University of St.

La Salle
College of Nursing

DRUG STUDY

Kyle D. Cañada
Name of Student: _________________________________________________________________ BSN2C Group 1
Section and Group: ________________________
Ms. Cassie Mendoza RN, MN
Name of CI: ______________________________________________________________________ OB Ward
Area of Exposure: _________________________

Dosage/Frequency/ Mechanism of
Name of Drug Indication Contraindication Adverse Effect Nursing Responsibilities
Timing/Route Action

Generic Name: DOSAGE: 4 grams Magnesium sulfate -Used for immediate -If any known CNS: Confusion,  Check serum
Magnesium is thought to control of life- hypersensitivity reaction decreased reflexes, magnesium level prior
Sulfate FREQUENCY: function by threatening to magnesium sulfate has dizziness, syncope to administration.
Stat inducing cerebral convulsions in the occurred in the past, it CV: Arrhythmias,  Cardiac monitor
vasodilation, which treatment of severe should not be hypotension should be used on
TIMING: To be patients receiving
reduces ischemia toxemias (pre- administered. GI: Flatulence,
MgSO4 intravenously.
given slowly over caused by cerebral eclampsia and vomiting
 Have injectable form
15-30 minutes vasospasm during eclampsia) of -If a patient is in a known MS: Muscle cramps
of calcium gluconate
an eclamptic pregnancy and in the heart block, magnesium 710 mannitol
available to reverse
ROUTE: IV incident. The treatment of acute sulfate should not be RESP: Dyspnea,
paralyzing effects of
Brand Name: material also nephritis in children. given as it can exacerbate respiratory depression magnesium sulfate.
MgSO4 competes with the already slowed or paralysis  Blood pressure may
calcium to keep it - Indicated for cardiac conduction. SKIN: Diaphoresis drop if MgSO4 is
from accessing magnesium deficiency OTHER: Allergic administered too
synaptic endings, replacement therapy, - Because of the potential reaction, rapidly.
altering especially in acute for interference with hypermagnesemia,  Check blood pressure
neuromuscular hypomagnesemia with neuromuscular blocking injection-site pain or and pulse every 10-15
transmission. tetany symptoms agents given irritation (I.M. form), minutes during
intraoperatively, several laxative dependence, therapy.
similar to
 Normal serum plasma
Classification: hypocalcemia. Often manufacturers suggest magnesium toxicity level of MgSO4 is 1.8
Electrolyte used as a myometriat withdrawing magnesium – 3.0 mEq/L. 
replacement relaxant in uterine sulfate infusions in Respiratory paralysis
(anticonvulsant, tetany. patients with occurs at 12-15
antidysrhythmic preeclampsia/eclampsia mEq/L.  Cardiac
arrest occurs at 25
) two hours before fetal
mEq/L.
delivery; however, the
 Assess patellar
drug should not be
reflexes hourly to
stopped due to the risk of
monitor for evidence
seizure activity. of toxicity.
 Monitor hourly urine
output.
 Do not breast feed
while receiving
MgSO4.