Name: Mrs. SABA 681 Patient UID.: 816567: Biochemistry Test Name Results Unit Bio. Ref. Interval

Name : Mrs. SABA 681 Patient UID.
: 816567
Age/Gender : 30 Yrs/Female Visit No. : 14772112100007
Referred Client : LDPL2030-LDPL SRINAGAR Collected on : 10-Dec-2021 03:08PM
Referred By : SELF Received on : 10-Dec-2021 03:08PM
Doctor Name : Reported on : 10-Dec-2021 04:39PM
Sample Type : Serum - JK22777
BIOCHEMISTRY
Test Name Results Unit Bio. Ref. Interval
AMYLASE,SERUM 51.00 U/L 28-100
: Spectrophotometry
COMMENT
Amylase is an enzyme that catalyses the hydrolysis of starch into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the
chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed
because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase (alpha amylase) to hydrolyse dietary starch into disaccharides
and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. As diastase,
amylase was the first enzyme to be discovered and isolated (by Anselme Payen in 1833)
CLINICAL NOTES
Amylase is produced in the Pancreas and most of the elevation in serum is due to increased rate of Amylase entry into the blood stream / decreased rate of clearance or
both. Serum Amylase rises within 6 to 48 hours of onset of Acute pancreatitis in 80% of patients, but is not proportional to the severity of the disease.Approximately 20% of
patients with Pancreatitis have normal or near normal activity. Hyperlipemic patients with Pancreatitis also show spuriously normal Amylase levels due to suppression of
Amylase activity by triglyceride.
Increased Amylase levels are seen in

-Pancreatitis
-Blockage of pancreatic duct by gall stones
-Pancreatic tumors(rare)
Low Amylase levels are seen in

-Chronic Pancreatitis,
-Congestive Heart failure,
-2nd & 3rd trimesters of pregnancy,
-Gastrointestinal cancer &
-bone fractures.
LIPASE
LIPASE,SERUM 52.00 U/L 10.0 - 60.0
Methodology: Spectrophotometry
Useful For
Investigating pancreatic disorders, usually pancreatitis
Clinical Information
Lipases are enzymes that hydrolyze glycerol esters of long-chain fatty acids and produce fatty acids and 2-acylglycerol. Bile salts and a cofactor, colipase, are required for
full catalytic activity and greatest specificity. The pancreas is the primary source of serum lipase. Both lipase and colipase are synthesized in the pancreatic acinar cells and
secreted by the pancreas in roughly equimolar amounts. Lipase is
filtered and reabsorbed by the kidneys. Pancreatic injury results in increased serum lipase levels.
Interpretation
In pancreatitis, lipase becomes elevated at about the same time as amylase (in 4-8 hours). But lipase may rise to a greater extent and remain elevated much longer (7-10
days) than amylase.
Elevations 2 to 50 times the upper reference have been reported. The increase in serum lipase is not necessarily proportional to the severity of the attack. Normalization is
not necessarily a sign of resolution.
In acute pancreatitis, normoamylasemia may occur in up to 20% of such patients. Likewise, the existence of hyperlipemia may cause a spurious normoamylasemia. For
these reasons, it is suggested that the 2 assays complement and not exclude each other, and that both enzymes should be assayed.
Cautions
Patients should be fasting before the specimen is drawn.
Page 1 of 2
Name : Mrs. SABA 681 Patient UID. : 816567
Age/Gender : 30 Yrs/Female Visit No. : 14772112100007
Referred Client : LDPL2030-LDPL SRINAGAR Collected on : 10-Dec-2021 03:08PM
Referred By : SELF Received on : 10-Dec-2021 03:08PM
Doctor Name : Reported on : 10-Dec-2021 04:39PM
Sample Type : Serum - JK22777
Collection tubes with glycerol-lubricated stoppers or tubes containing citrate, oxalate, or EDTA should not be used.
Certain drugs such as cholinergics and opiates may elevate serum lipase.
Renal disease may elevate the serum lipase
*** End Of Report ***
Page 2 of 2

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Increased Amylase levels are seen in

Low Amylase levels are seen in

* End Of Report *

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