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    Eczema: Pathogenesis. Atopic Dermatitis Depends On A Complex Interaction Between

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    Suhas Ingale
    Eczema is a common chronic inflammatory skin condition that usually begins in childhood. It involves an interaction between genetic and environmental factors that results in an immune system imbalance. Diagnosis is based on symptoms of itchy skin and three of the following criteria: onset in infancy, history of flexural rash, other atopic diseases in family, or rash on cheeks and outer limbs in young children. Treatment involves topical corticosteroids, antihistamines, and addressing triggers like contact dermatitis. Homoeopathic remedies that may help include Hepar Sulphur, Sulphur, and Rhus Tox.

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    Eczema: Pathogenesis. Atopic Dermatitis Depends On A Complex Interaction Between

    Uploaded by

    Suhas Ingale
    131 views5 pages
    Eczema is a common chronic inflammatory skin condition that usually begins in childhood. It involves an interaction between genetic and environmental factors that results in an immune system imbalance. Diagnosis is based on symptoms of itchy skin and three of the following criteria: onset in infancy, history of flexural rash, other atopic diseases in family, or rash on cheeks and outer limbs in young children. Treatment involves topical corticosteroids, antihistamines, and addressing triggers like contact dermatitis. Homoeopathic remedies that may help include Hepar Sulphur, Sulphur, and Rhus Tox.

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    Eczema

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    Eczema is a common chronic inflammatory skin condition that usually begins in childhood. It involves an interaction between genetic and environmental factors that results in an immune system imbalance. Diagnosis is based on symptoms of itchy skin and three of the following criteria: onset in infancy, history of flexural rash, other atopic diseases in family, or rash on cheeks and outer limbs in young children. Treatment involves topical corticosteroids, antihistamines, and addressing triggers like contact dermatitis. Homoeopathic remedies that may help include Hepar Sulphur, Sulphur, and Rhus Tox.

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    © All Rights Reserved
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    Download as doc, pdf, or txt
    131 views5 pages

    Eczema: Pathogenesis. Atopic Dermatitis Depends On A Complex Interaction Between

    Uploaded by

    Suhas Ingale
    Eczema is a common chronic inflammatory skin condition that usually begins in childhood. It involves an interaction between genetic and environmental factors that results in an immune system imbalance. Diagnosis is based on symptoms of itchy skin and three of the following criteria: onset in infancy, history of flexural rash, other atopic diseases in family, or rash on cheeks and outer limbs in young children. Treatment involves topical corticosteroids, antihistamines, and addressing triggers like contact dermatitis. Homoeopathic remedies that may help include Hepar Sulphur, Sulphur, and Rhus Tox.

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    ECZEMA

    Eczema is a common endogenous form of dermatitis and usually begins in


    childhood. It is an itchy chronic and relapsing, dermatitis.

    Pathogenesis. Atopic dermatitis depends on a complex interaction between


    genes and environment. Genetic studies have shown linkage in three loci, but
    the environment in early life also has a profound influence on the immune over-
    activity that develops in this condition. An 'imbalance' in the immune system
    with preferential activation of Th2 CD4 lymphocytes seems to be a crucial
    step in the development of atopy.

    Diagnostic criteria for atopic dermatitis

    An itchy skin condition (or parenteral report of scratching or rubbing


    in a child)

    plus three or more of the following:

    Onset in infancy

    History~6T~sluh crease involvement (including cheeks) in children


    under 10 years

    Other atopic feature (or history of any atopic disease in a first-degree relative
    in children under 4 years)

    Visible flexural dermatitis (or dermatitis of cheeks/forehead and outer limbs


    in children under 4 years)

    Clinical appearances of atopic dermatitis

    Acute dermatitis Red, wet, weepy

    vesicles ,
    Subacute dermatitis Red, dry, scaly

    Chronic dermatitis Dry, thickened

    excoriated

    In, many patients, these clinical features overlap.

    Distribution - In infants eczematous lesions are often present on exposed


    areas such as the cheeks, or outer aspects of

    Distribution :- Body areas which can be easily scratched such as nape


    of neck , dorsa of feet , wrists , extensor surface of forearms , scalp
    and external ear canal.

    Treatment :-

    a. patient explanation of this habit. B. topical corticosteroids and


    occlusion of the area fore 6 – 8 hours with a plastic film to enhance
    the effect. C. Antihistamines for purities.

    Stasis Dermatitis :-

    Cl/Fs – Onset is with oedema which after sometime is followed by


    irregular parches of pigmentation. Melanin may also be deposited in
    the skin as a result of scratching . Stasis can given rise to eczema and
    venous ulceration.

    Contact dermatitis :- Contact dermatitis is and eczematous eruption


    caused by external signs :-

     Water / wet – work


     Degreasing agents.
     Detergents
     Solvents
     Metal – working fluid
     Dusts and friction
     Low humidity
     Allergenic chemicals

    Cause :- Can be broadly divided into irritant substances that have a direct
    effect on the skin , and allergic chemicals with which dermatitis follows
    delayed type IV cell mediated hypersensitivity reactions.

    Common allergens causing contact dermatitis :-

     Nickle
     Fragrance
     Rubber
     Medications including topical corticosteroids.
     Chromate
     Formaldehyde and other biocides
     Epoxy resin
     Plant allergens
     Hair dressing chemicals
    Homoeopathic Treatrment :-

     Mezerium

     Rhus Tox

     Petroleum

     Phytolacca

     Merc – So
     Hepar – Sulph

    1. Hepar Sulph :
     Indicated in pyoderma, where every little injury is suppurated.
     Eruptions starts behind the ear, behind the joints.
     Boils, abseen and papules are prone to suppurate very chilly patient.
     Cannot bear to be uncovered wants to cover every time.
     Indicated in pyoderma, abscess, rash , itch , herpes, psoriasis,
    urticaria, acne, boils.
     Sweat profusely all over body.
     Mentally Patient is very much oversensitive and irritable.
     Patient is very quick action.
     A/p abuse of mercury , quinine , suppressed , eruption, syphilis and
    gonorrhoea.
     Modalities
    < From cold air, uncovering , in general cold, lying on painful side.
    > warmth in general , from wrapping and damp wet weather.
    2. Sulphur :
    This remedy is also indicated in the pyoderma where burning in
    present anywhere and everywhere on the body.
     King of all antipsoric remedies.
     Hot patient
     Dirty , filthy look of skin, with offensive odour.
     The skin is very much sensitive to atmospheric changes.
     Severe itching with increases by scratching.
     Every little injury in suppurated.
     Standing in worse position to patient.
     Mind – Ragged philosopher, weakness of memory. Cant find proper
    word during speaking. A/F : Alcohol, suppression of skin disease, sun
    heat, over exertion etc.
     Modalities
    < standing, warmth of bed, washing, bathing, alcohol,
    changeable weather.
    > By dry warm weather and lying on right side.

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