine

1. Let this arrangement represent the left half of your DNA molecule.

2. Complete the right side of the ladder by adding the complementary bases. You will
have to turn them upside down in order to make them fit.
3. Your finished model should look like a ladder.
Guide Questions:

Q1 What are the common parts of a nucleotide? __nitrogenous base, phosphate and
deoxyribose sugar

Q2 What is the one part of the nucleotide that differs among the other different
nucleotides? ___the nitrogenous base _____________________

Q3 List the different kinds of nitrogen bases___adenine, thymine, guanine and cytosine

Q4 Is there always going to be an equal number of adenine and thymine nucleotides in


molecule? Why? ___Yes, adenine always and can only pair with thymine because
of their chemical structure.____________

Q5 Is there always going to be an equal number of guanine and cytosine nucleotides


in a molecule? Why? _____ Yes, guanine can only pair with cytosine because of
their chemical nature._____________

The structure of the DNA is actually in a double helix arrangement as shown in Figure

Double helix structure of DNA

Q6 The sides of the ladder are made up of alternating __sugars___and____phosphate_____


molecules. The steps (or rungs) of the ladder are made up of ___nitrogenous bases________
held together by hydrogen bonds.

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