NOMnOne |e sts aes

secreted from the arcuate

nuclei and has a half life of I-
?2 minutes

a- CRH

b- GHRH
c- Somatostatin
d- TRH

e- Dopamine @®

O a

S b

Cc Cc
 AOSNYVIGlS CYUIUNS©S Io
~ a
Pactivated by
a- GDP bearing a subunit of
G-protein

b- GTP bearing a subunit of

G-protein
c- GDP bearing y subunit of
G-protein
d- GTP bearing y subunit of
G-protein
e- GDP bearing B subunit of
G-protein
Me
; d- Somatostat In

e- Somatomedin
 A) The sound of the hungry baby’s cry elicits secretion of oxytocin from the posterior pituitary, ae
Which reaches the breast and causes contraction of the myoepithelial cells.
B) The sound of the hungry baby’s cry causes a reflex relaxation of the myoepithelial cells,
allowing the milk to flow.
: C) The sound of the hungry baby’s cry elicits a surge of prolactin from the anterior pituitary, which
My Stimulates milk production from the breast,
a D) The sound of the hungry baby’s cry elicits sympathetic nervous system discharge that causes
7” contraction of the myoepithelial cells.
 t i w w e e e 1
oi o w

Aserum thyroid panel reveals an increase in total T,,

‘normal TSH, and a normal fTs. What is the most
likely cause of these results?
a. Increased thyroxine-binding protein
b. Secondary hyperthyroidism
¢. Subclinical hypothyroidism
d. Subclinical hyperthyroidism
 s3
oS°
g
Z
3
s
z
§
a
2
S
2
5
g
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r=
2
a|
=
=
2

Insulin
iEt|
:

it
HY
Wh;
a
 a ae
FG ag i e Tae :

ost commonly used challenge test to assist in

ting a potential growth hormone deficiency

Bieslin challenge test

b. Dexamethasone suppression test
‘¢. Oral glucose tolerance test
d. Captopril suppression test
 Moc 2 patients do. Identify
| ?compounds X and Y

(Compound Y
Placebo
Placebo
SH
-
 — my7 ,
* " Pe aa ty hy
geo a =
% | on =

Q- TVvoO

b-Type2
c- Type ap
d- Any of the above
oO
Qo.
> Fi eer
evaluated for weight loss. An
ADH level is measured as
part of a research protocol.
His ADH level is low. This
would be expected in which
of the following situations
a- Ectopic ADH secretion by
a tumor
b- SIADHED

c- Nephrogenic DI
d- Hypovolemia due to
dehydration

q Ke

mp boa
 Which of the following
29sentences Is correct

a- Prolactinomas represent
40-50% of all pituitary
adenomas

b- The commonest result of

prolactinomas is a loss of
reproductive function
c- Macroprolactinomas are
present in 90% of women
d- Galactorrhea is common
in hyperthyroidism
e- All of the above
 | 0:13:27 full Bgl
, : elevated T4
concentration, a low plasma
TSH concentration, and a
thyroid gland that is smaller
than normal, which of the
following is the most likely
explanation for these
findings?
g- Patient has a lesion in the
anterior pituitary that
prevents TSH secretion
b- Patient is taking
propylthiouracil
c- Patient is taking thyroid
extract
d- Patient is consuming
large amounts of iodine
 628

&
43
O
O
=>

d- Prolactin
 Ha te in che
lodide trapping
ye sh
Binding of thyroglobulin
. Oxidation of iodine
_ Oxidation of TG molecule
 Paar a

. Evels of both TRH and TSH.

~ Her heart rate is elevated.
This patient most likely has
_ which of the following?
a- Endemic goiter
b- Hypothalamic tumor
secreting large amounts of
TRH

c- Pituitary tumor secreting

large amounts of TSH
d- Graves disease

e- Thyroid cancer
Zs Which pattern of lab findings is most consistent of diabetes insipidus, note that :
the values are 24 hour urine volumes of ketones, glucose and protein respectively —
 In the figure, line D most
likely illustrates the influence
20f which of the following
0

Irvesutery

A) Exercise @
B) Obesity
C) Growth hormone
D) Cortisol
E) Glucagon
b- Increased synthesis of
thyroglobulin
c- Increased metabolic rate

d- Decreased TSH secretion

e- Extreme nervousness
/ Were i ree ets Le

What are the actions of

?ACTH

a- Stimulates production of
adrenocortical hormones

b- Causes hyperplasia of
adrenal cortex

c- In the adrenal, it increases |

protein synthesis
d- It increases
steroidogenesis

e- All of the above

‘ ke

: b
Cc
 Which of the following
physiological responses is
greater for T3 than for T4?
a- Secretion rate from the
thyroid
D- Plasma concentration

C- Plasma half-life

d- Affinity for nuclear

receptors in target tissues ad
€- Latent period for onset of
action in target tissues

aq
iG S

_ b b @
 . ica
‘© H 0.2 pU/mL, FT; 8.9 pg/mL, FT, 4.5 ng/dL.
b TSH 8.5 Win, FT, 1.0 pg, FT, 0.5 ng/dL

13 Sige
32 dle leo ye
1.00 eyo de ystt
Which of the following pairs
is an example of paracrine
?mode of action
 sellular fluid that act o
; in the same tissue.
Which of the following refers
to
F this type of regulation?
| F a= Neural
b= Endocrine

c- Neuroendocrine

eee Poracrine aR
e- Autocrine
 Hl Hit i} i

i : '
ill
hsehic.
Trophicmn
| | Nh Ly
|

i Pituita
tuitary; hypothalamus
se oe glands; hypothalamus
 b- Palpitations
_ C- Increased respiratory rate
_ D- Increased cardiac output
E- Weight loss
 b. Cortisol
¢. Growth hormone
_d. Somatostatin @e
O

O
¢ &
ry NNI Giter delivery, not before?

a
i a+ Levels of LH and FSH are
too low during pregnancy to
support milk production
D- High levels of Gap
progesterone and estrogen
during pregnancy suppress
milk production
c- The alveolar cells of the
breast do not reach maturity
until after delivery
d- High levels of oxytocin are
required for milk production
to begin and oxytocin is not
secreted until the baby
_ Stimulates the nipple
r =A 30 year old woman reports
to the clinic for a routine
physical examination, the
examination reveals that she
is pregnant. Plasma levels of
TSH are high but total T4
concentration is normal.
Which of the following best
reflects this patient's clinical
state?
A) Graves’ disease
B) Hashimoto's diseas@iD
C) Pituitary tumor secreting TSH
D) Hypothalamic tumor secreting TRH
E) Patient is taking thyroid extract

q a

: “>
V c
d d.
A) Increased heart rate
B) Exophthalmos
C) Increased plasma levels of triiodothyronine (T3)

D) Increased plasma levels of thyroxine (T4)

E) Increased plasma levels of thyroid-stimulating hormone
ap

a @
 plagy?
Decreased levels of crculating hormones directly
_ tesult in the production of hormone from the

Increased circulating levels of hormones directly

Bie
P

result in the production of releasing factor from

Bic:
rr

the hypothalamus
— & Increased circulating levels of hormones directly
_ gesult in the producnon of inhibiting
factor from
) the hypothalamus
_ & Normal levels of circulating hormones direc tly
: result in the production of hormone from the
 following sets of
ges is most likely in this
jent after several weeks
administration?
Respiratory Heart —_ Plasma cholesterol |
rate rate concentration
-—» —

ss
<<
—

—
co
F.
:
5
¥
 All of the followings are
decreased because of the
?effects of IGF-1 except
a- Hepatic glucose uptake
b- Plasma glucose
c- Plasma ketone bodies
d- Amino acid uptakeaa®
e- Plasma free fatty acids