Generic Name: Amoxicillin Suspension Mechanism of Action Side Effects/ Adverse Reaction Nursing Responsibility

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GENERIC NAME: MECHANISM OF ACTION SIDE EFFECTS/ ADVERSE NURSING

REACTION
Amoxicillin Suspension RESPONSIBILITY
Broad-spectrum, acid-stable,
semisynthetic aminopenicillin and Body as a whole: as with other Assessment & Drug effects:
analogue of ampicillin. Acts by penicillin. Hypersensitivity (rash,
-Determine previous hypersensitivity
inhibiting mucoprotein synthesis in anaphylaxis), superinfections.
reactions to penicillin,
cell wall of rapidly multiplying
GI: Diarrhea, nausea, vomiting, cephalosporins, and other allergens
bacteria. It is bactericidal and is
pseudomembranous colitis (rare) prior to therapy
inactivated by penicillinase
Hematologic: Hemolytic anemia, -Lab tests: Baseline C&C tests prior
BRAND NAME: INDICATION:
eosinophilia, agranulocytosis (rare). to initiation of therapy, start drug
Amoxil, Apo-Amoxi
Infections of ear, nose, throat, GU pending results, periodic assessments
Skin: Pruritus, urticaria, or other skin
tract, skin, and soft tissue caused by of renal, hepatic, and hematologic
DRUG ILLUSTRATION: eruptions
susceptible bacteria. Also used in functions should be made during
uncomplicated gonorrhea. Available Special sense: Conjunctival prolonged therapy
in combination with potassium ecchymosis
-Monitor for signs and symptoms of
clavulanate, which extends
an urticarial rash (usually occurring
antibacterial spectrum of amoxicillin
within a few days after start of drug)
to include beta-lactamase-producing
suggestive of hypersensitivity
strains.
reaction. If it occurs, look for other
signs of hypersensitivity (fever,
wheezing, generalized itching,
CLASSIFICATION: CONTRAINDICATION dyspnea) and report to physician
Anti-infective, antibiotic, Hypersensitivity to penicillin; immediately.
aminopenicillin infectious mononucleosis
DOSAGE/ FREQUENCY/ -Report onset of generalized,
ROUTE
erythematous, maculopapular rash
250mg P.O TID
(ampicillin rash) to physician.
Ampicillin rash is not due to
hypersensitivity; however,
hypersensitivity should be ruled out.

-Closely monitor diarrhea to rule out


pseudomembranous colitis.

Patient and Family Education

-Take drug around the clock, do not


miss a dose, and continue therapy
until all medication is taken, unless
otherwise directed by physician

-Report onset of diarrhea and other


possible symptoms of superinfection
to physician

-Do not breastfeed while taking this


drug without consulting the
physician.

Reference/s: Nurses’ Drug Guide (Wilson B, Shannon M, Stang, C. 2004)

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