BIOdifference Between Meiosis and Mitosis

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Mitosis Meiosis

1 Mitosis takes place within somatic cells (cells that make Meiosis takes place within gamete cells (sex cells).
up the body).

2 One single division of the mother cell results in two Two divisions of the mother cell result in four meiotic
daughter cells. products or haploid gametes.
3 A mitotic mother cell can either be haploid or diploid. A meiotic mother cell is always diploid.

4 The number of chromosomes per nucleus remains the The meiotic products contain a haploid (n)
same after division. number of chromosomes in contrast to the (2n) number
of chromosomes in mother cell.
5 It is preceded by a S-phase in which the amount of DNA In meiosis, only meiosis I is preceded by a S-phase.
is duplicated.

6 In mitosis, there is no pairing of homologous During prophase I, complete pairing of all homologous
chromosomes. chromosomes takes place.

7 There is no exchange of DNA (crossing-over) between There is at least one crossing-over or DNA exchange per
chromosomes. homologous pair of chromosomes.

8 The centromeres split during anaphase. The centromeres do separate during anaphase II, but not
during anaphase I.

9 The genotype of the daughter cells is identical to that of Meiotic products differ in their genotype from the
the mother cells mother cell.
10 After mitosis, each daughter cell has exactly same DNA After meiosis, each daughter cell has only half of the DNA
strands. strands

DNA duplication occurs in both mitosis and meiosis. This duplication occurs during S-phase of mitosis as well as S-phase of
meiosis I. The difference between mitosis and meiosis can only be understood if we have a brief idea of what these two
cell division processes are:
Mitosis: Mitosis is the cell division process in which a eukaryotic cell divides the chromosomes into two identical sets of
two daughter nuclei in its cell nucleus. It is followed by cytokinesis, which equally divides the nuclei, cytoplasm, organelles
and cell membrane into two daughter cells. Mitosis and cytokinesis together form the mitotic (M) phase of the cell cycle.
The sequence of events is divided into different stages named as prophase, prometaphase, metaphase, anaphase and
telophase. Mitosis occurs in different ways in different species. For example, animals undergo an open mitosis process in
which the nuclear envelope breaks down before the chromosomes separate, while fungi and yeast undergo a closed
mitosis in which the chromosomes divide within an intact cell nucleus.
Meiosis:Meiosis is a process of reductional division in which the number of chromosomes per cell is halved. Before it
begins, the DNA in the original cell is duplicated during S-phase of the cell cycle. Meiosis separates the replicated
chromosomes into four haploid gametes or spores. If it produces gametes, these cells should fuse during fertilization to
create a new diploid cell or zygote. In plants, meiosis produces spores which results in the formation of haploid cells that
can divide vegetatively without undergoing fertilization. The different stages involved in meiosis are meiosis I, prophase I,
metaphase I, anaphase I, telophase I and meiosis II. Meiosis is necessary for sexual reproduction and therefore occurs in all
eukaryotes that reproduce sexually. Meiosis does not occur in archaea or bacteria as they reproduce asexually through
binary fission process.
The differences between mitosis and meiosis are as follows:

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