مرجع شامل لكل رموز ومصطلحات التحاليل الطبية
مرجع شامل لكل رموز ومصطلحات التحاليل الطبية
مرجع شامل لكل رموز ومصطلحات التحاليل الطبية
Abbreviations Used in
Laboratory Diagnosis
A/G ratio = Albumin Globulin ratio
BT = Bleeding Time
Cl = Chloride
CK-MB = CK – isoenzyme
CT = Clotting Time
Fe = Ferrous (iron)
HCT = Hematocrit
LH = Luteinizing Hormone
T3 = Tri iodothyronine
T4 = Thyroxin
TG = Triglycerides
HEMOGLOBIN (HGB)
Normal Adult Female Range: 12 - 16 g/dl
Optimal Adult Female Reading: 14 g/dl
Normal Adult Male Range: 14 - 18 g/dl
Optimal Adult Male Reading: 16 g/dl
Normal Newborn Range: 14 - 20 g/dl
Optimal Newborn Reading 17 g/dl
MCH (Mean Corpuscular Hemoglobin)
Normal Adult Range: 27 - 33 pg
Optimal Adult Reading: 30
PLATELET COUNT
Normal Adult Range: 130 - 400 thous/mcl
Optimal Adult Reading: 265
Higher ranges are found in children, newborns and infants
Electrolyte Values
SODIUM
- Sodium is the most abundant Cation in the blood and its
chief base. It functions in the body to maintain osmotic
pressure, acid-base balance and to transmit nerve
impulses. Very Low value: seizure and Neurologic Sx.
POTASSIUM
- Potassium is the major intracellular Cation. Very low
value: Cardiac arrhythmia.
CHLORIDE
- Elevated levels are related to acidosis as wells too much
water crossing the cell membrane
Discussion
Chloride contributes to the body’s acid/base balance.
Along with Sodium, Potassium and Carbon Dioxide, it is
important in evaluating acid/base relationships, state of
hydration, adrenal and renal functions. Its level varies
inversely with Carbon Dioxide. Chloride elevation indicates
acidosis, decrease indicate alkalosis.
CALCIUM
- involved in bone metabolism, protein absorption, fat
transfer muscular contraction, transmission of nerve
impulses, blood clotting and cardiac function. Regulated by
parathyroid.
Normal Adult Range: 8.5-10.3 mEq/dl
Optimal Adult Reading: 9.4
Discussion
MAGNESIUM
Optimal Range: 2-3 mg/DL
Discussion
The serum magnesium is not reflective of total magnesium
stores. Unfortunately there is not a good test for
magnesium, but a red cell Mg level is preferable to serum
magnesium. Approximately 2/3 to ¾ of magnesium in blood
is not attached to protein.
PHOSPHORUS
- Generally inverse with Calcium.
ANION GAP
(Sodium + Potassium - CO2 + Chloride) - An increased
measurement is associated with metabolic acidosis due to
the overproduction of acids (a state of alkalinity is in
effect). Decreased levels may indicate metabolic alkalosis
due to the overproduction of alkaloids (a state of acidosis
is in effect).
SODIUM / POTASSIUM
Normal Adult Range: 26 - 38 (calculated)
Optimal Adult Reading: 32
hepatic enzymes
AST (Serum Glutamic- Oxalocetic
Transaminase - SGOT
) Found primarily in the liver, heart, kidney, pancreas, and
muscles. Seen in tissue damage, especially heart and live
Normal Adult Range: 0 - 42 U/L
Optimal Adult Reading: 21
ALKALINE PHOSPHATASE
- Used extensively as a tumor marker it is also present in
bone injury, pregnancy, or skeletal growth (elevated
readings. Low levels are sometimes found in hypoadrenia,
protein deficiency, malnutrition and a number of vitamin
deficiencies
Normal Adult Range: 20 - 125 U/L
Optimal Adult Reading: 72.5
Normal Children's Range: 40 - 400 U/L
Optimal Children's Reading: 220
TOTAL BILIRUBIN
Renal Related:-
B.U.N. (Blood Urea Nitrogen
) - Increases can be caused by excessive protein intake,
kidney damage, certain drugs, low fluid intake, intestinal
bleeding, exercise or heart failure. Decreased levels may be
due to a poor diet, malab % sorption, liver damage or low
nitrogen intake.
Normal Adult Range: 7 - 25 mg/dl
Optimal Adult Reading: 16 mg/DL
CREATININE
- Low levels are sometimes seen in kidney damage, protein
starvation, liver disease or pregnancy. Elevated levels are
sometimes seen in kidney disease due to the kidneys job of
excreting creatinine, muscle degeneration, and some drugs
involved in impairment of kidney function,
Discussion
URIC ACID
- High levels are noted in gout, infections, kidney disease,
alcoholism, high protein diets, and with toxemia in
pregnancy. Low levels may be indicative of kidney disease,
malabsorption, poor diet, liver damage or an overly acid
kidney.
Normal Adult Female Range: 2.5 - 7.5 mg/dl
BUN/CREATININE
- This calculation is a good measurement of kidney and
liver function.
Normal Adult Range: 6 -25 (calculated)
Protein:-
TOTAL PROTEIN
- Decreased levels may be due to poor nutrition, liver
disease, malabsorption, diarrhea, or severe burns.
Increased levels are seen in lupus, liver disease, chronic
infections, alcoholism, leukemia, tuberculosis amongst
many others.
Normal Adult Range: 6.0 -8.5 g/dl
Optimal Adult Reading: 7.25
ALBUMIN
- major constituent of serum protein (usually over 50%).
High levels are seen in liver disease (rarely) , shock,
dehydration, or multiple myeloma. Lower levels are seen in
poor diets, diarrhea, fever, infection, liver disease,
inadequate iron intake, third-degree burns and edemas or
hypocalcaemia
Normal Adult Range: 3.2 - 5.0 g/dl
Optimal Adult Reading: 4.1
GLOBULIN
- Globulins have many diverse functions such as, the
carrier of some hormones, lipids, metals, and antibodies
(IgA, IgG, IgM, and IgE). Elevated levels are seen with
chronic infections, liver disease, rheumatoid arthritis,
myelomas, and lupus are present, . Lower levels in immune
compromised patients, poor dietary habits, malabsorption
and liver or kidney disease.
Normal Adult Range: 2.2 - 4.2 g/dl (calculated)
Optimal Adult Reading: 3.2
Discussion
Discussion
TRIGLYCERIDES
- Increased levels may be present in atherosclerosis,
hypothyroidism, liver disease, pancreatitis, myocardial
infarction, metabolic disorders, toxemia, and nephrotic
syndrome. Decreased levels may be present in chronic
obstructive pulmonary disease, brain infarction,
hyperthyroidism, malnutrition, and malabsorption.
Normal Adult Range: 0 - 200 mg/dl
Optimal Adult Reading: 100
Thyroid:-
THYROXINE (T4)-
Increased levels are found in hyperthyroidism, acute
thyroiditis, and hepatitis. Low levels can be found in
Cretinism, hypothyroidism, cirrhosis, malnutrition, and
chronic thyroiditis.
Normal Adult Range: 4 - 12 ng/dl
Optimal Adult Reading: 8 ng/dl
Cardiac:-
Creatine phosphokinase (CK)
- Levels rise 4 to 8 hours after an acute MI, peaking at 16 to
30 hours and returning to baseline within 4 days
25-200 U/L
32-150 U/L
CK-MB CK isoenzyme
- It begins to increase 6 to 10 hours after an acute MI, peaks
in 24 hours, and remains elevated for up to 72 hours.
< 12 IU/L if total CK is <400 IU/L
<3.5% of total CK if total CK is >400 IU/L
GLUCOSE -
Causes of Decreased
Excess insulin (insulinoma, over dosage)
Impaired glucose tolerance (post-prandial)
Late/large malignancies
Endocrine hypo function (thyroid, adrenal cortex, anterior
pituitary)
Protein malnutrition
Sometimes in pregnancy
Liver dysfunction
After gastric surgeries (altered gastric emptying)
By.AmrKamal
IRON
Causes of Increased
Ineffective erythropoiesis (thalassemias, sideroblastic)
Intra-vascular hemolysis
Liver disease (alcohol, portocaval shunts)
Excessive iron intake
Causes of Decreased
Iron deficiency (low ferritin level; nutritional, blood loss, ,
small bowel disease, increased demand)
Chronic disease (liver dysfunction, renal dysfunction, etc.)
Discussion
By.AmrKamal
Alkaline Phosphates
42-98 units/L
Levels increase in pregnancy 11-128 units/L
(peaking in the 3<sup>rd trimester. Further increases may
be seen when there is liver impairment.
Amylase
1) Serum amylase rises gradually during pregnancy until
the twenty-fifth week and thereafter falls slightly
(2) Serum amylase values in normal pregnant women in the
second and third trimesters may exceed those seen in
normal men and nonpregnant women
(3) During the second trimester of pregnancy there may be
an alteration in the relative distribution of the pancreatic
and salivary-type isoamylases with the salivary type
tending to dominate. Knowledge of these changes is of
importance in the clinical assessment of serum amylase
values in pregnant women complaining of abdominal pain
and other symptoms suggestive of acute pancreatitis
Bleeding Time
2-7 minutes
>11 minutes are of concern
Calcium (Ca)
Serum 8.4-10.2mg/dL
Differential
Segs 53-79%; Bands 1-10 %;Eos 0-4%;Lymphs 13-
46%;Monos 3-9%;Basos 0-1%
Serum Cortisol
5-25ug/dl (138-690 nmol/L) in the morning and 3-13ug/dl
(83-359 nmol/L in the evening.
Creatinine (serum)
0.6-1.2 mg/dl
Pregnancy 0.4-0.8 mg/dl.
Creatinine > 1 mg/dL signifies renal dysfunction in
pregnancy
Serum electrolytes
Chloride 98-109 mEq/L
Sodium 137-145mEq/L
Potassium 3.5- 5.0 mEq/L
Bicarbonate 18-21 mmol/L
Potassium decreases 0.1-0.2mEq/L and Sodium decreases
2-3 mEq/L
Coagulation Factors
I Fibrinogen Changes in pregnancy 4.0-6.5 g/l
II Prothrombin Changes in pregnancy 100-125%
IV Ca.++ - No change
V Proaccelerin -.changes in pregnancy100-150%
VII Proconvertin-Changes in pregnancy 150-250%
Glycohemoglobin
Hgb A1C 3.6- 4.9%; Hgb A1 5.1-7.8%
Iron
Iron 50-132ug/dl;
Iron binding capacity
265-411ug/dl
Iron saturation
20-55%;
Transferrin
200-400mg/dl
Lipase
4-24u/dl
Magnesium
(You must know what units your laboratory are using,
mg/dL, mEq/l or mmol/L)
Phosphorus
2.5-5.0mg/dl
Plasma levels of inorganic phosphorus do not change
appreciably from nonpregnant levels.
Platelet Count
135,000-150,000/mm
Mild Gestational Thrombocytopenia Plt. Count 100,000-
149,000/mm
Moderate Gestational Thrombocytopenia Plt. Count 50,000-
99,000/mm
Profound Gestational Thrombocytopenia Plt. Count <50,000
Thrombin Time
Normal within 5 sec. of control
Thyroid Functions
Tyroxine (T4)5.0 12.6ug/dl
Free Thyroxine(FreeT4)1.6-2.4ng/dl;
Triiodothyronine (FreeT3) 125-300pg/dl;
Thyroid Stimulating Hormone (TSH) 0.5-3.8 uU/ml
Venous blood was tested for human chronic gonadotropin
(hCG), thyroid-stimulating hormone (TSH), free thyroxin
(FT4) and total triiodothyronine (TT3). Early pregnancy
thyroid function tests showed a significant decrease (p <
0.001) in TSH and a significant increase (p < 0.001) in TT3
as compared to the nonpregnant state; FT4, however, did
not change significantly. In 8 (11.2%) pregnant subjects,
TT3 levels were above the normal range for nonpregnant
controls. Elevated thyroid function in early pregnancy is
transient, and does not usually warrant antithyroid
treatment. Thus, any conclusion regarding thyroid function
in early pregnancy should be based on pregnant controls
rather than general population controls.
Uric Acid
By.AmrKamal
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