Drug Study - Clarithromycin

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University of St.

La Salle
College of Nursing

DRUG STUDY

Name of Student: ______________________________________Section


Trisha L. Matula BSN-3G
and Group: ________________________
Name of CI: ___________________________________________
Hanna B. Gella Area of Exposure: _________________________
Dosage/Frequency/Timing/ Nursing
Name of Drug Mechanism of Action Indication Contraindication Adverse Effect
Route Responsibilities

Generic Name: Clarithromycin is first Intravenous Contraindicated 1. Maintain


500 mg PO BID
Clarithromycin metabolized to 14-OH Respiratory to patients who  Diarrhea adequate
clarithromycin, which tract have known  Nausea hydration.
is active and works infections, hypersensitivity 2. Advise
 Vomiting
synergistically with its Skin and to macrolides patient
soft tissue  Stomach
parent compound. antibiotics. pain about the
infections
Like other macrolides, Contraindicated likelihood
 Heartburn
Brand Name: it then penetrates to certain heart of GI
.
Biaxin bacteria cell wall and problems Qt reactions,
 Gas.
reversibly binds to prolongation. including
domain V of the 23S Contraindicated  Change in nausea,
taste.
ribosomal RNA of the to patient who diarrhea,
50S subunit of the have electrolyte  Headache. indigestion,
bacterial ribosome, imbalance (e.g abnormal
Classification: blocking translocation low potassium or taste, and
macrolide of aminoacyl transfer- sodium level) abdominal
antibiotics RNA and polypeptide pain.
synthesis. 3. Instruct
Clarithromycin also patient to
inhibits the hepatic report
microsomal CYP3A4 severe or
isoenzyme and P- prolonged
glycoprotein, an GI
energy-dependent problems.
drug efflux pump. 4. Monitor
and record
vital signs.

Reference:

 MIMS, clarithromycin, Retrieved August 15, 2022 at https://www.mims.com/philippines/drug/info/clarithromycin?mtype=generic


 Drug bank online, clarithromycin, Retrieved August 15, 2022 at https://go.drugbank.com/drugs/DB01211
 Scribd, Clarithromycin Drug Study, Retrieved august 15, 2022 https://www.scribd.com/doc/184102754/clarithromycin-drug-study

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