1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections.
2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis.
3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.
1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections.
2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis.
3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.
1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections.
2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis.
3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.
1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections.
2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis.
3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.
Name of Student: ______________________________________Section
Trisha L. Matula BSN-3G and Group: ________________________ Name of CI: ___________________________________________ Hanna B. Gella Area of Exposure: _________________________ Dosage/Frequency/Timing/ Nursing Name of Drug Mechanism of Action Indication Contraindication Adverse Effect Route Responsibilities
Generic Name: Clarithromycin is first Intravenous Contraindicated 1. Maintain
500 mg PO BID Clarithromycin metabolized to 14-OH Respiratory to patients who Diarrhea adequate clarithromycin, which tract have known Nausea hydration. is active and works infections, hypersensitivity 2. Advise Vomiting synergistically with its Skin and to macrolides patient soft tissue Stomach parent compound. antibiotics. pain about the infections Like other macrolides, Contraindicated likelihood Heartburn Brand Name: it then penetrates to certain heart of GI . Biaxin bacteria cell wall and problems Qt reactions, Gas. reversibly binds to prolongation. including domain V of the 23S Contraindicated Change in nausea, taste. ribosomal RNA of the to patient who diarrhea, 50S subunit of the have electrolyte Headache. indigestion, bacterial ribosome, imbalance (e.g abnormal Classification: blocking translocation low potassium or taste, and macrolide of aminoacyl transfer- sodium level) abdominal antibiotics RNA and polypeptide pain. synthesis. 3. Instruct Clarithromycin also patient to inhibits the hepatic report microsomal CYP3A4 severe or isoenzyme and P- prolonged glycoprotein, an GI energy-dependent problems. drug efflux pump. 4. Monitor and record vital signs.
Reference:
MIMS, clarithromycin, Retrieved August 15, 2022 at https://www.mims.com/philippines/drug/info/clarithromycin?mtype=generic
Drug bank online, clarithromycin, Retrieved August 15, 2022 at https://go.drugbank.com/drugs/DB01211 Scribd, Clarithromycin Drug Study, Retrieved august 15, 2022 https://www.scribd.com/doc/184102754/clarithromycin-drug-study