PHARMACY

Medications With Antidotes Insulin Chart

Medication Antidote Insulin Name (U-100,
Onset Peak Duration
Acetaminophen Acetylcysteine or Mucomyst except where noted)
Anticholinesterase Atropine or Pralidoxime Rapid Acting
Anticholinergic Physostigmine 30-90
Antifreeze Fomepizole, Ethanol insulin aspart 10-20 minutes 3-5 hours
minutes
Benzodiazepines Romazicon (Flumazenil) 12-15
insulin human 10-20 minutes 3 hours
Beta- Blocking Agents Mesna minutes
Calcium Channel 30-90
Calcium Chloride, Glucagon insulin glulisine 10-20 minutes 3-5 hours
Blockers minutes
Carbon Monoxide Hyperbaric, Oxygen 30-90
Coumadin Phytonadione or Vitamin K insulin lispro 10-20 minutes 3-5 hours
minutes
Cyclophosphamide Mesna Regular
Digibind or Digoxin Immune Regular 30-60 minutes 2-4 hours 5-8 hours
Digoxin
Fab Regular 30-60 minutes 2-4 hours 5-8 hours
Dopamine Rigitidine Intermediate Acting
Fluorouacil Leucovorin Calcium NPH 1-3 hours 8 hours 12-16 hours
Heparin Protamine SO4
Long Acting
Insulin Reaction IV Glucose (D50)
insulin detemir 1 hour No peak 20-26 hours
Iron Deferoxamine
insulin glargine 1 hour No peak 20-26 hours
Methotrexate Leucovorin Calcium
Narcan ( Naloxone) or Ultra Long Acting
Narcotics insulin glargine U-300 6 hours No peak 36 hours
Nalmefene
Narcan ( Naloxone) or Mixtures
Opiod Analgesics 50% lispro protamine/50%
Nalmefene 10-15 minutes Varies 10-16 hours
Organophosphate Atroppine, Pralidoxime insulin lispro
Insulin and Glucose, NaHCO3, 75% lispro protamine/25%
Potassium 10-15 minutes Varies 10-16 hours
Albuterol inhaler insulin lispro
Succinylcholine Respiratory support 70% aspart protamine/30%
5-15 minutes Varies 10-16hours
Tensilon Atropine Sulfate insulin aspart
Tylenol Acetylcysteine 70% NPH/30% Regular 30-60 minutes Varies 10-16 hours
Warfarin Phytonadione or Vitamin K 70% NPH/30% Regular 30-60 minutes Varies 10-16 hours
Cardiac Drips
Drug Dosage Use
Load: 4-5 gm/1 hour, Then 1 gm/hour for 8 hours. • Don’t
Amicar Inhibit fibronolysis • Reduce post op bleeding
exceed 30 gm/day
150 mg bolus over 10 min • 1mg/min for 6 hours • 0.5 mg/min
Amiodarone Treatment for VF/VT, antiarrhythmic
for 18 hours • Don’t exceed 2.2gm/24 hours
Diltiazem 2.5-15mg/hr • Don’t exceed 24 hours Decrease HR & BP, Antiarrhythmic
Dobutamine 0.5-20/mcg/kg/min Increase CO, Increase BP
Low: Increased renal blood flow, increased UOP
1-5 mcg/kg/min for low dose
Med: May increase renal blood flow, CO, HR, and contractility
Dopamine 5-15mcg/kg/min for med dose
High: May increase BP and stimulate vasoconstriction, may not
20-150 mcg/kg/min for high dose
increase BP, may increase risk of tachyarrhythmias
2-20 mg/min
Epinephrine Increase HR and BP
0.01-0.5 mg/kg/min
Load: 250-500 mcg/kg over 1 min
Esmolol Decrease HR & BP, Antiarrhythmic, Treat SVT
50-300 mcg/kg/min
Labetalol 1-8 mg/min Treat hypertensive emergency
Load: 50 mcg/kg over 10-30 min
Milrinone Vasodilator, Increase HR & CO
0.375-0.75 mcg/kg/min
Nicardipine 2.5 mg/hr Decrease BP
Nitroglycerine 10-400 mcg/min • 0.2-5mcg/kg/min Vasodilator, Decreases BP
Norepinephrine 5-30 mcg/min • 0.01-0.5 mcg/kg/min Increase BP
Bolus: 5-20 mcg/kg IV Q10-15 min • 40-300 mcg/min • 0.1-0.5
Phenylphrine Increase BP
mcg/kg/min
Vasopressin 0.01-0.04 units/min Increase BP
www.NurseNation.net • These charts are for reference only.
Nurse Nation is not responsible for decisions made based on this information. • Local policy should supersede. • COPYRIGHT NURSE NATION 2020
 PHARMACY
Common Medications with OBSTETRICS
Classifications Oxytocin
Assess uterus for tetanic contraction
Classification / Monitor fetal heart rate
Nursing Considerations Tocolytic (stop contractions)
Example
ANALGETICS Terbutaline Don’t give before 20 weeks
Monitor fetal heart rate
Do not give with other anticoagulants
ANTIFUNGAL
Aspirin Don’t take before surgery
Don’t give to children with viral infections IVPB Slow
Monitor for renal damage
NSAIDs (Ibuprofen) Contraindicated with GI ulcers Amphotericin B
Increase fluid intake
Opioids (Morphine) Respiratory depressant Assess hearing
ANTICONVULSANTS ANTICHOLINERGICS
Gum hyperplasia - Regular dental check-ups GI - slows motility
Dilantin
Monitor therapeutic levels Eyes - dilates pupils
Atropine
ANTI-INFLAMMATORY Cardiac - increase heart rate
Immunosuppression Respiratory - bronchodilation
Cushing-like symptoms ONCOLOGICAL MEDICATIONS
Prednisone Use extreme caution
Hyperglycemia
Osteoporosis Chemotherapy Wear gloves and mask while mixing and
ANTICOAGULANT administering
Heparin aPTT ANTI-GOUT
Increase fluid intake
Warfarin PT / INR Allopurinol
Increased urine output
ANTI-PARKINSONIAN Colchicine May cause bloody diarrhea if toxicity occurs
Benztropine Treats extrapyramidal symptoms
Carbidopa/Levodopa Effective in the absence of tremors
Therapeutic Drug Levels
Drug Therapeutic Level
BETA BLOCKERS
Do not stop abruptly Acetaminophen (Tylenol) 10 - 20 mcg/mL
Propranolol Carbamazepine (Tegretol) 4 - 10 mcg/mL
Masks signs of hypoglycemia
POTASSIUM SUPPLEMENTS Digoxin (Lanoxin) 0.5 - 2.0 ng/mL
Check labs prior to administration Gentamycin (Garamycin) 5 - 10 mcg/mL
Potassium Chloride Never give IV push Lithium (Eskalith) 0.5 - 1.2 mEq/L
Do not give with renal failure Magnesium Sulfate 4 - 7 mg/dL
BRONCHODILATOR Phenobarbital (Solfoton) 15 - 40 mcg/mL
Theophylline Monitor therapeutic levels Phenytoin (Dilantin) 10 - 20 mcg/dL
Monitor for tachycardia and tremors Salicylate 15 - 30 mg/dL
Albuterol Theophylline (Aminophylline) 10 - 20 mcg/dL
May also decrease potassium levels
CARDIAC GLYCO SIDE Tobramycin (Tobrex) 5 - 10 mcg/mL
Toxicity - Visual changes, loss of appetite Valproic Acid (Depaken) 50 - 100 mcg/mL
Digoxin Assess apical pulse for a minute prior to Vancomycin (Vancocin) 20 - 40 mcg/mL
administering Drug Schedule
ANTI-ECLAMPTIC Schedule Description Examples
Used in Preeclampsia High potential for abuse. No currently MDMA, LSD,
Monitor deep tendon reflexes I
Magnesium Sulfate accepted medical use. GHB
Assess for respiratory depression High potential for abuse, but with
Seizure precations Morphine,
II some accepted medical uses in the
cocaine, Opium
DIURETICS US. Requires written prescription
Potassium wasting Potential for abuse, but lower than Ketamine,
Furosemide previous categories. Requires new codeine,
Monitor Potassium levels III
Potassium sparing prescription after 6 months or five anabolic
Spironolactone refills steroids
Monitor Potassium Levels
Relatively low potential for abuse.
PSYCHOTROPICS Benzodia-
Accepted medical uses in the US.
Therapeutic range 0.8 - 1.2 IV zepines,
Lithium Requires new prescription after 6
Increase fluid intake phenobarbital
months.
MAOI’s Avoid foods with Tyramine Low potential for abuse. Accepted Pyrovalerone,
V
Disulfiram Avoid alcohol intake of any kind medical uses in the US retigabine
www.NurseNation.net • These charts are for reference only.
Nurse Nation is not responsible for decisions made based on this information. • Local policy should supersede. • COPYRIGHT NURSE NATION 2020